FI110546B - Anti-HCV-vasta-aineiden immunomääritykset käyttäen antigeenejä joissa on konformaatioepitooppeja - Google Patents

Anti-HCV-vasta-aineiden immunomääritykset käyttäen antigeenejä joissa on konformaatioepitooppeja Download PDF

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Publication number
FI110546B
FI110546B FI950002A FI950002A FI110546B FI 110546 B FI110546 B FI 110546B FI 950002 A FI950002 A FI 950002A FI 950002 A FI950002 A FI 950002A FI 110546 B FI110546 B FI 110546B
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FI
Finland
Prior art keywords
hcv
antigens
antigen
antibodies
cells
Prior art date
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FI950002A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI950002A0 (fi
FI950002A (fi
Inventor
David Y Chien
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Chiron Corp
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Application filed by Chiron Corp filed Critical Chiron Corp
Publication of FI950002A0 publication Critical patent/FI950002A0/fi
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Application granted granted Critical
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
FI950002A 1992-07-07 1995-01-02 Anti-HCV-vasta-aineiden immunomääritykset käyttäen antigeenejä joissa on konformaatioepitooppeja FI110546B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US91075992A 1992-07-07 1992-07-07
US91075992 1992-07-07
PCT/US1993/006309 WO1994001778A1 (fr) 1992-07-07 1993-07-02 Dosages immunologiques pour anticorps diriges contre le virus de l'hepatite c (hcv) a l'aide d'antigenes comprenant des epitopes a conformation
US9306309 1993-07-02

Publications (3)

Publication Number Publication Date
FI950002A0 FI950002A0 (fi) 1995-01-02
FI950002A FI950002A (fi) 1995-02-27
FI110546B true FI110546B (fi) 2003-02-14

Family

ID=25429280

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950002A FI110546B (fi) 1992-07-07 1995-01-02 Anti-HCV-vasta-aineiden immunomääritykset käyttäen antigeenejä joissa on konformaatioepitooppeja

Country Status (19)

Country Link
US (1) US20020150883A1 (fr)
EP (1) EP0649537B2 (fr)
JP (2) JP3490085B2 (fr)
AT (1) ATE216779T1 (fr)
AU (1) AU685059B2 (fr)
CA (1) CA2139645C (fr)
CZ (1) CZ291951B6 (fr)
DE (1) DE69331845T3 (fr)
DK (1) DK0649537T4 (fr)
ES (1) ES2171414T5 (fr)
FI (1) FI110546B (fr)
HU (1) HUT70473A (fr)
NO (1) NO321185B1 (fr)
PL (1) PL174686B1 (fr)
PT (1) PT649537E (fr)
RU (1) RU2126158C1 (fr)
SK (1) SK284556B6 (fr)
UA (1) UA39944C2 (fr)
WO (1) WO1994001778A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274148B1 (en) * 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
DK0721505T4 (da) 1994-07-29 2006-08-14 Innogenetics Nv Rensede hepatitis C-virus-kappeproteiner til diagnostisk og terapeutisk anvendelse
DE4428705A1 (de) * 1994-08-12 1996-02-15 Boehringer Mannheim Gmbh Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus
US5707385A (en) * 1994-11-16 1998-01-13 Advanced Cardiovascular Systems, Inc. Drug loaded elastic membrane and method for delivery
WO1996041196A1 (fr) * 1995-06-07 1996-12-19 Abbott Laboratories Procede de detection d'un anticorps contre la deuxieme glycoproteine d'enveloppe du virus de l'hepatite c
US6514731B1 (en) 1996-05-24 2003-02-04 Chiron Corporation Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
WO2000026673A1 (fr) * 1998-11-03 2000-05-11 Abbott Laboratories Methodes de detection d'une infection chronique provoquee par le virus de l'hepatite c (vhc)
US6815160B1 (en) 1999-07-28 2004-11-09 Chiron Corporation Hepatitis C viral antigen immunoassay detection systems
ATE352785T1 (de) * 1999-07-28 2007-02-15 Novartis Vaccines & Diagnostic Verfahren zum nachweis von hepatitis c antigenen
BRPI0111731C1 (pt) 2000-06-15 2021-07-27 Chiron Corp suporte sólido de imunoensaio, métodos de detecção de infecção pelo vírus da hepatite c (hcv) em uma amostra biológica, e de produção de um suporte sólido de imunoensaio, e, kit de teste de imunodiagnóstico
EP1829891B1 (fr) 2000-06-15 2012-12-26 Novartis Vaccines and Diagnostics, Inc. Immunoessais pour anticorps anti-VHC
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
CA2498228C (fr) 2002-09-09 2011-03-22 Chiron Corporation Dosage biologique dans le cas du virus de l'hepatite c
WO2004071414A2 (fr) * 2003-02-05 2004-08-26 Genzyme Corporation Composes therapeutiques anti-vhc (al9)
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
EP1799868B1 (fr) * 2004-08-27 2012-01-18 Novartis Vaccines and Diagnostics, Inc. Mutants de proteines non structurelles du vhc et leurs utilisations
CA2661492A1 (fr) 2006-08-25 2008-02-28 Novartis Ag Polypeptides de fusion du vhc
US8815253B2 (en) 2007-12-07 2014-08-26 Novartis Ag Compositions for inducing immune responses
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
CA2906407A1 (fr) 2013-03-14 2014-09-18 Abbott Laboratories Antigenes recombinants ns3 de vhc et leurs mutants pour la detection d'anticorps amelioree
JP6739329B2 (ja) 2013-03-14 2020-08-12 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ Ｈｃｖコア脂質結合ドメインモノクローナル抗体
MX362075B (es) 2013-03-14 2019-01-07 Abbott Lab Ensayo de combinación de antígeno-anticuerpo del virus de la hepatitis c (vhc) y métodos y composiciones para usarlo.
JP6859314B2 (ja) 2015-03-27 2021-04-14 オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッドＯｒｔｈｏ−Ｃｌｉｎｉｃａｌ Ｄｉａｇｎｏｓｔｉｃｓ， Ｉｎｃ． Ｈｃｖ ｎｓ４ａ／改変されたｎｓ３ポリペプチド及びその使用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855224A (en) * 1984-03-09 1989-08-08 Genentech, Inc. Molecularly cloned diagnostic product and method of use
CN1049686C (zh) 1987-11-18 2000-02-23 希龙股份有限公司 非ａ和非ｂ肝炎病毒的诊断及疫苗
KR0185373B1 (ko) 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
US5372928A (en) * 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
DK298190A (da) * 1989-12-18 1991-06-19 Wellcome Found Viralt middel
ZA912040B (en) * 1990-03-30 1991-12-24 Akzo Nv Peptides immunochemically reactive with antibodies directed against hepatitis non-a,non-b virus
UA41266C2 (uk) * 1990-04-04 2001-09-17 Чірон Корпорейшн Комбінація послідовностей епітопів вірусу гепатиту с (hcv), спосіб виявлення антитіл до вірусу гепатиту с (hcv), набір для виконання аналізу при виявленні антитіл до антигену гепатиту с (hcv)
US5443965A (en) * 1990-04-06 1995-08-22 Genelabs Incorporated Hepatitis C virus epitopes
CA2045326A1 (fr) * 1990-06-25 1991-12-26 Hiroto Okayama Particules du virus de l'hepatite non-a, non-b
EP0468657A3 (en) * 1990-07-09 1992-02-05 Tonen Corporation Non-a non b hepatitis-specific antigen and its use in hepatitus diagnosis
JPH06504431A (ja) * 1990-11-08 1994-05-26 カイロン　コーポレイション Ｃ型肝炎ウイルスアシアロ糖タンパク質
IT1249684B (it) * 1991-07-19 1995-03-09 Sorin Biomedica Spa Epitopi della proteina env del virus dell'epatite c.
DE69333269T2 (de) * 1992-01-31 2004-07-29 Abbott Laboratories, Abbott Park Expressionssystem in säugetieren für hcv-proteine
US5587285A (en) * 1992-01-31 1996-12-24 University Of Texas System Generation serological assay for monitoring HIV exposure

Also Published As

Publication number Publication date
DE69331845D1 (de) 2002-06-06
NO321185B1 (no) 2006-04-03
EP0649537B2 (fr) 2006-02-22
NO950006L (no) 1995-02-24
UA39944C2 (uk) 2001-07-16
AU4662993A (en) 1994-01-31
RU2126158C1 (ru) 1999-02-10
EP0649537B1 (fr) 2002-04-24
ES2171414T3 (es) 2002-09-16
JP2003329687A (ja) 2003-11-19
CZ695A3 (en) 1996-03-13
JPH07509060A (ja) 1995-10-05
WO1994001778A1 (fr) 1994-01-20
FI950002A0 (fi) 1995-01-02
CZ291951B6 (cs) 2003-06-18
DE69331845T2 (de) 2002-08-14
PL307178A1 (en) 1995-05-02
HUT70473A (en) 1995-10-30
FI950002A (fi) 1995-02-27
AU685059B2 (en) 1998-01-15
DK0649537T4 (da) 2006-04-10
DE69331845T3 (de) 2006-10-05
DK0649537T3 (da) 2002-06-17
US20020150883A1 (en) 2002-10-17
ES2171414T5 (es) 2006-09-01
EP0649537A1 (fr) 1995-04-26
HU9500008D0 (en) 1995-03-28
CA2139645A1 (fr) 1994-01-20
PL174686B1 (pl) 1998-08-31
NO950006D0 (no) 1995-01-02
SK495A3 (en) 1995-07-11
RU94046284A (ru) 1997-02-27
JP3490085B2 (ja) 2004-01-26
ATE216779T1 (de) 2002-05-15
PT649537E (pt) 2002-09-30
SK284556B6 (sk) 2005-06-02
CA2139645C (fr) 2003-02-11

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