FI103348B1 - Menetelmä lääkeainesuspension valmistamiseksi - Google Patents

Menetelmä lääkeainesuspension valmistamiseksi

Info

Publication number
FI103348B1
FI103348B1 FI923491A FI923491A FI103348B1 FI 103348 B1 FI103348 B1 FI 103348B1 FI 923491 A FI923491 A FI 923491A FI 923491 A FI923491 A FI 923491A FI 103348 B1 FI103348 B1 FI 103348B1
Authority
FI
Finland
Prior art keywords
preparation
drug suspension
tgh
dme
pentane
Prior art date
Application number
FI923491A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI923491L (fi
FI923491A0 (fi
FI103348B (fi
Inventor
Hans-Hermann Weil
Ottfried Daab
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6399399&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI103348(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of FI923491L publication Critical patent/FI923491L/fi
Publication of FI923491A0 publication Critical patent/FI923491A0/fi
Application granted granted Critical
Publication of FI103348B publication Critical patent/FI103348B/fi
Publication of FI103348B1 publication Critical patent/FI103348B1/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K3/00—Materials not provided for elsewhere
    • C09K3/30—Materials not provided for elsewhere for aerosols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Detergent Compositions (AREA)
FI923491A 1990-02-03 1992-08-03 Menetelmä lääkeainesuspension valmistamiseksi FI103348B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4003270 1990-02-03
DE4003270A DE4003270A1 (de) 1990-02-03 1990-02-03 Neue treibgase und ihre verwendung in arzneimittelzubereitungen
PCT/EP1991/000178 WO1991011496A1 (de) 1990-02-03 1991-01-31 Neue treibgase und ihre verwendung in arzneimittelzubereitungen
EP9100178 1991-01-31

Publications (4)

Publication Number Publication Date
FI923491L FI923491L (fi) 1992-08-03
FI923491A0 FI923491A0 (fi) 1992-08-03
FI103348B FI103348B (fi) 1999-06-15
FI103348B1 true FI103348B1 (fi) 1999-06-15

Family

ID=6399399

Family Applications (1)

Application Number Title Priority Date Filing Date
FI923491A FI103348B1 (fi) 1990-02-03 1992-08-03 Menetelmä lääkeainesuspension valmistamiseksi

Country Status (25)

