FI112116B - Menetelmä proteiinin 3-ulotteisen rakenneinformaation määrittämiseksi ja ravintoväliaine - Google Patents

Menetelmä proteiinin 3-ulotteisen rakenneinformaation määrittämiseksi ja ravintoväliaine Download PDF

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Publication number
FI112116B
FI112116B FI943745A FI943745A FI112116B FI 112116 B FI112116 B FI 112116B FI 943745 A FI943745 A FI 943745A FI 943745 A FI943745 A FI 943745A FI 112116 B FI112116 B FI 112116B
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protein
amino acids
nutrient medium
labeled
substituted
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FI943745A
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English (en)
Finnish (fi)
Swedish (sv)
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FI943745A (fi
FI943745A0 (fi
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Jonathan Miles Brown
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Martek Biosciences Corp
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/534—Production of labelled immunochemicals with radioactive label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI943745A 1993-02-05 1994-08-15 Menetelmä proteiinin 3-ulotteisen rakenneinformaation määrittämiseksi ja ravintoväliaine FI112116B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1424393 1993-02-05
US08/014,243 US5393669A (en) 1993-02-05 1993-02-05 Compositions and methods for protein structural determinations
PCT/US1994/001329 WO1994018339A1 (fr) 1993-02-05 1994-02-07 Compositions et procedes de determination de structures proteiniques
US9401329 1994-02-07

Publications (3)

Publication Number Publication Date
FI943745A FI943745A (fi) 1994-08-15
FI943745A0 FI943745A0 (fi) 1994-08-15
FI112116B true FI112116B (fi) 2003-10-31

Family

ID=21764312

Family Applications (1)

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FI943745A FI112116B (fi) 1993-02-05 1994-08-15 Menetelmä proteiinin 3-ulotteisen rakenneinformaation määrittämiseksi ja ravintoväliaine

Country Status (13)

Country Link
US (3) US5393669A (fr)
EP (3) EP1193271A3 (fr)
JP (4) JPH07506192A (fr)
AT (1) ATE221918T1 (fr)
AU (2) AU678446B2 (fr)
CA (1) CA2129904A1 (fr)
DE (1) DE69431142T2 (fr)
DK (1) DK0636183T3 (fr)
ES (1) ES2181715T3 (fr)
FI (1) FI112116B (fr)
NO (1) NO943703L (fr)
PT (1) PT636183E (fr)
WO (1) WO1994018339A1 (fr)

