ATE497004T1 - Moraxella catarrhalis antigene uspa1 und uspa2 - Google Patents

Moraxella catarrhalis antigene uspa1 und uspa2

Info

Publication number
ATE497004T1
ATE497004T1 AT97953461T AT97953461T ATE497004T1 AT E497004 T1 ATE497004 T1 AT E497004T1 AT 97953461 T AT97953461 T AT 97953461T AT 97953461 T AT97953461 T AT 97953461T AT E497004 T1 ATE497004 T1 AT E497004T1
Authority
AT
Austria
Prior art keywords
uspa2
uspa1
moraxella catarrhalis
catarrhalis antigens
proteins
Prior art date
Application number
AT97953461T
Other languages
English (en)
Inventor
Eric Hansen
Christoph Aebi
Leslie Cope
Isobel Maciver
Michael Fiske
Ross Fredenburg
Original Assignee
Univ Texas
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Wyeth Corp filed Critical Univ Texas
Application granted granted Critical
Publication of ATE497004T1 publication Critical patent/ATE497004T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C07K14/212—Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT97953461T 1996-12-20 1997-12-19 Moraxella catarrhalis antigene uspa1 und uspa2 ATE497004T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3359896P 1996-12-20 1996-12-20
PCT/US1997/023930 WO1998028333A2 (en) 1996-12-20 1997-12-19 USPA1 AND USPA2 ANTIGENS OF $i(MORAXELLA CATARRHALIS)

Publications (1)

Publication Number Publication Date
ATE497004T1 true ATE497004T1 (de) 2011-02-15

Family

ID=21871324

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97953461T ATE497004T1 (de) 1996-12-20 1997-12-19 Moraxella catarrhalis antigene uspa1 und uspa2

Country Status (11)

Country Link
US (6) US6310190B1 (de)
EP (1) EP0948625B1 (de)
JP (2) JP2001515467A (de)
KR (1) KR100615109B1 (de)
CN (1) CN1159441C (de)
AT (1) ATE497004T1 (de)
AU (2) AU746442B2 (de)
BR (1) BR9714160A (de)
CA (1) CA2274495C (de)
DE (1) DE69740108D1 (de)
WO (1) WO1998028333A2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440425B1 (en) * 1995-05-01 2002-08-27 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US6335018B1 (en) * 1995-05-01 2002-01-01 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
BR9910089A (pt) * 1998-05-01 2004-06-08 Chiron Corp Composições e antìgenos de neisseria meningitidis
GB9817824D0 (en) * 1998-08-14 1998-10-14 Smithkline Beecham Biolog Novel compounds
GB9820002D0 (en) * 1998-09-14 1998-11-04 Smithkline Beecham Biolog Novel compounds
GB9904559D0 (en) 1999-02-26 1999-04-21 Smithkline Beecham Biolog Novel compounds
WO2000061165A1 (en) * 1999-04-13 2000-10-19 Smithkline Beecham Corporation Conserved adhesin motif and methods of use thereof
AU4567300A (en) * 1999-05-24 2000-12-12 Smithkline Beecham Biologicals (Sa) Novel compounds
PT2270030E (pt) 2000-02-28 2012-07-24 Novartis Vaccines & Diagnostic Expressão heteróloga de proteínas de neisseria
MY129765A (en) * 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
WO2002083710A2 (en) * 2001-04-13 2002-10-24 Wyeth Holdings Corporation Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography
US7449302B2 (en) 2002-10-02 2008-11-11 The University Of Bristol, University Walk Therapeutic peptides
GB0222764D0 (en) * 2002-10-02 2002-11-06 Univ Bristol Therapeutic peptide
US7407672B2 (en) * 2002-11-04 2008-08-05 National Heart Center Composition derived from biological materials and method of use and preparation
NZ551204A (en) * 2004-04-15 2010-03-26 Univ Bristol Therapeutic peptides
US7709001B2 (en) 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
CN102716480B (zh) 2005-04-08 2023-03-21 惠氏有限责任公司 多价肺炎球菌多糖-蛋白质缀合物组合物
ES2537274T3 (es) * 2005-08-10 2015-06-05 Arne Forsgren Ab Interacción de Moraxella catarrhalis con células epiteliales, proteínas de la matriz extracelular y el sistema del complemento
US8298544B2 (en) * 2006-02-27 2012-10-30 Gal Markel CEACAM based antibacterial agents
WO2008000918A1 (en) * 2006-06-29 2008-01-03 Suomen Punainen Risti, Veripalvelu Novel cellular glycan compositions
JP5292303B2 (ja) * 2007-11-02 2013-09-18 日本全薬工業株式会社 新規アジュバント
TW201302779A (zh) 2011-04-13 2013-01-16 Glaxosmithkline Biolog Sa 融合蛋白質及組合疫苗
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
UA114503C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
US9120859B2 (en) 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
TW201620927A (zh) * 2014-02-24 2016-06-16 葛蘭素史密斯克藍生物品公司 Ｕｓｐａ２蛋白質構築體及其用途
CN105203754B (zh) * 2014-08-18 2017-02-01 董俊 基于磁性分离和量子点标记的卡他莫拉菌快速检测方法和试剂盒
EP3641808A1 (de) 2017-08-14 2020-04-29 GlaxoSmithKline Biologicals S.A. Verfahren zur verstärkung der immunantwort
GB201803692D0 (en) * 2018-03-08 2018-04-25 Glaxosmithkline Biologicals Sa Immunogenic composition
CN110540594B (zh) * 2018-12-20 2021-05-11 湖北工业大学 基于卡他莫拉菌表面蛋白的乳胶微球免疫层析试纸的制备方法
CN110540964A (zh) * 2018-12-20 2019-12-06 湖北诺美华抗体药物技术有限公司 人卡他莫拉菌表面蛋白单克隆抗体及应用
US20230266317A1 (en) * 2019-09-11 2023-08-24 Glaxosmithkline Biologicals Sa Antigen binding protein and assays

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US5552146A (en) * 1991-08-15 1996-09-03 Board Of Regents, The University Of Texas System Methods and compositions relating to useful antigens of Moraxella catarrhalis
US5279721A (en) 1993-04-22 1994-01-18 Peter Schmid Apparatus and method for an automated electrophoresis system
US6440425B1 (en) 1995-05-01 2002-08-27 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US6335018B1 (en) * 1995-05-01 2002-01-01 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella

Also Published As

Publication number Publication date
KR100615109B1 (ko) 2006-08-22
US7288646B2 (en) 2007-10-30
EP0948625A2 (de) 1999-10-13
US7569683B2 (en) 2009-08-04
US20090118486A1 (en) 2009-05-07
AU746442B2 (en) 2002-05-02
US7576194B2 (en) 2009-08-18
US7344724B2 (en) 2008-03-18
US20090137788A1 (en) 2009-05-28
US6753417B2 (en) 2004-06-22
CN1159441C (zh) 2004-07-28
US20030032772A1 (en) 2003-02-13
AU2011201228A1 (en) 2011-04-14
CN1251611A (zh) 2000-04-26
WO1998028333A2 (en) 1998-07-02
US6310190B1 (en) 2001-10-30
CA2274495A1 (en) 1998-07-02
KR20000057575A (ko) 2000-09-25
EP0948625B1 (de) 2011-01-26
US20050137131A1 (en) 2005-06-23
CA2274495C (en) 2009-06-02
WO1998028333A3 (en) 1999-01-07
DE69740108D1 (de) 2011-03-10
AU5720198A (en) 1998-07-17
JP2009142276A (ja) 2009-07-02
US20050131221A1 (en) 2005-06-16
BR9714160A (pt) 2000-05-02
JP2001515467A (ja) 2001-09-18

Similar Documents

Publication Publication Date Title
ATE497004T1 (de) Moraxella catarrhalis antigene uspa1 und uspa2
FI940681A (fi) Menetelmä ja koostumuksia, jotka liittyvät Moraxella catarrhalisin käyttökelpoisiin antigeeneihin
CN100415871C (zh) 卡他摩拉克菌外膜蛋白—106多肽及其基因序列和用途
DE69526339T2 (de) Monoklonale antikörper, die an den vorläufer des tumorabstossantigen mage-1 anbinden, rekombinantes mage-1, und von mage-1 abgebieteteimmunogene peptide
EA199700248A1 (ru) Выделенный по существу очищенный поверхностный антиген белковой природы neisseria и фрагмент этого антигена
EA200601715A1 (ru) Получение гуманизированных антител в [организме] трансгенных животных
BR9610872A (pt) Proteìna receptora de transferrina de moraxella
ES2147560T3 (es) Epitopos de proteinas del estres.
CO4790101A1 (es) Antigenos superficiales y proteinas utiles en composiciones para el diagnostico y prevencion de la enfermedad de lyme
ATE112783T1 (de) Stressprotein aus bakterien.
RU2004108115A (ru) Рекомбинантные антитела и композиции, а также способы их создания и использования
DK0493446T3 (da) Behandling af autoimmunsygdom.
CA2137280A1 (fr) Clonage du gene codant pour la proteine gp28.5 de toxoplasma gondii; fragments peptidiques de cette proteine et leurs applications
ATE133708T1 (de) Immunogenisches peptid von echinococcus granulosis, dafür kodierende dns sowie diagnostische und therapeutische verwendungen
NZ309172A (en) Neutralizing conformational epitopes of chicken anemia virus
Muthukkaruppan et al. Monoclonal antibodies against Salmonella porins: generation and characterization
ATE246002T1 (de) Membranproteine von leptospira
DK0472706T3 (da) Induktion af beskyttelse mod viral infektion
ES2316576T3 (es) Nueva proteina de union a inmunoglobulina d expuesta sobre la superficie procedente de moraxella catarrhalis.
VAN LEUVEN et al. A mouse monoclonal antibody to human α2-macroglobulin (α2M) crossreacts with α2M from mouse: Epitope mapping and characterization of subunit structure of murine α2M
ATE549348T1 (de) Therapeutische, sich von uspa1 ableitende peptide
Nakao et al. Monoclonal Antibodies against the Third Component (C 3) of Carp Complement
DK0470989T3 (da) Anvendelse af monoklonale anti-beta2 mikroglobulin antistoffer
MX9709851A (es) Epitopes neutralizadores conformacionales del virus de la anemia de pollo.
RU99100323A (ru) ВАКЦИНА, СОДЕРЖАЩАЯ ПЕРОКСИРЕДОКСИН И/ИЛИ β-ТУБУЛИН

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties