DE68924222D1 - Megakaryocytopoietin, seine Herstellung und Benutzung. - Google Patents

Megakaryocytopoietin, seine Herstellung und Benutzung.

Info

Publication number
DE68924222D1
DE68924222D1 DE68924222T DE68924222T DE68924222D1 DE 68924222 D1 DE68924222 D1 DE 68924222D1 DE 68924222 T DE68924222 T DE 68924222T DE 68924222 T DE68924222 T DE 68924222T DE 68924222 D1 DE68924222 D1 DE 68924222D1
Authority
DE
Germany
Prior art keywords
mkp
megakaryocytopoeitin
megakaryocytopoietin
production
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68924222T
Other languages
English (en)
Other versions
DE68924222T2 (de
Inventor
Soreq Hermona
Zakut Haim Zakut Haim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Application granted granted Critical
Publication of DE68924222D1 publication Critical patent/DE68924222D1/de
Publication of DE68924222T2 publication Critical patent/DE68924222T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57426—Specifically defined cancers leukemia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
DE68924222T 1988-06-28 1989-06-27 Megakaryocytopoietin, seine Herstellung und Benutzung. Expired - Fee Related DE68924222T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21262388A 1988-06-28 1988-06-28

Publications (2)

Publication Number Publication Date
DE68924222D1 true DE68924222D1 (de) 1995-10-19
DE68924222T2 DE68924222T2 (de) 1996-02-15

Family

ID=22791800

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68924222T Expired - Fee Related DE68924222T2 (de) 1988-06-28 1989-06-27 Megakaryocytopoietin, seine Herstellung und Benutzung.

Country Status (4)

Country Link
EP (1) EP0354989B1 (de)
AT (1) ATE127842T1 (de)
DE (1) DE68924222T2 (de)
IL (1) IL90719A0 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5155211A (en) * 1986-09-17 1992-10-13 Massachusetts Institute Of Technology Megakaryocyte stimulatory factor
US5260417A (en) * 1989-04-03 1993-11-09 Genetics Institute, Inc. Megakaryocyte growth promoting activity protein
US5326558A (en) * 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
US6433142B1 (en) 1989-08-08 2002-08-13 Genetics Institute, Llc Megakaryocyte stimulating factors
WO1992006712A1 (en) * 1990-10-12 1992-04-30 Amgen Inc. Megakaryocyte maturation factors
EP0591420A1 (de) * 1991-06-28 1994-04-13 New England Deaconess Hospital Eine differenzierte megakaryozyten-zellinie, die neue megakaryozyten-differenzierungsfaktoren produziert
AU4190893A (en) * 1992-07-17 1994-01-20 Suntory Limited Megakaryocyte differentiation factor
CN1107891A (zh) * 1994-03-04 1995-09-06 上海贝特生物技术有限公司 人促巨核细胞生成素及其分离纯化和基因克隆方法及应用
YU20095A (sh) * 1994-03-31 1998-08-14 Amgen Inc. Mgdf polipeptidi i postupci za njihovu izradu

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894440A (en) * 1986-09-17 1990-01-16 Massachusetts Institute Of Technology Method of isolating megakaryocyte stimulatory factor

Also Published As

Publication number Publication date
EP0354989A1 (de) 1990-02-21
EP0354989B1 (de) 1995-09-13
DE68924222T2 (de) 1996-02-15
ATE127842T1 (de) 1995-09-15
IL90719A0 (en) 1990-01-18

Similar Documents

Publication Publication Date Title
ATE124959T1 (de) Herstellung und verwendung von nicht- glycosiliertem il-6.
DE3788289T2 (de) Rekombinanter Proteinkomplex mit Humanfaktor-VIII:C-Aktivität, seine Herstellung und Anwendung.
ATE78053T1 (de) Vereinfachtes verfahren zur herstellung von menschlichen lymphokinaktivierten killerzellen.
SE8105657L (sv) Mikrobiell framstellning av humanfibroblastinterferon
JPS648974A (en) Production of skin substitute and obtained skin substitute
ATE69266T1 (de) Verfahren zum herstellung von insulin-vorlaeufern und verfahren zur herstellung von humaninsulin.
FI883056A0 (fi) Nya former av kolonistimulerande faktor-1.
DE68914582T2 (de) Endothelin-DNA und ihre Verwendung.
PT80300A (de) Herstellung von polypeptiden mit human-gammainterferonaktivitat
ES2055048T3 (es) Liofilizacion de eritrocitos y medios para usarse en ella.
ATE78399T1 (de) Verwendung von buspiron zur verbesserung des kurzzeitgedaechtnisses.
DE3586346T2 (de) Mikrobielle herstellung von propionsaeure in mischkultur.
DE3869230D1 (de) Verfahren zur herstellung einer loesung hoher spezifischer volumenaktivitaet von einem protein mit gewebe-plasminogenaktivator (t-pa)-aktivitaet, loesung, enthaltend protein mit t-pa-aktivitaet und verwendung der loesung in der human- und veterinaermedizin.
DE68924222T2 (de) Megakaryocytopoietin, seine Herstellung und Benutzung.
BG60238B1 (bg) Човешки тумор- некротизиращ фактор
ATE95564T1 (de) Aeusseres membranprotein f von pseudomonas aeruginosa.
DE68915899T2 (de) Hemmung von HIV mittels Transformationswachstumsfaktor Beta.
DE3850933D1 (de) Anticoagulatorisches Protein PP4-X, seine Herstellung und Verwendung.
ATE100143T1 (de) Hormone und verfahren zur herstellung, verwendung und pruefung derselben.
JPS6480298A (en) Production of human proapolipoprotein a-i-like protein
DE3783237T2 (de) Satz und methode zur bestimmung der wucherungsaktivitaet von menschlichen tumoren.
ATE57835T1 (de) Biologisch wirksame substanz mit hormonellen eigenschaften, verfahren zu ihrer herstellung und verwendung von histonen fuer medizinische zwecke.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee