FI117470B - Separeringsförfarande och separeringsorgan - Google Patents
Separeringsförfarande och separeringsorgan Download PDFInfo
- Publication number
- FI117470B FI117470B FI956135A FI956135A FI117470B FI 117470 B FI117470 B FI 117470B FI 956135 A FI956135 A FI 956135A FI 956135 A FI956135 A FI 956135A FI 117470 B FI117470 B FI 117470B
- Authority
- FI
- Finland
- Prior art keywords
- magnetic
- solution
- separation
- particles
- magnet
- Prior art date
Links
- 239000002245 particle Substances 0.000 title claims abstract description 36
- 230000005291 magnetic effect Effects 0.000 title claims description 45
- 239000006249 magnetic particle Substances 0.000 title claims description 15
- 238000006243 chemical reaction Methods 0.000 title abstract description 6
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 4
- 238000000159 protein binding assay Methods 0.000 title 1
- 230000009870 specific binding Effects 0.000 title 1
- 239000007787 solid Substances 0.000 claims abstract 2
- 238000000926 separation method Methods 0.000 claims description 43
- 238000005192 partition Methods 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 4
- 210000000056 organ Anatomy 0.000 claims 8
- RYXPMWYHEBGTRV-UHFFFAOYSA-N Omeprazole sodium Chemical compound [Na+].N=1C2=CC(OC)=CC=C2[N-]C=1S(=O)CC1=NC=C(C)C(OC)=C1C RYXPMWYHEBGTRV-UHFFFAOYSA-N 0.000 claims 2
- 241000139712 Samla Species 0.000 claims 2
- 241001302210 Sida <water flea> Species 0.000 claims 1
- 239000013618 particulate matter Substances 0.000 claims 1
- 239000007790 solid phase Substances 0.000 abstract description 4
- 239000012491 analyte Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 description 7
- 238000005259 measurement Methods 0.000 description 5
- 239000011859 microparticle Substances 0.000 description 5
- BGPVFRJUHWVFKM-UHFFFAOYSA-N N1=C2C=CC=CC2=[N+]([O-])C1(CC1)CCC21N=C1C=CC=CC1=[N+]2[O-] Chemical compound N1=C2C=CC=CC2=[N+]([O-])C1(CC1)CCC21N=C1C=CC=CC1=[N+]2[O-] BGPVFRJUHWVFKM-UHFFFAOYSA-N 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 238000003018 immunoassay Methods 0.000 description 3
- 239000012620 biological material Substances 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000002238 attenuated effect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000005298 paramagnetic effect Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1048—General features of the devices using the transfer device for another function
- G01N2035/1055—General features of the devices using the transfer device for another function for immobilising reagents, e.g. dried reagents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/109—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Sampling And Sample Adjustment (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI956135A FI117470B (sv) | 1993-06-21 | 1995-12-20 | Separeringsförfarande och separeringsorgan |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI932866 | 1993-06-21 | ||
FI932866A FI932866A0 (fi) | 1993-06-21 | 1993-06-21 | Separeringsfoerfarande |
FI9400275 | 1994-06-20 | ||
PCT/FI1994/000275 WO1995000247A1 (en) | 1993-06-21 | 1994-06-20 | Separation method |
FI956135 | 1995-12-20 | ||
FI956135A FI117470B (sv) | 1993-06-21 | 1995-12-20 | Separeringsförfarande och separeringsorgan |
Publications (3)
Publication Number | Publication Date |
---|---|
FI956135A FI956135A (sv) | 1995-12-20 |
FI956135A0 FI956135A0 (sv) | 1995-12-20 |
FI117470B true FI117470B (sv) | 2006-10-31 |
Family
ID=8538179
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI932866A FI932866A0 (fi) | 1993-02-01 | 1993-06-21 | Separeringsfoerfarande |
FI956135A FI117470B (sv) | 1993-06-21 | 1995-12-20 | Separeringsförfarande och separeringsorgan |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI932866A FI932866A0 (fi) | 1993-02-01 | 1993-06-21 | Separeringsfoerfarande |
Country Status (8)
Country | Link |
---|---|
