FI104717B - Menetelmä terapeuttisesti aktiivisten substituoitujen fenoksi-imidatsoliini- ja fenoksi-tetrahydropyrimidiiniyhdisteiden valmistamiseksi - Google Patents

Menetelmä terapeuttisesti aktiivisten substituoitujen fenoksi-imidatsoliini- ja fenoksi-tetrahydropyrimidiiniyhdisteiden valmistamiseksi Download PDF

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Publication number
FI104717B
FI104717B FI905168A FI905168A FI104717B FI 104717 B FI104717 B FI 104717B FI 905168 A FI905168 A FI 905168A FI 905168 A FI905168 A FI 905168A FI 104717 B FI104717 B FI 104717B
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FI
Finland
Prior art keywords
formula
phenoxy
med
substituted
compounds
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Application number
FI905168A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI905168A0 (fi
Inventor
Mark William Dudley
Jules Freedman
Original Assignee
Merrell Dow Pharma
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Publication of FI905168A0 publication Critical patent/FI905168A0/fi
Application granted granted Critical
Publication of FI104717B publication Critical patent/FI104717B/fi

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI905168A 1989-10-20 1990-10-19 Menetelmä terapeuttisesti aktiivisten substituoitujen fenoksi-imidatsoliini- ja fenoksi-tetrahydropyrimidiiniyhdisteiden valmistamiseksi FI104717B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42442989A 1989-10-20 1989-10-20
US42442989 1989-10-20

Publications (2)

Publication Number Publication Date
FI905168A0 FI905168A0 (fi) 1990-10-19
FI104717B true FI104717B (fi) 2000-03-31

Family

ID=23682608

Family Applications (1)

Application Number Title Priority Date Filing Date
FI905168A FI104717B (fi) 1989-10-20 1990-10-19 Menetelmä terapeuttisesti aktiivisten substituoitujen fenoksi-imidatsoliini- ja fenoksi-tetrahydropyrimidiiniyhdisteiden valmistamiseksi

Country Status (21)

Country Link
EP (1) EP0423802B1 (es)
JP (1) JP3097696B2 (es)
KR (1) KR0182808B1 (es)
CN (1) CN1028099C (es)
AR (1) AR248400A1 (es)
AT (1) ATE126217T1 (es)
AU (1) AU627627B2 (es)
CA (1) CA2027530C (es)
DE (1) DE69021490T2 (es)
DK (1) DK0423802T3 (es)
ES (1) ES2088936T3 (es)
FI (1) FI104717B (es)
GR (1) GR3017775T3 (es)
HU (1) HU207300B (es)
IE (1) IE67049B1 (es)
IL (1) IL96064A (es)
NO (1) NO179367C (es)
NZ (1) NZ235688A (es)
PH (1) PH27290A (es)
PT (1) PT95637B (es)
ZA (1) ZA908234B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2129142A1 (en) * 1992-02-06 1993-08-19 Jules Freedman Arylalkoxyphenoxy-imidazoline compounds
KR100693139B1 (ko) * 2001-04-19 2007-03-13 엘지전자 주식회사 디스크 드라이브의 트레이 진동방지구조
KR100482010B1 (ko) 2002-11-05 2005-04-14 삼성전자주식회사 모니터장치
EP1958507A1 (en) 2007-02-15 2008-08-20 Syngeta Participations AG Chemical compounds
BRPI0812840A2 (pt) * 2007-07-02 2014-12-09 Hoffmann La Roche 2-imidazolinas

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE614596C (de) * 1931-07-10 1935-06-13 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von ?-Glyoxalidinarylmethylolen
US2893993A (en) * 1958-06-17 1959-07-07 Searle & Co 2-aryloxyaralkyl-1, 4, 5, 6-tetrahydropyrimidines
US3897431A (en) * 1969-04-24 1975-07-29 Sterling Drug Inc 2-{8 {60 -Alkoxy-arylmethyl{9 -2-imidazolines and -1,4,5,6-tetrahydropyrimidines
AU3546478A (en) * 1977-04-29 1979-11-01 Ciba Geigy Ag Ectoparasiticides
DE2961710D1 (en) * 1978-10-09 1982-02-18 Ciba Geigy Ag 2-(alpha-phenoxy-alkyl)-imidazolines and their salts, their preparation and use, and agents against phytoparasitic and zooparasitic mites containing them
US4260626A (en) * 1979-03-26 1981-04-07 Richardson-Merrell Inc. Tetrahydro and imidazoline antisecretory compounds
IT1231237B (it) * 1987-09-21 1991-11-26 Angeli Inst Spa Derivati eterociclici

Also Published As

Publication number Publication date
PH27290A (en) 1993-05-04
HU906514D0 (en) 1991-04-29
KR0182808B1 (ko) 1999-05-01
CN1051039A (zh) 1991-05-01
PT95637B (pt) 1998-04-30
ATE126217T1 (de) 1995-08-15
ES2088936T3 (es) 1996-10-01
IE903765A1 (en) 1991-04-24
CN1028099C (zh) 1995-04-05
FI905168A0 (fi) 1990-10-19
EP0423802A1 (en) 1991-04-24
AU6456590A (en) 1991-04-26
NO179367B (no) 1996-06-17
IL96064A0 (en) 1991-07-18
EP0423802B1 (en) 1995-08-09
AR248400A1 (es) 1995-08-18
ZA908234B (en) 1991-08-28
NO904535D0 (no) 1990-10-19
IE67049B1 (en) 1996-02-21
PT95637A (pt) 1991-09-13
CA2027530A1 (en) 1991-04-21
JP3097696B2 (ja) 2000-10-10
AU627627B2 (en) 1992-08-27
HUT55366A (en) 1991-05-28
JPH03135960A (ja) 1991-06-10
DK0423802T3 (da) 1995-09-18
NO179367C (no) 1996-09-25
NO904535L (no) 1991-04-22
KR910007887A (ko) 1991-05-30
IL96064A (en) 1994-11-28
DE69021490T2 (de) 1996-02-01
DE69021490D1 (de) 1995-09-14
GR3017775T3 (en) 1996-01-31
HU207300B (en) 1993-03-29
NZ235688A (en) 1992-02-25
CA2027530C (en) 2001-05-08

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Owner name: MERRELL DOW PHARMACEUTICALS INC.