FI114705B - Kinolonijohdannainen virtsainkontinenssin hoitoon - Google Patents
Kinolonijohdannainen virtsainkontinenssin hoitoon Download PDFInfo
- Publication number
- FI114705B FI114705B FI964019A FI964019A FI114705B FI 114705 B FI114705 B FI 114705B FI 964019 A FI964019 A FI 964019A FI 964019 A FI964019 A FI 964019A FI 114705 B FI114705 B FI 114705B
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- FI
- Finland
- Prior art keywords
- compound
- cyanophenyl
- trifluoromethyl
- att
- formula
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- 206010046543 Urinary incontinence Diseases 0.000 title claims abstract description 16
- 238000011282 treatment Methods 0.000 title claims description 12
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- 238000000034 method Methods 0.000 claims abstract description 32
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 25
- -1 3-cyanophenyl Chemical group 0.000 claims description 24
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 claims description 18
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- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims description 5
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- WEXRUCMBJFQVBZ-UHFFFAOYSA-N pentobarbital Chemical compound CCCC(C)C1(CC)C(=O)NC(=O)NC1=O WEXRUCMBJFQVBZ-UHFFFAOYSA-N 0.000 description 1
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- DDBREPKUVSBGFI-UHFFFAOYSA-N phenobarbital Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NC(=O)NC1=O DDBREPKUVSBGFI-UHFFFAOYSA-N 0.000 description 1
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- DJXNJVFEFSWHLY-UHFFFAOYSA-N quinoline-3-carboxylic acid Chemical compound C1=CC=CC2=CC(C(=O)O)=CN=C21 DJXNJVFEFSWHLY-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9407432 | 1994-04-14 | ||
| GB9407432A GB9407432D0 (en) | 1994-04-14 | 1994-04-14 | Heterocyclic derivative |
| PCT/GB1995/000845 WO1995028388A1 (en) | 1994-04-14 | 1995-04-13 | Quinolone derivative for treatment of urinary incontinence |
| GB9500845 | 1995-04-13 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI964019A0 FI964019A0 (fi) | 1996-10-07 |
| FI964019L FI964019L (fi) | 1996-10-07 |
| FI114705B true FI114705B (fi) | 2004-12-15 |
Family
ID=10753541
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI964019A FI114705B (fi) | 1994-04-14 | 1996-10-07 | Kinolonijohdannainen virtsainkontinenssin hoitoon |
| FI20040352A FI115630B (fi) | 1994-04-14 | 2004-03-04 | Menetelmä 4-(3-syaanifenyyli)-trifluorimetyyli-5-okso-1,4,5,6,7,8-heksahydrokinoliini-3-karboksyylihapon valmistamiseksi |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20040352A FI115630B (fi) | 1994-04-14 | 2004-03-04 | Menetelmä 4-(3-syaanifenyyli)-trifluorimetyyli-5-okso-1,4,5,6,7,8-heksahydrokinoliini-3-karboksyylihapon valmistamiseksi |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0755382B1 (de) |
| JP (1) | JP3782445B2 (de) |
| KR (1) | KR100344885B1 (de) |
| CN (1) | CN1058708C (de) |
| AT (1) | ATE202089T1 (de) |
| AU (1) | AU700773B2 (de) |
| BR (1) | BR9507366A (de) |
| CA (1) | CA2187525C (de) |
| CZ (1) | CZ284652B6 (de) |
| DE (1) | DE69521310T2 (de) |
| DK (1) | DK0755382T3 (de) |
| ES (1) | ES2159633T3 (de) |
| FI (2) | FI114705B (de) |
| GB (1) | GB9407432D0 (de) |
| GR (1) | GR3036482T3 (de) |
| HU (1) | HU215387B (de) |
| MX (1) | MX9603920A (de) |
| NO (1) | NO307177B1 (de) |
| NZ (1) | NZ283779A (de) |
| PL (2) | PL183095B1 (de) |
| PT (1) | PT755382E (de) |
