DE3853224T2 - Produktion von Proteinen in aktiver Form. - Google Patents

Produktion von Proteinen in aktiver Form.

Info

Publication number
DE3853224T2
DE3853224T2 DE3853224T DE3853224T DE3853224T2 DE 3853224 T2 DE3853224 T2 DE 3853224T2 DE 3853224 T DE3853224 T DE 3853224T DE 3853224 T DE3853224 T DE 3853224T DE 3853224 T2 DE3853224 T2 DE 3853224T2
Authority
DE
Germany
Prior art keywords
protein
cationic exchange
proteins
active form
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3853224T
Other languages
English (en)
Other versions
DE3853224D1 (de
Inventor
Malcolm Roy Brandon
Joseph John Patroni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nantinco Nv Willensted Curacao An
Original Assignee
Southern Cross Biotech Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Cross Biotech Pty Ltd filed Critical Southern Cross Biotech Pty Ltd
Publication of DE3853224D1 publication Critical patent/DE3853224D1/de
Application granted granted Critical
Publication of DE3853224T2 publication Critical patent/DE3853224T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE3853224T 1987-04-21 1988-04-21 Produktion von Proteinen in aktiver Form. Expired - Fee Related DE3853224T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPI150887 1987-04-21

Publications (2)

Publication Number Publication Date
DE3853224D1 DE3853224D1 (de) 1995-04-13
DE3853224T2 true DE3853224T2 (de) 1995-06-29

Family

ID=3772123

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3853224T Expired - Fee Related DE3853224T2 (de) 1987-04-21 1988-04-21 Produktion von Proteinen in aktiver Form.

Country Status (11)

Country Link
US (1) US5008377A (de)
EP (1) EP0288280B1 (de)
JP (1) JPS646292A (de)
KR (1) KR880012753A (de)
AT (1) ATE119543T1 (de)
CA (1) CA1305285C (de)
DE (1) DE3853224T2 (de)
ES (1) ES2068827T3 (de)
MY (1) MY103362A (de)
NZ (1) NZ224295A (de)
ZA (1) ZA882774B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1305285C (en) * 1987-04-21 1992-07-14 Malcolm Roy Brandon Production of proteins in active forms
WO1992014832A1 (en) * 1991-02-26 1992-09-03 Ajinomoto Co., Inc. Processes for purifying human bcdf
US6031075A (en) * 1996-02-05 2000-02-29 Children's Hospital Medical Center Mature alveolar SP-B and a process for producing the same
US20030190307A1 (en) * 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
DE69943205D1 (de) 1998-08-06 2011-03-31 Mountain View Pharmaceuticals Peg-uricase Konjugate und Verwendung davon
CA2604399A1 (en) 2005-04-11 2006-10-19 Savient Pharmaceuticals, Inc. Variant forms of urate oxidase and use thereof
CZ2007700A3 (cs) 2005-04-11 2008-02-27 Savient Pharmaceuticals, Inc. Variantní forma urátoxidázy a její použití
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
US9534013B2 (en) * 2006-04-12 2017-01-03 Horizon Pharma Rheumatology Llc Purification of proteins with cationic surfactant
WO2006125452A1 (en) * 2005-05-23 2006-11-30 Universite De Geneve Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant
KR101861547B1 (ko) 2009-06-25 2018-07-02 크레알타 파마슈티칼스 엘엘씨 페길화된 유리카아제 치료 중에 혈청 요산을 모니터링하여 주입 반응의 위험성 및 반응의 항체­매개 상실을 예측하는 방법 및 키트

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2829089A1 (de) * 1977-07-13 1979-02-01 Sandoz Ag Subunit-vakzine
GB8508340D0 (en) * 1985-03-29 1985-05-09 Creighton T E Production of protein
US4748234A (en) * 1985-06-26 1988-05-31 Cetus Corporation Process for recovering refractile bodies containing heterologous proteins from microbial hosts
US4766224A (en) * 1985-08-19 1988-08-23 International Minerals & Chemical Corp. Purification and activation of proteins from insoluble inclusion bodies
US4677196A (en) * 1985-09-06 1987-06-30 International Minerals & Chemical Corp. Purification and activation of proteins from insoluble inclusion bodies
AU597924B2 (en) * 1985-12-11 1990-06-14 Natinco Nv Solubilization of protein aggregates
CA1305285C (en) * 1987-04-21 1992-07-14 Malcolm Roy Brandon Production of proteins in active forms

Also Published As

Publication number Publication date
EP0288280A2 (de) 1988-10-26
ES2068827T3 (es) 1995-05-01
EP0288280B1 (de) 1995-03-08
NZ224295A (en) 1990-06-26
ZA882774B (en) 1988-10-20
EP0288280A3 (en) 1990-04-11
CA1305285C (en) 1992-07-14
MY103362A (en) 1993-06-30
DE3853224D1 (de) 1995-04-13
KR880012753A (ko) 1988-11-29
JPS646292A (en) 1989-01-10
ATE119543T1 (de) 1995-03-15
US5008377A (en) 1991-04-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NANTINCO, NV, WILLENSTED, CURACAO, AN

8339 Ceased/non-payment of the annual fee