FI105276B - Diagnostinen järjestelmä, jossa käytetään peptidejä ja vasta-aineita, jotka inhiboivat verihiutaleadheesiota - Google Patents

Diagnostinen järjestelmä, jossa käytetään peptidejä ja vasta-aineita, jotka inhiboivat verihiutaleadheesiota Download PDF

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Publication number
FI105276B
FI105276B FI891078A FI891078A FI105276B FI 105276 B FI105276 B FI 105276B FI 891078 A FI891078 A FI 891078A FI 891078 A FI891078 A FI 891078A FI 105276 B FI105276 B FI 105276B
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FI
Finland
Prior art keywords
gpiib
pmi
polypeptide
antibody
fibrinogen
Prior art date
Application number
FI891078A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI891078A (fi
FI891078A0 (fi
Inventor
Edward F Plow
Mark H Ginsberg
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Scripps Clinic Res
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Publication of FI891078A publication Critical patent/FI891078A/fi
Publication of FI891078A0 publication Critical patent/FI891078A0/fi
Application granted granted Critical
Publication of FI105276B publication Critical patent/FI105276B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI891078A 1987-07-08 1989-03-07 Diagnostinen järjestelmä, jossa käytetään peptidejä ja vasta-aineita, jotka inhiboivat verihiutaleadheesiota FI105276B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US7095387A 1987-07-08 1987-07-08
US7095387 1987-07-08
US07/175,342 US5114842A (en) 1987-07-08 1988-03-31 Peptides and antibodies that inhibit platelet adhesion
US17534288 1988-03-31
PCT/US1988/002312 WO1989000200A1 (en) 1987-07-08 1988-07-08 Peptides and antibodies that inhibit platelet adhesion
US8802312 1988-07-08

Publications (3)

Publication Number Publication Date
FI891078A FI891078A (fi) 1989-03-07
FI891078A0 FI891078A0 (fi) 1989-03-07
FI105276B true FI105276B (fi) 2000-07-14

Family

ID=26751678

Family Applications (1)

Application Number Title Priority Date Filing Date
FI891078A FI105276B (fi) 1987-07-08 1989-03-07 Diagnostinen järjestelmä, jossa käytetään peptidejä ja vasta-aineita, jotka inhiboivat verihiutaleadheesiota

Country Status (9)

Country Link
US (4) US5114842A (no)
EP (1) EP0326595B1 (no)
JP (3) JP3184878B2 (no)
AT (1) ATE128183T1 (no)
DE (1) DE3854496T2 (no)
DK (1) DK175655B1 (no)
FI (1) FI105276B (no)
NO (1) NO300505B1 (no)
WO (1) WO1989000200A1 (no)

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US5378464A (en) * 1989-03-08 1995-01-03 Board Of Regents Of The University Of Oklahoma Modulation of inflammatory responses by administration of GMP-140 or antibody to GMP-140
US5464778A (en) * 1989-03-08 1995-11-07 Board Of Regents Of The University Of Oklahoma Glycoprotein ligand for P-selectin and methods of use thereof
US5498694A (en) * 1989-05-25 1996-03-12 La Jolla Cancer Research Foundation Peptides of the cytoplasmic domain of integrin
US5384309A (en) * 1989-07-17 1995-01-24 Genentech, Inc. Cyclized peptides and their use as platelet aggregation inhibitors
WO1991001380A1 (fr) * 1989-07-25 1991-02-07 Institut National De La Sante Et De La Recherche Medicale Anticorps monoclonaux diriges contre des proteines impliquees dans les fonctions plaquettaires, leur application en tant qu'agent diagnostique et therapeutique
FR2650186B1 (fr) * 1989-07-25 1992-02-28 Inst Nat Sante Rech Med Anticorps monoclonaux diriges contre des proteines impliquees dans les fonctions plaquettaires. leur application en tant qu'agent diagnostique et therapeutique
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US6309639B1 (en) * 1991-02-05 2001-10-30 The Board Of Regents Of The University Of Oklahoma Method for inhibiting an inflammatory response using antibodies to P-selectin glycoprotein ligand
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US6033667A (en) * 1992-05-05 2000-03-07 Cytel Corporation Method for detecting the presence of P-selectin
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US6884590B1 (en) 1994-02-11 2005-04-26 Cedars-Sinai Medical Center Methods of screening for ulcerative colitis and crohn's disease
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US7074888B1 (en) 1995-03-17 2006-07-11 The Research Foundation Of State University Of New York Mimotopes and anti-mimotopes of human platelet glycoprotein Ib/IX
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EP3595515A4 (en) 2017-03-14 2020-12-30 University of Connecticut BIODEGRADABLE PRESSURE SENSOR
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Also Published As

Publication number Publication date
US5284751A (en) 1994-02-08
DK175655B1 (da) 2005-01-10
EP0326595B1 (en) 1995-09-20
ATE128183T1 (de) 1995-10-15
JPH02500085A (ja) 1990-01-18
JP3541122B2 (ja) 2004-07-07
US5114842A (en) 1992-05-19
JP3184878B2 (ja) 2001-07-09
NO890981D0 (no) 1989-03-07
WO1989000200A1 (en) 1989-01-12
EP0326595A4 (en) 1990-09-05
NO300505B1 (no) 1997-06-09
JP2001190287A (ja) 2001-07-17
NO890981L (no) 1989-05-05
EP0326595A1 (en) 1989-08-09
FI891078A (fi) 1989-03-07
DE3854496T2 (de) 1996-06-13
DK110189A (da) 1989-05-08
JPH10276778A (ja) 1998-10-20
US5498499A (en) 1996-03-12
DK110189D0 (da) 1989-03-07
JP3420747B2 (ja) 2003-06-30
US5470738A (en) 1995-11-28
FI891078A0 (fi) 1989-03-07
DE3854496D1 (de) 1995-10-26

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