FI57594C - Foerfarande foer framstaellning av antiallergiskt verksamma n-(bentstiazol-2-yl)-oxamidsyra-derivat - Google Patents

Foerfarande foer framstaellning av antiallergiskt verksamma n-(bentstiazol-2-yl)-oxamidsyra-derivat Download PDF

Info

Publication number
FI57594C
FI57594C FI773738A FI773738A FI57594C FI 57594 C FI57594 C FI 57594C FI 773738 A FI773738 A FI 773738A FI 773738 A FI773738 A FI 773738A FI 57594 C FI57594 C FI 57594C
Authority
FI
Finland
Prior art keywords
melting point
mol
methoxy
ethyl ester
benzthiazol
Prior art date
Application number
FI773738A
Other languages
English (en)
Finnish (fi)
Other versions
FI773738A (fi
FI57594B (fi
Inventor
Werner Winter
Max Thiel
Androniki Roesch
Otto-Henning Wilhelms
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of FI773738A publication Critical patent/FI773738A/fi
Publication of FI57594B publication Critical patent/FI57594B/fi
Application granted granted Critical
Publication of FI57594C publication Critical patent/FI57594C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI773738A 1976-12-14 1977-12-12 Foerfarande foer framstaellning av antiallergiskt verksamma n-(bentstiazol-2-yl)-oxamidsyra-derivat FI57594C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2656468 1976-12-14
DE19762656468 DE2656468A1 (de) 1976-12-14 1976-12-14 N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
FI773738A FI773738A (fi) 1978-06-15
FI57594B FI57594B (fi) 1980-05-30
FI57594C true FI57594C (fi) 1980-09-10

Family

ID=5995427

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773738A FI57594C (fi) 1976-12-14 1977-12-12 Foerfarande foer framstaellning av antiallergiskt verksamma n-(bentstiazol-2-yl)-oxamidsyra-derivat

Country Status (17)

Country Link
JP (1) JPS5377058A (nl)
AR (1) AR216496A1 (nl)
AT (1) AT360523B (nl)
AU (1) AU510730B2 (nl)
BE (1) BE861794A (nl)
CS (1) CS203179B2 (nl)
DD (1) DD133329A5 (nl)
DE (1) DE2656468A1 (nl)
ES (1) ES465034A1 (nl)
FI (1) FI57594C (nl)
FR (1) FR2374317A1 (nl)
GB (1) GB1538822A (nl)
HU (1) HU175340B (nl)
NL (1) NL7713580A (nl)
SE (1) SE7714074L (nl)
SU (1) SU680647A3 (nl)
ZA (1) ZA777236B (nl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2676775A (en) * 1949-10-24 1954-04-27 Gustav O Schulz Electric flatiron cord holder
DE3017976A1 (de) * 1980-05-10 1981-11-19 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte 2-amino-5-halogen-benzothiazole, verfahen zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4321372A (en) 1980-06-16 1982-03-23 Pfizer Inc. Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides
DE3027527A1 (de) 1980-07-19 1982-02-18 Basf Ag, 6700 Ludwigshafen Neue oxamidsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
GB2090826B (en) * 1981-01-09 1985-06-12 Usv Pharma Corp New heterocyclic compounds useful as anti-allergie agents
DE3135250A1 (de) * 1981-09-05 1983-03-17 Basf Ag, 6700 Ludwigshafen Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
FI91859C (fi) * 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
ATE385794T1 (de) 2000-06-21 2008-03-15 Hoffmann La Roche Benzothiazolderivate zur behandlung von alzheimer und parkinson
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
EP1753760B1 (en) 2004-05-24 2008-01-02 F.Hoffmann-La Roche Ag 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
CA2586931C (en) 2004-11-05 2013-08-06 Paul Spurr Process for preparation of isonicotinic acid derivatives
KR100973609B1 (ko) 2005-03-23 2010-08-03 에프. 호프만-라 로슈 아게 mGluR2 길항제로서 아세틸렌일-피라졸로-피리미딘유도체
WO2007039439A1 (en) 2005-09-27 2007-04-12 F.Hoffmann-La Roche Ag Oxadiazolyl pyrazolo-pyrimidines as mglur2 antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150140A (en) * 1976-12-23 1979-04-17 The Upjohn Company Benzothiazolyl oxanic acids, esters and salts

Also Published As

Publication number Publication date
ATA890777A (de) 1980-06-15
ZA777236B (en) 1978-11-29
FI773738A (fi) 1978-06-15
BE861794A (fr) 1978-06-13
AT360523B (de) 1981-01-12
DD133329A5 (de) 1978-12-27
SU680647A3 (ru) 1979-08-15
ES465034A1 (es) 1978-09-01
FI57594B (fi) 1980-05-30
AU3137777A (en) 1979-06-14
JPS5377058A (en) 1978-07-08
DE2656468A1 (de) 1978-06-15
AR216496A1 (es) 1979-12-28
HU175340B (hu) 1980-07-28
CS203179B2 (en) 1981-02-27
GB1538822A (en) 1979-01-24
FR2374317B1 (nl) 1980-11-07
FR2374317A1 (fr) 1978-07-13
SE7714074L (sv) 1978-06-15
AU510730B2 (en) 1980-07-10
NL7713580A (nl) 1978-06-16

Similar Documents

Publication Publication Date Title
FI57594C (fi) Foerfarande foer framstaellning av antiallergiskt verksamma n-(bentstiazol-2-yl)-oxamidsyra-derivat
CA1102802A (en) Benzothiazine derivatives
FI91063B (fi) Menetelmä kinoloniyhdisteiden valmistamiseksi
CZ2000714A3 (cs) 5-Alkyl-2-arylaminofenyloctové kyseliny a jejich deriváty, způsob jejich přípravy a farmaceutické prostředky, které je obsahují
US5223513A (en) Quinoline derivatives, their production and use
US3455924A (en) Dianisylimidazoles
JPH09301958A (ja) 新規ピリミジン化合物及び抗ロタウイルス剤
US4572910A (en) Triazolo[1,5-c]pyrimidines substituted by nitrogen-containing heterocyclic rings
NO794135L (no) Substituerte 4(3h)-kinazolinoner, fremgangsmaate ved fremstilling og anvendelse av disse
JPH0471914B2 (nl)
US3538086A (en) 4-oxo-4h-pyrimido 2,1-b benzothiazoles
OZEKI et al. Studies on antiallergy agents. III. Synthesis of 2-anilino-1, 6-dihydro-6-oxo-5-pyrimidinecarboxylic acids and related compounds
Zinnes et al. 1, 2-Benzothiazines. 6. 3-Carbamoyl-4-hydroxy-2H-1, 2-benzothiazine 1, 1-dioxides as antiinflammatory agents
US3726875A (en) 1,3(2h,4h)-dioxoisoquinoline-4-carboxylate esters and process therefor
EP0102175A1 (en) 5-Oxo-5H-(1)benzopyrano(2,3-b)pyridine derivatives, their production and use
NZ250458A (en) 3-phenyl-benzofuran-2-yl- (and indol-2-yl-) acetamide, -propanamide and -urea derivatives; their preparation, intermediates and pharmaceutical compositions
US4968708A (en) Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same
US3944581A (en) 5-Substituted-2,4-diphenylpyrimidines
FI67706C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara n-5-tetrazolyl)-1-oxo-1h-tiazolo(3,2-a)pyrimidin-2-karboxyl atr
US4254118A (en) 1-Oxo-5H-pyrimido[2,1-c][1,4]benzthiazine-2-carboxylic acid esters
EP0041630B1 (en) New 3h-naphtho(1,2-d)imidazoles, the process for preparing them, the compounds for use as antiinflammatory agents and compositions containing them
US5063229A (en) Imidazolo [1,2-a]pyrimidines and medical use thereof
Bajaj et al. Synthesis and psychotropic evaluation of some new N-substitutedbenzothia/oxazepinylphenothiazines
US3303191A (en) Novel 4-ketodihydro-2, 1-benzothiazine-2, 2-dioxides
JPH04273877A (ja) 新規なイミダゾール誘導体

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: BOEHRINGER MANNHEIM GMBH