FI20011560A0 - Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet - Google Patents

Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet

Info

Publication number
FI20011560A0
FI20011560A0 FI20011560A FI20011560A FI20011560A0 FI 20011560 A0 FI20011560 A0 FI 20011560A0 FI 20011560 A FI20011560 A FI 20011560A FI 20011560 A FI20011560 A FI 20011560A FI 20011560 A0 FI20011560 A0 FI 20011560A0
Authority
FI
Finland
Prior art keywords
alpha
prevention
treatment
compounds useful
mediated disease
Prior art date
Application number
FI20011560A
Other languages
English (en)
Swedish (sv)
Other versions
FI20011560A (fi
FI116940B (fi
Inventor
Topi Joutsamo
Andrei Yurievitch Tauber
Harri Salo
Anna-Marja Hoffren
Siegfried Wurster
Original Assignee
Juvantia Pharma Ltd Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Juvantia Pharma Ltd Oy filed Critical Juvantia Pharma Ltd Oy
Publication of FI20011560A0 publication Critical patent/FI20011560A0/fi
Priority to FI20011560A priority Critical patent/FI116940B/fi
Priority to ARP020102661A priority patent/AR036173A1/es
Priority to PE2002000634A priority patent/PE20030587A1/es
Priority to US10/196,123 priority patent/US6767909B2/en
Priority to PL02367040A priority patent/PL367040A1/xx
Priority to PCT/FI2002/000643 priority patent/WO2003008387A1/en
Priority to HU0401076A priority patent/HUP0401076A2/hu
Priority to KR10-2004-7001043A priority patent/KR20040030850A/ko
Priority to MXPA04000615A priority patent/MXPA04000615A/es
Priority to CNA02814595XA priority patent/CN1753877A/zh
Priority to EP02748902A priority patent/EP1417182A1/en
Priority to IL15951102A priority patent/IL159511A0/xx
Priority to NZ530366A priority patent/NZ530366A/en
Priority to RU2004105035/04A priority patent/RU2004105035A/ru
Priority to CA002454187A priority patent/CA2454187A1/en
Priority to JP2003513947A priority patent/JP2004535467A/ja
Publication of FI20011560A publication Critical patent/FI20011560A/fi
Priority to NO20040237A priority patent/NO20040237L/no
Application granted granted Critical
Publication of FI116940B publication Critical patent/FI116940B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69Benzenesulfonamido-pyrimidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
FI20011560A 2001-07-20 2001-07-20 Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet FI116940B (fi)

Priority Applications (17)

Application Number Priority Date Filing Date Title
FI20011560A FI116940B (fi) 2001-07-20 2001-07-20 Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet
ARP020102661A AR036173A1 (es) 2001-07-20 2002-07-16 Compuesto de bencenosulfonamida y su uso en la elaboracion de una preparacion util para el tratamiento o la prevencion de una enfermedad mediada por el alfa-2b-adrenoceptor
PE2002000634A PE20030587A1 (es) 2001-07-20 2002-07-17 DERIVADOS DE PIRIMIDINA BENCENOSULFONAMIDA COMO ANTAGONISTAS DE ALFA-2ß-ADRENORECEPTOR
US10/196,123 US6767909B2 (en) 2001-07-20 2002-07-17 Compounds useful for treatment or prevention of disease mediated by alpha-2B-adrenoceptor
MXPA04000615A MXPA04000615A (es) 2001-07-20 2002-07-22 Compuestos utiles para el tratamiento o la prevencion de enfermedades mediadas por alfa-2b-adrenoceptor.
IL15951102A IL159511A0 (en) 2001-07-20 2002-07-22 Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor
HU0401076A HUP0401076A2 (hu) 2001-07-20 2002-07-22 Alfa-2B-andrenoceptor antagonista vegyületek és alkalmazásuk gyógyszerkészítmények előállítására
KR10-2004-7001043A KR20040030850A (ko) 2001-07-20 2002-07-22 알파-2비-아드레노셉터 매개 질병의 치료 및 예방에유용한 화합물
PL02367040A PL367040A1 (en) 2001-07-20 2002-07-22 Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor
CNA02814595XA CN1753877A (zh) 2001-07-20 2002-07-22 用于治疗或预防α-2B-肾上腺素受体介导疾病的化合物
EP02748902A EP1417182A1 (en) 2001-07-20 2002-07-22 Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor
PCT/FI2002/000643 WO2003008387A1 (en) 2001-07-20 2002-07-22 Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor
NZ530366A NZ530366A (en) 2001-07-20 2002-07-22 Compounds useful for treatment or prevention of disease mediated by alpha-2B-adrenoceptor
RU2004105035/04A RU2004105035A (ru) 2001-07-20 2002-07-22 Соединения, полезные для лечения или профилактики заболевания, опосредованного альфа-2b-адреноцептором
CA002454187A CA2454187A1 (en) 2001-07-20 2002-07-22 Compounds useful for treatment or prevention of disease mediated by alpha-2b-adrenoceptor
JP2003513947A JP2004535467A (ja) 2001-07-20 2002-07-22 α−2B−アドレナリン受容体が介在する疾患を治療又は予防するために有用な化合物
NO20040237A NO20040237L (no) 2001-07-20 2004-01-19 Forbindelser anvendelige for behandling eller forbygging av sykdom overført via alfa-2B-adrenoceptor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20011560A FI116940B (fi) 2001-07-20 2001-07-20 Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet
FI20011560 2001-07-20