| RU (1) | RU2149870C1 (de) |
| SK (1) | SK281124B6 (de) |
| WO (1) | WO1995028388A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2378936A1 (en) * | 1999-08-03 | 2001-02-08 | Abbott Laboratories | Potassium channel openers |
| JP2004505109A (ja) * | 2000-08-02 | 2004-02-19 | アストラゼネカ・アクチエボラーグ | 置換された１，４−ジヒドロピリジンの不斉合成法 |
| SE0200205D0 (sv) | 2002-01-24 | 2002-01-24 | Astrazeneca Ab | Method |
| UA92008C2 (en) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY |
| UA92009C2 (ru) * | 2005-05-04 | 2010-09-27 | Н.В. Органон | Производные 4-фенил-5-оксо-1,4,5,6,7,8-гексагидрохинолина для лечения бесплодия |
| CN102532015B (zh) * | 2012-01-18 | 2013-10-23 | 云南大学 | 香豆素及其类似物的固相合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2003148A1 (de) * | 1970-01-24 | 1971-07-29 | Bayer Ag | Neue 1,4-Dihydropyridinderivate |
| SU435237A1 (ru) * | 1972-08-08 | 1974-07-05 | Ордена Трудового Красного Знамени институт химических наук | Способ получения производных 5-кето-5,6,7,8-тетрагидрохинолина |
| GB1432379A (en) * | 1973-07-12 | 1976-04-14 | Wyeth John & Brother Ltd | Preparation of quinoline derivatives |
| GB1465651A (en) * | 1974-04-19 | 1977-02-23 | Wyeth John & Brother Ltd | Carbocyclic-fused ring pyridine derivatives |
| GB9220570D0 (en) * | 1991-10-21 | 1992-11-11 | Ici Plc | Therapeutic agent |
| GB9318935D0 (en) * | 1992-10-20 | 1993-10-27 | Zeneca Ltd | Heterocyclic derivatives |
-
1994
- 1994-04-14 GB GB9407432A patent/GB9407432D0/en active Pending
-
1995
- 1995-04-13 CN CN95192577A patent/CN1058708C/zh not_active Expired - Fee Related
- 1995-04-13 RU RU96119966/04A patent/RU2149870C1/ru active
- 1995-04-13 MX MX9603920A patent/MX9603920A/es not_active IP Right Cessation
- 1995-04-13 CA CA002187525A patent/CA2187525C/en not_active Expired - Fee Related
- 1995-04-13 PL PL95343448A patent/PL183095B1/pl not_active IP Right Cessation
- 1995-04-13 KR KR1019960705672A patent/KR100344885B1/ko not_active Expired - Fee Related
- 1995-04-13 EP EP95915256A patent/EP0755382B1/de not_active Expired - Lifetime
- 1995-04-13 NZ NZ283779A patent/NZ283779A/en not_active IP Right Cessation
- 1995-04-13 HU HU9602747A patent/HU215387B/hu not_active IP Right Cessation
- 1995-04-13 JP JP52680695A patent/JP3782445B2/ja not_active Expired - Fee Related
- 1995-04-13 AT AT95915256T patent/ATE202089T1/de not_active IP Right Cessation
- 1995-04-13 DE DE69521310T patent/DE69521310T2/de not_active Expired - Fee Related
- 1995-04-13 SK SK1317-96A patent/SK281124B6/sk not_active IP Right Cessation
- 1995-04-13 PL PL95316790A patent/PL182031B1/pl not_active IP Right Cessation
- 1995-04-13 PT PT95915256T patent/PT755382E/pt unknown
- 1995-04-13 WO PCT/GB1995/000845 patent/WO1995028388A1/en not_active Ceased
- 1995-04-13 DK DK95915256T patent/DK0755382T3/da active
- 1995-04-13 CZ CZ962981A patent/CZ284652B6/cs not_active IP Right Cessation
- 1995-04-13 AU AU22199/95A patent/AU700773B2/en not_active Ceased
- 1995-04-13 BR BR9507366A patent/BR9507366A/pt not_active IP Right Cessation
- 1995-04-13 ES ES95915256T patent/ES2159633T3/es not_active Expired - Lifetime
-
1996
- 1996-10-07 FI FI964019A patent/FI114705B/fi active
- 1996-10-11 NO NO964345A patent/NO307177B1/no not_active IP Right Cessation
-
2001
- 2001-08-31 GR GR20010401341T patent/GR3036482T3/el not_active IP Right Cessation
-
2004
- 2004-03-04 FI FI20040352A patent/FI115630B/fi active IP Right Grant
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