DK0651748T3 - Fremgangsmåde til fremstilling af af indolderivater indeholdende en 1,2,4-triazol-1-yl-substituent - Google Patents

Fremgangsmåde til fremstilling af af indolderivater indeholdende en 1,2,4-triazol-1-yl-substituent

Info

Publication number
DK0651748T3
DK0651748T3 DK93916086.7T DK93916086T DK0651748T3 DK 0651748 T3 DK0651748 T3 DK 0651748T3 DK 93916086 T DK93916086 T DK 93916086T DK 0651748 T3 DK0651748 T3 DK 0651748T3
Authority
DK
Denmark
Prior art keywords
triazolyl
triazol
derivative
substituent
preparation
Prior art date
Application number
DK93916086.7T
Other languages
English (en)
Inventor
Peter Grenville Houghton
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of DK0651748T3 publication Critical patent/DK0651748T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK93916086.7T 1992-07-22 1993-07-15 Fremgangsmåde til fremstilling af af indolderivater indeholdende en 1,2,4-triazol-1-yl-substituent DK0651748T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929215526A GB9215526D0 (en) 1992-07-22 1992-07-22 Chemical process

Publications (1)

Publication Number Publication Date
DK0651748T3 true DK0651748T3 (da) 1997-10-27

Family

ID=10719083

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93916086.7T DK0651748T3 (da) 1992-07-22 1993-07-15 Fremgangsmåde til fremstilling af af indolderivater indeholdende en 1,2,4-triazol-1-yl-substituent

Country Status (23)

Country Link
US (2) US5567819A (da)
EP (1) EP0651748B1 (da)
JP (1) JP3472300B2 (da)
KR (1) KR100286846B1 (da)
CN (2) CN1037843C (da)
AT (1) ATE159017T1 (da)
AU (1) AU672215B2 (da)
CA (1) CA2140146C (da)
CZ (1) CZ281986B6 (da)
DE (1) DE69314492T2 (da)
DK (1) DK0651748T3 (da)
ES (1) ES2107675T3 (da)
FI (1) FI110779B (da)
GB (1) GB9215526D0 (da)
GR (1) GR3024957T3 (da)
HU (1) HUT71901A (da)
MX (1) MX9304419A (da)
NZ (1) NZ254199A (da)
RO (1) RO113348B1 (da)
RU (1) RU2126003C1 (da)
SK (1) SK279468B6 (da)
UA (1) UA43322C2 (da)
WO (1) WO1994002476A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU672802B2 (en) * 1992-07-24 1996-10-17 Merck Sharp & Dohme Limited Imidazole, triazole and tetrazole derivatives
US5567824A (en) * 1994-05-24 1996-10-22 Merck & Co., Inc. Palladium catalyzed ring closure of triazolyltryptamine
CA2193110C (en) * 1994-06-24 2001-09-04 Takeda Chemical Industries, Ltd. Processes for production of quinoline or quinazoline derivatives and intermediates therefor
US5811551A (en) * 1996-08-13 1998-09-22 Merck & Co., Inc. Palladium catalyzed indolization
US5877329A (en) * 1996-08-13 1999-03-02 Merck & Co., Inc. Palladium catalyzed indolization
US5808064A (en) * 1996-08-13 1998-09-15 Merck & Co., Inc. Palladium catalyzed indolization
US20030096379A1 (en) * 2001-03-28 2003-05-22 Kilgore James L. Method for producing tryptamine derivatives
BR0311461A (pt) * 2002-06-24 2005-03-29 Basf Ag Processo para a preparação de 1,2,4-triazol-1-ilmetiloxiranos, e, composto
ES2204303B2 (es) 2002-08-07 2004-12-16 Laboratorios Vita, S.A. Procedimiento para la obtencion de un compuesto farmaceuticamente activo.
EP1594850A2 (en) 2003-02-06 2005-11-16 Sun Pharmaceuticals Industries Ltd. Regiospecific process for the preparation of 4- 1- (4-cyanophenyl)-1-(1,2,4-triazol-1-yl)methyl]benzonitrile
WO2007054979A1 (en) * 2005-11-14 2007-05-18 Matrix Laboratories Ltd Process for the large scale production of rizatriptan benzoate
EP1981860B1 (en) 2006-01-19 2011-05-25 Matrix Laboratories Ltd Conversion of aromatic diazonium salt to aryl hydrazine
CN104402871A (zh) * 2014-12-01 2015-03-11 江苏耕耘化学有限公司 专一制备2-(1h-1,2,4-三唑-1-基甲基)-1,3-二噁戊烷衍生物的方法
AU2017211684B2 (en) 2016-01-27 2022-10-06 Instar Technologies A.S. Oromucosal nanofiber carriers for therapeutic treatment
CN110028458B (zh) * 2019-05-09 2022-10-11 广东广康生化科技股份有限公司 一种制备叶菌唑的新方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2945549A1 (de) * 1979-11-10 1981-05-21 Röhm GmbH, 6100 Darmstadt Fluesiges, durch uv-strahlung haertbares ueberzugs- und bindemittel
GB8724912D0 (en) * 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
SK278998B6 (sk) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i

Also Published As

Publication number Publication date
AU4578393A (en) 1994-02-14
SK6595A3 (en) 1995-07-11
JPH07509697A (ja) 1995-10-26
GR3024957T3 (en) 1998-01-30
NZ254199A (en) 1996-04-26
DE69314492T2 (de) 1998-04-16
KR100286846B1 (ko) 2001-04-16
EP0651748A1 (en) 1995-05-10
HUT71901A (en) 1996-02-28
CN1166486A (zh) 1997-12-03
CN1053660C (zh) 2000-06-21
CA2140146A1 (en) 1994-02-03
CN1037843C (zh) 1998-03-25
US5567819A (en) 1996-10-22
UA43322C2 (uk) 2001-12-17
MX9304419A (es) 1994-03-31
RO113348B1 (ro) 1998-06-30
CZ281986B6 (cs) 1997-04-16
WO1994002476A1 (en) 1994-02-03
ES2107675T3 (es) 1997-12-01
FI110779B (fi) 2003-03-31
US5717104A (en) 1998-02-10
EP0651748B1 (en) 1997-10-08
CZ9195A3 (en) 1995-09-13
HU9500183D0 (en) 1995-03-28
SK279468B6 (sk) 1998-11-04
DE69314492D1 (de) 1997-11-13
ATE159017T1 (de) 1997-10-15
RU2126003C1 (ru) 1999-02-10
AU672215B2 (en) 1996-09-26
FI950193A0 (fi) 1995-01-17
JP3472300B2 (ja) 2003-12-02
FI950193A (fi) 1995-01-17
CA2140146C (en) 2004-09-07
CN1085555A (zh) 1994-04-20
GB9215526D0 (en) 1992-09-02
RU95104979A (ru) 1996-10-27

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