DE69212495D1 - Verfahren und zusammensetzungen im hinblick auf nützliche moraxella catarrhalis antigene - Google Patents
Verfahren und zusammensetzungen im hinblick auf nützliche moraxella catarrhalis antigeneInfo
- Publication number
- DE69212495D1 DE69212495D1 DE69212495T DE69212495T DE69212495D1 DE 69212495 D1 DE69212495 D1 DE 69212495D1 DE 69212495 T DE69212495 T DE 69212495T DE 69212495 T DE69212495 T DE 69212495T DE 69212495 D1 DE69212495 D1 DE 69212495D1
- Authority
- DE
- Germany
- Prior art keywords
- omps
- moraxella catarrhalis
- proteins
- variants
- well
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241000588655 Moraxella catarrhalis Species 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108020004414 DNA Proteins 0.000 abstract 1
- 108010052285 Membrane Proteins Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
- C07K14/212—Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/745,591 US5552146A (en) | 1991-08-15 | 1991-08-15 | Methods and compositions relating to useful antigens of Moraxella catarrhalis |
PCT/US1992/006869 WO1993003761A1 (en) | 1991-08-15 | 1992-08-14 | METHODS AND COMPOSITIONS RELATING TO USEFUL ANTIGENS OF $i(MORAXELLA CATARRHALIS) |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69212495D1 true DE69212495D1 (de) | 1996-08-29 |
DE69212495T2 DE69212495T2 (de) | 1997-03-06 |
Family
ID=24997358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69212495T Expired - Fee Related DE69212495T2 (de) | 1991-08-15 | 1992-08-14 | Verfahren und zusammensetzungen im hinblick auf nützliche moraxella catarrhalis antigene |
Country Status (14)
Country | Link |
---|---|
US (3) | US5552146A (de) |
EP (1) | EP0612250B1 (de) |
JP (1) | JP3499868B2 (de) |
KR (1) | KR100271888B1 (de) |
AT (1) | ATE140627T1 (de) |
AU (1) | AU666329B2 (de) |
CA (1) | CA2115565C (de) |
DE (1) | DE69212495T2 (de) |
DK (1) | DK0612250T3 (de) |
ES (1) | ES2092696T3 (de) |
FI (1) | FI106844B (de) |
GR (1) | GR3021423T3 (de) |
NO (2) | NO308413B1 (de) |
WO (1) | WO1993003761A1 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2693654B1 (fr) * | 1992-07-20 | 1994-08-26 | Oreal | Médicament, notamment immunomodulateur, contenant des enveloppes ou fractions d'enveloppes de bactéries filamenteuses non photosynthétiques et non fructifiantes, et sa préparation. |
DK0624376T3 (da) * | 1993-05-13 | 2000-07-24 | American Cyanamid Co | Fremstilling og anvendelse af LOS-udtømte ydre membranproteiner af gram-negative cocci |
US5712118A (en) * | 1993-09-29 | 1998-01-27 | Research Foundation Of State University Of New York | Vaccine for branhamella catarrhalis |
US5607846A (en) * | 1994-05-17 | 1997-03-04 | Research Foundation Of State University Of New York | Vaccine for moraxella catarrhalis |
US6121427A (en) * | 1994-10-24 | 2000-09-19 | Connaught Laboratories Limited | Major outer membrane protein CD of branhamella |
US6335018B1 (en) | 1995-05-01 | 2002-01-01 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
US6440425B1 (en) * | 1995-05-01 | 2002-08-27 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
US6290970B1 (en) * | 1995-10-11 | 2001-09-18 | Aventis Pasteur Limited | Transferrin receptor protein of Moraxella |
US7341727B1 (en) | 1996-05-03 | 2008-03-11 | Emergent Product Development Gaithersburg Inc. | M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same |
KR100500000B1 (ko) * | 1996-05-03 | 2005-12-12 | 안텍스 바이오로직스 인코퍼레이션 | 모락셀라카타르할리스외측막단백질-16폴리펩티드,이의유전자서열및이의용도 |
US6004562A (en) * | 1996-08-16 | 1999-12-21 | The Research Foundation Of The State University Of New York | Outer membrane protein B1 of Moraxella catarrhalis |
US6558677B2 (en) * | 1996-10-15 | 2003-05-06 | Wendell D. Zollinger | Vaccine against gram negative bacteria |
EP0948625B1 (de) | 1996-12-20 | 2011-01-26 | The Board Of Regents, The University Of Texas System | Moraxella catarrhalis antigene uspa1 und uspa2 |
GB9810084D0 (en) | 1998-05-11 | 1998-07-08 | Cortecs Uk Ltd | Proteins |
US6627728B1 (en) | 1998-05-12 | 2003-09-30 | Smithkline Beecham Biologicals S.A. | Compounds from moraxella catarrhalis |
GB9810285D0 (en) | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
GB9812440D0 (en) * | 1998-06-09 | 1998-08-05 | Smithkline Beecham Biolog | Novel compounds |
WO2000056360A2 (en) | 1999-03-19 | 2000-09-28 | Smithkline Beecham Biologicals S.A. | Vaccine against antigens from bacteriae |
GB9914945D0 (en) * | 1999-06-25 | 1999-08-25 | Smithkline Beecham Biolog | Novel compounds |
GB9921691D0 (en) | 1999-09-14 | 1999-11-17 | Smithkline Beecham Sa | Novel compounds |
GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
GB0103171D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
EP1961427A3 (de) | 2002-08-02 | 2009-11-04 | GlaxoSmithKline Biologicals S.A. | Neisseria Impfstoffzusammensetzungen, die eine Kombination von Antigenen enthalten |
GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
IL308456A (en) | 2005-04-08 | 2024-01-01 | Wyeth Llc | A multivalent pneumomuroral protein-polysaccharide conjugate preparation |
US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
EP3020411A1 (de) | 2005-12-22 | 2016-05-18 | GlaxoSmithKline Biologicals s.a. | Impfstoff |
EA015561B1 (ru) | 2006-01-17 | 2011-08-30 | Арне Форсгрен | НОВЫЙ ПОВЕРХНОСТНЫЙ БЕЛОК HAEMOPHILUS INFLUENZAE (БЕЛОК E; pE) |
WO2009000825A2 (en) | 2007-06-26 | 2008-12-31 | Glaxosmithkline Biologicals S.A. | Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates |
AU2009262893B2 (en) | 2008-05-30 | 2015-05-21 | The U.S.A., as represented by The Secretary of the Army, on behalf of Walter Reed Army Institute Of Research | Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof |
GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
GB201003922D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Conjugation process |
CN102869378A (zh) | 2010-03-10 | 2013-01-09 | 葛兰素史密丝克莱恩生物有限公司 | 免疫原性组合物 |
GB201103836D0 (en) | 2011-03-07 | 2011-04-20 | Glaxosmithkline Biolog Sa | Conjugation process |
GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
GB201621686D0 (en) | 2016-12-20 | 2017-02-01 | Glaxosmithkline Biologicals Sa | Novel methods for inducing an immune response |
BR112019025193A2 (pt) | 2017-05-30 | 2020-06-23 | Glaxosmithkline Biologicals S.A. | Métodos de fabricação de um adjuvante lipossomal, de fabricação de um concentrado lipossomal, para a preparação de uma composição imunogênica com adjuvante e para a preparação de uma solução, adjuvante lipossomal, composição imunogênica com adjuvante, e, solução |
JP2021504424A (ja) | 2017-12-01 | 2021-02-15 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | サポニン精製 |
BR112021000965A2 (pt) | 2018-08-07 | 2021-04-27 | Glaxosmithkline Biologicals S.A. | processos e vacinas |
US20220339282A1 (en) | 2018-11-29 | 2022-10-27 | Glaxosmithkline Biologicals Sa | Methods for manufacturing an adjuvant |
EP3980044A1 (de) | 2019-06-05 | 2022-04-13 | GlaxoSmithKline Biologicals SA | Saponinreinigung |
GB202205833D0 (en) | 2022-04-21 | 2022-06-08 | Glaxosmithkline Biologicals Sa | Bacteriophage |
WO2024017827A1 (en) | 2022-07-19 | 2024-01-25 | Glaxosmithkline Biologicals Sa | Continuous process for vaccine production |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5030556A (en) * | 1989-03-30 | 1991-07-09 | Danielle Beaulieu | Species-specific DNNA probe for the detection of Branhamella catarrhalis |
-
1991
- 1991-08-15 US US07/745,591 patent/US5552146A/en not_active Expired - Lifetime
-
1992
- 1992-08-14 DK DK92918273.1T patent/DK0612250T3/da active
- 1992-08-14 EP EP92918273A patent/EP0612250B1/de not_active Expired - Lifetime
- 1992-08-14 WO PCT/US1992/006869 patent/WO1993003761A1/en active IP Right Grant
- 1992-08-14 KR KR1019940700431A patent/KR100271888B1/ko not_active IP Right Cessation
