ATE70455T1 - Verfahren zur reinigung von serumalbumin. - Google Patents

Verfahren zur reinigung von serumalbumin.

Info

Publication number
ATE70455T1
ATE70455T1 AT88202578T AT88202578T ATE70455T1 AT E70455 T1 ATE70455 T1 AT E70455T1 AT 88202578 T AT88202578 T AT 88202578T AT 88202578 T AT88202578 T AT 88202578T AT E70455 T1 ATE70455 T1 AT E70455T1
Authority
AT
Austria
Prior art keywords
serum albumin
purification
procedure
followed
employing
Prior art date
Application number
AT88202578T
Other languages
English (en)
Inventor
Boudewijn Wynand Koenig
Michiel Nicolaas Hamers
Der Laken Cornelis Jacobus Van
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Application granted granted Critical
Publication of ATE70455T1 publication Critical patent/ATE70455T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT88202578T 1987-11-18 1988-11-17 Verfahren zur reinigung von serumalbumin. ATE70455T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP87202261 1987-11-18
EP88202578A EP0319067B1 (de) 1987-11-18 1988-11-17 Verfahren zur Reinigung von Serumalbumin

Publications (1)

Publication Number Publication Date
ATE70455T1 true ATE70455T1 (de) 1992-01-15

Family

ID=8197703

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88202578T ATE70455T1 (de) 1987-11-18 1988-11-17 Verfahren zur reinigung von serumalbumin.

Country Status (13)

Country Link
EP (1) EP0319067B1 (de)
JP (1) JP2562192B2 (de)
KR (1) KR970003053B1 (de)
AT (1) ATE70455T1 (de)
AU (1) AU620355B2 (de)
CA (1) CA1312031C (de)
DE (1) DE3867046D1 (de)
DK (1) DK639288A (de)
ES (1) ES2040834T3 (de)
FI (1) FI92404C (de)
GR (1) GR3003828T3 (de)
IE (1) IE61423B1 (de)
IL (1) IL88326A (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3230091B2 (ja) * 1990-06-25 2001-11-19 ウェルファイド株式会社 ヒト血清アルブミンの着色抑制方法
US5849874A (en) * 1991-07-12 1998-12-15 Gist-Brocades, N.V. Process for the purification of serum albumin
EP0933083A1 (de) 1991-07-12 1999-08-04 Dsm N.V. Verfahren zur Reinigung von Serumalbumin
FR2690444B1 (fr) * 1992-04-22 1995-07-13 Rucheton Marcel Procede de preparation d'une solution d'albumine plasmatique purifiee.
US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5440018A (en) * 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
ES2046122B1 (es) * 1992-06-04 1994-10-01 Grifols Grupo Sa Procedimiento para la obtencion de albumina serica humana purificada.
JP3360315B2 (ja) * 1992-07-31 2002-12-24 三菱ウェルファーマ株式会社 ヒト血清アルブミンの高度精製方法
US5728553A (en) 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
CA2116385A1 (en) * 1993-02-25 1994-08-26 Akinori Sumi Human serum albumin and process for producing the same
FR2746109B1 (fr) 1996-03-12 1998-04-17 Rhone Poulenc Rorer Sa Milieu pour la conservation de materiel biologique
DE19749277C2 (de) * 1997-11-07 2000-05-25 Univ Leipzig Peptid der Sequenz NH¶2¶-Phe-His-Glu-Asn-Trp-Pro-Ser-COOH und seine Verwendung
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
AU783571B2 (en) * 2000-10-24 2005-11-10 Km Biologics Co., Ltd. Method of monomerizing human serum albumin polymers
JP4798830B2 (ja) * 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の単量体化方法
JP4798832B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の除去方法
GB0217033D0 (en) 2002-07-23 2002-08-28 Delta Biotechnology Ltd Gene and polypeptide sequences
GB0329681D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Gene expression technique
GB0329722D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Modified plasmid and use thereof
EP2330200B1 (de) 2004-12-23 2017-04-05 Albumedix A/S Genexpressionstechnik
EP2594583A1 (de) 2007-08-08 2013-05-22 Novozymes Biopharma DK A/S Transferrinvarianten und Konjugate
CN102317315A (zh) 2009-02-11 2012-01-11 诺维信生物制药丹麦公司 白蛋白变体和缀合物
CA2776241A1 (en) 2009-10-30 2011-05-05 Novozymes Biopharma Dk A/S Albumin variants
KR20130070576A (ko) 2010-04-09 2013-06-27 노보자임스 바이오파마 디케이 에이/에스 알부민 유도체 및 변이체
EP2780364A2 (de) 2011-11-18 2014-09-24 Eleven Biotherapeutics, Inc. Proteine mit verbesserter halbwertzeit und anderen eigenschaften
PL2825556T3 (pl) 2012-03-16 2018-10-31 Albumedix A/S Warianty albuminy
JP6487328B2 (ja) 2012-11-08 2019-03-20 アルブミディクス リミティド アルブミン変異体
US10627415B2 (en) 2015-03-12 2020-04-21 Board Of Trustees Of Michigan State University Compositions and methods for diagnosing, monitoring, and treating an autoimmune disease
US10633428B2 (en) 2015-08-20 2020-04-28 Albumedix Ltd Albumin variants and conjugates
CN108431204A (zh) 2015-12-22 2018-08-21 阿尔布梅迪克斯医疗有限公司 改良的表达蛋白质的菌株
JP7282693B2 (ja) 2017-06-20 2023-05-29 アルブミディクス リミティド 改良されたタンパク質発現株
CN111871396A (zh) * 2020-08-03 2020-11-03 中国科学院过程工程研究所 一种白蛋白静电亲和双模式层析介质及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1471006A (en) * 1973-07-11 1977-04-21 New Zealand Inventions Dev Preparation of albumin
SE405549B (sv) * 1975-10-09 1978-12-18 Pharmacia Fine Chemicals Ab Forfarande for isolering av albumin ur plasmaprodukter genom kromatografisk fraktionering
US4228154A (en) * 1979-02-26 1980-10-14 Armour Pharmaceutical Company Purification of plasma albumin by ion exchange chromatography
IL66614A (en) * 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it

Also Published As

Publication number Publication date
JP2562192B2 (ja) 1996-12-11
IE883435L (en) 1989-05-18
CA1312031C (en) 1992-12-29
KR970003053B1 (ko) 1997-03-14
IL88326A (en) 1993-03-15
JPH0231687A (ja) 1990-02-01
DK639288A (da) 1989-05-19
GR3003828T3 (de) 1993-03-16
AU620355B2 (en) 1992-02-20
EP0319067B1 (de) 1991-12-18
IL88326A0 (en) 1989-06-30
DK639288D0 (da) 1988-11-16
AU2572688A (en) 1989-05-18
FI885341A0 (fi) 1988-11-17
KR890007753A (ko) 1989-07-05
FI92404B (fi) 1994-07-29
ES2040834T3 (es) 1993-11-01
FI885341A (fi) 1989-05-19
DE3867046D1 (de) 1992-01-30
FI92404C (fi) 1994-11-10
EP0319067A1 (de) 1989-06-07
IE61423B1 (en) 1994-11-02

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee