FI118626B - Kooloniin annettava lääkekoostumus - Google Patents

Kooloniin annettava lääkekoostumus Download PDF

Info

Publication number
FI118626B
FI118626B FI965154A FI965154A FI118626B FI 118626 B FI118626 B FI 118626B FI 965154 A FI965154 A FI 965154A FI 965154 A FI965154 A FI 965154A FI 118626 B FI118626 B FI 118626B
Authority
FI
Finland
Prior art keywords
drug
colon
coating
delivery composition
drug delivery
Prior art date
Application number
FI965154A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI965154A0 (fi
FI965154A (fi
Inventor
Peter Watts
Original Assignee
Archimedes Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Archimedes Dev Ltd filed Critical Archimedes Dev Ltd
Publication of FI965154A0 publication Critical patent/FI965154A0/fi
Publication of FI965154A publication Critical patent/FI965154A/fi
Application granted granted Critical
Publication of FI118626B publication Critical patent/FI118626B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI965154A 1994-06-21 1996-12-20 Kooloniin annettava lääkekoostumus FI118626B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9412394 1994-06-21
GB9412394A GB9412394D0 (en) 1994-06-21 1994-06-21 Colonic drug delivery composition
GB9501458 1995-06-21
PCT/GB1995/001458 WO1995035100A1 (en) 1994-06-21 1995-06-21 Colonic drug delivery composition

Publications (3)

Publication Number Publication Date
FI965154A0 FI965154A0 (fi) 1996-12-20
FI965154A FI965154A (fi) 1997-02-20
FI118626B true FI118626B (fi) 2008-01-31

Family

ID=10757052

Family Applications (1)

Application Number Title Priority Date Filing Date
FI965154A FI118626B (fi) 1994-06-21 1996-12-20 Kooloniin annettava lääkekoostumus

Country Status (14)