Publications (3)

Publication Number Publication Date
FI20011560A0 true FI20011560A0 (fi) 2001-07-20
FI20011560A FI20011560A (fi) 2003-01-21
FI116940B FI116940B (fi) 2006-04-13

Family

ID=8561670

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20011560A FI116940B (fi) 2001-07-20 2001-07-20 Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet

Country Status (6)

Country Link
US (1) US6767909B2 (fi)
KR (1) KR20040030850A (fi)
CN (1) CN1753877A (fi)
AR (1) AR036173A1 (fi)
FI (1) FI116940B (fi)
PE (1) PE20030587A1 (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7615563B2 (en) * 2003-08-08 2009-11-10 Gonzalez Iii Jesus E Compositions useful as inhibitors of voltage-gated sodium channels
JP2007501804A (ja) * 2003-08-08 2007-02-01 バーテックス ファーマシューティカルズ インコーポレイテッド 電位開口型のナトリウムチャネルのインヒビターとして有用な組成物
FI118265B (fi) * 2004-01-15 2007-09-14 Jurilab Ltd Oy Menetelmä akuutin sydäninfarktin ja sepelvaltimotaudin riskin havaitsemiseksi
AU2007318922C1 (en) 2006-11-07 2013-09-12 Proteologics Ltd. Pyrimidine derivatives as POSH and POSH-AP inhibitors
CA2926950C (en) 2013-10-10 2022-10-11 Eastern Virginia Medical School 4-((2-hydroxy-3-methoxybenzyl)amino) benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase
CN104189909B (zh) * 2014-09-18 2017-04-12 中国人民解放军第三军医大学 肾上腺素受体拮抗剂在制备缓解脑损伤引起钠电流增加的药物中应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2086544C1 (ru) 1991-06-13 1997-08-10 Хоффманн-Ля Рош АГ Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина
US6150389A (en) 1994-07-11 2000-11-21 Allergan Sales, Inc. Comformationally rigid bicyclic and adamantane derivatives useful as α2 -adrenergic blocking agents
PL357872A1 (en) 2000-02-11 2004-07-26 Oy Juvantia Pharma Ltd Compounds useful for the treatment or prevention of a disease mediated by the alpha-2b-adrenoceptor
US6521632B2 (en) 2000-02-11 2003-02-18 Oy Juvantia Pharma Ltd Method for the treatment or prevention of a disease mediated by the alpha-2B-adrenoceptor

Also Published As

Publication number Publication date
PE20030587A1 (es) 2003-07-08
FI20011560A (fi) 2003-01-21
FI116940B (fi) 2006-04-13
AR036173A1 (es) 2004-08-18
KR20040030850A (ko) 2004-04-09
US6767909B2 (en) 2004-07-27
US20030073710A1 (en) 2003-04-17
CN1753877A (zh) 2006-03-29

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