DK0636183T3 - Præparater og fremgangsmåder til proteinstrukturbestemmelse - Google Patents
Præparater og fremgangsmåder til proteinstrukturbestemmelseInfo
- Publication number
- DK0636183T3 DK0636183T3 DK94909555T DK94909555T DK0636183T3 DK 0636183 T3 DK0636183 T3 DK 0636183T3 DK 94909555 T DK94909555 T DK 94909555T DK 94909555 T DK94909555 T DK 94909555T DK 0636183 T3 DK0636183 T3 DK 0636183T3
- Authority
- DK
- Denmark
- Prior art keywords
- labeled
- protein
- amino acid
- acid mixture
- subjecting
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/12—Unicellular algae; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/014,243 US5393669A (en) | 1993-02-05 | 1993-02-05 | Compositions and methods for protein structural determinations |
PCT/US1994/001329 WO1994018339A1 (fr) | 1993-02-05 | 1994-02-07 | Compositions et procedes de determination de structures proteiniques |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0636183T3 true DK0636183T3 (da) | 2002-12-02 |
Family
ID=21764312
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94909555T DK0636183T3 (da) | 1993-02-05 | 1994-02-07 | Præparater og fremgangsmåder til proteinstrukturbestemmelse |
Country Status (13)
Country | Link |
---|---|
US (3) | US5393669A (fr) |
EP (3) | EP1191033A3 (fr) |
JP (4) | JPH07506192A (fr) |
AT (1) | ATE221918T1 (fr) |
AU (2) | AU678446B2 (fr) |
CA (1) | CA2129904A1 (fr) |
DE (1) | DE69431142T2 (fr) |
DK (1) | DK0636183T3 (fr) |
ES (1) | ES2181715T3 (fr) |
FI (1) | FI112116B (fr) |
NO (1) | NO943703L (fr) |
PT (1) | PT636183E (fr) |
WO (1) | WO1994018339A1 (fr) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5393669A (en) * | 1993-02-05 | 1995-02-28 | Martek Biosciences Corp. | Compositions and methods for protein structural determinations |
US5891643A (en) * | 1995-11-14 | 1999-04-06 | Abbott Laboratories | Use of nuclear magnetic resonance to design ligands to target biomolecules |
US5989827A (en) * | 1995-11-14 | 1999-11-23 | Abbott Laboratories | Use of nuclear magnetic resonance to design ligands to target biomolecules |
DE69613146T3 (de) * | 1995-11-14 | 2007-06-14 | Abbott Laboratories, Abbott Park | Verwendung von kernspinresonanz zur bestimmung von liganden für zielbiomoleküle |
WO1997018321A1 (fr) * | 1995-11-15 | 1997-05-22 | Martek Corporation | Production photosynthetique de proteines de recombinaison marqueespar des isotopes stables |
US6168912B1 (en) | 1996-01-23 | 2001-01-02 | Martek Biosciences Corporation | Method and kit for making a multidimensional combinatorial chemical library |
US6111066A (en) * | 1997-09-02 | 2000-08-29 | Martek Biosciences Corporation | Peptidic molecules which have been isotopically substituted with 13 C, 15 N and 2 H in the backbone but not in the sidechains |
US20030220234A1 (en) * | 1998-11-02 | 2003-11-27 | Selvaraj Naicker | Deuterated cyclosporine analogs and their use as immunodulating agents |
CA2356442C (fr) * | 1998-12-30 | 2009-03-24 | Nycomed Amersham Plc | Essai in vitro recourant a la spectroscopie rmn utilisant l'hyperpolarisation |
WO2001001165A1 (fr) * | 1999-06-25 | 2001-01-04 | Battelle Memorial Institute | Utilisation d'un solvant a pertes minimales pour augmenter la sensibilite des mesures par rmn haute resolution d'echantillons biologiques |
WO2001086306A2 (fr) * | 2000-05-05 | 2001-11-15 | Purdue Research Foundation | Peptides a signature a affinite selective permettant l'identification et la quantification de proteines |
US6762041B2 (en) * | 2000-05-15 | 2004-07-13 | Ajinomoto Co., Inc. | Method for isotope labeling of protein with enzyme |
WO2002035239A1 (fr) * | 2000-10-20 | 2002-05-02 | Martek Biosciences Corporation | Determination rapide de pliages de proteines globaux |
US6882939B2 (en) * | 2000-10-20 | 2005-04-19 | Prospect Pharma | Rapid determination of protein global folds |
WO2003002724A2 (fr) * | 2001-03-12 | 2003-01-09 | Affinium Pharmaceuticals, Inc. | Proteines, zones de proteines pouvant etre ciblees et analyse de cibles servant a la composition chimique de medicaments |
US7256047B2 (en) * | 2001-05-01 | 2007-08-14 | Board Of Regents, The University Of Texas System | Measurement of gluconeogenesis and intermediary metabolism using stable isotopes |
WO2003006488A1 (fr) * | 2001-07-13 | 2003-01-23 | The Regents Of The University Of California | Spectroscopie rmn intracellulaire |
WO2003025156A2 (fr) * | 2001-09-18 | 2003-03-27 | Affinium Pharmaceuticals, Inc. | Procedes et appareils de purification |
EP1432992A2 (fr) * | 2001-09-27 | 2004-06-30 | Purdue Research Foundation | Materiaux et procedes regulant les effets isotopiques lors du fractionnement d'analytes |
PL210795B1 (pl) | 2001-10-19 | 2012-03-30 | Isotechnika Inc | Sposób wytwarzania mieszaniny ISATX247 wzbogaconej w izomer (E), sposób wytwarzania mieszaniny ISATX247 wzbogaconej w izomer (Z), sposób stereoselektywnej syntezy izomeru (E) ISATX247, sposób stereoselektywnej syntezy izomeru (Z) ISATX247 i sposób wytwarzania mieszaniny izomerów ISATX247 |
WO2003053910A1 (fr) * | 2001-12-19 | 2003-07-03 | Japan Science And Technology Agency | Amino acide marque par isotope stable, technique d'integration de cet amino acide dans une proteine cible, technique d'analyse structurelle par irm de proteine et technique de production d'acide fumarique et d'acide tartrique marques par isotope stable a selection de site |
US20050079526A1 (en) * | 2002-02-20 | 2005-04-14 | Affinium Pharmaceuticals, Inc. | Methods and apparatuses for characterizing refolding and aggregation of biological molecules |
CA2477021A1 (fr) * | 2002-02-20 | 2003-08-28 | Affinium Pharmaceuticals, Inc. | Methodes et dispositifs destines a caracteriser la stabilite de molecules biologiques |
US20050181464A1 (en) * | 2002-04-04 | 2005-08-18 | Affinium Pharmaceuticals, Inc. | Novel purified polypeptides from bacteria |
WO2003087834A2 (fr) * | 2002-04-08 | 2003-10-23 | Affinium Pharmaceuticals, Inc. | Purification, caracterisation et identification a haut rendement de proteines recombinantes |
NO20023357D0 (no) * | 2002-04-19 | 2002-07-11 | Amersham Health As | Blanding |
CA2488773A1 (fr) * | 2002-06-10 | 2003-12-18 | Prospect Pharma | Procede pour obtenir des donnees dynamiques et structurelles sur des proteines et des complexes proteines/ligands |
US20040121445A1 (en) * | 2002-07-31 | 2004-06-24 | Fabien Marino | Cell cultures |
CA2466792A1 (fr) * | 2003-05-16 | 2004-11-16 | Affinium Pharmaceuticals, Inc. | Evaluation de spectres |
EP1644474B1 (fr) * | 2003-07-11 | 2012-06-27 | Tatiana A. Egorova-Zachernyuk | Compositions et procedes de marquage de composes biologiques avec des isotopes stables |
WO2005037853A2 (fr) * | 2003-10-07 | 2005-04-28 | Prospect Pharma | Aminoacides deuteres a chaine laterale et procedes d'utilisation associes |
CA2544305C (fr) | 2003-10-31 | 2011-07-12 | Japan Science And Technology Agency | Acide amine aromatique marque avec un isotope stable, methode d'introduction de cet acide amine dans une proteine cible et methode d'analyse de la structure d'une proteine par irm |
PL2447356T3 (pl) | 2005-06-07 | 2016-10-31 | Mikroorganizmy eukariotyczne do wytwarzania lipidów i przeciwutleniaczy | |
GB0604647D0 (en) | 2006-03-08 | 2006-04-19 | Shchepinov Mikhail | Stabilized food supplements and their derivatives |
WO2008004088A2 (fr) * | 2006-07-05 | 2008-01-10 | Centre National De La Recherche Scientifique (C.N.R.S.) | Procédé co-catalysé par fer-cuivre pour une liaison carbone-carbone ou carbone-hétéroatome |
ES2572833T3 (es) * | 2006-08-01 | 2016-06-02 | Dsm Nutritional Products Ag | Proceso de producción de aceite microbiano que contiene ácidos grasos poliinsaturados |
DE102011007790A1 (de) * | 2011-04-20 | 2012-10-25 | Wacker Chemie Ag | Verfahren zur Reinigung von L-Cystein |
WO2014141098A1 (fr) | 2013-03-13 | 2014-09-18 | Dsm Nutritional Products Ag | Modification génétique de micro-organismes |
US20140260586A1 (en) * | 2013-03-14 | 2014-09-18 | Schlumberger Technology Corporation | Method to perform rapid formation fluid analysis |
JP2015067581A (ja) * | 2013-09-30 | 2015-04-13 | 国立大学法人京都大学 | 多重共鳴用のプローブ |
EP3069127B1 (fr) * | 2013-11-13 | 2023-07-26 | NanoNord A/S | Procédé de détermination quantitative de l'azote dans un liquide aqueux |
CN104030942B (zh) * | 2014-06-09 | 2016-08-24 | 浙江普洛医药科技有限公司 | 一种L-α-氨基丁酰胺盐酸盐的制备方法 |
WO2017192460A1 (fr) * | 2016-05-02 | 2017-11-09 | Retrotope, Inc. | Composition isotopiquement modifiée et ses utilisations thérapeutiques |
CN107793209A (zh) * | 2016-08-30 | 2018-03-13 | 泰生科技香港有限公司 | 稳定性同位素标记植物的专用培养基、其制备方法及用途 |
JOP20190095A1 (ar) | 2016-10-27 | 2019-04-28 | Janssen Pharmaceutica Nv | مركبات ببتيد تيروسين-تيروسين الحلقية كمعدلات لمستقبلات الببتيد العصبي y |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4182656A (en) * | 1976-09-10 | 1980-01-08 | Johnston Laboratories, Inc. | Method for detecting the presence of biologically active agents utilizing 13 C-labeled substrates |
US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
JPS5811857A (ja) * | 1981-07-15 | 1983-01-22 | Yamasa Shoyu Co Ltd | アデノシンの定量法 |
DE69030765T2 (de) * | 1989-06-14 | 1997-12-18 | Martek Corp | Medien zur zellzucht und verfahren dazu |
JP2517688B2 (ja) * | 1989-12-25 | 1996-07-24 | 日本電子株式会社 | 3次元核磁気共鳴スペクトルの対称化処理方法 |
JPH0446143A (ja) * | 1990-06-11 | 1992-02-17 | Hitachi Ltd | 同位体多重標識アミノ酸の合成法 |
US5393669A (en) * | 1993-02-05 | 1995-02-28 | Martek Biosciences Corp. | Compositions and methods for protein structural determinations |
US5478729A (en) * | 1994-04-28 | 1995-12-26 | Syntex (U.S.A.) Inc. | Immunoassay for homocysteine |
-
1993
- 1993-02-05 US US08/014,243 patent/US5393669A/en not_active Expired - Fee Related
-
1994
- 1994-02-07 JP JP6518272A patent/JPH07506192A/ja active Pending
- 1994-02-07 DK DK94909555T patent/DK0636183T3/da active
- 1994-02-07 PT PT94909555T patent/PT636183E/pt unknown
- 1994-02-07 ES ES94909555T patent/ES2181715T3/es not_active Expired - Lifetime
- 1994-02-07 DE DE69431142T patent/DE69431142T2/de not_active Expired - Fee Related
- 1994-02-07 AU AU62363/94A patent/AU678446B2/en not_active Ceased
- 1994-02-07 EP EP01204506A patent/EP1191033A3/fr not_active Withdrawn
- 1994-02-07 EP EP94909555A patent/EP0636183B1/fr not_active Revoked
- 1994-02-07 EP EP01204505A patent/EP1193271A3/fr not_active Withdrawn
- 1994-02-07 AT AT94909555T patent/ATE221918T1/de not_active IP Right Cessation
- 1994-02-07 CA CA002129904A patent/CA2129904A1/fr not_active Abandoned
- 1994-02-07 WO PCT/US1994/001329 patent/WO1994018339A1/fr not_active Application Discontinuation
- 1994-02-07 US US08/307,768 patent/US5627044A/en not_active Expired - Fee Related
- 1994-08-15 FI FI943745A patent/FI112116B/fi not_active IP Right Cessation
- 1994-10-04 NO NO943703A patent/NO943703L/no not_active Application Discontinuation
-
1996
- 1996-07-16 US US08/680,637 patent/US5817474A/en not_active Expired - Fee Related
-
1997
- 1997-08-28 AU AU36087/97A patent/AU711468B2/en not_active Ceased
-
2003
- 2003-10-22 JP JP2003362292A patent/JP2004115528A/ja active Pending
- 2003-10-22 JP JP2003362290A patent/JP2004113248A/ja active Pending
- 2003-10-22 JP JP2003362288A patent/JP2004125801A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1193271A2 (fr) | 2002-04-03 |
NO943703D0 (no) | 1994-10-04 |
FI943745A0 (fi) | 1994-08-15 |
EP0636183B1 (fr) | 2002-08-07 |
DE69431142D1 (de) | 2002-09-12 |
FI943745A (fi) | 1994-08-15 |
ES2181715T3 (es) | 2003-03-01 |
AU3608797A (en) | 1997-12-04 |
EP0636183A1 (fr) | 1995-02-01 |
EP1193271A3 (fr) | 2004-03-24 |
NO943703L (no) | 1994-11-23 |
AU678446B2 (en) | 1997-05-29 |
JP2004115528A (ja) | 2004-04-15 |
FI112116B (fi) | 2003-10-31 |
DE69431142T2 (de) | 2003-10-09 |
JP2004125801A (ja) | 2004-04-22 |
US5627044A (en) | 1997-05-06 |
PT636183E (pt) | 2002-11-29 |
JPH07506192A (ja) | 1995-07-06 |
CA2129904A1 (fr) | 1994-08-18 |
AU711468B2 (en) | 1999-10-14 |
EP1191033A2 (fr) | 2002-03-27 |
EP0636183A4 (fr) | 1997-01-22 |
US5393669A (en) | 1995-02-28 |
US5817474A (en) | 1998-10-06 |
EP1191033A3 (fr) | 2003-07-30 |
JP2004113248A (ja) | 2004-04-15 |
WO1994018339A1 (fr) | 1994-08-18 |
AU6236394A (en) | 1994-08-29 |
ATE221918T1 (de) | 2002-08-15 |
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