Country Link
US (7) US6419899B1 (cs)
EP (1) EP0513099B1 (cs)
JP (1) JP3497162B2 (cs)
KR (1) KR920703034A (cs)
AT (1) ATE185587T1 (cs)
AU (1) AU656129B2 (cs)
CA (1) CA2075060C (cs)
CZ (1) CZ285209B6 (cs)
DE (2) DE4003270A1 (cs)
DK (1) DK0513099T3 (cs)
ES (1) ES2139574T3 (cs)
FI (1) FI103348B1 (cs)
GR (1) GR3032176T3 (cs)
HR (1) HRP940737B1 (cs)
HU (1) HU218664B (cs)
IL (1) IL97024A0 (cs)
NO (1) NO302420B1 (cs)
NZ (1) NZ236974A (cs)
PT (1) PT96635B (cs)
RU (1) RU2118170C1 (cs)
SI (1) SI9110155B (cs)
SK (1) SK281440B6 (cs)
WO (1) WO1991011496A1 (cs)
YU (1) YU48509B (cs)
ZA (1) ZA91756B (cs)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4003270A1 (de) 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgase und ihre verwendung in arzneimittelzubereitungen
MX9203481A (es) 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
WO1992006675A1 (en) * 1990-10-18 1992-04-30 Minnesota Mining And Manufacturing Company Aerosol formulation comprising beclomethasone 17,21 dipropionate
DK0656206T3 (da) * 1991-06-10 2001-10-08 Schering Corp Aerosolformuleringer uden chlorfluorcarbonforbindelser
US5221492A (en) * 1991-08-23 1993-06-22 E. I. Du Pont De Nemours And Company Azeotropic mixture of perfluoropropane and dimethyl ether
GB9118830D0 (en) * 1991-09-03 1991-10-16 Minnesota Mining & Mfg Medical aerosol formulations
US5674471A (en) * 1991-12-12 1997-10-07 Glaxo Group Limited Aerosol formulations containing P134a and salbutamol
US5736124A (en) * 1991-12-12 1998-04-07 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicament
ATE171865T1 (de) 1991-12-12 1998-10-15 Glaxo Group Ltd Arzneimittel
US5744123A (en) * 1991-12-12 1998-04-28 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
NZ246046A (en) * 1991-12-12 1995-12-21 Glaxo Group Ltd Aerosol comprising a particulate medicament in a fluorocarbon or chlorofluorohydrocarbon and a polar cosolvent
US5653962A (en) * 1991-12-12 1997-08-05 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5916540A (en) 1994-10-24 1999-06-29 Glaxo Group Limited Aerosol formulations containing P134A and/or P227 and particulate medicament
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
US20030103907A1 (en) * 1991-12-18 2003-06-05 Schultz Robert K. Suspension aerosol formulations
ATE150296T1 (de) * 1991-12-18 1997-04-15 Minnesota Mining & Mfg Aerosolzusammensetzungen für arzneimittelsuspensionen
WO1993019117A1 (en) * 1992-03-26 1993-09-30 Great Lakes Chemical Corporation Azeotrope-like compositions of 1,1,1,2,3,3,3-heptafluoropropane and 1,1-difluoroethane
BR9307627A (pt) * 1992-12-09 1999-06-15 Boehringer Ingelheim Pharma Formulações mediciais estabilizadas em solução aerosol
DK0735884T3 (da) * 1993-12-20 2000-10-09 Minnesota Mining & Mfg Flunisolid-aerosolformuleringer
CN1088580C (zh) 1994-12-22 2002-08-07 阿斯特拉公司 气溶胶药物制剂
US6135628A (en) * 1995-10-13 2000-10-24 Boehringer Ingelheim Pharmceuticals, Inc. Method and apparatus for homogenizing aerosol formulations
US6054488A (en) * 1996-06-11 2000-04-25 3M Innovative Properties Company Medicinal aerosol formulations of formoterol
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
DE19652790A1 (de) * 1996-12-18 1998-06-25 Hermes Fabrik Pharm Praeparate Pharmazeutische Zubereitungen
US6235265B1 (en) * 1998-10-28 2001-05-22 Alliedsignal Inc. Evaporative coolant for topical anesthesia comprising hydrofluorocarbons and/or hydrochlorofluorocarbons
DE19921693A1 (de) * 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
DE10050994A1 (de) * 2000-10-14 2002-04-18 Boehringer Ingelheim Pharma Neue als Arneimittel einsetzbare Anticholinergika sowie Verfahren zu deren Herstellung
US6706726B2 (en) 2000-10-14 2004-03-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anticholinergics which may be used as medicaments as well as processes for preparing them
DE10062712A1 (de) * 2000-12-15 2002-06-20 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden
DE10130371A1 (de) * 2001-06-23 2003-01-02 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US7754242B2 (en) * 2002-03-20 2010-07-13 Alkermes, Inc. Inhalable sustained therapeutic formulations
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
US7273603B2 (en) 2003-07-11 2007-09-25 Boehringer Ingelheim International Gmbh HFC solution formulations containing an anticholinergic
EP1684717A2 (en) * 2003-10-20 2006-08-02 Schering Corporation Pharmaceutical aerosol compositions
PL1809243T5 (pl) * 2004-07-02 2022-12-27 Boehringer Ingelheim International Gmbh Preparaty aerozolowe w postaci zawiesin z tg 227 ea jako propelent aerozolowy
EP1879571A1 (de) * 2005-04-23 2008-01-23 Boehringer Ingelheim International GmbH Arzneimittelkombination für die inhalation enthaltend neben einem anticholinergikum ein betamimetikum und ein steroid
DE102006017320A1 (de) * 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
MX2009008582A (es) 2007-02-11 2009-10-30 Map Pharmaceuticals Inc Metodo para la administracion terapeutica de dihidroergotamina para permitir un rapido alivio de la migraña mientras se minimiza el perfil de efectos secundarios.
EP2282418A3 (en) 2009-06-23 2011-03-09 Alcatel Lucent A station comprising at least two transmit antennas, and a method of transmitting therefrom
WO2014100351A2 (en) 2012-12-21 2014-06-26 Map Pharmaceuticals, Inc. 8'-hydroxy-dihydroergotamine compounds and compositions

