ES2055048T3 - Liofilizacion de eritrocitos y medios para usarse en ella. - Google Patents

Liofilizacion de eritrocitos y medios para usarse en ella.

Info

Publication number
ES2055048T3
ES2055048T3 ES89304846T ES89304846T ES2055048T3 ES 2055048 T3 ES2055048 T3 ES 2055048T3 ES 89304846 T ES89304846 T ES 89304846T ES 89304846 T ES89304846 T ES 89304846T ES 2055048 T3 ES2055048 T3 ES 2055048T3
Authority
ES
Spain
Prior art keywords
lyophilization
erythrocytes
blood cells
red blood
pentoses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89304846T
Other languages
English (en)
Inventor
Raymond Paul Goodrich
Christine Marie Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cryopharm Corp
Original Assignee
Cryopharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cryopharm Corp filed Critical Cryopharm Corp
Application granted granted Critical
Publication of ES2055048T3 publication Critical patent/ES2055048T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

SE DESCUBRE UN PROCEDIMIENTO Y UN MEDIO PARA LA LIOFILIZACION DE GLOBULOS ROJOS QUE COMPRENDE EL USO DE SOLUCIONES INCLUYENDO MONOSACARIDOS COMO HEXOSAS Y PENTOSAS Y/O POLIMEROS BIOCOMPATIBLES PARA PERMITIR LA RECONSTRUCCION DE GLOBULOS ROJOS VIABLE.
ES89304846T 1988-05-18 1989-05-12 Liofilizacion de eritrocitos y medios para usarse en ella. Expired - Lifetime ES2055048T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19574588A 1988-05-18 1988-05-18

Publications (1)

Publication Number Publication Date
ES2055048T3 true ES2055048T3 (es) 1994-08-16

Family

ID=22722615

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89304846T Expired - Lifetime ES2055048T3 (es) 1988-05-18 1989-05-12 Liofilizacion de eritrocitos y medios para usarse en ella.

Country Status (8)

Country Link
US (1) US5340592A (es)
EP (1) EP0342879B1 (es)
JP (1) JPH0235078A (es)
AT (1) ATE89167T1 (es)
DE (1) DE68906458T2 (es)
ES (1) ES2055048T3 (es)
IL (1) IL90188A0 (es)
ZA (1) ZA893732B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5153004A (en) * 1989-06-02 1992-10-06 Cryopharm Corporation Freezing and thawing of erythrocytes
US5178884A (en) * 1988-05-18 1993-01-12 Cryopharm Corporation Lyophilized and reconstituted red blood cell compositions
IL90188A0 (en) * 1988-05-18 1989-12-15 Cryopharm Corp Process and medium for the lyophilization of erythrocytes
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
WO1991018504A1 (en) * 1990-05-25 1991-12-12 Cryopharm Corporation Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatible amphipathic polymers
US5690963A (en) * 1995-06-30 1997-11-25 The United States Of America As Represented By The Secretary Of The Navy Freeze dried red blood cells
US5750330A (en) * 1996-06-19 1998-05-12 Litron Laboratories Method and composition for lyophilizing red blood cells
US6436705B1 (en) 1997-02-18 2002-08-20 The United States Of America As Represented By The Secretary Of The Navy Shape stabilized erythrocytes
US6358678B1 (en) 1998-02-11 2002-03-19 The United States Of America As Represented By The Secretary Of The Navy Applications of reversible crosslinking and co-treatment in stabilization and viral inactivations of erythrocytes
EP1082006B1 (en) * 1998-05-26 2006-02-01 Lifecell Corporation Cryopreservation of human red blood cells
AU2002248178A1 (en) * 2000-12-15 2002-08-12 Stratagene Mutant cells with enhanced resistance to desiccation
GB0230152D0 (en) * 2002-12-24 2003-02-05 Sinvent As Product
US20070122344A1 (en) 2005-09-02 2007-05-31 University Of Rochester Medical Center Office Of Technology Transfer Intraoperative determination of nerve location
CA2623666C (en) 2005-09-26 2017-10-24 Lifecell Corporation Dry platelet composition
EP1870649A1 (en) * 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
US20080161744A1 (en) 2006-09-07 2008-07-03 University Of Rochester Medical Center Pre-And Intra-Operative Localization of Penile Sentinel Nodes
US8406860B2 (en) 2008-01-25 2013-03-26 Novadaq Technologies Inc. Method for evaluating blush in myocardial tissue
US10219742B2 (en) 2008-04-14 2019-03-05 Novadaq Technologies ULC Locating and analyzing perforator flaps for plastic and reconstructive surgery
ES2671710T3 (es) 2008-05-02 2018-06-08 Novadaq Technologies ULC Métodos para la producción y uso de eritrocitos cargados con sustancias para la observación y el tratamiento de la hemodinámica microvascular
US10492671B2 (en) 2009-05-08 2019-12-03 Novadaq Technologies ULC Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest
WO2013190391A2 (en) 2012-06-21 2013-12-27 Novadaq Technologies Inc. Quantification and analysis of angiography and perfusion
US20150267210A1 (en) 2012-10-16 2015-09-24 Genebridges Gmbh Electrocompetent cells and preparation thereof
CN110822822B (zh) 2014-06-09 2021-08-24 泰尔茂比司特公司 冻干法
CN107209118B (zh) 2014-09-29 2021-05-28 史赛克欧洲运营有限公司 在自体荧光存在下生物材料中目标荧光团的成像
EP3915467A1 (en) 2014-10-09 2021-12-01 Novadaq Technologies ULC Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography
WO2018145193A1 (en) 2017-02-10 2018-08-16 Novadaq Technologies ULC Open-field handheld fluorescence imaging systems and methods
CA3078625C (en) 2017-10-09 2023-01-17 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same
WO2020185916A1 (en) 2019-03-14 2020-09-17 Terumo Bct Biotechnologies, Llc Lyophilization container fill fixture, system and method of use

