FI117977B - Menetelmä tromboosiin ja/tai huonoon antikoagulanttivasteeseen aktivoituun proteiini C:hen liittyvän geenivirheen läsnäolon seulomiseksi - Google Patents

Menetelmä tromboosiin ja/tai huonoon antikoagulanttivasteeseen aktivoituun proteiini C:hen liittyvän geenivirheen läsnäolon seulomiseksi Download PDF

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Publication number
FI117977B
FI117977B FI954855A FI954855A FI117977B FI 117977 B FI117977 B FI 117977B FI 954855 A FI954855 A FI 954855A FI 954855 A FI954855 A FI 954855A FI 117977 B FI117977 B FI 117977B
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factor
apc
mutation
nucleic acid
protein
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FI954855A
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Finnish (fi)
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FI954855A (fi
FI954855A0 (fi
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Rogier Maria Bertina
Pieter Hendrik Reitsma
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Rijks Universiteit Leiden
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FI954855A 1994-02-14 1995-10-12 Menetelmä tromboosiin ja/tai huonoon antikoagulanttivasteeseen aktivoituun proteiini C:hen liittyvän geenivirheen läsnäolon seulomiseksi FI117977B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP94200377 1994-02-14
EP94200377 1994-02-14
PCT/EP1995/000553 WO1995021938A1 (en) 1994-02-14 1995-02-14 A method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein c
EP9500553 1995-02-14

Publications (3)

Publication Number Publication Date
FI954855A0 FI954855A0 (fi) 1995-10-12
FI954855A FI954855A (fi) 1995-11-17
FI117977B true FI117977B (fi) 2007-05-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
FI954855A FI117977B (fi) 1994-02-14 1995-10-12 Menetelmä tromboosiin ja/tai huonoon antikoagulanttivasteeseen aktivoituun proteiini C:hen liittyvän geenivirheen läsnäolon seulomiseksi

Country Status (14)

Country Link
US (3) US6518016B1 (ja)
EP (2) EP0696325B1 (ja)
JP (2) JP3163105B2 (ja)
KR (1) KR100384251B1 (ja)
AT (2) ATE166110T1 (ja)
AU (1) AU690644B2 (ja)
CA (1) CA2159907C (ja)
DE (3) DE696325T1 (ja)
DK (2) DK0807691T3 (ja)
ES (2) ES2166948T3 (ja)
FI (1) FI117977B (ja)
GR (2) GR960300034T1 (ja)
PT (1) PT807691E (ja)
WO (1) WO1995021938A1 (ja)