Country Link
US (2) US6228396B1 (de)
EP (1) EP0810857B1 (de)
JP (1) JP2986217B2 (de)
AT (1) ATE204751T1 (de)
AU (1) AU688060B2 (de)
CA (1) CA2193481C (de)
DE (1) DE69522475T2 (de)
DK (1) DK0810857T3 (de)
ES (1) ES2162922T3 (de)
FI (1) FI118626B (de)
GB (1) GB9412394D0 (de)
NO (1) NO315686B1 (de)
PT (1) PT810857E (de)
WO (1) WO1995035100A1 (de)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686106A (en) * 1995-05-17 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form for colonic delivery
GB9620709D0 (en) * 1996-10-04 1996-11-20 Danbiosyst Uk Colonic delivery of weak acid drugs
KR20000053327A (ko) * 1996-11-15 2000-08-25 데이비드 엠 모이어 결장내 운반에 사용되는 약학적 제형
US5891474A (en) * 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
GB9800912D0 (en) * 1998-01-17 1998-03-11 Danbiosyst Uk New composition
AU735084B2 (en) * 1998-02-09 2001-06-28 Joel Bolonick Treatment of chronic inflammatory disorders of the gastrointestinal tract
US7022683B1 (en) 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
JP5068401B2 (ja) * 1998-09-28 2012-11-07 カプスゲル・ベルギウム・ナムローゼ・フェンノートシャップ Ｈｐｍｃカプセルを使用する腸及び結腸への送達
DE19923817A1 (de) * 1999-05-18 2000-11-23 Roland Bodmeier Kapsel mit kontrollierter Wirkstofffreisetzung
EP1184038B1 (de) * 1999-06-09 2005-12-28 Mochida Pharmaceutical Co., Ltd. System für wirkstofffreisetzung im unteren verdauungstrakt
US6340473B1 (en) * 1999-07-07 2002-01-22 R.P. Scherer Technologies, Inc. Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same
IT1318625B1 (it) * 2000-07-14 2003-08-27 Roberto Valducci Formulazioni farmaceutiche solide orali a rilascio multifasicoph-dipendente.
WO2002040039A2 (en) 2000-11-20 2002-05-23 Dow Global Technologies Inc. In vivo use of water absorbent polymers
US7494669B2 (en) * 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
ES2376739T3 (es) 2001-03-27 2012-03-16 Galectin Therapeutics Inc. Administración conjunta de un polisacárido con un agente quimioterapéutico para el tratamiento del cáncer
US6645946B1 (en) 2001-03-27 2003-11-11 Pro-Pharmaceuticals, Inc. Delivery of a therapeutic agent in a formulation for reduced toxicity
EP1539208A2 (de) * 2002-06-28 2005-06-15 Nastech Pharmaceutical Company Inc. ZUSAMMENSETZUNGEN UND VERFAHREN ZUR MODULIERUNG DER PHYSIOLOGIE VON EPITHEL-VERBINDUNGS-ADHûSIONSMOLEK LEN ZUR VERBESSERTEN MUKOSALEN ABGABE VON THERAPEUTISCHEN MITTELN
US11116782B2 (en) 2002-10-15 2021-09-14 Celgene Corporation Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
US8404716B2 (en) 2002-10-15 2013-03-26 Celgene Corporation Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
US8404717B2 (en) * 2002-10-15 2013-03-26 Celgene Corporation Methods of treating myelodysplastic syndromes using lenalidomide
TWI355276B (en) * 2003-01-14 2012-01-01 Akira Tsuji Gastrointestinal absorption enhancer mediated by p
EP1620732A2 (de) * 2003-04-30 2006-02-01 Nastech Pharmaceutical Company Inc. Unterexpression von claudin als marker von tumor-metastasen
WO2005007110A2 (en) * 2003-07-11 2005-01-27 Pro-Pharmaceuticals, Inc. Compositions and methods for hydrophobic drug delivery
US7825106B2 (en) 2003-09-03 2010-11-02 Agi Therapeutics Ltd. Modified release formulations and methods of treating inflammatory bowel disease
US7737133B2 (en) 2003-09-03 2010-06-15 Agi Therapeutics Ltd. Formulations and methods of treating inflammatory bowel disease
US20050053664A1 (en) * 2003-09-08 2005-03-10 Eliezer Zomer Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer
US20050129679A1 (en) * 2003-12-15 2005-06-16 Nastech Pharmaceutical Company Inc. Method for opening tight junctions
WO2005079314A2 (en) * 2004-02-13 2005-09-01 Pro-Pharmaceuticals, Inc. Compositions and methods used to treat acne and candida
US20040224019A1 (en) * 2004-03-03 2004-11-11 Adi Shefer Oral controlled release system for targeted drug delivery into the cell and its nucleus for gene therapy, DNA vaccination, and administration of gene based drugs
WO2006017417A2 (en) * 2004-08-02 2006-02-16 Pro-Pharmaceuticals, Inc. Compositions and methods for the enhancement of chemotherapy with microbial cytotoxins
GB0421121D0 (en) 2004-09-22 2004-10-27 Natrocell Technologies Ltd Composite rodenticide
GB0517957D0 (en) 2005-09-03 2005-10-12 Morvus Technology Ltd Method of combating infection
GB0526552D0 (en) 2005-12-29 2006-02-08 Morvus Technology Ltd New use
