FI20155027A - Polymyksiinijohdannainen ja sen käytöt - Google Patents

Polymyksiinijohdannainen ja sen käytöt

Info

Publication number
FI20155027A
FI20155027A FI20155027A FI20155027A FI20155027A FI 20155027 A FI20155027 A FI 20155027A FI 20155027 A FI20155027 A FI 20155027A FI 20155027 A FI20155027 A FI 20155027A FI 20155027 A FI20155027 A FI 20155027A
Authority
FI
Finland
Prior art keywords
polymyxin derivatives
polymyxin
derivatives
Prior art date
Application number
FI20155027A
Other languages
English (en)
Swedish (sv)
Other versions
FI126143B (fi
Inventor
Martti Vaara
Timo Vaara
Original Assignee
Northern Antibiotics Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FI20155027A priority Critical patent/FI126143B/fi
Application filed by Northern Antibiotics Oy filed Critical Northern Antibiotics Oy
Priority to MX2017009094A priority patent/MX2017009094A/es
Priority to AU2016207942A priority patent/AU2016207942B2/en
Priority to CN201680005506.9A priority patent/CN107207569B/zh
Priority to EP16151398.1A priority patent/EP3045469B1/en
Priority to DK16151398.1T priority patent/DK3045469T3/en
Priority to CA2972743A priority patent/CA2972743C/en
Priority to SG11201705125UA priority patent/SG11201705125UA/en
Priority to ES16151398.1T priority patent/ES2656562T3/es
Priority to PT161513981T priority patent/PT3045469T/pt
Priority to PCT/FI2016/050016 priority patent/WO2016113470A1/en
Priority to HUE16151398A priority patent/HUE035778T2/hu
Priority to NO16151398A priority patent/NO3045469T3/no
Priority to TW105101251A priority patent/TWI694087B/zh
Priority to BR112017014670-3A priority patent/BR112017014670A2/pt
Priority to KR1020177022255A priority patent/KR102020886B1/ko
Priority to RU2017127011A priority patent/RU2675819C1/ru
Priority to JP2017536921A priority patent/JP6471236B2/ja
Publication of FI20155027A publication Critical patent/FI20155027A/fi
Publication of FI126143B publication Critical patent/FI126143B/fi
Application granted granted Critical
Priority to IL25345717A priority patent/IL253457B/en
Priority to HRP20180180TT priority patent/HRP20180180T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62—Polymyxins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI20155027A 2015-01-15 2015-01-15 Polymyksiinijohdannainen ja sen käytöt FI126143B (fi)

Priority Applications (20)

Application Number Priority Date Filing Date Title
FI20155027A FI126143B (fi) 2015-01-15 2015-01-15 Polymyksiinijohdannainen ja sen käytöt
NO16151398A NO3045469T3 (fi) 2015-01-15 2016-01-15
AU2016207942A AU2016207942B2 (en) 2015-01-15 2016-01-15 Polymyxin derivative and uses thereof
EP16151398.1A EP3045469B1 (en) 2015-01-15 2016-01-15 Polymyxin derivative and uses thereof
DK16151398.1T DK3045469T3 (en) 2015-01-15 2016-01-15 Polymyxin derivative and uses thereof
CA2972743A CA2972743C (en) 2015-01-15 2016-01-15 Polymyxin derivative and uses thereof
SG11201705125UA SG11201705125UA (en) 2015-01-15 2016-01-15 Polymyxin derivative and uses thereof
ES16151398.1T ES2656562T3 (es) 2015-01-15 2016-01-15 Derivado de polimixina y usos del mismo
TW105101251A TWI694087B (zh) 2015-01-15 2016-01-15 多黏桿菌素衍生物及其用途
PCT/FI2016/050016 WO2016113470A1 (en) 2015-01-15 2016-01-15 Polymyxin derivative and uses thereof
MX2017009094A MX2017009094A (es) 2015-01-15 2016-01-15 Derivado de polimixina y usos del mismo.
CN201680005506.9A CN107207569B (zh) 2015-01-15 2016-01-15 多黏菌素衍生物及其用途
PT161513981T PT3045469T (pt) 2015-01-15 2016-01-15 Derivado da polimixina e seus usos
BR112017014670-3A BR112017014670A2 (pt) 2015-01-15 2016-01-15 derivado de polimixina e usos do mesmo
KR1020177022255A KR102020886B1 (ko) 2015-01-15 2016-01-15 폴리믹신 유도체 및 이의 용도
RU2017127011A RU2675819C1 (ru) 2015-01-15 2016-01-15 Производные полимиксина и их применение
JP2017536921A JP6471236B2 (ja) 2015-01-15 2016-01-15 ポリミキシン誘導体およびその使用
HUE16151398A HUE035778T2 (hu) 2015-01-15 2016-01-15 Polimixin származék és alkalmazásai
IL25345717A IL253457B (en) 2015-01-15 2017-07-12 Polymyxin derivatives, preparations containing them and their uses
HRP20180180TT HRP20180180T1 (hr) 2015-01-15 2018-01-31 Derivat polimiksina i njegova uporaba