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2490764A (en) * 1945-07-04 1949-12-13 Kinetic Chemicals Inc Fluorinated organic compounds
BE555319A (cs) * 1956-03-21 1900-01-01
BE556587A (cs) 1957-01-31 1957-04-11
GB902590A (en) 1960-03-22 1962-08-01 Allied Chem Production of heptafluoropropane
US3095355A (en) * 1961-10-12 1963-06-25 Revlon Aerosol composition
NL289785A (cs) * 1962-11-29
DE1542076A1 (de) * 1966-04-21 1970-03-26 Colgate Palmolive Co Aerosol-Treibmittel
US3369913A (en) * 1967-03-20 1968-02-20 Union Carbide Corp Self-propelling food mixture
DE1719443B2 (de) 1967-10-07 1973-04-05 Suspensions-aerosole und verfahren zu ihrer herstellung
US4044126A (en) * 1972-04-20 1977-08-23 Allen & Hanburys Limited Steroidal aerosol compositions and process for the preparation thereof
IL51314A (en) 1976-01-30 1980-03-31 Fisons Ltd Disodium cromoglycate of low moisture content and pharmaceutical compositions containing it
NL7708731A (nl) * 1976-08-13 1978-02-15 Montedison Spa Werkwijze voor de bereiding van nieuwe drijf- middelsamenstellingen voor aerosolen.
US4174795A (en) * 1977-02-14 1979-11-20 Bohm Leslie E Pannier mounting arrangement for cycles
GB2001334B (en) 1977-07-19 1982-03-03 Fisons Ltd Pressurised aerosol formulation
CA1136547A (en) 1979-03-08 1982-11-30 Song-Ling Lin Aerosol anesthetic compositions
JPS55131096A (en) 1979-03-30 1980-10-11 Daikin Ind Ltd Working fluid for rankine cycle
US4352789A (en) 1980-03-17 1982-10-05 Minnesota Mining And Manufacturing Company Aerosol compositions containing finely divided solid materials
US4352798A (en) * 1980-07-16 1982-10-05 Glaxo Group Limited 11 α-Amino-androstanes
GB8432063D0 (en) * 1984-12-19 1985-01-30 Riker Laboratories Inc Physically modified steroids
GB8501015D0 (en) 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
US4778674A (en) * 1986-05-28 1988-10-18 Richardson-Vicks Inc. Dry aerosol foam
DE3735467A1 (de) 1987-10-20 1989-05-03 Bayer Ag Verfahren zur herstellung von fluorierten c(pfeil abwaerts)4(pfeil abwaerts)- bis c(pfeil abwaerts)6(pfeil abwaerts)-kohlenwasserstoffen und neue cyclische fluorierte kohlenwasserstoffe, sowie die verwendung von fluorierten c(pfeil abwaerts)4(pfeil abwaerts)- bis c(pfeil abwaerts)6(pfeil abwaerts)-kohlenwasserstoffen als treibgas und arbeitsfluessigkeit fuer waermepumpensysteme
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
DE3903336A1 (de) 1989-02-04 1990-08-09 Bayer Ag Verwendung von c(pfeil abwaerts)3(pfeil abwaerts)- bis c(pfeil abwaerts)5(pfeil abwaerts)-polyfluoralkanen als treibgase
DE3905726A1 (de) * 1989-02-24 1990-08-30 Hoechst Ag Druckgaspackung und treibmittel fuer aerosole
JP2642738B2 (ja) 1989-04-13 1997-08-20 ライオン株式会社 人体塗布用エアゾール製品
DE4003270A1 (de) 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgase und ihre verwendung in arzneimittelzubereitungen
IE67185B1 (en) 1990-02-02 1996-03-06 Fisons Plc Propellant compositions
DE4003272A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
US5118494A (en) * 1990-03-23 1992-06-02 Minnesota Mining And Manufacturing Company Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
US5182097A (en) * 1991-02-14 1993-01-26 Virginia Commonwealth University Formulations for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
EP0504112A3 (en) 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
DK0656206T3 (da) 1991-06-10 2001-10-08 Schering Corp Aerosolformuleringer uden chlorfluorcarbonforbindelser
DK1277467T3 (da) 1991-06-10 2007-01-15 Schering Corp Formuleringer af ikke-chlorfluorcarbonaerosoler
US5653962A (en) * 1991-12-12 1997-08-05 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5674471A (en) * 1991-12-12 1997-10-07 Glaxo Group Limited Aerosol formulations containing P134a and salbutamol
ATE137666T1 (de) 1991-12-31 1996-05-15 Hoechst Ag Medizinische aerosolformulierung
GB9425160D0 (en) * 1994-12-10 1995-02-08 Glaxo Group Ltd Medicaments
CN1088580C (zh) 1994-12-22 2002-08-07 阿斯特拉公司 气溶胶药物制剂
TR199701170T1 (xx) * 1995-04-14 1998-02-21 Glaxo Wellcome Inc. Beklometazon dipropionat i�in �l��lm�� doz inhaleri.
WO1998034595A1 (de) 1997-02-05 1998-08-13 Jago Research Ag Medizinische aerosolformulierungen
US5891420A (en) * 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe triancinolone acetonide aerosol formulations for oral inhalation

Also Published As

Publication number Publication date
KR920703034A (ko) 1992-12-17
SI9110155A (sl) 1998-04-30
YU48509B (sh) 1998-09-18
EP0513099B1 (de) 1999-10-13
JPH05504350A (ja) 1993-07-08
FI923491L (fi) 1992-08-03
ATE185587T1 (de) 1999-10-15
EP0513099A1 (de) 1992-11-19
NO302420B1 (no) 1998-03-02
NZ236974A (en) 1993-07-27
IL97024A0 (en) 1992-03-29
RU2118170C1 (ru) 1998-08-27
AU7211691A (en) 1991-08-21
US20050031548A1 (en) 2005-02-10
ES2139574T3 (es) 2000-02-16
SI9110155B (sl) 1999-06-30
NO923040L (no) 1992-07-31
HU218664B (hu) 2000-10-28
YU15591A (sh) 1994-01-20
HUT62455A (en) 1993-05-28
DE59109161D1 (de) 1999-11-18
DK0513099T3 (da) 2000-04-10
GR3032176T3 (en) 2000-04-27
FI923491A0 (fi) 1992-08-03
US7160538B2 (en) 2007-01-09
ZA91756B (en) 1992-10-28
WO1991011496A1 (de) 1991-08-08
PT96635A (pt) 1991-10-31
HU9202508D0 (en) 1992-10-28
US20020071812A1 (en) 2002-06-13
CZ285209B6 (cs) 1999-06-16
DE4003270A1 (de) 1991-08-08
PT96635B (pt) 1998-07-31
US20090104127A1 (en) 2009-04-23
CA2075060A1 (en) 1991-08-04
SK281440B6 (sk) 2001-03-12
CA2075060C (en) 2001-01-02
US20040028618A1 (en) 2004-02-12
FI103348B (fi) 1999-06-15
US6419899B1 (en) 2002-07-16
CS9100265A2 (en) 1991-09-15
US20110014134A1 (en) 2011-01-20
HRP940737B1 (en) 2000-10-31
HK1010737A1 (en) 1999-06-25
AU656129B2 (en) 1995-01-27
HRP940737A2 (en) 1997-06-30
NO923040D0 (no) 1992-07-31
JP3497162B2 (ja) 2004-02-16
US20070065370A1 (en) 2007-03-22

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