US7964215B1 (en) 2006-01-24 2011-06-21 Emet Pharmaceuticals, LLC Delayed release dosage form
GB0607534D0 (en) * 2006-04-13 2006-05-24 Univ London Pharmacy Colonic drug delivery formulation
WO2008028193A2 (en) * 2006-09-01 2008-03-06 Pharmion Corporation Colon-targeted oral formulations of cytidine analogs
US9227011B2 (en) * 2006-09-29 2016-01-05 MEDIMETRICS Personalized Drug Delivery B.V. Miniaturized threshold sensor
GB2442202A (en) 2006-09-30 2008-04-02 Morvus Technology Ltd Vermin poison
EP2066309B1 (de) 2007-04-04 2012-08-29 Sigmoid Pharma Limited Orale pharmazeutische zusammensetzung
US20090036414A1 (en) * 2007-08-02 2009-02-05 Mutual Pharmaceutical Company, Inc. Mesalamine Formulations
WO2009126742A2 (en) * 2008-04-08 2009-10-15 Appian Labs, Llc Enzyme mediated delivery system
GB0808537D0 (en) 2008-05-12 2008-06-18 Archimedes Dev Ltd Compositions
WO2009139888A1 (en) 2008-05-15 2009-11-19 Celgene Corporation Oral formulations of cytidine analogs and methods of use thereof
CA2743491C (en) 2008-11-11 2016-10-11 Zelton Dave Sharp Inhibition of mammalian target of rapamycin
US9283211B1 (en) 2009-11-11 2016-03-15 Rapamycin Holdings, Llc Oral rapamycin preparation and use for stomatitis
US20170079962A1 (en) 2009-11-11 2017-03-23 Rapamycin Holdings, Llc Oral Rapamycin Preparation and Use for Stomatitus
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
US20120276056A1 (en) * 2011-04-26 2012-11-01 Wieslaw Janusz Bochenek Method for Use of Biologic Agents Including Live or Dormant Forms of Bacteria and other organisms in Treating Infections, Inflammation and Other Diseases of Distal Small Intestine and Large Intestine
KR20200137035A (ko) 2012-01-06 2020-12-08 앤지 파마 유에스 엘엘씨 바이구아나이드 조성물 및 대사 장애를 치료하는 방법
BR112014024159A2 (pt) * 2012-03-29 2017-06-20 Therabiome Llc Formulações de vacina oral específicas do local gastrintestinal , ativas no íleo e apêndice.
US20140066837A1 (en) 2012-07-26 2014-03-06 Ronald L. Moy Skin care compositions and methods
US20160030401A1 (en) 2013-03-13 2016-02-04 The Board Of Regents Of The University Of Texas System Use of mtor inhibitors for prevention of intestinal polyp growth and cancer
US9907755B2 (en) 2013-03-14 2018-03-06 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
KR20150140649A (ko) 2013-04-05 2015-12-16 폴리켐 에스.에이. 과민성 대장 증후군을 치료하기 위한 피도티모드의 사용
BR112015025296A2 (pt) * 2013-04-05 2017-07-18 Polichem Sa uso de pidotimod para o tratamento de doença inflamatória intestinal
US9700544B2 (en) 2013-12-31 2017-07-11 Neal K Vail Oral rapamycin nanoparticle preparations
CA3206208A1 (en) 2013-12-31 2015-07-09 Rapamycin Holdings, Llc Oral rapamycin nanoparticle preparations and use
DK3107568T3 (da) * 2014-02-20 2024-06-03 Vaxart Inc Formuleringer til indgivelse til tyndtarmen
SI3182996T1 (sl) 2014-08-22 2023-04-28 Celgene Corporation Postopki zdravljenja multiplega mieloma z imunomodulatornimi spojinami v kombinaciji s protitelesi
CN118045170A (zh) 2015-06-12 2024-05-17 瓦克萨特公司 用于rsv和诺如病毒抗原的小肠递送的制剂
PE20181295A1 (es) 2015-09-01 2018-08-07 First Wave Bio Inc Metodos y composiciones para tratar afecciones asociadas a una respuesta inflamatoria anomala
US10588864B2 (en) 2016-03-11 2020-03-17 Gateway Pharmaceuticals LLC Pharmaceutical compositions for colon-specific delivery
CN106380636B (zh) * 2016-08-30 2019-05-14 华南理工大学 一种壳聚糖接枝的抗消化淀粉载体材料及其制备方法和应用
CN108201531A (zh) * 2016-12-19 2018-06-26 湖南尔康湘药制药有限公司 高溶解性磺苄西林钠结肠靶向淀粉胶囊及其制备方法
EP3612196A4 (de) 2017-04-18 2021-01-13 Actorius Innovations and Research Pvt. Ltd. Auf polymer basierende formulierung zur freisetzung von wirkstoffen und biowirkstoffen an spezifischen git-stellen
WO2019211419A1 (en) * 2018-05-03 2019-11-07 M.W. Encap Limited Dosage forms for delivery of medicines to the lower gastrointestinal tract
US20230102999A1 (en) 2020-01-10 2023-03-30 First Wave Bio, Inc. Deuterated niclosamide
US20230190684A1 (en) 2020-03-16 2023-06-22 First Wave Bio, Inc. Methods of treating covid-19 with a niclosamide compound
US10980756B1 (en) 2020-03-16 2021-04-20 First Wave Bio, Inc. Methods of treatment
EP4327806A4 (de) 2021-04-20 2024-10-23 Jiangsu Hengrui Pharmaceuticals Co Ltd Kapsel zur spezifischen arzneimittelabgabe und herstellungsverfahren dafür
US11896719B2 (en) 2022-01-24 2024-02-13 Calliditas Therapeutics Ab Pharmaceutical compositions

