DE68916843T2 - Mikropartikel, Verfahren und Gerät zur Sammlung von Proben zur Verwendung bei der Markierung von Immunreaktionen und Verfahren und Gerät zur Bereitung von Proben. - Google Patents
Mikropartikel, Verfahren und Gerät zur Sammlung von Proben zur Verwendung bei der Markierung von Immunreaktionen und Verfahren und Gerät zur Bereitung von Proben.Info
- Publication number
- DE68916843T2 DE68916843T2 DE68916843T DE68916843T DE68916843T2 DE 68916843 T2 DE68916843 T2 DE 68916843T2 DE 68916843 T DE68916843 T DE 68916843T DE 68916843 T DE68916843 T DE 68916843T DE 68916843 T2 DE68916843 T2 DE 68916843T2
- Authority
- DE
- Germany
- Prior art keywords
- samples
- microparticles
- immune responses
- preparing
- collecting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00534—Mixing by a special element, e.g. stirrer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1048—General features of the devices using the transfer device for another function
- G01N2035/1055—General features of the devices using the transfer device for another function for immobilising reagents, e.g. dried reagents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2474/00—Immunochemical assays or immunoassays characterised by detection mode or means of detection
- G01N2474/20—Immunohistochemistry assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/971—Capture of complex after antigen-antibody reaction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/806—Electrical property or magnetic property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63102919A JPH01273584A (ja) | 1988-04-26 | 1988-04-26 | 検体捕集方法及び捕集装置 |
JP63156519A JPH01321362A (ja) | 1988-06-24 | 1988-06-24 | レーザ磁気免疫測定方法を実施するための検体調整方法 |
JP63272106A JP2567068B2 (ja) | 1988-10-28 | 1988-10-28 | 電子顕微鏡検体調整法及び電子顕微鏡検体調整器具 |
JP63307579A JPH02151767A (ja) | 1988-12-05 | 1988-12-05 | 磁性微粒子を免疫反応の標識に用いる検体調整法及び検体調整器具 |
JP1074245A JPH0721442B2 (ja) | 1989-03-27 | 1989-03-27 | 電子顕微鏡検体調整法及び電子顕微鏡検体調整器具 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68916843D1 DE68916843D1 (de) | 1994-08-25 |
DE68916843T2 true DE68916843T2 (de) | 1995-02-02 |
Family
ID=27524497
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68916843T Expired - Fee Related DE68916843T2 (de) | 1988-04-26 | 1989-04-26 | Mikropartikel, Verfahren und Gerät zur Sammlung von Proben zur Verwendung bei der Markierung von Immunreaktionen und Verfahren und Gerät zur Bereitung von Proben. |
Country Status (3)
Country | Link |
---|---|
US (2) | US5340749A (de) |
EP (1) | EP0339980B1 (de) |
DE (1) | DE68916843T2 (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5665582A (en) * | 1990-10-29 | 1997-09-09 | Dekalb Genetics Corp. | Isolation of biological materials |
JPH06510363A (ja) * | 1990-10-29 | 1994-11-17 | ディカルブ プラント ジェネティクス | 磁気性粒子を使用する生物学的材料の単離 |
JPH0792459B2 (ja) * | 1991-06-18 | 1995-10-09 | オリンパス光学工業株式会社 | 免疫学的試験方法 |
EP1130397B1 (de) * | 1993-02-01 | 2006-10-11 | Thermo Electron Oy | Gerät zur Bestimmung eines Analyten in einer Probe |
FI932866A0 (fi) * | 1993-06-21 | 1993-06-21 | Labsystems Oy | Separeringsfoerfarande |
EP0672458A3 (de) * | 1994-03-04 | 1996-02-28 | Cleveland Clinic Foundation | Verfahren und Vorrichtung zur magnetischen Zytometrie. |
US5602042A (en) * | 1994-04-14 | 1997-02-11 | Cytyc Corporation | Method and apparatus for magnetically separating biological particles from a mixture |
US5837144A (en) * | 1994-06-16 | 1998-11-17 | Boehringer Mannheim Gmbh | Method of magnetically separating liquid components |
DE4421058A1 (de) | 1994-06-16 | 1995-12-21 | Boehringer Mannheim Gmbh | Verfahren zur magnetischen Abtrennung von Flüssigkeitskomponenten |
DE4423878A1 (de) | 1994-07-07 | 1996-01-11 | Boehringer Mannheim Gmbh | Vorrichtung und Verfahren zum Abscheiden von magnetischen Mikropartikeln |
FI944937A0 (fi) | 1994-10-20 | 1994-10-20 | Labsystems Oy | Separeringsanordning |
US6919175B1 (en) | 1995-04-01 | 2005-07-19 | Roche Diagnostics Gmbh | System for releasing and isolating nucleic acids |
DE19512368A1 (de) * | 1995-04-01 | 1996-10-02 | Boehringer Mannheim Gmbh | System zur Freisetzung und Isolierung von Nukleinsäuren |
DE19520298A1 (de) * | 1995-06-02 | 1996-12-05 | Bayer Ag | Sortiervorrichtung für biologische Zellen oder Viren |
US5639669A (en) * | 1995-06-07 | 1997-06-17 | Ledley; Robert | Separation of fetal cells from maternal blood |
ATE284974T1 (de) | 1996-03-26 | 2005-01-15 | Cylex Inc | Verfahren zur messung der lymphozytenfunktion |
FR2748569B1 (fr) * | 1996-05-07 | 1998-08-07 | Biocom Sa | Procede et installation de separation de particules magnetiques dans un fluide pour l'analyse biologique, et application dudit procede |
EP0920627B1 (de) * | 1996-06-07 | 2004-05-12 | Immunivest Corporation | Magnetische trennung mit hilfe von externen und internen gradienten |
US6660159B1 (en) | 1996-06-07 | 2003-12-09 | Immunivest Corporation | Magnetic separation apparatus and methods |
US6790366B2 (en) * | 1996-06-07 | 2004-09-14 | Immunivest Corporation | Magnetic separation apparatus and methods |
US7666308B2 (en) * | 1996-06-07 | 2010-02-23 | Veridex, Llc. | Magnetic separation apparatus and methods |
US6136182A (en) * | 1996-06-07 | 2000-10-24 | Immunivest Corporation | Magnetic devices and sample chambers for examination and manipulation of cells |
US6890426B2 (en) * | 1996-06-07 | 2005-05-10 | Immunivest Corporation | Magnetic separation apparatus and methods |
US7169571B2 (en) | 1997-09-12 | 2007-01-30 | Cylex, Inc. | Methods for measurement of lymphocyte function |
US6241894B1 (en) * | 1997-10-10 | 2001-06-05 | Systemix | High gradient magnetic device and method for cell separation or purification |
DE69934449T2 (de) * | 1998-03-12 | 2007-09-27 | Miltenyi Biotech Gmbh | Mikrokolonnen-System für Magnettrennung |
DE19823719B4 (de) | 1998-05-27 | 2011-12-15 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren zum Aufkonzentrieren von Substanzen |
US7364921B1 (en) | 1999-01-06 | 2008-04-29 | University Of Medicine And Dentistry Of New Jersey | Method and apparatus for separating biological materials and other substances |
US6193892B1 (en) | 1999-03-03 | 2001-02-27 | Promega Corporation | Magnetic separation assembly and method |
US6672458B2 (en) * | 2000-05-19 | 2004-01-06 | Becton, Dickinson And Company | System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample |
KR20030066766A (ko) * | 2001-01-05 | 2003-08-09 | 이뮤니베스트 코포레이션 | 피사체를 이미지화하는 장치 및 방법 |
SE0100728D0 (sv) * | 2001-03-05 | 2001-03-05 | Sidec Technologies Ab Karolins | New method |