US (1) | US5647994A (sv) |
EP (1) | EP0737110B1 (sv) |
JP (1) | JP3254681B2 (sv) |
AU (1) | AU7074394A (sv) |
DE (1) | DE69420974T2 (sv) |
FI (2) | FI932866A0 (sv) |
NO (1) | NO309756B1 (sv) |
WO (1) | WO1995000247A1 (sv) |
Families Citing this family (129)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69434867T2 (de) | 1993-02-01 | 2007-05-16 | Thermo Electron Oy | Gerät zur Bestimmung eines Analyten in einer Probe |
FI930440A0 (fi) | 1993-02-01 | 1993-02-01 | Labsystems Oy | Bestaemningsfoerfarande |
JP3115501B2 (ja) * | 1994-06-15 | 2000-12-11 | プレシジョン・システム・サイエンス株式会社 | 分注機を利用した磁性体の脱着制御方法及びこの方法によって処理される各種装置 |
AU738171B2 (en) * | 1994-06-15 | 2001-09-13 | Precision System Science Co., Ltd. | Magnetic material attracting/releasing control method making use of a pipette device and various types of clinical inspection apparatus using the method |
US5837144A (en) * | 1994-06-16 | 1998-11-17 | Boehringer Mannheim Gmbh | Method of magnetically separating liquid components |
DE4423878A1 (de) * | 1994-07-07 | 1996-01-11 | Boehringer Mannheim Gmbh | Vorrichtung und Verfahren zum Abscheiden von magnetischen Mikropartikeln |
FI944939A0 (fi) * | 1994-10-20 | 1994-10-20 | Labsystems Oy | Foerfarande foer separering av partiklar |
FI944940A0 (fi) * | 1994-10-20 | 1994-10-20 | Labsystems Oy | Tvaofasigt separeringsfoerfarande |
FI944937A0 (fi) | 1994-10-20 | 1994-10-20 | Labsystems Oy | Separeringsanordning |
FI944938A0 (fi) * | 1994-10-20 | 1994-10-20 | Labsystems Oy | Foerflyttningsanordning |
WO1996029602A1 (fr) * | 1995-03-20 | 1996-09-26 | Precision System Science Co., Ltd. | Procede et dispositif pour le traitement de liquides a l'aide d'un distributeur |
US6048734A (en) | 1995-09-15 | 2000-04-11 | The Regents Of The University Of Michigan | Thermal microvalves in a fluid flow method |
DE69638151D1 (de) * | 1996-05-20 | 2010-04-29 | Prec System Science Co Ltd | Prozess und apparat zur kontrolle magnetischer teilchen mit hilfe einer pipettier-maschine |
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DE19730497C2 (de) * | 1997-07-16 | 2000-02-10 | Heermann Klaus Hinrich | Verfahren zum Waschen, zur Separierung und Konzentrierung von Biomolekülen unter Verwendung eines Magnetstifts |
IL123210A0 (en) * | 1998-02-06 | 1998-09-24 | Gombinsky Moshe | A device and system for the collection of magnetic particles |
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DE19963032A1 (de) | 1999-12-24 | 2001-06-28 | Roche Diagnostics Gmbh | System zur Bearbeitung von Proben in einer Mehrkammeranordnung |
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-
1993
- 1993-06-21 FI FI932866A patent/FI932866A0/fi not_active Application Discontinuation
-
1994
- 1994-06-20 JP JP50247895A patent/JP3254681B2/ja not_active Expired - Lifetime
- 1994-06-20 WO PCT/FI1994/000275 patent/WO1995000247A1/en active IP Right Grant
- 1994-06-20 US US08/553,600 patent/US5647994A/en not_active Expired - Lifetime
- 1994-06-20 DE DE69420974T patent/DE69420974T2/de not_active Expired - Lifetime
- 1994-06-20 AU AU70743/94A patent/AU7074394A/en not_active Abandoned
- 1994-06-20 EP EP94919683A patent/EP0737110B1/en not_active Expired - Lifetime
-
1995
- 1995-12-20 NO NO955200A patent/NO309756B1/no not_active IP Right Cessation
- 1995-12-20 FI FI956135A patent/FI117470B/sv not_active IP Right Cessation
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DE69420974T2 (de) | 2000-05-31 |
NO955200L (no) | 1995-12-20 |
FI956135A (sv) | 1995-12-20 |
WO1995000247A1 (en) | 1995-01-05 |
FI932866A0 (fi) | 1993-06-21 |
EP0737110B1 (en) | 1999-09-29 |
US5647994A (en) | 1997-07-15 |
FI956135A0 (sv) | 1995-12-20 |
JPH08511721A (ja) | 1996-12-10 |
NO309756B1 (no) | 2001-03-26 |
EP0737110A1 (en) | 1996-10-16 |
NO955200D0 (no) | 1995-12-20 |
JP3254681B2 (ja) | 2002-02-12 |
DE69420974D1 (de) | 1999-11-04 |
AU7074394A (en) | 1995-01-17 |
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