FI3777833T3 - Dopa-dekarboksylaasin estäjän koostumuksia - Google Patents

Dopa-dekarboksylaasin estäjän koostumuksia Download PDF

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Publication number
FI3777833T3
FI3777833T3 FIEP20198371.5T FI20198371T FI3777833T3 FI 3777833 T3 FI3777833 T3 FI 3777833T3 FI 20198371 T FI20198371 T FI 20198371T FI 3777833 T3 FI3777833 T3 FI 3777833T3
Authority
FI
Finland
Prior art keywords
weight
carbidopa
levodopa
cysteine
salt
Prior art date
Application number
FIEP20198371.5T
Other languages
English (en)
Finnish (fi)
Inventor
Oron Yacoby-Zeevi
Original Assignee
Neuroderm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53488380&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI3777833(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neuroderm Ltd filed Critical Neuroderm Ltd
Application granted granted Critical
Publication of FI3777833T3 publication Critical patent/FI3777833T3/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FIEP20198371.5T 2014-03-13 2015-03-12 Dopa-dekarboksylaasin estäjän koostumuksia FI3777833T3 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461952477P 2014-03-13 2014-03-13
US201461990967P 2014-05-09 2014-05-09

Publications (1)

Publication Number Publication Date
FI3777833T3 true FI3777833T3 (fi) 2024-01-03

Family

ID=53488380

Family Applications (1)

Application Number Title Priority Date Filing Date
FIEP20198371.5T FI3777833T3 (fi) 2014-03-13 2015-03-12 Dopa-dekarboksylaasin estäjän koostumuksia

Country Status (19)

Country Link
US (5) US10022320B2 (enExample)
EP (3) EP3116475B1 (enExample)
JP (2) JP6591995B2 (enExample)
CN (1) CN106413754B (enExample)
AU (1) AU2015228369B2 (enExample)
BR (1) BR112016021034A8 (enExample)
CA (1) CA2942244C (enExample)
DK (2) DK3116475T3 (enExample)
ES (2) ES2967693T3 (enExample)
FI (1) FI3777833T3 (enExample)
HR (2) HRP20201948T1 (enExample)
HU (2) HUE064818T2 (enExample)
IL (1) IL247668B (enExample)
MX (1) MX2016011837A (enExample)
PL (2) PL3777833T3 (enExample)
PT (2) PT3777833T (enExample)
RS (1) RS65060B1 (enExample)
RU (1) RU2684105C2 (enExample)
WO (1) WO2015136538A1 (enExample)

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PT3192500T (pt) 2009-05-19 2021-01-05 Neuroderm Ltd Composições para a administração contínua de inibidores da dopa decarboxilase
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US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
PL3777833T3 (pl) 2014-03-13 2024-03-25 Neuroderm Ltd. Kompozycje inhibitorów dekarboksylazy dopa
JP6415715B2 (ja) 2015-09-30 2018-10-31 デューク・ユニヴァーシティ アスコルベート製剤及び造影剤としての使用方法
WO2018154447A1 (en) * 2017-02-21 2018-08-30 Neuroderm Ltd Dopa decarboxylase inhibitor compositions
TW202031265A (zh) 2018-11-15 2020-09-01 美商艾伯維有限公司 用於皮下投藥之醫藥調配物
WO2020178810A1 (en) * 2019-03-04 2020-09-10 Neuroderm, Ltd. Pharmaceutical compositions comprising levodopa amide derivatives and uses thereof
CN111701024B (zh) * 2020-05-26 2022-05-24 上海京新生物医药有限公司 一种左旋多巴制剂及其制备方法及其应用
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
CN113396897B (zh) * 2021-07-26 2022-06-07 苏州华测生物技术有限公司 一种稳定生物基质中卡比多巴/左旋多巴的方法
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Also Published As

Publication number Publication date
MX2016011837A (es) 2017-04-27
EP4299128A3 (en) 2024-04-17
ES2967693T3 (es) 2024-05-03
DK3777833T3 (da) 2023-12-18
PT3777833T (pt) 2024-01-09
JP6770158B2 (ja) 2020-10-14
WO2015136538A1 (en) 2015-09-17
EP3777833A1 (en) 2021-02-17
EP3116475A1 (en) 2017-01-18
DK3116475T3 (da) 2020-12-07
ES2836325T3 (es) 2021-06-24
JP2020011977A (ja) 2020-01-23
RU2016135952A3 (enExample) 2018-09-12
EP3116475B1 (en) 2020-11-04
AU2015228369A1 (en) 2016-10-27
US20150352212A1 (en) 2015-12-10
US10624839B2 (en) 2020-04-21
PL3777833T3 (pl) 2024-03-25
RU2684105C2 (ru) 2019-04-04
IL247668B (en) 2020-09-30
CA2942244A1 (en) 2015-09-17
CA2942244C (en) 2022-08-23
US20210038505A1 (en) 2021-02-11
HUE052642T2 (hu) 2021-05-28
EP3777833B1 (en) 2023-10-18
AU2015228369B2 (en) 2020-05-21
US20260102334A1 (en) 2026-04-16
HUE064818T2 (hu) 2024-04-28
PL3116475T3 (pl) 2021-02-08
HRP20231716T1 (hr) 2024-03-15
BR112016021034A8 (pt) 2021-06-29
US20230240980A1 (en) 2023-08-03
CN106413754B (zh) 2019-11-29
PT3116475T (pt) 2020-12-15
RS65060B1 (sr) 2024-02-29
IL247668A0 (en) 2016-11-30
US20190151233A1 (en) 2019-05-23
EP4299128A2 (en) 2024-01-03
JP6591995B2 (ja) 2019-10-16
CN106413754A (zh) 2017-02-15
JP2017507973A (ja) 2017-03-23
US10022320B2 (en) 2018-07-17
BR112016021034A2 (pt) 2017-08-15
RU2016135952A (ru) 2018-04-13
HRP20201948T1 (hr) 2021-01-22

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