- 1992-08-14 JP JP50448193A patent/JP3499868B2/ja not_active Expired - Fee Related
- 1992-08-14 AT AT92918273T patent/ATE140627T1/de not_active IP Right Cessation
- 1992-08-14 CA CA002115565A patent/CA2115565C/en not_active Expired - Fee Related
- 1992-08-14 ES ES92918273T patent/ES2092696T3/es not_active Expired - Lifetime
- 1992-08-14 AU AU24878/92A patent/AU666329B2/en not_active Ceased
- 1992-08-14 DE DE69212495T patent/DE69212495T2/de not_active Expired - Fee Related
-
1994
- 1994-02-14 NO NO940502A patent/NO308413B1/no unknown
- 1994-02-14 FI FI940681A patent/FI106844B/fi active
- 1994-09-19 US US08/193,150 patent/US5759813A/en not_active Expired - Fee Related
-
1995
- 1995-05-25 US US08/450,002 patent/US5599693A/en not_active Expired - Lifetime
-
1996
- 1996-10-23 GR GR960402795T patent/GR3021423T3/el unknown
-
2000
- 2000-05-09 NO NO20002413A patent/NO20002413D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI940681A0 (fi) | 1994-02-14 |
FI940681A (fi) | 1994-04-07 |
NO20002413L (no) | 2000-05-09 |
US5759813A (en) | 1998-06-02 |
AU2487892A (en) | 1993-03-16 |
NO940502L (no) | 1994-03-28 |
NO940502D0 (no) | 1994-02-14 |
FI106844B (fi) | 2001-04-30 |
ES2092696T3 (es) | 1996-12-01 |
US5599693A (en) | 1997-02-04 |
US5552146A (en) | 1996-09-03 |
ATE140627T1 (de) | 1996-08-15 |
CA2115565A1 (en) | 1993-03-04 |
GR3021423T3 (en) | 1997-01-31 |
WO1993003761A1 (en) | 1993-03-04 |
NO20002413D0 (no) | 2000-05-09 |
AU666329B2 (en) | 1996-02-08 |
EP0612250A1 (de) | 1994-08-31 |
CA2115565C (en) | 2007-08-07 |
JPH07501210A (ja) | 1995-02-09 |
KR100271888B1 (ko) | 2000-11-15 |
EP0612250B1 (de) | 1996-07-24 |
DK0612250T3 (da) | 1996-11-25 |
JP3499868B2 (ja) | 2004-02-23 |
DE69212495T2 (de) | 1997-03-06 |
NO308413B1 (no) | 2000-09-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69212495D1 (de) | Verfahren und zusammensetzungen im hinblick auf nützliche moraxella catarrhalis antigene | |
MX9708438A (es) | Proteina principal de la membrana externa de moraxella, de alto peso molecular. | |
ATE497004T1 (de) | Moraxella catarrhalis antigene uspa1 und uspa2 | |
MX9702714A (es) | Produccion de peptidos en plantas como fusiones de proteinas con revestimiento viral. | |
NO924507L (no) | Protein fra haemophilus influenzae | |
FI102382B1 (fi) | Ilmentämisjärjestelmä ihmisen respiratory syncytial -viruksen glykoproteiinien immunogeenisia fragmentteja sisältäviä kimeerisiä glykoproteiineja varten | |
DE69032922D1 (de) | Menschliches intra-akrosomales spermaantigen zur verwendung in einem empfängnisverhütungsimpfstoff | |
IL75455A (en) | Antigenic proteins and antigenic polypeptides obtained from eimeria tenella sporocysts,methods for their preparation and methods for conferring immunity in chickens to diseases caused by eimeria tenella and eimeria necatrix by immunization with said protein or polypeptides | |
JPH05246887A (ja) | グラム陰性菌トキソイド含有抗菌医薬組成物 | |
DK482788A (da) | Vacciner mod og diagnostiske bestemmelser af haemophilus influenzae | |
FI924457A0 (fi) | Kompositioner och behandlingsfoerfarande foer lunginflammation i djur | |
ATA171686A (de) | Verfahren zur herstellung von gegen pseudomonas aeruginosa infektionen wirksamen praeparationen | |
YU12991A (sh) | Rekombinantne vakcine protiv kokcidioze-5-7 eimeria površinski antigen | |
ATE124420T1 (de) | Impfstoffe und testsätze für haemophilus influenzae. | |
NZ309172A (en) | Neutralizing conformational epitopes of chicken anemia virus | |
ATE420951T1 (de) | Schützende epitope von adenylate-zyklase- hämolysin(ac-hly) und ihre verwendung zur behandlung oder verhütung von bordetella- infektionen | |
Mann et al. | Cell surface proteins of Entamoeba histolytica | |
DD295167A1 (de) | Verfahren zur herstellung monoklonaler antikoerper gegen spermaspezifische antigene im molekulargewichtsbereich um 30km kDa |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |