SG11201705125UA - Polymyxin derivative and uses thereof - Google Patents

Polymyxin derivative and uses thereof

Info

Publication number
SG11201705125UA
SG11201705125UA SG11201705125UA SG11201705125UA SG11201705125UA SG 11201705125U A SG11201705125U A SG 11201705125UA SG 11201705125U A SG11201705125U A SG 11201705125UA SG 11201705125U A SG11201705125U A SG 11201705125UA SG 11201705125U A SG11201705125U A SG 11201705125UA
Authority
SG
Singapore
Prior art keywords
polymyxin derivative
polymyxin
derivative
Prior art date
Application number
SG11201705125UA
Inventor
Martti Vaara
Timo Vaara
Original Assignee
Northern Antibiotics Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northern Antibiotics Oy filed Critical Northern Antibiotics Oy
Publication of SG11201705125UA publication Critical patent/SG11201705125UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62Polymyxins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SG11201705125UA 2015-01-15 2016-01-15 Polymyxin derivative and uses thereof SG11201705125UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20155027A FI126143B (en) 2015-01-15 2015-01-15 Polymyxin derivatives and uses thereof
PCT/FI2016/050016 WO2016113470A1 (en) 2015-01-15 2016-01-15 Polymyxin derivative and uses thereof

Publications (1)

Publication Number Publication Date
SG11201705125UA true SG11201705125UA (en) 2017-07-28

Family

ID=55310836

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201705125UA SG11201705125UA (en) 2015-01-15 2016-01-15 Polymyxin derivative and uses thereof

Country Status (20)

Country Link
EP (1) EP3045469B1 (en)
JP (1) JP6471236B2 (en)
KR (1) KR102020886B1 (en)
CN (1) CN107207569B (en)
AU (1) AU2016207942B2 (en)
BR (1) BR112017014670A2 (en)
CA (1) CA2972743C (en)
DK (1) DK3045469T3 (en)
ES (1) ES2656562T3 (en)
FI (1) FI126143B (en)
HR (1) HRP20180180T1 (en)
HU (1) HUE035778T2 (en)
IL (1) IL253457B (en)
MX (1) MX2017009094A (en)
NO (1) NO3045469T3 (en)
PT (1) PT3045469T (en)
RU (1) RU2675819C1 (en)
SG (1) SG11201705125UA (en)
TW (1) TWI694087B (en)
WO (1) WO2016113470A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110072878B (en) * 2016-12-16 2021-07-23 中国医学科学院医药生物技术研究所 Polymyxin derivatives, preparation method and application thereof
GB201703898D0 (en) 2017-03-10 2017-04-26 Helperby Therapeautics Ltd Method
GB201704620D0 (en) 2017-03-23 2017-05-10 Helperby Therapeautics Ltd Combinations
CN107661349A (en) * 2017-11-24 2018-02-06 刘晓峰 A kind of combination medicine for treating infantile hyperpyrexia
CN110179967A (en) * 2019-05-28 2019-08-30 中国医药集团总公司四川抗菌素工业研究所 The composition and its application of polymyxins parent nucleus and a kind of antibiotic
IT201900025414A1 (en) 2019-12-23 2021-06-23 Univ Bologna Alma Mater Studiorum COMPOUND FOR THE TREATMENT OF UREMIC HEMOLITIC SYNDROME
CN117083288A (en) * 2021-03-31 2023-11-17 江苏奥赛康药业有限公司 Sulfate of polymyxin derivative and pharmaceutical composition thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754411A (en) * 1969-08-05 1971-02-04 Rhone Poulenc Sa CYCLOPEPTIDES DERIVED FROM POLYMYXINS AND THEIR
TW274552B (en) * 1992-05-26 1996-04-21 Hoechst Ag
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
CA2694289C (en) * 2006-08-11 2015-04-07 Northern Antibiotics Oy Polymyxin derivatives and uses thereof
US7807637B2 (en) 2006-08-11 2010-10-05 Northern Antibiotics Oy Polymyxin derivatives and uses thereof
FI20085469A0 (en) * 2008-02-08 2008-05-16 Northern Antibiotics Oy Polymyxin derivatives with short fatty acid tails and their uses
WO2013072695A1 (en) 2011-11-18 2013-05-23 Novacta Biosystems Limited Polymyxin derivatives
US10640536B2 (en) * 2013-01-11 2020-05-05 Xellia Pharmaceuticals Aps Polymyxins, compositions, methods of making and methods of use
BR112015029309A2 (en) 2013-05-22 2017-07-25 New Pharma Licence Holdings Ltd polymyxin derivatives and their use in combination therapy with different antibiotics

Also Published As

Publication number Publication date
DK3045469T3 (en) 2018-03-05
IL253457A0 (en) 2017-09-28
WO2016113470A1 (en) 2016-07-21
CN107207569B (en) 2020-11-03
HRP20180180T1 (en) 2018-03-09
KR20170102005A (en) 2017-09-06
JP6471236B2 (en) 2019-02-13
BR112017014670A2 (en) 2018-03-13
ES2656562T3 (en) 2018-02-27
NO3045469T3 (en) 2018-04-28
CA2972743A1 (en) 2016-07-21
EP3045469B1 (en) 2017-11-29
KR102020886B1 (en) 2019-09-16
JP2018505868A (en) 2018-03-01
HUE035778T2 (en) 2018-08-28
RU2675819C1 (en) 2018-12-25
TWI694087B (en) 2020-05-21
IL253457B (en) 2019-10-31
CA2972743C (en) 2020-06-09
FI126143B (en) 2016-07-15
EP3045469A1 (en) 2016-07-20
AU2016207942A1 (en) 2017-08-10
PT3045469T (en) 2018-02-08
TW201630930A (en) 2016-09-01
AU2016207942B2 (en) 2018-05-10
FI20155027A (en) 2016-07-15
CN107207569A (en) 2017-09-26
MX2017009094A (en) 2018-03-01

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