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US20030143759A1 (en) * 1995-10-20 2003-07-31 Bjorn Dahlback Assays for determining anticoagulant cofactor activity
US5766869A (en) * 1995-11-30 1998-06-16 Ahs Hospital Corp. Factor V ratio blood test for susceptibility to thromboembolism
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AT404993B (de) * 1997-01-13 1999-04-26 Immuno Ag Verfahren zur bestimmung eines proteins mit einer mutation
US6451526B1 (en) * 1998-01-20 2002-09-17 Mayo Foundation For Medical Education And Research Simplified mutation detection
DE19802377A1 (de) 1998-01-22 1999-08-19 Max Planck Gesellschaft Verwendung von Inhibitoren für die Behandlung von RTK-Überfunktions-bedingten Störungen, insbesondere von Krebs
US6268146B1 (en) 1998-03-13 2001-07-31 Promega Corporation Analytical methods and materials for nucleic acid detection
US6270974B1 (en) 1998-03-13 2001-08-07 Promega Corporation Exogenous nucleic acid detection
US6312902B1 (en) 1998-03-13 2001-11-06 Promega Corporation Nucleic acid detection
US6335162B1 (en) 1998-03-13 2002-01-01 Promega Corporation Nucleic acid detection
US6235480B1 (en) 1998-03-13 2001-05-22 Promega Corporation Detection of nucleic acid hybrids
US6391551B1 (en) 1998-03-13 2002-05-21 Promega Corporation Detection of nucleic acid hybrids
US6270973B1 (en) 1998-03-13 2001-08-07 Promega Corporation Multiplex method for nucleic acid detection
US6703211B1 (en) 1998-03-13 2004-03-09 Promega Corporation Cellular detection by providing high energy phosphate donor other than ADP to produce ATP
US7090975B2 (en) 1998-03-13 2006-08-15 Promega Corporation Pyrophosphorolysis and incorporation of nucleotide method for nucleic acid detection
DE19840897A1 (de) * 1998-09-08 2000-03-09 Dirk Happich Faktor V-Leiden-Test
US6703228B1 (en) * 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
EP1001037A3 (en) * 1998-09-28 2003-10-01 Whitehead Institute For Biomedical Research Pre-selection and isolation of single nucleotide polymorphisms
DE19848665A1 (de) * 1998-10-22 2000-04-27 Bayer Ag Ein automatisierbarer Schnelltest zum direkten Nachweis der APC Resistenz Mutation mit spezifischen Primern und Probes
EP1155150A1 (en) * 1999-02-18 2001-11-21 Promega Corporation Multiplex method for nucleic acid detection
US6238868B1 (en) * 1999-04-12 2001-05-29 Nanogen/Becton Dickinson Partnership Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification and bioelectronic chip technology
WO2000062036A1 (en) * 1999-04-12 2000-10-19 Nanogen/Becton Dickinson Partnership Amplification and separation of nucleic acid sequences using strand displacement amplification and bioelectronic microchip technology
US6582920B2 (en) * 2000-09-01 2003-06-24 Gen-Probe Incorporated Amplification of HIV-1 RT sequences for detection of sequences associated with drug-resistance mutations
EP1330549A2 (en) * 2000-10-27 2003-07-30 Abbott Laboratories Genotyping using partially-complementary probes
US6855509B2 (en) 2000-12-19 2005-02-15 Instrumentation Laboratory Company Protein S functional assay and kit therefor
WO2003076869A1 (en) * 2002-03-13 2003-09-18 Borealis Technology Oy Apparatus for inspecting deformation of pipes
US20030177850A1 (en) * 2002-03-19 2003-09-25 The Washington Post Company System and method for verifying the roll roundness of rolls of paper used for newspapers
US20050026168A1 (en) * 2002-12-13 2005-02-03 Genesis Group Inc. Method for the detection of risk factors associated with myocardial infarction
US20050032066A1 (en) * 2003-08-04 2005-02-10 Heng Chew Kiat Method for assessing risk of diseases with multiple contributing factors
FR2866349B1 (fr) * 2004-02-12 2008-05-16 Biomerieux Sa Procede de diagnostic/pronostic d'une thrombose
US20090004175A1 (en) * 2004-07-16 2009-01-01 Novo Nordick Health Care A/G Methods for Optimizing Forming Vlla-Based Hemostatic Treatment
EP1623996A1 (en) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved method of selecting a desired protein from a library
WO2006027111A1 (en) * 2004-09-06 2006-03-16 Zlb Behring Gmbh Modified coagulation factor viii with enhanced stability
KR100655658B1 (ko) * 2005-07-26 2006-12-08 삼성전자주식회사 게이트 전극 구조물과 그 제조 방법 및 이를 갖는 반도체트랜지스터와 그 제조 방법
US20110027184A1 (en) * 2006-01-12 2011-02-03 Russell James A Protein c pathway associated polymorphisms as response predictors to activated protein c or protein c-like compound administration
US20070207188A1 (en) * 2006-02-16 2007-09-06 Miller Debra L Cocoa products and methods of treating cardiovascular conditions with sugar-free cocoa
WO2008020090A1 (es) * 2006-08-18 2008-02-21 Laboratorios Indas, S.A. Método y kit para diagnosticar el riesgo de desarrollar una enfermedad trombótica venosa
US9717896B2 (en) 2007-12-18 2017-08-01 Gearbox, Llc Treatment indications informed by a priori implant information
US20090163856A1 (en) * 2007-12-19 2009-06-25 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Treatment indications informed by a prior implant information
US20090292214A1 (en) * 2008-05-22 2009-11-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Circulatory monitoring systems and methods
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US20090292213A1 (en) * 2008-05-21 2009-11-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Circulatory monitoring systems and methods
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Also Published As

Publication number Publication date
PT807691E (pt) 2002-04-29
JPH08509383A (ja) 1996-10-08
ATE206765T1 (de) 2001-10-15
EP0807691A3 (en) 1998-03-11
EP0696325A1 (en) 1996-02-14
CA2159907A1 (en) 1995-08-17
DE69523179T2 (de) 2002-06-06
ES2166948T3 (es) 2002-05-01
KR100384251B1 (ko) 2003-09-19
US6558913B1 (en) 2003-05-06
DE69523179D1 (de) 2001-11-15
ES2090001T3 (es) 1998-08-01
EP0696325B1 (en) 1998-05-13
JP3163105B2 (ja) 2001-05-08
EP0807691B1 (en) 2001-10-10
AU1809195A (en) 1995-08-29
WO1995021938A1 (en) 1995-08-17
JP2001242170A (ja) 2001-09-07
DE69502451D1 (de) 1998-06-18
KR960702007A (ko) 1996-03-28
GR960300034T1 (en) 1996-06-30
AU690644B2 (en) 1998-04-30
CA2159907C (en) 2006-12-12
GR3027579T3 (en) 1998-11-30
ES2090001T1 (es) 1996-10-16
EP0807691A2 (en) 1997-11-19
US6518016B1 (en) 2003-02-11
DK0696325T3 (da) 1999-03-01
DE69502451T2 (de) 1998-09-24
FI954855A (fi) 1995-11-17
ATE166110T1 (de) 1998-05-15
DE696325T1 (de) 1996-08-29
DK0807691T3 (da) 2002-02-04
US5910576A (en) 1999-06-08
JP3439458B2 (ja) 2003-08-25
FI954855A0 (fi) 1995-10-12

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