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20155027A FI126143B (fi) 2015-01-15 2015-01-15 Polymyksiinijohdannainen ja sen käytöt

Publications (2)

Publication Number Publication Date
FI126143B FI126143B (fi) 2016-07-15
FI20155027A true FI20155027A (fi) 2016-07-15

Family

ID=55310836

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20155027A FI126143B (fi) 2015-01-15 2015-01-15 Polymyksiinijohdannainen ja sen käytöt

Country Status (20)

Country Link
EP (1) EP3045469B1 (fi)
JP (1) JP6471236B2 (fi)
KR (1) KR102020886B1 (fi)
CN (1) CN107207569B (fi)
AU (1) AU2016207942B2 (fi)
BR (1) BR112017014670A2 (fi)
CA (1) CA2972743C (fi)
DK (1) DK3045469T3 (fi)
ES (1) ES2656562T3 (fi)
FI (1) FI126143B (fi)
HR (1) HRP20180180T1 (fi)
HU (1) HUE035778T2 (fi)
IL (1) IL253457B (fi)
MX (1) MX2017009094A (fi)
NO (1) NO3045469T3 (fi)
PT (1) PT3045469T (fi)
RU (1) RU2675819C1 (fi)
SG (1) SG11201705125UA (fi)
TW (1) TWI694087B (fi)
WO (1) WO2016113470A1 (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018108154A1 (zh) * 2016-12-16 2018-06-21 中国医学科学院医药生物技术研究所 多粘菌素衍生物及其制备方法和应用
GB201703898D0 (en) 2017-03-10 2017-04-26 Helperby Therapeautics Ltd Method
GB201704620D0 (en) * 2017-03-23 2017-05-10 Helperby Therapeautics Ltd Combinations
CN107661349A (zh) * 2017-11-24 2018-02-06 刘晓峰 一种治疗小儿高热的联合用药物
CN110179967A (zh) * 2019-05-28 2019-08-30 中国医药集团总公司四川抗菌素工业研究所 多粘菌素母核和一种抗生素的组合物及其应用
IT201900025414A1 (it) 2019-12-23 2021-06-23 Univ Bologna Alma Mater Studiorum Composto per il trattamento della sindrome emolitico uremica
CN117083288A (zh) * 2021-03-31 2023-11-17 江苏奥赛康药业有限公司 一种多粘菌素衍生物的硫酸盐及其药物组合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754411A (fr) * 1969-08-05 1971-02-04 Rhone Poulenc Sa Cyclopeptides derives des polymyxines et leur
TW274552B (fi) * 1992-05-26 1996-04-21 Hoechst Ag
US20060004185A1 (en) 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
US7807637B2 (en) 2006-08-11 2010-10-05 Northern Antibiotics Oy Polymyxin derivatives and uses thereof
ES2575521T3 (es) * 2006-08-11 2016-06-29 Northern Antibiotics Oy Derivados de polimixina y sus usos
FI20085469A0 (fi) * 2008-02-08 2008-05-16 Northern Antibiotics Oy Polymyksiinijohdannaiset, joissa on lyhyt rasvahappohäntä, ja niiden käyttöjä
EP2780357A1 (en) 2011-11-18 2014-09-24 Novacta Biosystems Limited Polymyxin derivatives
CA2895910C (en) * 2013-01-11 2021-12-21 Xellia Pharmaceuticals Aps Polymyxins, compositions, methods of making and methods of use
PL2999711T3 (pl) 2013-05-22 2022-09-26 Spero Therapeutics, Inc. Pochodne polimyksyny i ich zastosowanie w terapii skojarzonej razem z różnymi antybiotykami

Also Published As

Publication number Publication date
PT3045469T (pt) 2018-02-08
ES2656562T3 (es) 2018-02-27
SG11201705125UA (en) 2017-07-28
CA2972743C (en) 2020-06-09
BR112017014670A2 (pt) 2018-03-13
WO2016113470A1 (en) 2016-07-21
CN107207569B (zh) 2020-11-03
FI126143B (fi) 2016-07-15
EP3045469B1 (en) 2017-11-29
DK3045469T3 (en) 2018-03-05
NO3045469T3 (fi) 2018-04-28
RU2675819C1 (ru) 2018-12-25
AU2016207942A1 (en) 2017-08-10
JP2018505868A (ja) 2018-03-01
EP3045469A1 (en) 2016-07-20
MX2017009094A (es) 2018-03-01
TWI694087B (zh) 2020-05-21
CA2972743A1 (en) 2016-07-21
IL253457B (en) 2019-10-31
IL253457A0 (en) 2017-09-28
KR20170102005A (ko) 2017-09-06
HRP20180180T1 (hr) 2018-03-09
HUE035778T2 (hu) 2018-08-28
CN107207569A (zh) 2017-09-26
TW201630930A (zh) 2016-09-01
KR102020886B1 (ko) 2019-09-16
JP6471236B2 (ja) 2019-02-13
AU2016207942B2 (en) 2018-05-10

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