FI102190B1 - Menetelmä pesäkkeitä stimuloivan tekijä-1:n uusien muotojen valmistamiseksi ja siinä käytettäviä DNA-sekvenssejä, vektoreita, ilmentämisjärjestelmiä ja rekombinanttisoluja - Google Patents

Menetelmä pesäkkeitä stimuloivan tekijä-1:n uusien muotojen valmistamiseksi ja siinä käytettäviä DNA-sekvenssejä, vektoreita, ilmentämisjärjestelmiä ja rekombinanttisoluja

Info

Publication number
FI102190B1
FI102190B1 FI883056A FI883056A FI102190B1 FI 102190 B1 FI102190 B1 FI 102190B1 FI 883056 A FI883056 A FI 883056A FI 883056 A FI883056 A FI 883056A FI 102190 B1 FI102190 B1 FI 102190B1
Authority
FI
Finland
Prior art keywords
dna sequences
stimulating factor
colony stimulating
vectors
preparation
Prior art date
Application number
FI883056A
Other languages
English (en)
Swedish (sv)
Other versions
FI883056A0 (fi
FI883056A (fi
FI102190B (fi
Inventor
Kirston Edward Koths
Robert Forgan Halenbeck
Ernest Seigo Kawasaki
Martha Ballie Ladner
Mazie Yee Coyne
Arsdell Janelle Nobel Van
George Arthur Martin
Original Assignee
Cetus Oncology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Oncology Corp filed Critical Cetus Oncology Corp
Publication of FI883056A0 publication Critical patent/FI883056A0/fi
Publication of FI883056A publication Critical patent/FI883056A/fi
Application granted granted Critical
Publication of FI102190B1 publication Critical patent/FI102190B1/fi
Publication of FI102190B publication Critical patent/FI102190B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Luminescent Compositions (AREA)
FI883056A 1986-10-24 1988-06-23 Menetelmä pesäkkeitä stimuloivan tekijä-1:n uusien muotojen valmistami seksi ja siinä käytettäviä DNA-sekvenssejä, vektoreita, ilmentämisjärj estelmiä ja rekombinanttisoluja FI102190B (fi)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US92306786A 1986-10-24 1986-10-24
US92306786 1986-10-24
US3965787A 1987-04-16 1987-04-16
US3965487A 1987-04-16 1987-04-16
US3965787 1987-04-16
US3965487 1987-04-16
US8702679 1987-10-16
PCT/US1987/002679 WO1988003173A2 (en) 1986-10-24 1987-10-16 New forms of colony stimulating factor-1

Publications (4)

Publication Number Publication Date
FI883056A0 FI883056A0 (fi) 1988-06-23
FI883056A FI883056A (fi) 1988-06-23
FI102190B1 true FI102190B1 (fi) 1998-10-30
FI102190B FI102190B (fi) 1998-10-30

Family

ID=27365583

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883056A FI102190B (fi) 1986-10-24 1988-06-23 Menetelmä pesäkkeitä stimuloivan tekijä-1:n uusien muotojen valmistami seksi ja siinä käytettäviä DNA-sekvenssejä, vektoreita, ilmentämisjärj estelmiä ja rekombinanttisoluja

Country Status (12)

