HUE052642T2 - DOPA dekarboxiláz inhibitor készítmények - Google Patents
DOPA dekarboxiláz inhibitor készítményekInfo
- Publication number
- HUE052642T2 HUE052642T2 HUE15731727A HUE15731727A HUE052642T2 HU E052642 T2 HUE052642 T2 HU E052642T2 HU E15731727 A HUE15731727 A HU E15731727A HU E15731727 A HUE15731727 A HU E15731727A HU E052642 T2 HUE052642 T2 HU E052642T2
- Authority
- HU
- Hungary
- Prior art keywords
- decarboxylase inhibitor
- inhibitor compositions
- dopa decarboxylase
- dopa
- compositions
- Prior art date
Links
- 229940081615 DOPA decarboxylase inhibitor Drugs 0.000 title 1
- 239000000534 dopa decarboxylase inhibitor Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461952477P | 2014-03-13 | 2014-03-13 | |
US201461990967P | 2014-05-09 | 2014-05-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE052642T2 true HUE052642T2 (hu) | 2021-05-28 |
Family
ID=53488380
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE20198371A HUE064818T2 (hu) | 2014-03-13 | 2015-03-12 | Dopa dekarboxiláz inhibitor készítmények |
HUE15731727A HUE052642T2 (hu) | 2014-03-13 | 2015-03-12 | DOPA dekarboxiláz inhibitor készítmények |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE20198371A HUE064818T2 (hu) | 2014-03-13 | 2015-03-12 | Dopa dekarboxiláz inhibitor készítmények |
Country Status (19)
Country | Link |
---|---|
US (4) | US10022320B2 (hu) |
EP (3) | EP3116475B1 (hu) |
JP (2) | JP6591995B2 (hu) |
CN (1) | CN106413754B (hu) |
AU (1) | AU2015228369B2 (hu) |
BR (1) | BR112016021034A8 (hu) |
CA (1) | CA2942244C (hu) |
DK (2) | DK3777833T3 (hu) |
ES (2) | ES2967693T3 (hu) |
FI (1) | FI3777833T3 (hu) |
HR (2) | HRP20231716T1 (hu) |
HU (2) | HUE064818T2 (hu) |
IL (1) | IL247668B (hu) |
MX (1) | MX2016011837A (hu) |
PL (2) | PL3116475T3 (hu) |
PT (2) | PT3116475T (hu) |
RS (1) | RS65060B1 (hu) |
RU (1) | RU2684105C2 (hu) |
WO (1) | WO2015136538A1 (hu) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2840748T3 (es) | 2009-05-19 | 2021-07-07 | Neuroderm Ltd | Composiciones para la administración continua de inhibidores de dopa decarboxilasa |
MX348225B (es) | 2010-11-15 | 2017-05-31 | Neuroderm Ltd | Administracion continua de levodopa, inhibidores de dopa decarboxilasa, inhibidores de catecol-o-metil transferasa y composiciones para la misma. |
PT3116475T (pt) | 2014-03-13 | 2020-12-15 | Neuroderm Ltd | Composições de inibidores de dopa-descarboxilase |
US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
CN106999613B (zh) | 2015-09-30 | 2020-11-17 | 杜克大学 | 作为造影剂的抗坏血酸制剂和使用方法 |
WO2018154447A1 (en) * | 2017-02-21 | 2018-08-30 | Neuroderm Ltd | Dopa decarboxylase inhibitor compositions |
CN113015531A (zh) | 2018-11-15 | 2021-06-22 | 艾伯维公司 | 用于皮下施用的药物调配物 |
WO2020178810A1 (en) * | 2019-03-04 | 2020-09-10 | Neuroderm, Ltd. | Pharmaceutical compositions comprising levodopa amide derivatives and uses thereof |
CN111701024B (zh) * | 2020-05-26 | 2022-05-24 | 上海京新生物医药有限公司 | 一种左旋多巴制剂及其制备方法及其应用 |
US11213502B1 (en) | 2020-11-17 | 2022-01-04 | Neuroderm, Ltd. | Method for treatment of parkinson's disease |
US11331293B1 (en) | 2020-11-17 | 2022-05-17 | Neuroderm, Ltd. | Method for treatment of Parkinson's disease |
US11844754B2 (en) | 2020-11-17 | 2023-12-19 | Neuroderm, Ltd. | Methods for treatment of Parkinson's disease |
CN113396897B (zh) * | 2021-07-26 | 2022-06-07 | 苏州华测生物技术有限公司 | 一种稳定生物基质中卡比多巴/左旋多巴的方法 |
Family Cites Families (91)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3769424A (en) | 1970-10-01 | 1973-10-30 | Merck & Co Inc | Composition and method of treating dopamine deficiency in brain tissue |
AU6889274A (en) | 1973-05-17 | 1975-11-20 | Astra Laekemedel Ab | Treatment of neurological disorders |
US3936495A (en) | 1973-11-27 | 1976-02-03 | Merck & Co., Inc. | Purification process |
US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
US4241082A (en) | 1977-09-02 | 1980-12-23 | Sankyo Company Limited | Agents for promoting reproductive ability of domestic animals |
JPS5450700A (en) | 1977-09-28 | 1979-04-20 | Sankyo Co | Glazing agent of animal leather |
JPS6021570B2 (ja) | 1978-07-04 | 1985-05-28 | 三共株式会社 | ド−パ類の高濃度製剤の製法 |
JPS56115749A (en) | 1980-02-18 | 1981-09-11 | Sagami Chem Res Center | Dopa derivative |
US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
US4642316A (en) | 1985-05-20 | 1987-02-10 | Warner-Lambert Company | Parenteral phenytoin preparations |
ES2042520T3 (es) | 1986-06-10 | 1993-12-16 | Chiesi Farma Spa | Composiciones farmaceuticas que contienen el ester metilico de levodopa, preparacion y aplicaciones terapeuticas del mismo. |
US4832957A (en) | 1987-12-11 | 1989-05-23 | Merck & Co., Inc. | Controlled release combination of carbidopa/levodopa |
US4684666A (en) | 1986-08-19 | 1987-08-04 | Haas Pharmaceuticals, Inc. | Stabilized liquid analgesic compositions |
IT1226902B (it) | 1988-07-12 | 1991-02-21 | Mini Ricerca Scient Tecnolog | Processo per la sintesi del levodopa |
US4963568A (en) | 1989-05-31 | 1990-10-16 | Abbott Laboratories | Dopamine agonists |
US5350769A (en) | 1990-10-30 | 1994-09-27 | Ss Pharmaceutical Co., Ltd. | Antiinflammatory gel preparation |
US5877176A (en) | 1991-12-26 | 1999-03-02 | Cornell Research Foundation, Inc. | Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis |
CA2143070C (en) | 1994-02-22 | 2001-12-18 | Pankaj Modi | Oral controlled release liquid suspension pharmaceutical formulation |
JPH11505828A (ja) | 1995-05-26 | 1999-05-25 | ファイザー・インコーポレーテッド | パーキンソン症候群の治療用の選択的nmdaアンタゴニスト含有組合せ |
GB9523833D0 (en) | 1995-11-22 | 1996-01-24 | Boots Co Plc | Medical treatment |
US6746688B1 (en) | 1996-10-13 | 2004-06-08 | Neuroderm Ltd. | Apparatus for the transdermal treatment of Parkinson's disease |
IL119417A (en) | 1996-10-13 | 2003-02-12 | Moshe Kushnir | Pharmaceutical composition for transdermal administration of levodopa for parkinson's disease |
US5861423A (en) | 1997-02-21 | 1999-01-19 | Caldwell; William Scott | Pharmaceutical compositions incorporating aryl substituted olefinic amine compounds |
AU1917899A (en) | 1998-03-20 | 1999-10-18 | Warner-Lambert Company | Crystalline sodium phenytoin monohydrate |
US7201923B1 (en) | 1998-03-23 | 2007-04-10 | General Mills, Inc. | Encapsulation of sensitive liquid components into a matrix to obtain discrete shelf-stable particles |
