FI106844B - Menetelmä Moraxella catarrhalisin antigeeneihin liittyvien koostumusten ja vasta-aineiden valmistamiseksi sekä DNA-segmentti, yhdistelmävektori ja yhdistelmäisäntäsolu - Google Patents
Menetelmä Moraxella catarrhalisin antigeeneihin liittyvien koostumusten ja vasta-aineiden valmistamiseksi sekä DNA-segmentti, yhdistelmävektori ja yhdistelmäisäntäsolu Download PDFInfo
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- FI106844B FI106844B FI940681A FI940681A FI106844B FI 106844 B FI106844 B FI 106844B FI 940681 A FI940681 A FI 940681A FI 940681 A FI940681 A FI 940681A FI 106844 B FI106844 B FI 106844B
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- 102000020233 phosphotransferase Human genes 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 238000002264 polyacrylamide gel electrophoresis Methods 0.000 description 1
- 230000008488 polyadenylation Effects 0.000 description 1
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- 229920001282 polysaccharide Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 235000011118 potassium hydroxide Nutrition 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
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- 238000011896 sensitive detection Methods 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 201000009890 sinusitis Diseases 0.000 description 1
- 238000002741 site-directed mutagenesis Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000011895 specific detection Methods 0.000 description 1
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- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 238000000856 sucrose gradient centrifugation Methods 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 229940072172 tetracycline antibiotic Drugs 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- TXEYQDLBPFQVAA-UHFFFAOYSA-N tetrafluoromethane Chemical compound FC(F)(F)F TXEYQDLBPFQVAA-UHFFFAOYSA-N 0.000 description 1
- PSWFFKRAVBDQEG-YGQNSOCVSA-N thymopentin Chemical compound NC(N)=NCCC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 PSWFFKRAVBDQEG-YGQNSOCVSA-N 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
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- 150000003626 triacylglycerols Chemical class 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000002525 ultrasonication Methods 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 229940125575 vaccine candidate Drugs 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
- C07K14/212—Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/745,591 US5552146A (en) | 1991-08-15 | 1991-08-15 | Methods and compositions relating to useful antigens of Moraxella catarrhalis |
| US74559191 | 1991-08-15 | ||
| PCT/US1992/006869 WO1993003761A1 (en) | 1991-08-15 | 1992-08-14 | METHODS AND COMPOSITIONS RELATING TO USEFUL ANTIGENS OF $i(MORAXELLA CATARRHALIS) |
| US9206869 | 1992-08-14 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI940681A0 FI940681A0 (fi) | 1994-02-14 |
| FI940681A FI940681A (fi) | 1994-04-07 |
| FI106844B true FI106844B (fi) | 2001-04-30 |
Family
ID=24997358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI940681A FI106844B (fi) | 1991-08-15 | 1994-02-14 | Menetelmä Moraxella catarrhalisin antigeeneihin liittyvien koostumusten ja vasta-aineiden valmistamiseksi sekä DNA-segmentti, yhdistelmävektori ja yhdistelmäisäntäsolu |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US5552146A (no) |
| EP (1) | EP0612250B1 (no) |
| JP (1) | JP3499868B2 (no) |
| KR (1) | KR100271888B1 (no) |
| AT (1) | ATE140627T1 (no) |
| AU (1) | AU666329B2 (no) |
| CA (1) | CA2115565C (no) |
| DE (1) | DE69212495T2 (no) |
| DK (1) | DK0612250T3 (no) |
| ES (1) | ES2092696T3 (no) |
| FI (1) | FI106844B (no) |
| GR (1) | GR3021423T3 (no) |
| NO (2) | NO308413B1 (no) |
| WO (1) | WO1993003761A1 (no) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2693654B1 (fr) * | 1992-07-20 | 1994-08-26 | Oreal | Médicament, notamment immunomodulateur, contenant des enveloppes ou fractions d'enveloppes de bactéries filamenteuses non photosynthétiques et non fructifiantes, et sa préparation. |
| DE69423383T2 (de) * | 1993-05-13 | 2000-08-24 | American Cyanamid Co | Herstellung und Verwendungen von LOS-verminderten Aussenmembran-Proteinen von Gram-negativen Kokken |
| US5712118A (en) * | 1993-09-29 | 1998-01-27 | Research Foundation Of State University Of New York | Vaccine for branhamella catarrhalis |
| US5607846A (en) * | 1994-05-17 | 1997-03-04 | Research Foundation Of State University Of New York | Vaccine for moraxella catarrhalis |
| US6121427A (en) * | 1994-10-24 | 2000-09-19 | Connaught Laboratories Limited | Major outer membrane protein CD of branhamella |
| US6440425B1 (en) * | 1995-05-01 | 2002-08-27 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
| US6335018B1 (en) * | 1995-05-01 | 2002-01-01 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
| US6290970B1 (en) * | 1995-10-11 | 2001-09-18 | Aventis Pasteur Limited | Transferrin receptor protein of Moraxella |
| US7341727B1 (en) * | 1996-05-03 | 2008-03-11 | Emergent Product Development Gaithersburg Inc. | M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same |
| KR100500000B1 (ko) * | 1996-05-03 | 2005-12-12 | 안텍스 바이오로직스 인코퍼레이션 | 모락셀라카타르할리스외측막단백질-16폴리펩티드,이의유전자서열및이의용도 |
| US6004562A (en) * | 1996-08-16 | 1999-12-21 | The Research Foundation Of The State University Of New York | Outer membrane protein B1 of Moraxella catarrhalis |
| US6558677B2 (en) * | 1996-10-15 | 2003-05-06 | Wendell D. Zollinger | Vaccine against gram negative bacteria |
| DE69740108D1 (de) | 1996-12-20 | 2011-03-10 | Univ Texas | Moraxella catarrhalis antigene uspa1 und uspa2 |
| GB9810084D0 (en) | 1998-05-11 | 1998-07-08 | Cortecs Uk Ltd | Proteins |
| AU4260099A (en) * | 1998-05-12 | 1999-11-29 | Smithkline Beecham Biologicals (Sa) | Compounds from moraxella catarrhalis |
| GB9810285D0 (en) * | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
| GB9812440D0 (en) * | 1998-06-09 | 1998-08-05 | Smithkline Beecham Biolog | Novel compounds |
| EP1162999B1 (en) | 1999-03-19 | 2006-11-29 | Glaxosmithkline Biologicals S.A. | Vaccine against Streptococcus pneumoniae |
| GB9914945D0 (en) * | 1999-06-25 | 1999-08-25 | Smithkline Beecham Biolog | Novel compounds |
| GB9921691D0 (en) * | 1999-09-14 | 1999-11-17 | Smithkline Beecham Sa | Novel compounds |
| GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| GB0103171D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| PL375408A1 (en) | 2002-08-02 | 2005-11-28 | Glaxosmithkline Biologicals S.A. | Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| KR101730748B1 (ko) | 2005-04-08 | 2017-04-26 | 와이어쓰 엘엘씨 | 다가 폐렴구균 다당류-단백질 접합체 조성물 |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| DK3017827T3 (en) | 2005-12-22 | 2019-02-18 | Glaxosmithkline Biologicals Sa | Pneumococcal polysaccharide conjugate VACCINE |
| KR20080096775A (ko) | 2006-01-17 | 2008-11-03 | 아르네 포르스그렌 | 표면 노출된 헤모필루스 인플루엔자 단백질 （단백질 Ｅ ―ｐＥ） |
| WO2009000826A1 (en) | 2007-06-26 | 2008-12-31 | Glaxosmithkline Biologicals S.A. | Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates |
| UA99659C2 (uk) | 2008-05-30 | 2012-09-10 | Дзе Ю.Ес.Ей., Ес Репрезентед Бай Дзе Секретарі Оф Дзе Армі, Он Бехаф Оф Уолтер Рід Армі | Мультивалентна вакцина з нативних везикул зовнішньої мембрани менінгококів, способи її застосування |