CN1488073A (zh) * | 2001-04-17 | 2004-04-07 | 西莱克斯公司 | 利用促细胞分裂原和抗原测定淋巴细胞活化的方法 |
US7169578B2 (en) * | 2001-07-27 | 2007-01-30 | Surface Logix, Inc. | Cell isolation and screening device and method of using same |
US7285412B2 (en) * | 2001-07-27 | 2007-10-23 | Surface Logix Inc. | Device for magnetic immobilization of cells |
US7169577B2 (en) * | 2001-07-27 | 2007-01-30 | Surface Logix, Inc. | Cell isolation and screening device and method of using same |
MXPA04001333A (es) * | 2001-08-13 | 2004-05-05 | Embrex Inc | Metodos para inyectar huevos de ave. |
US7241629B2 (en) * | 2001-12-20 | 2007-07-10 | Corning Incorporated | Detectable labels, methods of manufacture and use |
AU2003219759B2 (en) | 2002-02-14 | 2011-01-20 | Veridex, Llc | Methods and algorithms for cell enumeration in a low-cost cytometer |
US7764821B2 (en) * | 2002-02-14 | 2010-07-27 | Veridex, Llc | Methods and algorithms for cell enumeration in a low-cost cytometer |
JP2005522679A (ja) | 2002-04-12 | 2005-07-28 | インストゥルメンテイション ラボラトリー カンパニー | イムノアッセイプローブ |
KR100434690B1 (ko) * | 2002-07-19 | 2004-06-04 | 소광섭 | 생명체에 대한 자기장의 영향을 측정하는 장치 및 방법 |
US7601491B2 (en) * | 2003-02-06 | 2009-10-13 | Becton, Dickinson And Company | Pretreatment method for extraction of nucleic acid from biological samples and kits therefor |
US20040157219A1 (en) * | 2003-02-06 | 2004-08-12 | Jianrong Lou | Chemical treatment of biological samples for nucleic acid extraction and kits therefor |
US7282180B2 (en) * | 2003-07-02 | 2007-10-16 | Immunivest Corporation | Devices and methods to image objects |
US7390628B2 (en) * | 2003-12-23 | 2008-06-24 | University Of Florida Research Foundation, Inc. | Microparticle-based diagnostic methods |
US20050239091A1 (en) * | 2004-04-23 | 2005-10-27 | Collis Matthew P | Extraction of nucleic acids using small diameter magnetically-responsive particles |
US8211386B2 (en) | 2004-06-08 | 2012-07-03 | Biokit, S.A. | Tapered cuvette and method of collecting magnetic particles |
US8189899B2 (en) * | 2004-07-30 | 2012-05-29 | Veridex, Llc | Methods and algorithms for cell enumeration in a low-cost cytometer |
US20060024776A1 (en) * | 2004-08-02 | 2006-02-02 | Mcmillian Ray | Magnetic particle capture of whole intact organisms from clinical samples |
AU2005271687A1 (en) * | 2004-08-03 | 2006-02-16 | Becton, Dickinson And Company | Use of magnetic material to fractionate samples |
AU2005271688B2 (en) * | 2004-08-03 | 2011-10-06 | Becton, Dickinson And Company | Use of magnetic material to direct isolation of compounds and fractionation of multipart samples |
KR101229997B1 (ko) * | 2004-12-22 | 2013-02-06 | 톰 헨닝 요한센 | 고구배 자기장을 형성하는 방법 및 그에 기반한 물질 선별 장치 |
JP2009537021A (ja) * | 2006-05-12 | 2009-10-22 | ベリデックス・リミテッド・ライアビリティ・カンパニー | 蛍光顕微鏡法におけるレーザー照射システム |
WO2008036794A2 (en) * | 2006-09-22 | 2008-03-27 | Luminex Corporation | Assay preparation system |
US20090061497A1 (en) * | 2007-06-29 | 2009-03-05 | Becton, Dickinson And Company | Methods for Extraction and Purification of Components of Biological Samples |
US20110039280A1 (en) * | 2007-10-29 | 2011-02-17 | Purdue Research Foundation | Hybrid microfluidic spr and molecular imaging device |
US7927561B2 (en) | 2008-01-10 | 2011-04-19 | Becton, Dickinson And Company | Rapid particle detection assay |
