FI116940B - Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet - Google Patents
Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet Download PDFInfo
- Publication number
- FI116940B FI116940B FI20011560A FI20011560A FI116940B FI 116940 B FI116940 B FI 116940B FI 20011560 A FI20011560 A FI 20011560A FI 20011560 A FI20011560 A FI 20011560A FI 116940 B FI116940 B FI 116940B
- Authority
- FI
- Finland
- Prior art keywords
- benzenesulfonamide
- dimethylpyrimidin
- alkoxy
- compound
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/69—Benzenesulfonamido-pyrimidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20011560A FI116940B (fi) | 2001-07-20 | 2001-07-20 | Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet |
| ARP020102661A AR036173A1 (es) | 2001-07-20 | 2002-07-16 | Compuesto de bencenosulfonamida y su uso en la elaboracion de una preparacion util para el tratamiento o la prevencion de una enfermedad mediada por el alfa-2b-adrenoceptor |
| US10/196,123 US6767909B2 (en) | 2001-07-20 | 2002-07-17 | Compounds useful for treatment or prevention of disease mediated by alpha-2B-adrenoceptor |
| PE2002000634A PE20030587A1 (es) | 2001-07-20 | 2002-07-17 | DERIVADOS DE PIRIMIDINA BENCENOSULFONAMIDA COMO ANTAGONISTAS DE ALFA-2ß-ADRENORECEPTOR |
| PCT/FI2002/000643 WO2003008387A1 (en) | 2001-07-20 | 2002-07-22 | Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor |
| RU2004105035/04A RU2004105035A (ru) | 2001-07-20 | 2002-07-22 | Соединения, полезные для лечения или профилактики заболевания, опосредованного альфа-2b-адреноцептором |
| PL02367040A PL367040A1 (en) | 2001-07-20 | 2002-07-22 | Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor |
| NZ530366A NZ530366A (en) | 2001-07-20 | 2002-07-22 | Compounds useful for treatment or prevention of disease mediated by alpha-2B-adrenoceptor |
| MXPA04000615A MXPA04000615A (es) | 2001-07-20 | 2002-07-22 | Compuestos utiles para el tratamiento o la prevencion de enfermedades mediadas por alfa-2b-adrenoceptor. |
| CNA02814595XA CN1753877A (zh) | 2001-07-20 | 2002-07-22 | 用于治疗或预防α－2B－肾上腺素受体介导疾病的化合物 |
| HU0401076A HUP0401076A2 (hu) | 2001-07-20 | 2002-07-22 | Alfa-2B-andrenoceptor antagonista vegyületek és alkalmazásuk gyógyszerkészítmények előállítására |
| EP02748902A EP1417182A1 (en) | 2001-07-20 | 2002-07-22 | Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor |
| KR10-2004-7001043A KR20040030850A (ko) | 2001-07-20 | 2002-07-22 | 알파-2비-아드레노셉터 매개 질병의 치료 및 예방에유용한 화합물 |
| JP2003513947A JP2004535467A (ja) | 2001-07-20 | 2002-07-22 | α−２Ｂ−アドレナリン受容体が介在する疾患を治療又は予防するために有用な化合物 |
| IL15951102A IL159511A0 (en) | 2001-07-20 | 2002-07-22 | Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor |
| CA002454187A CA2454187A1 (en) | 2001-07-20 | 2002-07-22 | Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor |
| NO20040237A NO20040237L (no) | 2001-07-20 | 2004-01-19 | Forbindelser anvendelige for behandling eller forbygging av sykdom overført via alfa-2B-adrenoceptor |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20011560A FI116940B (fi) | 2001-07-20 | 2001-07-20 | Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet |
| FI20011560 | 2001-07-20 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI20011560A0 FI20011560A0 (fi) | 2001-07-20 |
| FI20011560A FI20011560A (fi) | 2003-01-21 |
| FI116940B true FI116940B (fi) | 2006-04-13 |
Family
ID=8561670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20011560A FI116940B (fi) | 2001-07-20 | 2001-07-20 | Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6767909B2 (zh) |
| KR (1) | KR20040030850A (zh) |
| CN (1) | CN1753877A (zh) |
| AR (1) | AR036173A1 (zh) |
| FI (1) | FI116940B (zh) |
| PE (1) | PE20030587A1 (zh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2332912A1 (en) * | 2003-08-08 | 2011-06-15 | Vertex Pharmaceuticals Incorporated | Heteroarylaminosulfonylphenylderivates for use as sodium or calcium channel blockers in the treatment of pain |
| US7615563B2 (en) * | 2003-08-08 | 2009-11-10 | Gonzalez Iii Jesus E | Compositions useful as inhibitors of voltage-gated sodium channels |
| FI118265B (fi) * | 2004-01-15 | 2007-09-14 | Jurilab Ltd Oy | Menetelmä akuutin sydäninfarktin ja sepelvaltimotaudin riskin havaitsemiseksi |
| CA2668859A1 (en) | 2006-11-07 | 2008-05-15 | Proteologics Ltd. | Pyrimidine derivatives as posh and posh-ap inhibitors |
| ES2968371T3 (es) | 2013-10-10 | 2024-05-09 | Eastern Virginia Medical School | Derivados de 4-((2-hidroxi-3-metoxibencil)amino) bencenosulfonamida como inhibidores de la 12-lipoxigenasa |
| CN104189909B (zh) * | 2014-09-18 | 2017-04-12 | 中国人民解放军第三军医大学 | 肾上腺素受体拮抗剂在制备缓解脑损伤引起钠电流增加的药物中应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2086544C1 (ru) | 1991-06-13 | 1997-08-10 | Хоффманн-Ля Рош АГ | Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина |
| US6150389A (en) | 1994-07-11 | 2000-11-21 | Allergan Sales, Inc. | Comformationally rigid bicyclic and adamantane derivatives useful as α2 -adrenergic blocking agents |
| US6521632B2 (en) | 2000-02-11 | 2003-02-18 | Oy Juvantia Pharma Ltd | Method for the treatment or prevention of a disease mediated by the alpha-2B-adrenoceptor |
| NZ520500A (en) | 2000-02-11 | 2005-01-28 | Juvantia Pharma Ltd Oy | Sulfonamides useful for the treatment or prevention of a disease i.e. vascular and coronary heart disease mediated by the alpha-2B-adrenoceptor |
-
2001
- 2001-07-20 FI FI20011560A patent/FI116940B/fi not_active IP Right Cessation
-
2002
- 2002-07-16 AR ARP020102661A patent/AR036173A1/es unknown
- 2002-07-17 PE PE2002000634A patent/PE20030587A1/es not_active Application Discontinuation
- 2002-07-17 US US10/196,123 patent/US6767909B2/en not_active Expired - Fee Related
- 2002-07-22 CN CNA02814595XA patent/CN1753877A/zh active Pending
- 2002-07-22 KR KR10-2004-7001043A patent/KR20040030850A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20030073710A1 (en) | 2003-04-17 |
| FI20011560A0 (fi) | 2001-07-20 |
| CN1753877A (zh) | 2006-03-29 |
| US6767909B2 (en) | 2004-07-27 |
| FI20011560A (fi) | 2003-01-21 |
| KR20040030850A (ko) | 2004-04-09 |
| PE20030587A1 (es) | 2003-07-08 |
| AR036173A1 (es) | 2004-08-18 |
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| FG | Patent granted |
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| MA | Patent expired |