CA2327285C (en) | 1998-05-15 | 2005-06-14 | Warner-Lambert Company | Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same |
US6274168B1 (en) | 1999-02-23 | 2001-08-14 | Mylan Pharmaceuticals Inc. | Phenytoin sodium pharmaceutical compositions |
US6716452B1 (en) | 2000-08-22 | 2004-04-06 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
WO2000054773A1 (en) | 1999-03-12 | 2000-09-21 | Nitromed, Inc. | Dopamine agonists in combination with nitric oxide donors, compositions and methods of use |
FI109453B (fi) | 1999-06-30 | 2002-08-15 | Orion Yhtymae Oyj | Farmaseuttinen koostumus |
US7479498B2 (en) | 1999-08-23 | 2009-01-20 | Phoenix Biosciences, Inc. | Treatments for viral infections |
US6348965B1 (en) | 1999-09-24 | 2002-02-19 | Henry Palladino | Solid state fluorescence and absorption spectroscopy |
SE0001151D0 (sv) | 2000-03-31 | 2000-03-31 | Amarin Dev Ab | Method for producing a controlled-release composition |
US20020028799A1 (en) | 2000-07-06 | 2002-03-07 | Naylor Alasdair Mark | Treatment of male sexual dysfunction |
GB0017387D0 (en) | 2000-07-14 | 2000-08-30 | Pfizer Ltd | Novel enzyme |
US20020099013A1 (en) | 2000-11-14 | 2002-07-25 | Thomas Piccariello | Active agent delivery systems and methods for protecting and administering active agents |
US20030119714A1 (en) | 2000-12-15 | 2003-06-26 | Naylor Alasdair Mark | Treatment of male sexual dysfunction |
US6989385B2 (en) | 2000-12-21 | 2006-01-24 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
IL159812A0 (en) | 2001-07-12 | 2004-06-20 | Teva Pharma | Dual release formulation comprising levodopa ethyl ester and a decarboxylase inhibitor in immediate release layer with levodopa ethyl ester in a controlled release core |
AU2002335077B2 (en) | 2001-10-19 | 2006-09-07 | Idexx Laboratories, Inc. | Injectable compositions for the controlled delivery of pharmacologically active compound |
WO2003050261A2 (en) | 2001-12-10 | 2003-06-19 | Bristol-Myers Squibb Company | (1-phenyl-2-heteroaryl)ethyl-guanidine compounds as inhibitors of mitochondrial f1f0 atp hydrolase |
ES2189682B1 (es) | 2001-12-11 | 2004-04-01 | Laboratorios Del Dr. Esteve, S.A. | Preparacion bebible que comprende ketoprofeno y su empleo en el tratamiento de procesos que cursan con fiebre, inflamacion y/o dolor, en un colectivo de animales, de forma simultanea. |
EP1496868A1 (en) | 2002-04-11 | 2005-01-19 | Ranbaxy Laboratories, Ltd. | Controlled release pharmaceutical compositions of carbidopa and levodopa |
US7985422B2 (en) | 2002-08-05 | 2011-07-26 | Torrent Pharmaceuticals Limited | Dosage form |
DE50312598D1 (de) | 2002-10-10 | 2010-05-20 | Morphochem Ag Komb Chemie | Neue verbindungen mit antibakterieller aktivität |
WO2004069146A2 (en) | 2003-02-07 | 2004-08-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | L-dopa amide derivatives and uses thereof |
KR101137785B1 (ko) | 2003-07-18 | 2012-04-25 | 백스터 인터내셔널 인코포레이티드 | 제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물 |
US7589233B2 (en) | 2003-07-29 | 2009-09-15 | Signature R&D Holdings, Llc | L-Threonine derivatives of high therapeutic index |
US8173840B2 (en) | 2003-07-29 | 2012-05-08 | Signature R&D Holdings, Llc | Compounds with high therapeutic index |
GB0319935D0 (en) | 2003-08-26 | 2003-09-24 | Cipla Ltd | Polymorphs |
CN1845728B (zh) * | 2003-08-29 | 2013-06-19 | 转化医药公司 | 包含左旋多巴和卡比多巴的药物组合物 |
MXPA06002344A (es) * | 2003-08-29 | 2006-05-19 | Transform Pharmaceuticals Inc | Composiciones farmaceuticas y metodo para usar levodopa y carbidopa. |
US20050053669A1 (en) | 2003-09-05 | 2005-03-10 | Boehringer Ingelheim International Gmbh | Administration form for the oral application of poorly soluble acidic and amphorteric drugs |
US20050163841A1 (en) | 2003-10-31 | 2005-07-28 | Wong Patrick S. | Compositions and dosage forms for enhanced absorption of 3-amino-n-butyl-phosphinic acid |
WO2005099678A1 (en) | 2004-04-06 | 2005-10-27 | Transform Pharmaceuticals, Inc. | Pharmaceutical compositions and method of using levodopa and carbidopa |
SE0401842D0 (sv) | 2004-07-12 | 2004-07-12 | Dizlin Medical Design Ab | Infusion and injection solution of levodopa |
WO2006029411A2 (en) | 2004-09-09 | 2006-03-16 | Yeda Research And Development Co. Ltd. | Mixtures of polypeptides, compositions containing and processes for preparing same, and uses thereof |
WO2006037061A2 (en) | 2004-09-28 | 2006-04-06 | Farouk Karoum | Compositions and methods of using d-dopa to treat parkinson's disease |
CA2582346A1 (en) | 2004-10-01 | 2006-04-13 | The Research Foundation Of State University Of New York | Morphine and morphine precursors |
CA2611114C (en) | 2005-06-08 | 2014-09-23 | Orion Corporation | An entacapone-containing oral dosage form |
DE102006021872B4 (de) | 2006-05-11 | 2008-04-17 | Sanofi-Aventis | 4,5-Diphenyl-pyrimidinyl-oxy oder -mercapto substituierte Carbonsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
MX2008015339A (es) | 2006-05-31 | 2008-12-16 | Solvay Pharm Gmbh | Administracion intestinal a largo plazo durante 24 horas de levodopa/carbidopa. |
AR062659A1 (es) | 2006-09-08 | 2008-11-26 | Drug Tech Corp | Composicion de liberacion sostenida de levodopa y metodo para su uso |
CA2606658A1 (en) | 2006-10-13 | 2008-04-13 | Mike Tyers | Compositions and methods for treating neurological disorders or damage |
JP5631734B2 (ja) | 2007-04-06 | 2014-11-26 | トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド | 流体薬物を供給するためのシステム及び方法 |
CL2008003507A1 (es) | 2007-11-26 | 2009-11-27 | Neuroderm Ltd | Composicion farmaceutica que comprende nicotina y un inhibidor de la desensibilizacion del receptor de acetilcolina nicotinico (nachr) opipramol; kit farmaceutico; dispositivo medico; y uso para tratar una enfermedad o trastorno del sistema nervioso central o periferico. |
PT2252284E (pt) * | 2008-02-06 | 2011-08-23 | Wockhardt Research Center | COMPOSIÇÕES FARMACjUTICAS DE ENTACAPONE, LEVODOPA E CARBIDOPA COM BIODISPONIBILIDADE MELHORADA |
CN101669925B (zh) | 2008-09-10 | 2011-08-10 | 天津药物研究院 | 干粉吸入剂、其制备方法和用途 |
WO2010055133A1 (en) | 2008-11-14 | 2010-05-20 | Neurosearch A/S | Benzimidazole derivatives and their use for modulating the gabaa receptor complex |
US20130253056A1 (en) | 2009-05-19 | 2013-09-26 | Neuroderm, Ltd. | Continuous Administration of Levodopa and/or Dopa Decarboxylase Inhibitors and Compositions for Same |
ES2840748T3 (es) | 2009-05-19 | 2021-07-07 | Neuroderm Ltd | Composiciones para la administración continua de inhibidores de dopa decarboxilasa |
CN101987081B (zh) | 2010-07-16 | 2012-08-08 | 钟术光 | 一种控释制剂 |
KR101187064B1 (ko) | 2010-07-18 | 2012-09-28 | 주식회사 바이오폴리메드 | 양이온성 지질, 이의 제조 방법 및 이를 포함하는 세포내 이행성을 갖는 전달체 |
US10150792B2 (en) | 2010-11-08 | 2018-12-11 | Synthonics, Inc. | Bismuth-containing compounds, coordination polymers, methods for modulating pharmacokinetic properties of biologically active agents, and methods for treating patients |
MX348225B (es) * | 2010-11-15 | 2017-05-31 | Neuroderm Ltd | Administracion continua de levodopa, inhibidores de dopa decarboxilasa, inhibidores de catecol-o-metil transferasa y composiciones para la misma. |
LT2640370T (lt) | 2010-11-15 | 2018-09-10 | Neuroderm Ltd | Kompozicijos, skirtos aktyvių agentų įvedimui po oda |
BR112013014304A2 (pt) | 2010-12-10 | 2016-07-19 | Synagile Corp | composições de pró-fármaco levodopa infundíveis subcutaneamente e método de infusão |
WO2013061161A2 (en) | 2011-10-28 | 2013-05-02 | Green Bcn Consulting Services Sl | New combination therapies for treating neurological disorders |
TR201204839A2 (tr) * | 2012-04-25 | 2012-12-21 | Ali̇ Rai̇f İlaç Sanayi̇ A.Ş. | Uzatılmış salım sağlayan levodopa karbıdopa entakapon içeren tablet formülasyonu. |
US20150217046A1 (en) | 2012-06-05 | 2015-08-06 | Synagile Corporation | Dosing regimens for subcutaneously infusible acidic compositions |
CN107693486A (zh) | 2012-06-05 | 2018-02-16 | 纽罗德姆有限公司 | 包含阿朴吗啡和有机酸的组合物及其用途 |
SG10201911731YA (en) * | 2013-03-13 | 2020-02-27 | Neuroderm Ltd | Method for treatment of parkinson's disease |
US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
PT3116475T (pt) | 2014-03-13 | 2020-12-15 | Neuroderm Ltd | Composições de inibidores de dopa-descarboxilase |
AR102389A1 (es) | 2014-10-21 | 2017-02-22 | Abbvie Inc | Profármacos de carbidopa y l-dopa y métodos de uso de los mismos, kit |
BR112018010564A2 (pt) | 2015-11-24 | 2018-11-21 | Neuroderm Ltd. | composições farmacêuticas compreendendo levodopa amida e usos das mesmas |
WO2018154447A1 (en) | 2017-02-21 | 2018-08-30 | Neuroderm Ltd | Dopa decarboxylase inhibitor compositions |
AR112473A1 (es) | 2017-08-21 | 2019-10-30 | Neuroderm Ltd | Proceso para preparar amida de levodopa purificada |
WO2019038639A1 (en) | 2017-08-21 | 2019-02-28 | Neuroderm Ltd | FREE LEOPODOPA CRYSTALLINE AMIDE BASE AND METHODS OF MAKING AND USING SAME |
AR112472A1 (es) | 2017-08-21 | 2019-10-30 | Neuroderm Ltd | Forma de sales cristalinas de amida de levodopa y métodos para elaborarlas y usarlas |
-
2015
- 2015-03-12 PT PT157317272T patent/PT3116475T/pt unknown
- 2015-03-12 WO PCT/IL2015/050258 patent/WO2015136538A1/en active Application Filing
- 2015-03-12 MX MX2016011837A patent/MX2016011837A/es active IP Right Grant
- 2015-03-12 ES ES20198371T patent/ES2967693T3/es active Active
- 2015-03-12 PL PL15731727T patent/PL3116475T3/pl unknown
- 2015-03-12 RU RU2016135952A patent/RU2684105C2/ru active
- 2015-03-12 FI FIEP20198371.5T patent/FI3777833T3/fi active
- 2015-03-12 AU AU2015228369A patent/AU2015228369B2/en active Active
- 2015-03-12 PT PT201983715T patent/PT3777833T/pt unknown
- 2015-03-12 EP EP15731727.2A patent/EP3116475B1/en active Active
- 2015-03-12 EP EP23204007.1A patent/EP4299128A3/en active Pending
- 2015-03-12 US US14/645,848 patent/US10022320B2/en active Active
- 2015-03-12 JP JP2016556969A patent/JP6591995B2/ja active Active
- 2015-03-12 ES ES15731727T patent/ES2836325T3/es active Active
- 2015-03-12 CN CN201580024073.7A patent/CN106413754B/zh active Active
- 2015-03-12 RS RS20240006A patent/RS65060B1/sr unknown
- 2015-03-12 BR BR112016021034A patent/BR112016021034A8/pt not_active Application Discontinuation
- 2015-03-12 HU HUE20198371A patent/HUE064818T2/hu unknown
- 2015-03-12 CA CA2942244A patent/CA2942244C/en active Active
- 2015-03-12 EP EP20198371.5A patent/EP3777833B1/en active Active
- 2015-03-12 DK DK20198371.5T patent/DK3777833T3/da active
- 2015-03-12 HR HRP20231716TT patent/HRP20231716T1/hr unknown
- 2015-03-12 HU HUE15731727A patent/HUE052642T2/hu unknown
- 2015-03-12 PL PL20198371.5T patent/PL3777833T3/pl unknown
- 2015-03-12 DK DK15731727.2T patent/DK3116475T3/da active
-
2016
- 2016-09-06 IL IL247668A patent/IL247668B/en active IP Right Grant
-
2018
- 2018-06-14 US US16/008,228 patent/US10624839B2/en active Active
-
2019
- 2019-09-19 JP JP2019170864A patent/JP6770158B2/ja active Active
-
2020
- 2020-03-16 US US16/819,740 patent/US20210038505A1/en not_active Abandoned
- 2020-12-04 HR HRP20201948TT patent/HRP20201948T1/hr unknown
-
2022
- 2022-09-01 US US17/901,078 patent/US20230240980A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL247668A0 (en) | Preparations that include dopa decarboxylase inhibitors | |
IL246362A0 (en) | Novel glutaminase inhibitors | |
IL246785A0 (en) | Benzimidazole-2-amines as midh1 inhibitors | |
SG11201704936SA (en) | Corrosion inhibitor compositions for acidizing treatments | |
HUE046273T2 (hu) | Ciklopropilaminok mint LSD1 inhibitorok | |
HUE045725T2 (hu) | Ciklopropilaminok mint LSD1 inhibitorok | |
HK1226398A1 (zh) | 作為midh1抑制劑的苯並咪唑-2-胺 | |
EP3347333C0 (en) | POLYMERIZATION INHIBITOR COMPOSITIONS | |
GB201403536D0 (en) | Inhibitor compounds | |
ZA201704301B (en) | Microencapsulated nitrification inhibitor compositions | |
LT3227325T (lt) | Selektyvaus il-6-trans signalinio kelio inhibitoriaus kompozicijos | |
HUE050027T2 (hu) | Antioxidáns készítmények | |
IL247921A0 (en) | Glutaminase inhibitor compounds, preparations containing them and their uses | |
GB201411802D0 (en) | Effervescent compositions | |
IL251479B (en) | components | |
GB201408167D0 (en) | Compositions | |
GB201420306D0 (en) | Compositions | |
GB201406542D0 (en) | Intumescent compositions | |
SG11201610860UA (en) | Sweetener compositions | |
GB201401005D0 (en) | Inhibitor | |
GB201501779D0 (en) | NONOate compositions | |
GB201411470D0 (en) | Effervescent compositions | |
GB201419849D0 (en) | Compositions | |
GB201406863D0 (en) | Compositions comprising variegin |