FI112321B - Menetelmä (S)-timololihemihydraattia sisältävän oftalmisen tooppisen koostumuksen valmistamiseksi - Google Patents

Menetelmä (S)-timololihemihydraattia sisältävän oftalmisen tooppisen koostumuksen valmistamiseksi Download PDF

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Publication number
FI112321B
FI112321B FI950050A FI950050A FI112321B FI 112321 B FI112321 B FI 112321B FI 950050 A FI950050 A FI 950050A FI 950050 A FI950050 A FI 950050A FI 112321 B FI112321 B FI 112321B
Authority
FI
Finland
Prior art keywords
composition
hemihydrate
process according
butylamino
morpholino
Prior art date
Application number
FI950050A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI950050A (fi
FI950050A0 (fi
Inventor
Esko Pohjala
Jarkko Ruohonen
Markku Peraelampi
Kari Lehmussaari
Olli Oksala
Timo Reunamaeki
Original Assignee
Santen Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharma Co Ltd filed Critical Santen Pharma Co Ltd
Priority to FI950050A priority Critical patent/FI112321B/fi
Publication of FI950050A publication Critical patent/FI950050A/fi
Publication of FI950050A0 publication Critical patent/FI950050A0/fi
Application granted granted Critical
Publication of FI112321B publication Critical patent/FI112321B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI950050A 1992-07-08 1995-01-04 Menetelmä (S)-timololihemihydraattia sisältävän oftalmisen tooppisen koostumuksen valmistamiseksi FI112321B (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI950050A FI112321B (fi) 1992-07-08 1995-01-04 Menetelmä (S)-timololihemihydraattia sisältävän oftalmisen tooppisen koostumuksen valmistamiseksi

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US91066592A 1992-07-08 1992-07-08
US91066592 1992-07-08
PCT/FI1993/000269 WO1994001115A1 (en) 1992-07-08 1993-06-23 Ophthalmic topical composition containing (s)-timolol hemihydrate
FI9300269 1993-06-23
FI950050A FI112321B (fi) 1992-07-08 1995-01-04 Menetelmä (S)-timololihemihydraattia sisältävän oftalmisen tooppisen koostumuksen valmistamiseksi
FI950050 1995-01-04

Publications (3)

Publication Number Publication Date
FI950050A FI950050A (fi) 1995-01-04
FI950050A0 FI950050A0 (fi) 1995-01-04
FI112321B true FI112321B (fi) 2003-11-28

Family

ID=25429138

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950050A FI112321B (fi) 1992-07-08 1995-01-04 Menetelmä (S)-timololihemihydraattia sisältävän oftalmisen tooppisen koostumuksen valmistamiseksi

Country Status (21)

Country Link
EP (1) EP0577913B1 (hu)
JP (1) JP3094233B2 (hu)
KR (1) KR100278851B1 (hu)
AT (1) ATE154513T1 (hu)
AU (1) AU678972B2 (hu)
BR (1) BR9306800A (hu)
CA (1) CA2139781C (hu)
CZ (1) CZ282168B6 (hu)
DE (1) DE69220484T2 (hu)
DK (1) DK0577913T3 (hu)
EE (1) EE03078B1 (hu)
ES (1) ES2106852T3 (hu)
FI (1) FI112321B (hu)
GR (1) GR3024648T3 (hu)
HK (1) HK1007503A1 (hu)
HU (1) HU221618B1 (hu)
NO (1) NO306535B1 (hu)
NZ (1) NZ253164A (hu)
PL (1) PL172503B1 (hu)
SG (1) SG49770A1 (hu)
WO (1) WO1994001115A1 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2270119A1 (en) * 1996-10-28 1998-05-07 Senju Pharmaceutical Co., Ltd. Drugs for ameliorating ocular circulatory disorders
IT1298758B1 (it) * 1998-03-19 2000-02-02 Angelini Ricerche Spa Soluzione umettante e lubrificante per uso oftalmico
UA72207C2 (uk) * 1998-04-07 2005-02-15 Брістол- Майєрс Сквібб Фарма Компані Фармацевтична композиція ефавіренцу з добавкою дезінтегруючих агентів у вигляді швидкорозчинних капсул або таблеток та спосіб її виготовлення
WO2004098592A1 (ja) * 2003-05-06 2004-11-18 Senju Pharmaceutical Co. Ltd. オキサゾリジノン誘導体含有組成物
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
JP2014024794A (ja) * 2012-07-27 2014-02-06 Nippon Tenganyaku Kenkyusho:Kk チモロールまたはその薬学的に許容される塩を含有する水性組成物およびその光安定化方法
GR1008483B (el) * 2013-12-23 2015-05-12 Rafarm Α.Ε.Β.Ε., Οφθαλμικη φαρμακευτικη συνθεση και μεθοδος για την παρασκευη αυτης

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195085A (en) 1975-09-26 1980-03-25 Merck & Co., Inc. Compositions and methods for treating glaucoma by the topical administration of t-butylamino-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy-2-phopanol hydrogen maleate
NZ196227A (en) * 1980-02-19 1984-09-28 Merck & Co Inc 1,2,5-thiadiazole derivative and ophthalmic compositions
US4752478A (en) * 1984-12-17 1988-06-21 Merck & Co., Inc. Transdermal system for timolol
GB8822285D0 (en) * 1988-09-22 1988-10-26 Ddsa Pharmaceuticals Ltd Opthalmic preparations
FI82240C (fi) 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.

Also Published As

Publication number Publication date
CZ282168B6 (cs) 1997-05-14
HUT72657A (en) 1996-05-28
NO950059D0 (no) 1995-01-06
NO950059L (no) 1995-01-06
CA2139781C (en) 2003-09-23
DE69220484T2 (de) 1998-02-05
SG49770A1 (en) 1998-06-15
DE69220484D1 (de) 1997-07-24
EP0577913B1 (en) 1997-06-18
JPH07508745A (ja) 1995-09-28
JP3094233B2 (ja) 2000-10-03
AU678972B2 (en) 1997-06-19
HK1007503A1 (en) 1999-04-16
NZ253164A (en) 1996-01-26
AU4329693A (en) 1994-01-31
EE03078B1 (et) 1998-04-15
NO306535B1 (no) 1999-11-22
PL307051A1 (en) 1995-05-02
KR950702422A (ko) 1995-07-29
ATE154513T1 (de) 1997-07-15
EP0577913A1 (en) 1994-01-12
DK0577913T3 (da) 1998-01-26
HU221618B1 (hu) 2002-12-28
CZ4495A3 (en) 1995-09-13
CA2139781A1 (en) 1994-01-20
HU9500035D0 (en) 1995-03-28
WO1994001115A1 (en) 1994-01-20
PL172503B1 (pl) 1997-10-31
ES2106852T3 (es) 1997-11-16
FI950050A (fi) 1995-01-04
KR100278851B1 (ko) 2001-01-15
GR3024648T3 (en) 1997-12-31
FI950050A0 (fi) 1995-01-04
BR9306800A (pt) 1998-12-08

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: SANTEN OY

HC Name/ company changed in application

Owner name: RECHERCHE D.C.B.L/D.C.B.L. RESEARCH INC.