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA825384B (en) * 1981-07-31 1983-05-25 Tillott J B Ltd Orally administrable pharmaceutical compositions
US4738724A (en) * 1983-11-04 1988-04-19 Warner-Lambert Company Method for forming pharmaceutical capsules from starch compositions
US4673438A (en) * 1984-02-13 1987-06-16 Warner-Lambert Company Polymer composition for injection molding
US4663308A (en) 1984-07-18 1987-05-05 Medical College Of Ohio Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointestinal tract
US4627851A (en) 1984-10-26 1986-12-09 Alza Corporation Colonic-therapeutic delivery system
US4668517A (en) 1985-04-04 1987-05-26 Norwich Eaton Pharmaceuticals, Inc. Furazolidone dosage form
IL77186A0 (en) * 1985-11-29 1986-04-29 Touitou Elka Pharmaceutical insulin composition
US4945080A (en) * 1987-05-26 1990-07-31 Eli Lilly And Company Dirithromycin metabolite
EP0313845A1 (de) * 1987-09-29 1989-05-03 Warner-Lambert Company Stabilisierung von enterischen beschichteten Dosierungsformen
DE3869337D1 (de) * 1987-11-20 1992-04-23 Greither Peter Kapsel und verfahren zu ihrer herstellung.
DE8715583U1 (de) * 1987-11-24 1988-01-28 Greither, Peter, Kirchberg Kapsel
DE3812799A1 (de) 1988-04-16 1989-10-26 Sanol Arznei Schwarz Gmbh Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung
GB8812490D0 (en) 1988-05-26 1988-06-29 Agricultural & Food Res Delayed release formulations
US5342624A (en) * 1989-02-16 1994-08-30 British Technology Group Ltd. Dispensing device
CA2032475C (en) 1989-05-11 1997-12-30 Heiji Ikushima Pharmaceutical preparations for oral administration that are adapted to release the drug at appropriate sites in the intestines
US5032405A (en) * 1989-09-27 1991-07-16 Warner-Lambert Company Oral pharmaceutical composition for acid sensitive proteinaceous agents
BE1003677A3 (nl) * 1990-01-29 1992-05-19 Schacht Etienne Werkwijze voor het bereiden van azobevattende polymeren en het gebruik ervan als geneesmiddelafgiftesystemen.
IL98087A (en) * 1990-05-04 1996-11-14 Perio Prod Ltd Preparation for dispensing drugs in the colon
WO1992018147A1 (en) * 1991-04-19 1992-10-29 Affinity Biotech, Inc. Convertible microemulsion formulations
WO1993009785A1 (en) * 1991-11-22 1993-05-27 Procter & Gamble Pharmaceuticals, Inc. Risedronate delayed-release compositions
DE4236025A1 (de) 1992-10-24 1994-04-28 Merck Patent Gmbh Orale Arzneiformen
US5656290A (en) 1993-02-26 1997-08-12 The Procter & Gamble Company Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
US5686105A (en) 1993-10-19 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
BR9405836A (pt) 1993-02-26 1996-01-16 Procter & Gamble Forma de dosagem de bisacodil
US5651983A (en) * 1993-02-26 1997-07-29 The Procter & Gamble Company Bisacodyl dosage form for colonic delivery
DE69425453T2 (de) 1993-04-23 2001-04-12 Novartis Ag, Basel Wirkstoffabgabevorrichtung mit gesteuerter Freigabe
DE4329503A1 (de) 1993-09-01 1995-03-02 Galenik Labor Freiburg Gmbh Pharmazeutische Präparate zur gezielten Behandlung von Morbus Crohn und Colitis Ulcerosa
AU7961094A (en) 1993-10-19 1995-05-08 Procter & Gamble Company, The Picosulphate dosage form
US5514663A (en) 1993-10-19 1996-05-07 The Procter & Gamble Company Senna dosage form
JPH09510182A (ja) * 1993-11-17 1997-10-14 エルディーエス・テクノロジーズ・インコーポレーテッド カプセル封入されたドラッグデリバリー用透明液
US5482718A (en) 1994-03-23 1996-01-09 Hoffmann-La Roche Inc. Colon-targeted delivery system
US5686106A (en) 1995-05-17 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form for colonic delivery
US5891474A (en) * 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same