Country Link
EP (1) EP0272779B1 (fi)
JP (1) JP2644794B2 (fi)
AT (1) ATE105869T1 (fi)
AU (2) AU8007087A (fi)
CA (1) CA1339032C (fi)
DE (1) DE3789859T2 (fi)
DK (1) DK174237B1 (fi)
ES (1) ES2052580T3 (fi)
FI (1) FI102190B (fi)
HU (1) HU215241B (fi)
NO (1) NO301775B1 (fi)
WO (1) WO1988003173A2 (fi)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US6103224A (en) * 1985-02-05 2000-08-15 Chiron Corporation N∇2 CSF-1 (short form) and carboxy truncated fragments thereof
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US6156300A (en) * 1985-02-05 2000-12-05 Chiron Corporation Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
US5573930A (en) 1985-02-05 1996-11-12 Cetus Oncology Corporation DNA encoding various forms of colony stimulating factor-1
AU595864B2 (en) * 1986-03-14 1990-04-12 Otsuka Pharmaceutical Co., Ltd. Il-1 alpha derivatives and drugs
MX9203130A (es) * 1986-05-06 1992-07-01 Genetics Inst Produccion de m-csf
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
JP2583829B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 ヒトｍ−ｃｓｆ
DE3777623D1 (de) * 1986-12-07 1992-04-23 Morinaga Milk Industry Co Ltd Kolonie-stimulierender faktor und verfahren zu seiner herstellung.
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
CA1339757C (en) * 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
CA1317244C (en) * 1987-07-24 1993-05-04 Ernest Seigo Kawasaki Production of biologically active forms of csf using a baculovirus (acnpv)-insect cell expression system
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer
JPH0610137B2 (ja) * 1988-02-29 1994-02-09 新技術事業団 ヒト単球−マクロファージコロニー刺激因子を有効成分とする造血器疾患治療剤
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
EP0410751B1 (en) * 1989-07-27 1996-04-10 Denki Kagaku Kogyo Kabushiki Kaisha Gene encoding M-CSF and related recombinant systems thereof
KR920701253A (ko) * 1989-11-07 1992-08-11 오오쓰까 아끼히꼬 M-csf 유도체, 그 유도체의 발현 벡터, 그 벡터를 갖는 형질 전환체 및 이들의 제조방법
US5714140A (en) * 1989-12-13 1998-02-03 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting the production of bioactive IL-1 by administering M-CSF
DE4014750A1 (de) * 1990-05-08 1991-11-14 Boehringer Mannheim Gmbh Muteine des granulozyten-stimulierenden faktors (g-csf)
AU639091B2 (en) * 1991-04-24 1993-07-15 Otsuka Pharmaceutical Co., Ltd. M-csf derivatives, expression vectors for said derivatives, transformants carrying said vectors and production of these
CA2137793C (en) 1992-06-09 2003-04-22 Jayvardhan Pandit Crystallization of m-csf
JPH08505534A (ja) * 1993-01-13 1996-06-18 森永乳業株式会社 Ｍ−ｃｓｆ２２３の製造方法
GB2355791B (en) 1999-10-28 2004-10-20 Molecular Light Tech Res Ltd Detection of mRNA expression using chemiluminescent labelled probes
KR100371264B1 (ko) * 2000-01-25 2003-02-05 양문식 무라인 그래뉼로사이트-매크로파지 콜로니 자극 인자를포함하는 재조합 벡터와 그것을 발현하는 재조합아스퍼질러스 나이거
ES2591107T3 (es) 2009-10-06 2016-11-24 Regeneron Pharmaceuticals, Inc. Ratones modificados genéticamente e injerto
KR102061143B1 (ko) * 2011-02-15 2019-12-31 리제너론 파마슈티칼스 인코포레이티드 인간화된 ｍ－ｃｓｆ 마우스
CN113897398A (zh) 2012-09-07 2022-01-07 再生元制药公司 经遗传修饰的非人动物及其使用方法
DK3939423T3 (da) 2012-11-05 2024-05-06 Regeneron Pharma Genetisk modificerede ikke-humane dyr og fremgangsmåder til anvendelse deraf
DK3145307T3 (en) 2014-05-19 2019-04-15 Regeneron Pharma RE-MODIFIED NON-HUMAN ANIMALS EXPRESSING HUMAN EPO
ES2950399T3 (es) 2015-04-13 2023-10-09 Regeneron Pharma Ratones humanizados Sirpa-IL15 insertados y métodos de uso de los mismos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3689391T2 (de) * 1985-02-05 1994-06-30 Cetus Oncology Corp Rekombinanter koloniestimulierender faktor-1.
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子

Also Published As

Publication number Publication date
JP2644794B2 (ja) 1997-08-25
FI883056A0 (fi) 1988-06-23
AU646277B2 (en) 1994-02-17
EP0272779A2 (en) 1988-06-29
WO1988003173A2 (en) 1988-05-05
ES2052580T3 (es) 1994-07-16
AU8149491A (en) 1991-10-31
DE3789859D1 (de) 1994-06-23
NO882772D0 (no) 1988-06-22
JPH01501283A (ja) 1989-05-11
CA1339032C (en) 1997-04-01
DE3789859T2 (de) 1994-09-15
FI883056A (fi) 1988-06-23
DK174237B1 (da) 2002-10-07
DK350188A (da) 1988-08-19
EP0272779A3 (en) 1988-08-03
AU8007087A (en) 1988-04-28
HUT47635A (en) 1989-03-28
EP0272779B1 (en) 1994-05-18
WO1988003173A3 (en) 1988-07-28
ATE105869T1 (de) 1994-06-15
DK350188D0 (da) 1988-06-24
FI102190B (fi) 1998-10-30
HU215241B (hu) 1998-11-30
NO882772L (no) 1988-08-22
NO301775B1 (no) 1997-12-08

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Owner name: CETUS ONCOLOGY CORPORATION