| GB201003922D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Conjugation process |
| GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| CN102869378A (zh) | 2010-03-10 | 2013-01-09 | 葛兰素史密丝克莱恩生物有限公司 | 免疫原性组合物 |
| GB201103836D0 (en) | 2011-03-07 | 2011-04-20 | Glaxosmithkline Biolog Sa | Conjugation process |
| GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| GB201621686D0 (en) | 2016-12-20 | 2017-02-01 | Glaxosmithkline Biologicals Sa | Novel methods for inducing an immune response |
| GB2600653B (en) | 2017-05-30 | 2022-11-02 | Glaxosmithkline Biologicals Sa | Novel methods |
| MX2020005481A (es) | 2017-12-01 | 2020-12-07 | Glaxosmithkline Biologicals Sa | Purificacion de saponina. |
| BR112021000965A2 (pt) | 2018-08-07 | 2021-04-27 | Glaxosmithkline Biologicals S.A. | processos e vacinas |
| US20220339282A1 (en) | 2018-11-29 | 2022-10-27 | Glaxosmithkline Biologicals Sa | Methods for manufacturing an adjuvant |
| CA3142300A1 (en) | 2019-06-05 | 2020-12-10 | Glaxosmithkline Biologicals Sa | Saponin purification |
| GB202205833D0 (en) | 2022-04-21 | 2022-06-08 | Glaxosmithkline Biologicals Sa | Bacteriophage |
| WO2024017827A1 (en) | 2022-07-19 | 2024-01-25 | Glaxosmithkline Biologicals Sa | Continuous process for vaccine production |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5030556A (en) * | 1989-03-30 | 1991-07-09 | Danielle Beaulieu | Species-specific DNNA probe for the detection of Branhamella catarrhalis |
-
1991
- 1991-08-15 US US07/745,591 patent/US5552146A/en not_active Expired - Lifetime
-
1992
- 1992-08-14 AU AU24878/92A patent/AU666329B2/en not_active Ceased
- 1992-08-14 WO PCT/US1992/006869 patent/WO1993003761A1/en active IP Right Grant
- 1992-08-14 EP EP92918273A patent/EP0612250B1/en not_active Expired - Lifetime
- 1992-08-14 JP JP50448193A patent/JP3499868B2/ja not_active Expired - Fee Related
- 1992-08-14 AT AT92918273T patent/ATE140627T1/de not_active IP Right Cessation
- 1992-08-14 ES ES92918273T patent/ES2092696T3/es not_active Expired - Lifetime
- 1992-08-14 CA CA002115565A patent/CA2115565C/en not_active Expired - Fee Related
- 1992-08-14 DE DE69212495T patent/DE69212495T2/de not_active Expired - Fee Related
- 1992-08-14 KR KR1019940700431A patent/KR100271888B1/ko not_active IP Right Cessation
- 1992-08-14 DK DK92918273.1T patent/DK0612250T3/da active
-
1994
- 1994-02-14 NO NO940502A patent/NO308413B1/no unknown
- 1994-02-14 FI FI940681A patent/FI106844B/fi active
- 1994-09-19 US US08/193,150 patent/US5759813A/en not_active Expired - Fee Related
-
1995
- 1995-05-25 US US08/450,002 patent/US5599693A/en not_active Expired - Lifetime
-
1996
- 1996-10-23 GR GR960402795T patent/GR3021423T3/el unknown
-
2000
- 2000-05-09 NO NO20002413A patent/NO20002413L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20002413D0 (no) | 2000-05-09 |
| US5759813A (en) | 1998-06-02 |
| WO1993003761A1 (en) | 1993-03-04 |
| ATE140627T1 (de) | 1996-08-15 |
| FI940681A (fi) | 1994-04-07 |
| GR3021423T3 (en) | 1997-01-31 |
| AU666329B2 (en) | 1996-02-08 |
| DE69212495D1 (de) | 1996-08-29 |
| NO20002413L (no) | 2000-05-09 |
| JP3499868B2 (ja) | 2004-02-23 |
| NO940502D0 (no) | 1994-02-14 |
| NO940502L (no) | 1994-03-28 |
| US5552146A (en) | 1996-09-03 |
| US5599693A (en) | 1997-02-04 |
| FI940681A0 (fi) | 1994-02-14 |
| ES2092696T3 (es) | 1996-12-01 |
| EP0612250B1 (en) | 1996-07-24 |
| EP0612250A1 (en) | 1994-08-31 |
| KR100271888B1 (ko) | 2000-11-15 |
| DK0612250T3 (da) | 1996-11-25 |
| JPH07501210A (ja) | 1995-02-09 |
| CA2115565C (en) | 2007-08-07 |
| DE69212495T2 (de) | 1997-03-06 |
| AU2487892A (en) | 1993-03-16 |
| CA2115565A1 (en) | 1993-03-04 |
| NO308413B1 (no) | 2000-09-11 |
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