ATE127842T1 - Megakaryocytopoietin, seine herstellung und benutzung. - Google Patents

Megakaryocytopoietin, seine herstellung und benutzung.

Info

Publication number
ATE127842T1
ATE127842T1 AT89111714T AT89111714T ATE127842T1 AT E127842 T1 ATE127842 T1 AT E127842T1 AT 89111714 T AT89111714 T AT 89111714T AT 89111714 T AT89111714 T AT 89111714T AT E127842 T1 ATE127842 T1 AT E127842T1
Authority
AT
Austria
Prior art keywords
mkp
megakaryocytopoeitin
megakaryocytopoietin
preparation
methods
Prior art date
Application number
AT89111714T
Other languages
English (en)
Inventor
Soreq Hermona
Zakut Haim
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of ATE127842T1 publication Critical patent/ATE127842T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT89111714T 1988-06-28 1989-06-27 Megakaryocytopoietin, seine herstellung und benutzung. ATE127842T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21262388A 1988-06-28 1988-06-28

Publications (1)

Publication Number Publication Date
ATE127842T1 true ATE127842T1 (de) 1995-09-15

Family

ID=22791800

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89111714T ATE127842T1 (de) 1988-06-28 1989-06-27 Megakaryocytopoietin, seine herstellung und benutzung.

Country Status (4)

Country Link
EP (1) EP0354989B1 (de)
AT (1) ATE127842T1 (de)
DE (1) DE68924222T2 (de)
IL (1) IL90719A0 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5155211A (en) * 1986-09-17 1992-10-13 Massachusetts Institute Of Technology Megakaryocyte stimulatory factor
US5260417A (en) * 1989-04-03 1993-11-09 Genetics Institute, Inc. Megakaryocyte growth promoting activity protein
US5326558A (en) * 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
US6433142B1 (en) 1989-08-08 2002-08-13 Genetics Institute, Llc Megakaryocyte stimulating factors
CA2071479A1 (en) * 1990-10-12 1992-04-13 Pamela Hunt Megakaryocyte maturation factors
EP0591420A1 (de) * 1991-06-28 1994-04-13 New England Deaconess Hospital Eine differenzierte megakaryozyten-zellinie, die neue megakaryozyten-differenzierungsfaktoren produziert
AU4190893A (en) * 1992-07-17 1994-01-20 Suntory Limited Megakaryocyte differentiation factor
CN1107891A (zh) * 1994-03-04 1995-09-06 上海贝特生物技术有限公司 人促巨核细胞生成素及其分离纯化和基因克隆方法及应用
US5766581A (en) * 1994-03-31 1998-06-16 Amgen Inc. Method for treating mammals with monopegylated proteins that stimulates megakaryocyte growth and differentiation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894440A (en) * 1986-09-17 1990-01-16 Massachusetts Institute Of Technology Method of isolating megakaryocyte stimulatory factor

Also Published As

Publication number Publication date
IL90719A0 (en) 1990-01-18
DE68924222D1 (de) 1995-10-19
EP0354989B1 (de) 1995-09-13
EP0354989A1 (de) 1990-02-21
DE68924222T2 (de) 1996-02-15

Similar Documents

Publication Publication Date Title
ATE124959T1 (de) Herstellung und verwendung von nicht- glycosiliertem il-6.
DE3788289D1 (de) Rekombinanter Proteinkomplex mit Humanfaktor-VIII:C-Aktivität, seine Herstellung und Anwendung.
AU687112B2 (en) Methods for increasing extracellular adenosine and for stabilization mast cells
AU8149491A (en) New forms of colony stimulating factor-1
ATE78053T1 (de) Vereinfachtes verfahren zur herstellung von menschlichen lymphokinaktivierten killerzellen.
FI894888A7 (fi) Astaksantiinia tuottavia hiivasoluja, menetelmiä niiden valmistamiseks i ja niiden käyttö
ZA893732B (en) Lyophilization of erythrocytes
PT80300A (de) Herstellung von polypeptiden mit human-gammainterferonaktivitat
DE68914582D1 (de) Endothelin-DNA und ihre Verwendung.
BG49827A3 (bg) Метод за получаване на пречистен биологично активен рекомбинантен човешки колоний стимулиращ фактор
ATE127842T1 (de) Megakaryocytopoietin, seine herstellung und benutzung.
BG60238B1 (bg) Човешки тумор- некротизиращ фактор
DE3785132D1 (de) Herstellung optisch aktiver cyclopropancarbonsaeuren.
ATE95564T1 (de) Aeusseres membranprotein f von pseudomonas aeruginosa.
ATE2442T1 (de) Verfahren zur herstellung von interferon und dabei verwendete kulturmediumzusammensetzung.
DE3881023D1 (de) Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.
SE8505920D0 (sv) New protein and its use
CA2011992A1 (en) Use of human interferon-beta for stimulation of erythropoiesis
JPS5746921A (en) Oral preparation of human blood coagulation factor
ATE68601T1 (de) Reagenz zur bestimmung durch haemagglutination von antikoerpern gegen bakterien-toxine, verfahren zu ihrer herstellung und verwendung.
EP0315118A3 (de) Endothelin kodierendes DNA und dessen Verwendung
ATE109151T1 (de) Substituierte thiacycloalkeno (3,2-b> pyridine, methode zur herstellung, zubereitungen und methode zu ihrer anwendung.
ATE100143T1 (de) Hormone und verfahren zur herstellung, verwendung und pruefung derselben.
DE3850933D1 (de) Anticoagulatorisches Protein PP4-X, seine Herstellung und Verwendung.
DE3783237D1 (de) Satz und methode zur bestimmung der wucherungsaktivitaet von menschlichen tumoren.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties