FI3638251T3 - Bisfosfosiinin geeliformulaatioita ja niiden käyttötapoja - Google Patents
Bisfosfosiinin geeliformulaatioita ja niiden käyttötapoja Download PDFInfo
- Publication number
- FI3638251T3 FI3638251T3 FIEP18816615.1T FI18816615T FI3638251T3 FI 3638251 T3 FI3638251 T3 FI 3638251T3 FI 18816615 T FI18816615 T FI 18816615T FI 3638251 T3 FI3638251 T3 FI 3638251T3
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- FI
- Finland
- Prior art keywords
- formulation
- formulation according
- alcohol
- weight
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Ophthalmology & Optometry (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762518262P | 2017-06-12 | 2017-06-12 | |
| PCT/US2018/037151 WO2018231863A1 (en) | 2017-06-12 | 2018-06-12 | Bisphosphocin gel formulations and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI3638251T3 true FI3638251T3 (fi) | 2024-04-29 |
Family
ID=64562861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FIEP18816615.1T FI3638251T3 (fi) | 2017-06-12 | 2018-06-12 | Bisfosfosiinin geeliformulaatioita ja niiden käyttötapoja |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US11096954B2 (https=) |
| EP (2) | EP3638251B1 (https=) |
| JP (2) | JP7148994B2 (https=) |
| KR (3) | KR20260035292A (https=) |
| CN (1) | CN110753549A (https=) |
| AU (3) | AU2018282905B2 (https=) |
| BR (2) | BR112019026073B1 (https=) |
| CA (1) | CA3066722A1 (https=) |
| DK (1) | DK3638251T3 (https=) |
| ES (1) | ES2981923T3 (https=) |
| FI (1) | FI3638251T3 (https=) |
| MX (1) | MX2019014772A (https=) |
| PT (1) | PT3638251T (https=) |
| WO (1) | WO2018231863A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2604943C (en) | 2005-04-15 | 2013-09-17 | Clarus Therapeutics, Inc. | Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same |
| US8492369B2 (en) | 2010-04-12 | 2013-07-23 | Clarus Therapeutics Inc | Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same |
| US12030908B2 (en) | 2017-03-10 | 2024-07-09 | Lakewood Amedex, Inc. | Antimicrobial compounds, compositions, and uses thereof |
| US11377468B2 (en) | 2017-03-10 | 2022-07-05 | Lakewood Amedex, Inc. | Antimicrobial compounds, compositions, and uses thereof |
| US11795192B2 (en) | 2017-03-10 | 2023-10-24 | Lakewood Amedex, Inc. | Antimicrobial compounds, compositions, and uses thereof |
| KR102317158B1 (ko) * | 2017-03-10 | 2021-10-25 | 레이크우드 아메덱스, 인크. | 항미생물 화합물, 조성물, 및 그의 용도 |
| KR20260035292A (ko) | 2017-06-12 | 2026-03-12 | 레이크우드 아메덱스, 인크. | 비스포스포신 겔 제제 및 이의 용도 |
| BR112021006954A2 (pt) * | 2018-10-17 | 2021-07-20 | Lakewood Amedex, Inc. | métodos e composições para tratar mucosite oral |
| US11564933B2 (en) | 2019-04-12 | 2023-01-31 | Tolmar, Inc. | Methods of treating testosterone deficiency |
| JP2024525259A (ja) * | 2021-07-22 | 2024-07-12 | レイクウッド アメデックス、インコーポレイテッド | ビスホスホシンを調製するための方法 |
| WO2025179296A1 (en) * | 2024-02-22 | 2025-08-28 | Lakewood Amedex, Inc. | Crystalline forms of nu-3 and uses thereof |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4105782A (en) | 1975-03-07 | 1978-08-08 | Yu Ruey J | Treatment of acne and dandruff |
| SE8004580L (sv) * | 1980-06-19 | 1981-12-20 | Draco Ab | Farmaceutisk beredning |
| KR830005852A (ko) * | 1980-07-18 | 1983-09-14 | 미첼 페터 잭슨 | 피부와 점막의 비루스 감염치료에 적합한 국소치료제의 제조방법 |
| US4421769A (en) * | 1981-09-29 | 1983-12-20 | The Procter & Gamble Company | Skin conditioning composition |
| DE3542516A1 (de) | 1985-12-02 | 1987-06-04 | Henkel Kgaa | Desinfektionsmittel |
| DE3731255A1 (de) * | 1987-09-17 | 1989-04-06 | Boehringer Ingelheim Int | Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen |
| US5266310A (en) | 1987-09-17 | 1993-11-30 | Boehringer Ingelheim International Gmbh | Stabilization of therapeutically active proteins in pharmaceutical preparations |
| US5153230A (en) | 1989-10-06 | 1992-10-06 | Perfective Cosmetics, Inc. | Topical skin cream composition |
| US5167950A (en) * | 1991-03-28 | 1992-12-01 | S. C. Johnson & Son | High alcohol content aerosol antimicrobial mousse |
| US5208015A (en) * | 1991-07-23 | 1993-05-04 | Bristol-Myers Squibb Company | Topical anti-fungal agents having anti-inflammatory activity |
| DE4333385C2 (de) | 1993-09-30 | 1997-01-30 | Friedrich A Spruegel | Flächendesinfektions- und Reinigungsmittel |
| CZ267396A3 (en) * | 1994-03-11 | 1997-03-12 | Procter & Gamble | HYDROLYTIC STABLE COSMETIC, PREPARATION WITH LOW pH VALUE CONTAINING ACID ACTIVE SUBSTANCES |
| FR2718022B1 (fr) | 1994-04-01 | 1996-04-26 | Roussel Uclaf | Compositions cosmétiques ou dermatologiques et leur préparation. |
| FR2722102B1 (fr) * | 1994-07-11 | 1996-08-23 | Cird Galderma | Utilisation de particules creuses deformables dans une composition cosmetique et/ou dermatologique, contenant des matieres grasses |
| US5843998A (en) | 1997-06-30 | 1998-12-01 | Song; Jin | Skin blemish treatment |
| US6211349B1 (en) | 1998-12-30 | 2001-04-03 | Oligos Etc., Inc. | Protonated/acidified nucleic acids and methods of use |
| US7868162B2 (en) * | 1998-12-30 | 2011-01-11 | Lakewood-Amedex, Inc. | Antimicrobial and antiviral compounds and methods for their use |
| US20020032164A1 (en) | 1998-12-30 | 2002-03-14 | Dale Roderic M. K. | Antimicrobial compounds and methods for their use |
| US6627215B1 (en) | 1998-12-30 | 2003-09-30 | Oligos Etc. Inc. | Devices for improved wound management |
| US6211162B1 (en) | 1998-12-30 | 2001-04-03 | Oligos Etc. Inc. | Pulmonary delivery of protonated/acidified nucleic acids |
| US6156294A (en) | 1999-11-28 | 2000-12-05 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| JP2005511526A (ja) * | 2001-10-18 | 2005-04-28 | イレックス プロダクツ インコーポレイテッド | ジホスホネート誘導体による皮膚の治療方法 |
| WO2004093886A1 (en) * | 2003-04-24 | 2004-11-04 | Galderma S.A. | Topical formulation of ivermectin for the treatment of dermatological conditions |
| CN1687100A (zh) * | 2005-04-05 | 2005-10-26 | 奥林格斯技术有限公司 | 修饰性核苷酸及其用途 |
| EP2149375A1 (en) | 2008-07-28 | 2010-02-03 | Despharma Kft. | Compositions for the treatment of dermatological diseases, and uses thereof |
| EP2419087B1 (en) | 2009-04-13 | 2013-01-23 | Sulur, Vanangamudi Subramaniam | A medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer and a process to make it |
| WO2015075406A1 (en) | 2013-11-19 | 2015-05-28 | Lipopeptide Ab | New treatment of chronic ulcers |
| FR3041540B1 (fr) | 2015-09-29 | 2018-10-26 | Galderma Research & Development | Composition nettoyante auto-moussante a rincer, contenant de l'ivermectine. |
| KR20260035292A (ko) | 2017-06-12 | 2026-03-12 | 레이크우드 아메덱스, 인크. | 비스포스포신 겔 제제 및 이의 용도 |
-
2018
- 2018-06-12 KR KR1020267005083A patent/KR20260035292A/ko active Pending
- 2018-06-12 CA CA3066722A patent/CA3066722A1/en active Pending
- 2018-06-12 DK DK18816615.1T patent/DK3638251T3/da active
- 2018-06-12 EP EP18816615.1A patent/EP3638251B1/en active Active
- 2018-06-12 US US16/006,660 patent/US11096954B2/en active Active
- 2018-06-12 BR BR112019026073-0A patent/BR112019026073B1/pt not_active IP Right Cessation
- 2018-06-12 MX MX2019014772A patent/MX2019014772A/es unknown
- 2018-06-12 AU AU2018282905A patent/AU2018282905B2/en not_active Ceased
- 2018-06-12 EP EP23156658.9A patent/EP4241769A3/en active Pending
- 2018-06-12 PT PT188166151T patent/PT3638251T/pt unknown
- 2018-06-12 ES ES18816615T patent/ES2981923T3/es active Active
- 2018-06-12 KR KR1020207000424A patent/KR20200014904A/ko not_active Abandoned
- 2018-06-12 FI FIEP18816615.1T patent/FI3638251T3/fi active
- 2018-06-12 BR BR122021011439-0A patent/BR122021011439B1/pt active IP Right Grant
- 2018-06-12 CN CN201880038759.5A patent/CN110753549A/zh active Pending
- 2018-06-12 WO PCT/US2018/037151 patent/WO2018231863A1/en not_active Ceased
- 2018-06-12 KR KR1020237004991A patent/KR20230031370A/ko not_active Ceased
- 2018-06-12 JP JP2019567981A patent/JP7148994B2/ja active Active
-
2020
- 2020-07-30 US US16/943,939 patent/US20200360415A1/en not_active Abandoned
-
2021
- 2021-08-09 US US17/396,989 patent/US12156883B2/en active Active
-
2022
- 2022-09-02 AU AU2022224829A patent/AU2022224829B2/en active Active
- 2022-09-15 JP JP2022147051A patent/JP7470449B2/ja active Active
- 2022-12-16 US US18/083,378 patent/US20230125677A1/en not_active Abandoned
-
2024
- 2024-04-05 AU AU2024202211A patent/AU2024202211B2/en active Active
- 2024-10-31 US US18/933,370 patent/US20250262234A1/en active Pending
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