FI3811967T3 - Biologisesti aktiivisten kompleksien valmistus - Google Patents
Biologisesti aktiivisten kompleksien valmistus Download PDFInfo
- Publication number
- FI3811967T3 FI3811967T3 FIEP20208669.0T FI20208669T FI3811967T3 FI 3811967 T3 FI3811967 T3 FI 3811967T3 FI 20208669 T FI20208669 T FI 20208669T FI 3811967 T3 FI3811967 T3 FI 3811967T3
- Authority
- FI
- Finland
- Prior art keywords
- salt
- polypeptide
- alpha
- lactalbumin
- seq
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Water Supply & Treatment (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Enzymes And Modification Thereof (AREA)
- Inorganic Chemistry (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1707715.7A GB201707715D0 (en) | 2017-05-14 | 2017-05-14 | Preperation of biologically active complexes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3811967T3 true FI3811967T3 (fi) | 2023-12-28 |
Family
ID=59201543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP20208669.0T FI3811967T3 (fi) | 2017-05-14 | 2018-05-14 | Biologisesti aktiivisten kompleksien valmistus |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20200140481A1 (https=) |
| EP (2) | EP3811967B1 (https=) |
| JP (2) | JP7672122B2 (https=) |
| KR (2) | KR20200015557A (https=) |
| CN (2) | CN119700935A (https=) |
| AU (1) | AU2018269304B2 (https=) |
| CA (1) | CA3063285A1 (https=) |
| DK (2) | DK3618848T3 (https=) |
| ES (2) | ES2861252T3 (https=) |
| FI (1) | FI3811967T3 (https=) |
| GB (1) | GB201707715D0 (https=) |
| PL (2) | PL3618848T3 (https=) |
| WO (1) | WO2018210759A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201621752D0 (en) * | 2016-12-20 | 2017-02-01 | Hamlet Pharma Ab | Therapeutically active complexes |
| GB201707715D0 (en) * | 2017-05-14 | 2017-06-28 | Hamlet Pharma Ab | Preperation of biologically active complexes |
| GB2574845A (en) * | 2018-06-20 | 2019-12-25 | Hamlet Pharma Ab | Therapeutically active complexes |
| WO2019243547A1 (en) * | 2018-06-20 | 2019-12-26 | Hamlet Pharma Ab | Therapeutically active complexes |
| WO2021032807A1 (en) * | 2019-08-20 | 2021-02-25 | Hamlet Pharma Ab | Combination of a chemotherapeutic agent and alpha-lactoglubulin-oleic acid complex for cancer therapy |
| GB202015836D0 (en) * | 2020-10-06 | 2020-11-18 | Hamlet Pharma Ab | Compositions |
| US20260108588A1 (en) | 2022-10-03 | 2026-04-23 | Linnane Pharma Ab | A complex comprising a alpha-lactalbumin and a fatty acid or lipid for use in the treatment or prevention of cancer |
| GB202303177D0 (en) | 2023-03-03 | 2023-04-19 | Linnane Pharma Ab | Method of predicting response to treatment |
| WO2025186107A1 (en) | 2024-03-04 | 2025-09-12 | Linnane Pharma Ab | Therapy |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1871252A (zh) * | 2003-09-05 | 2006-11-29 | Gtc生物治疗学公司 | 在转基因哺乳动物奶中生产融合蛋白的方法 |
| US8796218B2 (en) | 2009-01-09 | 2014-08-05 | Hamlet Pharma Ab | Complex and production process |
| WO2010131237A1 (en) | 2009-05-13 | 2010-11-18 | Agriculture And Food Development Authority (Teagasc) | A process for producing a biologically active globular protein complex |
| GB0908279D0 (en) | 2009-05-14 | 2009-06-24 | Enovate Systems Ltd | Subsea winch |
| ES2613986T3 (es) * | 2010-11-24 | 2017-05-29 | Hamlet Pharma Ab | Complejo biológicamente activo y su preparación |
| HUE038910T2 (hu) * | 2012-08-09 | 2018-12-28 | Hamlet Pharma Ab | Profilaktikus és gyógytáp terápia |
| GB201621752D0 (en) * | 2016-12-20 | 2017-02-01 | Hamlet Pharma Ab | Therapeutically active complexes |
| GB201707715D0 (en) * | 2017-05-14 | 2017-06-28 | Hamlet Pharma Ab | Preperation of biologically active complexes |
-
2017
- 2017-05-14 GB GBGB1707715.7A patent/GB201707715D0/en not_active Ceased
-
2018
- 2018-05-14 AU AU2018269304A patent/AU2018269304B2/en active Active
- 2018-05-14 ES ES18729327T patent/ES2861252T3/es active Active
- 2018-05-14 EP EP20208669.0A patent/EP3811967B1/en active Active
- 2018-05-14 JP JP2019563219A patent/JP7672122B2/ja active Active
- 2018-05-14 ES ES20208669T patent/ES2973290T3/es active Active
- 2018-05-14 FI FIEP20208669.0T patent/FI3811967T3/fi active
- 2018-05-14 CN CN202411849059.8A patent/CN119700935A/zh active Pending
- 2018-05-14 KR KR1020197037015A patent/KR20200015557A/ko not_active Ceased
- 2018-05-14 CA CA3063285A patent/CA3063285A1/en active Pending
- 2018-05-14 US US16/612,272 patent/US20200140481A1/en not_active Abandoned
- 2018-05-14 DK DK18729327.9T patent/DK3618848T3/da active
- 2018-05-14 CN CN201880032057.6A patent/CN110650746B/zh active Active
- 2018-05-14 KR KR1020267002686A patent/KR20260021814A/ko active Pending
- 2018-05-14 PL PL18729327T patent/PL3618848T3/pl unknown
- 2018-05-14 EP EP18729327.9A patent/EP3618848B1/en active Active
- 2018-05-14 PL PL20208669.0T patent/PL3811967T3/pl unknown
- 2018-05-14 WO PCT/EP2018/062396 patent/WO2018210759A1/en not_active Ceased
- 2018-05-14 DK DK20208669.0T patent/DK3811967T5/da active
-
2021
- 2021-01-12 US US17/146,588 patent/US12331073B2/en active Active
-
2023
- 2023-03-15 JP JP2023040807A patent/JP7705160B2/ja active Active
-
2025
- 2025-05-12 US US19/205,790 patent/US20260085088A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2973290T3 (es) | 2024-06-19 |
| AU2018269304A1 (en) | 2019-11-21 |
| DK3811967T5 (da) | 2024-08-19 |
| EP3811967A1 (en) | 2021-04-28 |
| US12331073B2 (en) | 2025-06-17 |
| CN119700935A (zh) | 2025-03-28 |
| KR20260021814A (ko) | 2026-02-13 |
| PL3811967T3 (pl) | 2024-03-18 |
| EP3618848B1 (en) | 2020-11-25 |
| DK3618848T3 (da) | 2021-03-01 |
| KR20200015557A (ko) | 2020-02-12 |
| GB201707715D0 (en) | 2017-06-28 |
| JP7672122B2 (ja) | 2025-05-07 |
| CA3063285A1 (en) | 2018-11-22 |
| EP3811967B1 (en) | 2023-12-20 |
| JP2023075290A (ja) | 2023-05-30 |
| US20260085088A1 (en) | 2026-03-26 |
| JP7705160B2 (ja) | 2025-07-09 |
| ES2861252T3 (es) | 2021-10-06 |
| JP2020519673A (ja) | 2020-07-02 |
| US20200140481A1 (en) | 2020-05-07 |
| CN110650746A (zh) | 2020-01-03 |
| CN110650746B (zh) | 2024-12-31 |
| WO2018210759A1 (en) | 2018-11-22 |
| US20210130394A1 (en) | 2021-05-06 |
| PL3618848T3 (pl) | 2021-06-14 |
| AU2018269304B2 (en) | 2025-02-27 |
| DK3811967T3 (da) | 2024-01-08 |
| EP3618848A1 (en) | 2020-03-11 |
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