JP5314317B2 (ja) * | 2008-04-08 | 2013-10-16 | 日本電子株式会社 | 検査方法及び試液 |
KR101067695B1 (ko) * | 2010-03-25 | 2011-09-27 | 충남대학교산학협력단 | 연자성 미세 구조물을 이용한 분자 이송 시스템 |
EP2683489A4 (de) * | 2011-03-11 | 2015-08-12 | Guisheng Yang | Vorrichtung und verfahren zur spülung von magnetteilchen |
KR101339923B1 (ko) * | 2011-11-03 | 2013-12-10 | 삼성전자주식회사 | 디스크 및 이를 포함하는 생체물질 검사장치 |
EP2951583B1 (de) | 2013-01-29 | 2018-01-24 | BIO-RAD Haifa Ltd. | Detektionsassays unter verwendung von magnetischen nanopartikeln |
USD766457S1 (en) * | 2014-08-20 | 2016-09-13 | Neurotar Ltd | Medical instrument, instrument and tool for laboratory use |
CN110220670B (zh) * | 2019-06-26 | 2021-12-10 | 河海大学 | 一种不扰动床面状态的野外泥沙运动试验装置 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3970518A (en) * | 1975-07-01 | 1976-07-20 | General Electric Company | Magnetic separation of biological particles |
US4157323A (en) * | 1976-06-09 | 1979-06-05 | California Institute Of Technology | Metal containing polymeric functional microspheres |
US4375407A (en) * | 1981-06-22 | 1983-03-01 | The Franklin Institute | High gradient magnetic separation device |
IL68507A (en) * | 1982-05-10 | 1986-01-31 | Univ Bar Ilan | System and methods for cell selection |
US4628037A (en) * | 1983-05-12 | 1986-12-09 | Advanced Magnetics, Inc. | Binding assays employing magnetic particles |
DE3522365A1 (de) * | 1985-06-22 | 1987-01-02 | Bayer Ag | Trenngeraet fuer magnetische partikel aus fluessiger phase |
US4710472A (en) * | 1985-09-25 | 1987-12-01 | The United States Of America As Represented By The Secretary Of The Navy | Magnetic separation device |
JP2509227B2 (ja) * | 1987-06-19 | 1996-06-19 | 日本電信電話株式会社 | レ−ザ磁気免疫測定装置 |
JPH0820450B2 (ja) * | 1987-07-24 | 1996-03-04 | 日本電信電話株式会社 | レ−ザ磁気免疫測定方法及び装置 |
JPH07122636B2 (ja) * | 1987-06-19 | 1995-12-25 | 日本電信電話株式会社 | レ−ザ磁気免疫測定装置 |
JPH07111429B2 (ja) * | 1986-09-22 | 1995-11-29 | 日本電信電話株式会社 | レ−ザ−磁気免疫測定法 |
WO1988002118A1 (en) * | 1986-09-22 | 1988-03-24 | Nippon Telegraph And Telephone Corporation | Laser magnetic immunoassay method and apparatus therefor |
JPS63106559A (ja) * | 1986-10-23 | 1988-05-11 | Nippon Telegr & Teleph Corp <Ntt> | レ−ザ磁気免疫測定方法及び装置 |
JPS63188764A (ja) * | 1987-02-02 | 1988-08-04 | Nippon Telegr & Teleph Corp <Ntt> | レ−ザ磁気免疫測定方法のための検体容器並びに該検体容器を用いた検体の調製方法 |
JP2502546B2 (ja) * | 1986-10-25 | 1996-05-29 | 日本電信電話株式会社 | レ−ザ磁気免疫測定方法 |
JPS63188766A (ja) * | 1987-02-02 | 1988-08-04 | Nippon Telegr & Teleph Corp <Ntt> | レ−ザ磁気免疫測定法および測定装置 |
JPH07111428B2 (ja) * | 1987-10-20 | 1995-11-29 | 日本電信電話株式会社 | レーザ磁気免疫測定方法及び測定装置 |
JPH07111430B2 (ja) * | 1987-10-22 | 1995-11-29 | 日本電信電話株式会社 | レーザ磁気免疫測定方法及び測定装置 |
-
1989
- 1989-04-26 EP EP89304171A patent/EP0339980B1/de not_active Expired - Lifetime
- 1989-04-26 DE DE68916843T patent/DE68916843T2/de not_active Expired - Fee Related
-
1992
- 1992-12-17 US US07/991,507 patent/US5340749A/en not_active Expired - Fee Related
-
1994
- 1994-05-25 US US08/249,152 patent/US5498550A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE68916843D1 (de) | 1994-08-25 |
US5340749A (en) | 1994-08-23 |
EP0339980B1 (de) | 1994-07-20 |
US5498550A (en) | 1996-03-12 |
EP0339980A1 (de) | 1989-11-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |