FI110779B - Menetelmä indolijohdannaisten valmistamiseksi, jotka sisältävät 1,2,4- triatsol-1-yylisubstituentin - Google Patents

Menetelmä indolijohdannaisten valmistamiseksi, jotka sisältävät 1,2,4- triatsol-1-yylisubstituentin Download PDF

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Publication number
FI110779B
FI110779B FI950193A FI950193A FI110779B FI 110779 B FI110779 B FI 110779B FI 950193 A FI950193 A FI 950193A FI 950193 A FI950193 A FI 950193A FI 110779 B FI110779 B FI 110779B
Authority
FI
Finland
Prior art keywords
formula
compound
defined above
derivative
reaction
Prior art date
Application number
FI950193A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI950193A0 (fi
FI950193A (fi
Inventor
Peter Grenville Houghton
Original Assignee
Merck Sharp & Dohme
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Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of FI950193A0 publication Critical patent/FI950193A0/fi
Publication of FI950193A publication Critical patent/FI950193A/fi
Application granted granted Critical
Publication of FI110779B publication Critical patent/FI110779B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI950193A 1992-07-22 1995-01-17 Menetelmä indolijohdannaisten valmistamiseksi, jotka sisältävät 1,2,4- triatsol-1-yylisubstituentin FI110779B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9215526 1992-07-22
GB929215526A GB9215526D0 (en) 1992-07-22 1992-07-22 Chemical process
PCT/GB1993/001493 WO1994002476A1 (en) 1992-07-22 1993-07-15 Process for preparing indole derivatives containing a 1,2,4-triazol-1-yl substituent
GB9301493 1993-07-15

Publications (3)

Publication Number Publication Date
FI950193A0 FI950193A0 (fi) 1995-01-17
FI950193A FI950193A (fi) 1995-01-17
FI110779B true FI110779B (fi) 2003-03-31

Family

ID=10719083

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950193A FI110779B (fi) 1992-07-22 1995-01-17 Menetelmä indolijohdannaisten valmistamiseksi, jotka sisältävät 1,2,4- triatsol-1-yylisubstituentin

Country Status (23)

Country Link
US (2) US5567819A (ru)
EP (1) EP0651748B1 (ru)
JP (1) JP3472300B2 (ru)
KR (1) KR100286846B1 (ru)
CN (2) CN1037843C (ru)
AT (1) ATE159017T1 (ru)
AU (1) AU672215B2 (ru)
CA (1) CA2140146C (ru)
CZ (1) CZ281986B6 (ru)
DE (1) DE69314492T2 (ru)
DK (1) DK0651748T3 (ru)
ES (1) ES2107675T3 (ru)
FI (1) FI110779B (ru)
GB (1) GB9215526D0 (ru)
GR (1) GR3024957T3 (ru)
HU (1) HUT71901A (ru)
MX (1) MX9304419A (ru)
NZ (1) NZ254199A (ru)
RO (1) RO113348B1 (ru)
RU (1) RU2126003C1 (ru)
SK (1) SK279468B6 (ru)
UA (1) UA43322C2 (ru)
WO (1) WO1994002476A1 (ru)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2138649A1 (en) * 1992-07-24 1994-02-03 Raymond Baker Imidazole, triazole and tetrazole derivatives
US5567824A (en) * 1994-05-24 1996-10-22 Merck & Co., Inc. Palladium catalyzed ring closure of triazolyltryptamine
WO1996000223A1 (en) * 1994-06-24 1996-01-04 Takeda Chemical Industries, Ltd. Processes for production of quinoline or quinazoline derivatives and intermediates therefor
US5877329A (en) * 1996-08-13 1999-03-02 Merck & Co., Inc. Palladium catalyzed indolization
US5808064A (en) * 1996-08-13 1998-09-15 Merck & Co., Inc. Palladium catalyzed indolization
US5811551A (en) * 1996-08-13 1998-09-22 Merck & Co., Inc. Palladium catalyzed indolization
WO2002079153A1 (en) * 2001-03-28 2002-10-10 Biocatalytics, Inc. Method for producing tryptamine derivatives
WO2004000835A1 (de) 2002-06-24 2003-12-31 Basf Aktiengesellschaft Verfahren zur herstellung von 1,2,4-triazolylmethyl-oxiranen
ES2204303B2 (es) * 2002-08-07 2004-12-16 Laboratorios Vita, S.A. Procedimiento para la obtencion de un compuesto farmaceuticamente activo.
CA2515181C (en) 2003-02-06 2011-02-01 Sun Pharmaceutical Industries Limited Regiospecific process for the preparation of 4-[1-(4-cyanophenyl)-1-(1,2,4-triazol-1-yl)methyl]benzonitrile
US20090062550A1 (en) * 2005-11-14 2009-03-05 Matrix Laboratories Ltd Process for the Large Scale Production of Rizatriptan Benzoate
WO2007083320A2 (en) 2006-01-19 2007-07-26 Matrix Laboratories Ltd Conversion of aromatic diazonium salt to aryl hydrazine
CN104402871A (zh) * 2014-12-01 2015-03-11 江苏耕耘化学有限公司 专一制备2-(1h-1,2,4-三唑-1-基甲基)-1,3-二噁戊烷衍生物的方法
JP7126260B2 (ja) 2016-01-27 2022-08-26 インスター テクノロジーズ アクチオヴァ スプルチュノスト 治療処置用の口腔粘膜ナノファイバ担体
CN110028458B (zh) * 2019-05-09 2022-10-11 广东广康生化科技股份有限公司 一种制备叶菌唑的新方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2945549A1 (de) * 1979-11-10 1981-05-21 Röhm GmbH, 6100 Darmstadt Fluesiges, durch uv-strahlung haertbares ueberzugs- und bindemittel
GB8724912D0 (en) * 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi

Also Published As

Publication number Publication date
UA43322C2 (uk) 2001-12-17
SK6595A3 (en) 1995-07-11
SK279468B6 (sk) 1998-11-04
GB9215526D0 (en) 1992-09-02
CA2140146C (en) 2004-09-07
EP0651748B1 (en) 1997-10-08
CN1166486A (zh) 1997-12-03
DE69314492D1 (de) 1997-11-13
DE69314492T2 (de) 1998-04-16
ATE159017T1 (de) 1997-10-15
GR3024957T3 (en) 1998-01-30
AU4578393A (en) 1994-02-14
WO1994002476A1 (en) 1994-02-03
DK0651748T3 (da) 1997-10-27
CN1037843C (zh) 1998-03-25
EP0651748A1 (en) 1995-05-10
MX9304419A (es) 1994-03-31
CN1053660C (zh) 2000-06-21
AU672215B2 (en) 1996-09-26
ES2107675T3 (es) 1997-12-01
CZ9195A3 (en) 1995-09-13
US5567819A (en) 1996-10-22
FI950193A0 (fi) 1995-01-17
CN1085555A (zh) 1994-04-20
RU2126003C1 (ru) 1999-02-10
HUT71901A (en) 1996-02-28
JP3472300B2 (ja) 2003-12-02
RU95104979A (ru) 1996-10-27
RO113348B1 (ro) 1998-06-30
HU9500183D0 (en) 1995-03-28
CA2140146A1 (en) 1994-02-03
CZ281986B6 (cs) 1997-04-16
JPH07509697A (ja) 1995-10-26
KR100286846B1 (ko) 2001-04-16
US5717104A (en) 1998-02-10
FI950193A (fi) 1995-01-17
NZ254199A (en) 1996-04-26

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