FI57261C - Foerfarande foer framstaellning av pao centralnervsystemet verkande n-(heteroaryl-metyl)-6,14-endoeteno/endoetano-7alfa-hydroxylalkyltetrahydronororipavin och -tebain och deras syraadditionssalter - Google Patents
Foerfarande foer framstaellning av pao centralnervsystemet verkande n-(heteroaryl-metyl)-6,14-endoeteno/endoetano-7alfa-hydroxylalkyltetrahydronororipavin och -tebain och deras syraadditionssalter Download PDFInfo
- Publication number
- FI57261C FI57261C FI1989/73A FI198973A FI57261C FI 57261 C FI57261 C FI 57261C FI 1989/73 A FI1989/73 A FI 1989/73A FI 198973 A FI198973 A FI 198973A FI 57261 C FI57261 C FI 57261C
- Authority
- FI
- Finland
- Prior art keywords
- formula
- methyl
- tetrahydro
- compound
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
- C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
- C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2230154A DE2230154A1 (de) | 1972-06-21 | 1972-06-21 | N-(heteroaryl-methyl)-6,14-endoaetheno7alpha-hydroxyalkyl-tetrahydro-nororipavine und -thebaine, deren hydrierungsprodukte und saeureadditionssalze sowie verfahren zu deren herstellung |
DE2230154 | 1972-06-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI57261B FI57261B (fi) | 1980-03-31 |
FI57261C true FI57261C (fi) | 1980-07-10 |
Family
ID=5848276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI1989/73A FI57261C (fi) | 1972-06-21 | 1973-06-20 | Foerfarande foer framstaellning av pao centralnervsystemet verkande n-(heteroaryl-metyl)-6,14-endoeteno/endoetano-7alfa-hydroxylalkyltetrahydronororipavin och -tebain och deras syraadditionssalter |
Country Status (14)
Country | Link |
---|---|
US (1) | US3931189A (da) |
JP (1) | JPS5614673B2 (da) |
AT (7) | AT328101B (da) |
BE (1) | BE801271A (da) |
CH (7) | CH585752A5 (da) |
DE (1) | DE2230154A1 (da) |
DK (1) | DK141629C (da) |
ES (3) | ES416106A1 (da) |
FI (1) | FI57261C (da) |
FR (1) | FR2189066B1 (da) |
GB (1) | GB1431385A (da) |
NL (1) | NL7308555A (da) |
NO (1) | NO139050C (da) |
SE (1) | SE412235B (da) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4232026A (en) * | 1978-07-20 | 1980-11-04 | Merck & Co., Inc. | Diazaditwistanes, and pharmaceutical compositions for treating pain in warm blooded animals containing them |
JPS60119848A (ja) * | 1983-11-30 | 1985-06-27 | 三井建設株式会社 | 繊維補強コンクリ−ト並びにその施工法 |
JPS62298530A (ja) * | 1986-06-16 | 1987-12-25 | Otsuka Pharmaceut Co Ltd | 坐薬用医薬組成物 |
CN1233645C (zh) * | 2001-09-14 | 2005-12-28 | 中国人民解放军军事医学科学院毒物药物研究所 | 新的东罂粟碱衍生物及其医药用途 |
CN1939920B (zh) * | 2005-09-29 | 2011-08-31 | 中国人民解放军军事医学科学院毒物药物研究所 | 东罂粟碱类化合物及其医药用途 |
PL2326651T3 (pl) | 2008-07-30 | 2014-05-30 | Purdue Pharma Lp | Analogi buprenorfiny |
JP2021104932A (ja) * | 2018-03-30 | 2021-07-26 | 日本ケミファ株式会社 | モルヒナン誘導体の製造方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3474101A (en) * | 1960-09-05 | 1969-10-21 | Reckitt & Sons Ltd | Thebaine and oripavine derivatives |
US3285914A (en) * | 1964-06-11 | 1966-11-15 | Smith Kline French Lab | 3-n-substituted derivatives of oripavine and thebaine |
GB1136764A (en) * | 1965-08-13 | 1968-12-18 | Reckitt & Sons Ltd | Derivatives of thebaine and oripavine |
GB1146272A (en) * | 1966-01-17 | 1969-03-26 | Reckitt & Sons Ltd | Novel thebaine and oripavine derivatives |
GB1223445A (en) * | 1968-07-18 | 1971-02-24 | Reckitt & Colmann Prod Ltd | Improvements in or relating to derivatives of morphine, their salts, and processes for their preparation |
DE2107989A1 (de) * | 1971-02-19 | 1972-09-07 | Boehringer Sohn Ingelheim | N-(Furyl-methy])-morphinane, deren Säureadditionssalze sowie Verfahren zu deren Herstellung |
-
1972
- 1972-06-21 DE DE2230154A patent/DE2230154A1/de not_active Withdrawn
-
1973
- 1973-06-06 AT AT462174*7A patent/AT328101B/de not_active IP Right Cessation
- 1973-06-06 AT AT494473A patent/AT325219B/de not_active IP Right Cessation
- 1973-06-06 AT AT461974*7A patent/AT328099B/de not_active IP Right Cessation
- 1973-06-06 AT AT462374*7A patent/AT329198B/de not_active IP Right Cessation
- 1973-06-06 AT AT462074*7A patent/AT328100B/de not_active IP Right Cessation
- 1973-06-06 AT AT461874*7A patent/AT328098B/de not_active IP Right Cessation