Also Published As

Publication number Publication date
JP2986217B2 (ja) 1999-12-06
AU688060B2 (en) 1998-03-05
NO965436L (no) 1996-12-18
US6228396B1 (en) 2001-05-08
US20010026807A1 (en) 2001-10-04
CA2193481A1 (en) 1995-12-28
DK0810857T3 (da) 2001-10-08
ATE204751T1 (de) 2001-09-15
AU2746095A (en) 1996-01-15
ES2162922T3 (es) 2002-01-16
EP0810857A1 (de) 1997-12-10
JPH09510478A (ja) 1997-10-21
NO315686B1 (no) 2003-10-13
FI965154A0 (fi) 1996-12-20
FI965154A (fi) 1997-02-20
PT810857E (pt) 2001-12-28
GB9412394D0 (en) 1994-08-10
WO1995035100A1 (en) 1995-12-28
EP0810857B1 (de) 2001-08-29
DE69522475T2 (de) 2002-05-08
CA2193481C (en) 2001-03-20
NO965436D0 (no) 1996-12-18
DE69522475D1 (de) 2001-10-04

Similar Documents

Publication Publication Date Title
FI118626B (fi) Kooloniin annettava lääkekoostumus
AU757343B2 (en) Enteric and colonic delivery using HPMC capsules
EP0827398B1 (de) Pharmazeutische dosierungsform zur freisetzung im colon
EP1916995B1 (de) Ph-kontrolliertes pulsierendes abgabesystem, herstellungsverfahren und verwendung
WO1999037290A1 (en) Novel dosage form
AU679852B2 (en) Stabilized composition for oral administration of peptides
US20050249800A1 (en) System for release in lower gastrointestinal tract
EP0825854A1 (de) Pharmazeutische dosisform mit mehrfacher darmlöslicher polymerbeschichtung zur wirkstoffabgabe im kolon
JP2967492B2 (ja) 腸内適所放出経口製剤
AU732210B2 (en) Colonic delivery of weak acid drugs
Kendall et al. The role of polymers in solid oral dosage forms
JP3122478B2 (ja) 下部消化管放出型経口製剤
WO1998022096A1 (en) Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
Nykänen Development of multiple-unit oral formulations for colon-specific drug delivery using enteric polymers and organic acids as excipients
KR100212432B1 (ko) 대장 약물전달 조성물
AU7732496A (en) Pharmaceutical dosage form for colonic delivery
NZ565272A (en) pH-controlled pulsatile delivery system, methods for preparation and use thereof

Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: ARCHIMEDES DEVELOPMENT LIMITED

Free format text: ARCHIMEDES DEVELOPMENT LIMITED

FG Patent granted

Ref document number: 118626

Country of ref document: FI

MA Patent expired