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US5393669A (en) * 1993-02-05 1995-02-28 Martek Biosciences Corp. Compositions and methods for protein structural determinations
DK0870197T4 (da) * 1995-11-14 2007-02-26 Abbott Lab Anvendelse af nuclear magnetisk resonans til design af ligander rettet mod biomolekyler
US5989827A (en) * 1995-11-14 1999-11-23 Abbott Laboratories Use of nuclear magnetic resonance to design ligands to target biomolecules
US5891643A (en) * 1995-11-14 1999-04-06 Abbott Laboratories Use of nuclear magnetic resonance to design ligands to target biomolecules
AU7731696A (en) * 1995-11-15 1997-06-05 Martek Corporation Photosynthetic production of stable isotopically labeled recombinant proteins
US6168912B1 (en) 1996-01-23 2001-01-02 Martek Biosciences Corporation Method and kit for making a multidimensional combinatorial chemical library
US6111066A (en) 1997-09-02 2000-08-29 Martek Biosciences Corporation Peptidic molecules which have been isotopically substituted with 13 C, 15 N and 2 H in the backbone but not in the sidechains
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
IL143927A0 (en) * 1998-12-30 2002-04-21 Nycomed Amersham Plc Nmr spectroscopic in vitro assay using hyperpolarization
WO2001001165A1 (fr) * 1999-06-25 2001-01-04 Battelle Memorial Institute Utilisation d'un solvant a pertes minimales pour augmenter la sensibilite des mesures par rmn haute resolution d'echantillons biologiques
CA2402871C (fr) 2000-05-05 2011-08-23 Purdue Research Foundation Identification etquantification de proteines par peptides de signature, isoles par selection d'affinite
US6762041B2 (en) 2000-05-15 2004-07-13 Ajinomoto Co., Inc. Method for isotope labeling of protein with enzyme
AU2002224440A1 (en) * 2000-10-20 2002-05-06 Martek Biosciences Corporation Rapid determination of protein global folds
US6882939B2 (en) * 2000-10-20 2005-04-19 Prospect Pharma Rapid determination of protein global folds
CA2441208A1 (fr) * 2001-03-12 2003-01-09 John D. Mendlein Proteines, zones de proteines pouvant etre ciblees et analyse de cibles servant a la composition chimique de medicaments
US7256047B2 (en) * 2001-05-01 2007-08-14 Board Of Regents, The University Of Texas System Measurement of gluconeogenesis and intermediary metabolism using stable isotopes
WO2003006488A1 (fr) * 2001-07-13 2003-01-23 The Regents Of The University Of California Spectroscopie rmn intracellulaire
CA2460819A1 (fr) * 2001-09-18 2003-03-27 Affinium Pharmaceuticals, Inc. Procedes et appareils de purification
AU2002341862C1 (en) * 2001-09-27 2009-01-29 Purdue Research Foundation Controlling isotope effects during fractionation of analytes
SI1436321T1 (sl) 2001-10-19 2006-12-31 Isotechnika Inc Sinteza analogov ciklosporina
EP1457482B9 (fr) * 2001-12-19 2012-10-24 Japan Science and Technology Agency Amino acide marqué par isotope stable, technique d'intégration de cet amino acide dans une protéine cible, technique d'analyse structurelle par IRM de protéine
US20050079526A1 (en) * 2002-02-20 2005-04-14 Affinium Pharmaceuticals, Inc. Methods and apparatuses for characterizing refolding and aggregation of biological molecules
WO2003071269A2 (fr) * 2002-02-20 2003-08-28 Affinium Pharmaceuticals, Inc. Methodes et dispositifs destines a caracteriser la stabilite de molecules biologiques
US20050181464A1 (en) * 2002-04-04 2005-08-18 Affinium Pharmaceuticals, Inc. Novel purified polypeptides from bacteria
WO2003087834A2 (fr) * 2002-04-08 2003-10-23 Affinium Pharmaceuticals, Inc. Purification, caracterisation et identification a haut rendement de proteines recombinantes
NO20023357D0 (no) * 2002-04-19 2002-07-11 Amersham Health As Blanding
AU2003245433A1 (en) * 2002-06-10 2003-12-22 Prospect Pharma Method for obtaining dynamic and structural data pertaining to proteins and protein/ligand complexes
US20040121445A1 (en) * 2002-07-31 2004-06-24 Fabien Marino Cell cultures
US20070184455A1 (en) * 2003-05-16 2007-08-09 Cheryl Arrowsmith Evaluation of spectra
US20070082399A1 (en) * 2003-07-11 2007-04-12 Tatiana A Egorova-Zachernyuk Compositions and method for stable isotope labelling of biological compounds
EP1678198A4 (fr) * 2003-10-07 2007-12-05 Prospect Pharma Aminoacides deuteres a chaine laterale et procedes d'utilisation associes
CA2544305C (fr) * 2003-10-31 2011-07-12 Japan Science And Technology Agency Acide amine aromatique marque avec un isotope stable, methode d'introduction de cet acide amine dans une proteine cible et methode d'analyse de la structure d'une proteine par irm
CN104745486B (zh) 2005-06-07 2018-01-16 帝斯曼营养品股份公司 生产脂质和抗氧化剂的真核微生物
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WO2008004088A2 (fr) * 2006-07-05 2008-01-10 Centre National De La Recherche Scientifique (C.N.R.S.) Procédé co-catalysé par fer-cuivre pour une liaison carbone-carbone ou carbone-hétéroatome
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CN104030942B (zh) * 2014-06-09 2016-08-24 浙江普洛医药科技有限公司 一种L-α-氨基丁酰胺盐酸盐的制备方法
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Also Published As

Publication number Publication date
US5393669A (en) 1995-02-28
US5627044A (en) 1997-05-06
DK0636183T3 (da) 2002-12-02
EP1193271A3 (fr) 2004-03-24
DE69431142D1 (de) 2002-09-12
EP1191033A2 (fr) 2002-03-27
NO943703L (no) 1994-11-23
EP0636183A1 (fr) 1995-02-01
AU711468B2 (en) 1999-10-14
EP1193271A2 (fr) 2002-04-03
EP0636183B1 (fr) 2002-08-07
ATE221918T1 (de) 2002-08-15
WO1994018339A1 (fr) 1994-08-18
EP0636183A4 (fr) 1997-01-22
PT636183E (pt) 2002-11-29
AU3608797A (en) 1997-12-04
JPH07506192A (ja) 1995-07-06
FI943745A (fi) 1994-08-15
ES2181715T3 (es) 2003-03-01
JP2004113248A (ja) 2004-04-15
JP2004125801A (ja) 2004-04-22
US5817474A (en) 1998-10-06
EP1191033A3 (fr) 2003-07-30
AU678446B2 (en) 1997-05-29
NO943703D0 (no) 1994-10-04
DE69431142T2 (de) 2003-10-09
AU6236394A (en) 1994-08-29
CA2129904A1 (fr) 1994-08-18
JP2004115528A (ja) 2004-04-15
FI943745A0 (fi) 1994-08-15

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