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786014A (en) * 1952-09-10 1957-03-19 James L Tullis Platelet preservation
US2875588A (en) * 1953-06-11 1959-03-03 Ohio Commw Eng Co Preservation of red blood cells
US3079919A (en) * 1958-11-10 1963-03-05 Baxter Laboratories Inc Parenteral solution equipment and method
US3228838A (en) * 1959-04-23 1966-01-11 Union Carbide Corp Preservation of biological substances
US3080725A (en) * 1960-08-11 1963-03-12 Union Carbide Corp Method and apparatus for controlled rate cooling and warming of biological substances
US3158283A (en) * 1961-04-24 1964-11-24 Union Carbide Corp Corrugated contained for the low temperature preservation of biological substances
US3303662A (en) * 1963-03-01 1967-02-14 Union Carbide Corp Process for cell preservation
BE643051A (es) * 1963-05-31 1964-05-15
US3347745A (en) * 1963-12-06 1967-10-17 Union Carbide Corp Process for freezing erythrocytes
US3344617A (en) * 1965-02-25 1967-10-03 Union Carbide Corp Apparatus for the preservation of biological substances
GB1144216A (en) * 1965-07-12 1969-03-05 Deering Milliken Res Corp Apparatus for placing empty bobbins on pegs
NL126572C (es) * 1966-03-24
GB1244344A (en) * 1967-11-13 1971-08-25 Abbott Lab Hemagglutination testing procedure employing stabilized and potentiated erythrocytes and a method for their preparation
DE2025718C3 (de) * 1967-11-13 1979-06-13 Abbott Laboratories, Chicago, Ill. (V.St.A.) Verfahren zum Stabilisieren von lyophillsierten Erythrozyten
US3758382A (en) * 1968-07-26 1973-09-11 Us Navy Ve agent process of freezing blood using a hydroxyalkyl starch as cryoprotecti
US3554256A (en) * 1968-11-08 1971-01-12 Dave Champman Goldsmith & Yama Flexible intravenous container
US3677022A (en) * 1969-07-24 1972-07-18 Redeco Method for extending the useful storage period of biological substances such as blood
CA928215A (en) * 1969-08-08 1973-06-12 M. Brake Jon Process for the cryogenic preservation of blood and erythrocytes and products produced thereby
US3915794A (en) * 1973-02-09 1975-10-28 Rit Rech Ind Therapeut Stabilizing compositions for cell-free viruses and cell-free virus preparations containing them
DE2310964A1 (de) * 1973-03-02 1974-09-05 Schering Ag Antigen- bzw. antigen-proteinkonjugatbeschichtete erythrocytenpraeparation
DE2532183C3 (de) * 1975-07-18 1982-03-04 Behringwerke Ag, 3550 Marburg Polyionische isotonische Salzlösung zur Konservierung von Erythrozyten oder zur Perfusion und zur Konservierung von zur Transplantion bestimmter Organen
CA1055932A (en) * 1975-10-22 1979-06-05 Hematech Inc. Blood substitute based on hemoglobin
US4018911A (en) * 1975-11-10 1977-04-19 The United States Of America As Represented By The Secretary Of The Navy Method for large volume freezing and thawing of packed erythrocytes
DE2551208C3 (de) * 1975-11-14 1981-05-27 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung einer stabilen Erythrozyten-Präparation
US4059967A (en) * 1976-02-19 1977-11-29 The Community Blood Council Of Greater New York, Inc. Process for freezing blood platelets