- 1973-06-06 AT AT462274*7A patent/AT327409B/de not_active IP Right Cessation
- 1973-06-13 US US05/369,500 patent/US3931189A/en not_active Expired - Lifetime
- 1973-06-18 CH CH1460976A patent/CH585752A5/xx not_active IP Right Cessation
- 1973-06-18 CH CH1461076A patent/CH585753A5/xx not_active IP Right Cessation
- 1973-06-18 CH CH1460876A patent/CH594672A5/xx not_active IP Right Cessation
- 1973-06-18 CH CH1460776A patent/CH586224A5/xx not_active IP Right Cessation
- 1973-06-18 CH CH1461176A patent/CH594673A5/xx not_active IP Right Cessation
- 1973-06-18 CH CH1460676A patent/CH587264A5/xx not_active IP Right Cessation
- 1973-06-18 CH CH881573A patent/CH585751A5/xx not_active IP Right Cessation
- 1973-06-20 SE SE7308709A patent/SE412235B/xx unknown
- 1973-06-20 JP JP6969173A patent/JPS5614673B2/ja not_active Expired
- 1973-06-20 GB GB2934673A patent/GB1431385A/en not_active Expired
- 1973-06-20 DK DK341273A patent/DK141629C/da active
- 1973-06-20 FI FI1989/73A patent/FI57261C/fi active
- 1973-06-20 ES ES416106A patent/ES416106A1/es not_active Expired
- 1973-06-20 NL NL7308555A patent/NL7308555A/xx not_active Application Discontinuation
- 1973-06-20 NO NO2561/73A patent/NO139050C/no unknown
- 1973-06-21 FR FR7322738A patent/FR2189066B1/fr not_active Expired
- 1973-06-21 BE BE132576A patent/BE801271A/xx unknown
-
1974
- 1974-04-05 ES ES425015A patent/ES425015A1/es not_active Expired
- 1974-04-05 ES ES425010A patent/ES425010A1/es not_active Expired
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6306852B1 (en) | Indole derivatives useful as endothelin receptor antagonists | |
Daidone et al. | Synthesis and pharmacological study of ethyl 1-methyl-5-[2-substituted-4-oxo-3 (4H)-quinazolinyl]-1H-pyrazole-4-acetates | |
FI57261C (fi) | Foerfarande foer framstaellning av pao centralnervsystemet verkande n-(heteroaryl-metyl)-6,14-endoeteno/endoetano-7alfa-hydroxylalkyltetrahydronororipavin och -tebain och deras syraadditionssalter | |
JP2740250B2 (ja) | ヘテラ―脂肪族カルボクサミド誘導体、その製造方法、該化合物の中間体および該化合物を含有するロイコトリエン拮抗作用を有する薬学的組成物 | |
Aotsuka et al. | Novel and potent aldose reductase inhibitors: 4-benzyl-and 4-(benzothiazol-2-ylmethyl)-3, 4-dihydro-3-oxo-2H-1, 4-benzothiazine-2-acetic acid derivatives | |
US4659731A (en) | 2-(4,5-Dihydro-1H-imidazol-2-yl)-2,3-dihydroindole derivatives and their application as α2 receptor antagonist or α1 receptor agonists | |
US3015661A (en) | Decahydroisoquinoline derivatives | |
EP3619199B1 (en) | Preparation of 2-([1,2,3]triazol-2-yl)-benzoic acid derivatives | |
US3944581A (en) | 5-Substituted-2,4-diphenylpyrimidines | |
JPS5823398B2 (ja) | ピペリジルベンゾイミダゾ−ルユウドウタイノセイゾウホウ | |
HU192416B (en) | Process for preparing indole derivatives and pharmaceutical compositions containing sucg compounds | |
Demopoulos et al. | Synthesis of 6, 7, 8, 9‐tetrahydro‐N, N‐di‐n‐propyl‐1H‐benz [g] indol‐7‐amine, a potential dopamine receptor agonist | |
Stillings et al. | Substituted 5H-dibenz [b, g]-1, 4-oxazocines and related amino acids with antiinflammatory activity | |
US4022780A (en) | Process for the manufacture of indole derivatives | |
Katritzky et al. | Syntheses of triazolo [6, 7‐d] phthalide and triazolo [6, 7‐d] dihydrocoumarin | |
Tshiluka et al. | Synthesis of some new 5-arylidene-2, 4-thiazolidinedione esters | |
Gunkara et al. | Synthesis of New N-Phthalimide Substituted Tricyclic Imide Containing Isoxazoline and Bispiro Functional Group as Possible Anti-cancer Agents | |
NO137998B (no) | Analogifremgangsm}te for fremstilling av terapeutisk aktive tebain- og oripavin-derivater | |
AU781663B2 (en) | New pyrimidin-4-one compounds, a process for their preparation and pharmaceutical compositions containing them | |
KATO et al. | Studies on Ketene and Its Derivatives. LXXIX. Reaction of Diketene with Benzimidazole and 2-Methylbenzimidazole Derivatives | |
IT9020092A1 (it) | Procedimento per la preparazione di derivati chinazolinici | |
Tsuge et al. | Studies of polyazapentalenes. II. The preparation of 1, 3a, 6a-triazapentalenes | |
US5229408A (en) | 4-carbamoyl-1,2-dihydro-3H-indazol-3-one derivatives | |
US3314951A (en) | Spiro(indoline-3, 2'-[2h-1, 3]thiazin)-2-ones and derivatives thereof | |
Chaudhari et al. | Pelagia Research Library |