DK350188A - Hidtil ukendte kolonistimulerende faktor-1-former - Google Patents

Hidtil ukendte kolonistimulerende faktor-1-former

Info

Publication number
DK350188A
DK350188A DK350188A DK350188A DK350188A DK 350188 A DK350188 A DK 350188A DK 350188 A DK350188 A DK 350188A DK 350188 A DK350188 A DK 350188A DK 350188 A DK350188 A DK 350188A
Authority
DK
Denmark
Prior art keywords
forms
stimulating factor
colony stimulating
unknown
csf
Prior art date
Application number
DK350188A
Other languages
English (en)
Other versions
DK174237B1 (da
DK350188D0 (da
Inventor
Kirston Edward Koths
Mazie Yee Coyne
Robert Forgan Halenbeck
Janelle Nobel Van Arsdell
Ernest Seigo Kawasaki
George Arthur Martin
Martha Ballie Ladner
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of DK350188D0 publication Critical patent/DK350188D0/da
Publication of DK350188A publication Critical patent/DK350188A/da
Application granted granted Critical
Publication of DK174237B1 publication Critical patent/DK174237B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Luminescent Compositions (AREA)
DK198803501A 1986-10-24 1988-06-24 DNA-sekvenser, der koder for N2- eller N3-trunkerede former af den lange form og den korte form af CSF-1 og anvendelse heraf i vektorer, ekspressionssystemer, rekombinante værtsceller, samt en fremgangsmåde til fremstilling...... DK174237B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US92306786A 1986-10-24 1986-10-24
US92306786 1986-10-24
US3965487A 1987-04-16 1987-04-16
US3965787A 1987-04-16 1987-04-16
US3965487 1987-04-16
US3965787 1987-04-16
US8702679 1987-10-16
PCT/US1987/002679 WO1988003173A2 (en) 1986-10-24 1987-10-16 New forms of colony stimulating factor-1

Publications (3)

Publication Number Publication Date
DK350188D0 DK350188D0 (da) 1988-06-24
DK350188A true DK350188A (da) 1988-08-19
DK174237B1 DK174237B1 (da) 2002-10-07

Family

ID=27365583

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198803501A DK174237B1 (da) 1986-10-24 1988-06-24 DNA-sekvenser, der koder for N2- eller N3-trunkerede former af den lange form og den korte form af CSF-1 og anvendelse heraf i vektorer, ekspressionssystemer, rekombinante værtsceller, samt en fremgangsmåde til fremstilling......

Country Status (12)

Country Link
EP (1) EP0272779B1 (da)
JP (1) JP2644794B2 (da)
AT (1) ATE105869T1 (da)
AU (2) AU8007087A (da)
CA (1) CA1339032C (da)
DE (1) DE3789859T2 (da)
DK (1) DK174237B1 (da)
ES (1) ES2052580T3 (da)
FI (1) FI102190B1 (da)
HU (1) HU215241B (da)
NO (1) NO301775B1 (da)
WO (1) WO1988003173A2 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6156300A (en) * 1985-02-05 2000-12-05 Chiron Corporation Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US5573930A (en) * 1985-02-05 1996-11-12 Cetus Oncology Corporation DNA encoding various forms of colony stimulating factor-1
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
US6146851A (en) * 1985-02-05 2000-11-14 Chiron Corporation DNA encoding NV2 (long form) and carboxy truncated fragments thereof
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
AU595864B2 (en) * 1986-03-14 1990-04-12 Otsuka Pharmaceutical Co., Ltd. Il-1 alpha derivatives and drugs
JP2579981B2 (ja) * 1986-05-06 1997-02-12 ジェネティックス・インスチチュート・インコーポレーテッド Ｍ―ｃｓｆの生産方法
JP2583829B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 ヒトｍ−ｃｓｆ
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
DE3777623D1 (de) * 1986-12-07 1992-04-23 Morinaga Milk Industry Co Ltd Kolonie-stimulierender faktor und verfahren zu seiner herstellung.
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
CA1339757C (en) 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
WO1989001038A1 (en) * 1987-07-24 1989-02-09 Cetus Corporation PRODUCTION OF BIOLOGICALLY ACTIVE FORMS OF CSF USING A BACULOVIRUS (AcNPV)-INSECT CELL EXPRESSION SYSTEM
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer
JPH0610137B2 (ja) * 1988-02-29 1994-02-09 新技術事業団 ヒト単球−マクロファージコロニー刺激因子を有効成分とする造血器疾患治療剤
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
EP0410751B1 (en) * 1989-07-27 1996-04-10 Denki Kagaku Kogyo Kabushiki Kaisha Gene encoding M-CSF and related recombinant systems thereof
WO1991006567A1 (en) * 1989-11-07 1991-05-16 Otsuka Pharmaceutical Co., Ltd. M-csf derivative, expression vector of said derivative, product of transformation by said vector, and production of them
US5714140A (en) * 1989-12-13 1998-02-03 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting the production of bioactive IL-1 by administering M-CSF
DE4014750A1 (de) * 1990-05-08 1991-11-14 Boehringer Mannheim Gmbh Muteine des granulozyten-stimulierenden faktors (g-csf)
AU639091B2 (en) * 1991-04-24 1993-07-15 Otsuka Pharmaceutical Co., Ltd. M-csf derivatives, expression vectors for said derivatives, transformants carrying said vectors and production of these
US5866114A (en) * 1992-06-09 1999-02-02 Chiron Corporation Crystallization of M-CSFα
WO1994016075A2 (en) * 1993-01-13 1994-07-21 Genetics Institute, Inc. Process for producing m-csf 223
GB2355791B (en) 1999-10-28 2004-10-20 Molecular Light Tech Res Ltd Detection of mRNA expression using chemiluminescent labelled probes
KR100371264B1 (ko) * 2000-01-25 2003-02-05 양문식 무라인 그래뉼로사이트-매크로파지 콜로니 자극 인자를포함하는 재조합 벡터와 그것을 발현하는 재조합아스퍼질러스 나이거
EP3417701B1 (en) 2009-10-06 2021-12-15 Regeneron Pharmaceuticals, Inc. Genetically modified mice and engraftment
ES2948210T3 (es) 2011-02-15 2023-09-06 Regeneron Pharma Ratones humanizados con M-CSF y uso de los mismos
RU2642319C2 (ru) 2012-09-07 2018-01-24 Йель Юниверсити Генетически модифицированные, не принадлежащие к человеческому роду животные и способ их использования
ES2655442T3 (es) 2012-11-05 2018-02-20 Regeneron Pharmaceuticals, Inc. Animales no humanos modificados genéticamente y métodos de uso de los mismos
DK3841877T5 (da) 2014-05-19 2024-08-19 Regeneron Pharma Genetisk modificeret mus, der eksprimerer human EPO
EP3282835B1 (en) 2015-04-13 2023-05-31 Regeneron Pharmaceuticals, Inc. Humanized sirpa-il15 knockin mice and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986004607A1 (en) * 1985-02-05 1986-08-14 Cetus Corporation Recombinant colony stimulating factor-1
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子

Also Published As

Publication number Publication date
JP2644794B2 (ja) 1997-08-25
HU215241B (hu) 1998-11-30
EP0272779A2 (en) 1988-06-29
WO1988003173A3 (en) 1988-07-28
DK174237B1 (da) 2002-10-07
JPH01501283A (ja) 1989-05-11
EP0272779A3 (en) 1988-08-03
DK350188D0 (da) 1988-06-24
FI102190B (fi) 1998-10-30
ES2052580T3 (es) 1994-07-16
ATE105869T1 (de) 1994-06-15
FI883056A (fi) 1988-06-23
EP0272779B1 (en) 1994-05-18
NO301775B1 (no) 1997-12-08
AU646277B2 (en) 1994-02-17
NO882772D0 (no) 1988-06-22
HUT47635A (en) 1989-03-28
CA1339032C (en) 1997-04-01
AU8149491A (en) 1991-10-31
WO1988003173A2 (en) 1988-05-05
AU8007087A (en) 1988-04-28
DE3789859T2 (de) 1994-09-15
NO882772L (no) 1988-08-22
DE3789859D1 (de) 1994-06-23
FI102190B1 (fi) 1998-10-30
FI883056A0 (fi) 1988-06-23

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

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