US4132594A (en) * 1976-06-28 1979-01-02 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Gas diffusion liquid storage bag and method of use for storing blood
US4131200A (en) * 1976-07-06 1978-12-26 Union Carbide Corporation Thermoplastic blood bag
US4112070A (en) * 1977-06-08 1978-09-05 Research Corporation Blood preservation system
US4320111A (en) * 1977-06-14 1982-03-16 American Home Products Corporation Immunologic compositions methods of preparation and use
DE2820603A1 (de) * 1978-05-11 1979-11-15 Gersonde Klaus Prof Dr Modifizierte intakte erythrozyten und sie enthaltendes blut bzw. blutkonserven
US4278198A (en) * 1977-11-17 1981-07-14 Baxter Travenol Laboratories, Inc. Flexible collapsible container with a stiffening member
US4243687A (en) * 1979-01-10 1981-01-06 Leo Kline Freeze-dried natural sour dough starter
DE3062393D1 (en) * 1979-03-02 1983-04-28 Unilever Plc Composite ice confections and processes for preparing them
DE2929278A1 (de) * 1979-07-19 1981-01-29 Forschungsgesellschaft Fuer Bi Verfahren zum eingefrieren von zellsuspensionen
US4267269A (en) * 1980-02-05 1981-05-12 Baxter Travenol Laboratories, Inc. Red cell storage solution
JPS577419A (en) * 1980-06-17 1982-01-14 Toshiba Kagaku Kogyo Kk Erythrocyte storing solution
SU932438A1 (ru) * 1980-07-31 1982-05-30 Московский Ордена Трудового Красного Знамени Физико-Технический Институт Перестраиваемый отрезающий оптический фильтр
US4521975A (en) * 1981-05-04 1985-06-11 Marquest Medical Products, Inc. Lyophilizing and forming biologicals having a predetermined unit dosage
JPS589688A (ja) * 1981-07-06 1983-01-20 Toyobo Co Ltd 安定な酵素組成物
JPS58131566A (ja) * 1982-04-28 1983-08-05 Green Cross Corp:The 赤血球凍結乾燥物
DE3225408A1 (de) * 1982-07-07 1984-01-12 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Waessrige loesung zum suspendieren und lagern von zellen, insbesondere erythrozyten
FR2542617B2 (fr) * 1982-07-09 1986-06-06 Rgl Transfusion Sanguine Centr Solution protectrice pour la conservation de cellules fonctionnelles
US4639513A (en) * 1984-02-02 1987-01-27 Cuno Inc. Intravenously injectable immunoglobulin G (IGG) and method for producing same
US4865871A (en) * 1983-08-23 1989-09-12 Board Of Regents The University Of Texas System Method for cryopreparing biological tissue
US4585735A (en) * 1984-07-19 1986-04-29 American National Red Cross Prolonged storage of red blood cells
US5084377A (en) * 1984-09-19 1992-01-28 Larry Rowan Cryogenic suspension method
JPS61155332A (ja) * 1984-12-28 1986-07-15 Chemo Sero Therapeut Res Inst 血液凝固第８因子の処理方法
FR2581289A1 (fr) * 1985-05-06 1986-11-07 Rgl Transfusion Sanguine Centr Solution synthetique pour la conservation prolongee de concentres erythrocytaires
JPH0827283B2 (ja) * 1986-03-10 1996-03-21 財団法人化学及血清療法研究所 免疫凝集反応用組成物
US4806343A (en) * 1986-03-13 1989-02-21 University Of Southwestern Louisiana Cryogenic protectant for proteins
US4731330A (en) * 1986-07-01 1988-03-15 Biotrack, Inc. Whole blood control sample
JPS63106562A (ja) * 1986-10-23 1988-05-11 Green Cross Corp:The 逆受身赤血球凝集反応用試薬
US4764463A (en) * 1986-10-30 1988-08-16 The University Of Tennessee Research Corporation Platelet cyropreservation
US4963362A (en) * 1987-08-07 1990-10-16 Regents Of The University Of Minnesota Freeze-dried liposome mixture containing cyclosporin
US4980277A (en) * 1987-10-16 1990-12-25 Cultor Ltd. Cryoprotectant solution and method
US5192553A (en) * 1987-11-12 1993-03-09 Biocyte Corporation Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use
US5171661A (en) * 1988-05-18 1992-12-15 Cryopharm Corporation Medium for lyophilization of erythrocytes
IL90188A0 (en) * 1988-05-18 1989-12-15 Cryopharm Corp Process and medium for the lyophilization of erythrocytes
US5178884A (en) * 1988-05-18 1993-01-12 Cryopharm Corporation Lyophilized and reconstituted red blood cell compositions
US5043261A (en) * 1989-04-10 1991-08-27 Cryopharm Corporation Lyophilized and reconstituted red blood cell and hemosome compositions
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
US5213814A (en) * 1989-04-10 1993-05-25 Cryopharm Corporation Lyophilized and reconstituted blood platelet compositions
US5153004A (en) * 1989-06-02 1992-10-06 Cryopharm Corporation Freezing and thawing of erythrocytes
US4900780A (en) * 1988-05-25 1990-02-13 Masonic Medical Research Laboratory Acellular resuscitative fluid
DE3817906A1 (de) * 1988-05-26 1989-11-30 Boehringer Mannheim Gmbh Verfahren und behaeltnis zum gefriertrocknen unter sterilen bedingungen
US4874690A (en) * 1988-08-26 1989-10-17 Cryopharm Corporation Lyophilization of red blood cells
EP0356258A3 (en) * 1988-08-26 1990-06-06 Cryopharm Corporation Processes for the lyophilization of red blood cells, together with media for lyophilization
US5059518A (en) * 1988-10-20 1991-10-22 Coulter Corporation Stabilized lyophilized mammalian cells and method of making same
US5030560A (en) * 1988-11-04 1991-07-09 Immucor, Inc. Method for drying mammalian cells for use in solid phase immunoassays and articles incorporating same
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
US5118792A (en) * 1989-05-10 1992-06-02 Dna Plant Technology Corporation Ice crystal growth suppression polypeptides and method of making
GB8920007D0 (en) * 1989-09-05 1989-10-18 Devilbiss Co Spraygun
US4973327A (en) * 1989-11-01 1990-11-27 Cryopharm Blood bag for lyophilization
ATE232737T1 (de) * 1990-04-16 2003-03-15 Baxter Int Methode zur unschädlichmachung viraler und bakterieller blutverunreinigungen
WO1991018504A1 (en) * 1990-05-25 1991-12-12 Cryopharm Corporation Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatible amphipathic polymers
US5145770A (en) * 1990-06-04 1992-09-08 Biosurface Technology, Inc. Cryopreservation of cultured epithelial sheets
JPH05506457A (ja) * 1991-02-15 1993-09-22 クライアファーム　コーポレイション 非哺乳類の有核細胞と血液物質の混合物の凍結乾燥及び再構成法
LU88802A1 (fr) * 1996-08-12 1997-02-13 Az Int Sa Essoreuse pour des bandes a franges ou serpilleres comprenant un panneau presseur a mouvement de translation parallele depourvue de fond pour permettre aux bandes a franges ou serpillieres de la traverser pour pouvoir etre plongee dans le liquide contenu dans un seau sous-adjacent

Also Published As

Publication number Publication date
ZA893732B (en) 1990-02-28
JPH0235078A (ja) 1990-02-05
EP0342879A3 (en) 1990-04-25
US5340592A (en) 1994-08-23
DE68906458T2 (de) 1993-09-09
EP0342879B1 (en) 1993-05-12
ATE89167T1 (de) 1993-05-15
DE68906458D1 (de) 1993-06-17
EP0342879A2 (en) 1989-11-23
IL90188A0 (en) 1989-12-15

Similar Documents

Publication Publication Date Title
ES2055048T3 (es) Liofilizacion de eritrocitos y medios para usarse en ella.
EP0392813A3 (en) Processes for reconstituting lyophilized erythrocytes and/or hemosomes
IL98182A0 (en) Cell compositions and methods for the preparation thereof
EP0356257A3 (en) Processes for the lyophilization of cells including lyophilization media, and methods of reconstituting lyophilized cells
IT8720038A0 (it) Cella per la centrifugazione in continuo del sangue.
NL194909B (nl) Werkwijze voor de bereiding van gepolymeriseerd hemoglobine en celvrij vervangingsmiddel voor rode bloedlichaampjes op basis daarvan.
DE3775973D1 (de) In gelatine eingekapselte zusammensetzung mit kontrollierter freisetzung.
DK97189A (da) Immobiliseringsproces
ES518784A0 (es) Perfeccionamientos introducidos en la fabricacion y estructura de bolsas-recipiente conservantes para fines medicos y similares.
ZA896468B (en) Lyophilization of red blood cells
DE69028144D1 (de) Verfahren zum Lagern von Erythrozyten
JPS56100638A (en) Cation exchange resion and its preparation and its use
ES2125880T3 (es) Composiciones liofilizadas mejoradas de ifosfamida.
IL98269A0 (en) Lyophilized red blood cell compositions and processes and medium for the lyophilization of cells
DK160181C (da) Anvendelse af en varmesteriliserbar vandig oploesning til opbevaring af roede blodlegemer, et sammensat blodposesystem omfattende en pose med en saadan vandig oploesning samt en varmesteriliserbar blodpose af plast til brug i det sammmensatte blodposesystem indeholdende en saadan vandig oploesning
NO860344L (no) Vevskultur og fremstilling i permeable geler.
IL90719A0 (en) Novel nuclei acids and polypeptides encoded thereby
EP0356258A3 (en) Processes for the lyophilization of red blood cells, together with media for lyophilization
BR8901200A (pt) Composicao anti-espuma solida,composicao agroquimica e processo para preparacao das mesmas
SE8306986D0 (sv) Blodfilter
DK163195C (da) Fremgangsmaade til radioaktiv maerkning af blodceller, oploesning til brug ved fremgangsmaaden, fremgangsmaade til fremstilling af oploesningen, og saet til radioaktiv maerkning af blodceller
JPS52151788A (en) Method of preparation immobilized enzyme or microbial cellresin composite
FR2603796B1 (fr) Instrumentation pour la collecte d'embryons, sous laparoscopie, chez les petits ruminants
FR2630456B1 (fr) Milieu de culture, notamment utilisable en culture in vitro et en bacteriologie; son procede de preparation
Kang et al. Studies on the Fusion Mechanism of the Cell (1)

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 342879

Country of ref document: ES