DE68906458D1 - Lyophilisation von erythrozyten und dafuer brauchbare mittel. - Google Patents
Lyophilisation von erythrozyten und dafuer brauchbare mittel.Info
- Publication number
- DE68906458D1 DE68906458D1 DE8989304846T DE68906458T DE68906458D1 DE 68906458 D1 DE68906458 D1 DE 68906458D1 DE 8989304846 T DE8989304846 T DE 8989304846T DE 68906458 T DE68906458 T DE 68906458T DE 68906458 D1 DE68906458 D1 DE 68906458D1
- Authority
- DE
- Germany
- Prior art keywords
- lyophilization
- dafuer
- erythrocytes
- useful agents
- blood cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19574588A | 1988-05-18 | 1988-05-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68906458D1 true DE68906458D1 (de) | 1993-06-17 |
DE68906458T2 DE68906458T2 (de) | 1993-09-09 |
Family
ID=22722615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8989304846T Expired - Fee Related DE68906458T2 (de) | 1988-05-18 | 1989-05-12 | Lyophilisation von erythrozyten und dafuer brauchbare mittel. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5340592A (de) |
EP (1) | EP0342879B1 (de) |
JP (1) | JPH0235078A (de) |
AT (1) | ATE89167T1 (de) |
DE (1) | DE68906458T2 (de) |
ES (1) | ES2055048T3 (de) |
IL (1) | IL90188A0 (de) |
ZA (1) | ZA893732B (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5178884A (en) * | 1988-05-18 | 1993-01-12 | Cryopharm Corporation | Lyophilized and reconstituted red blood cell compositions |
US5153004A (en) * | 1989-06-02 | 1992-10-06 | Cryopharm Corporation | Freezing and thawing of erythrocytes |
IL90188A0 (en) * | 1988-05-18 | 1989-12-15 | Cryopharm Corp | Process and medium for the lyophilization of erythrocytes |
US5045446A (en) * | 1988-08-26 | 1991-09-03 | Cryopharm Corporation | Lyophilization of cells |
CA2062941A1 (en) * | 1990-05-25 | 1991-11-26 | Raymond P. Goodrich, Jr. | Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatable amphipathic polymers |
US5690963A (en) * | 1995-06-30 | 1997-11-25 | The United States Of America As Represented By The Secretary Of The Navy | Freeze dried red blood cells |
US5750330A (en) * | 1996-06-19 | 1998-05-12 | Litron Laboratories | Method and composition for lyophilizing red blood cells |
US6436705B1 (en) | 1997-02-18 | 2002-08-20 | The United States Of America As Represented By The Secretary Of The Navy | Shape stabilized erythrocytes |
US6358678B1 (en) | 1998-02-11 | 2002-03-19 | The United States Of America As Represented By The Secretary Of The Navy | Applications of reversible crosslinking and co-treatment in stabilization and viral inactivations of erythrocytes |
ES2257050T3 (es) * | 1998-05-26 | 2006-07-16 | Lifecell Corporation | Conservacion por el frio de hematies humanos. |
AU2002248178A1 (en) * | 2000-12-15 | 2002-08-12 | Stratagene | Mutant cells with enhanced resistance to desiccation |
GB0230152D0 (en) * | 2002-12-24 | 2003-02-05 | Sinvent As | Product |
US20070122344A1 (en) | 2005-09-02 | 2007-05-31 | University Of Rochester Medical Center Office Of Technology Transfer | Intraoperative determination of nerve location |
ES2668551T3 (es) | 2005-09-26 | 2018-05-18 | Lifecell Corporation | Composición seca de plaquetas |
EP1870649A1 (de) | 2006-06-20 | 2007-12-26 | Octapharma AG | Gefriertocknung zum Erzielen einer bestimmte Restfeuchte durch beschränkte Desorptionsenergiepegeln. |
US20080161744A1 (en) | 2006-09-07 | 2008-07-03 | University Of Rochester Medical Center | Pre-And Intra-Operative Localization of Penile Sentinel Nodes |
US8406860B2 (en) | 2008-01-25 | 2013-03-26 | Novadaq Technologies Inc. | Method for evaluating blush in myocardial tissue |
US10219742B2 (en) | 2008-04-14 | 2019-03-05 | Novadaq Technologies ULC | Locating and analyzing perforator flaps for plastic and reconstructive surgery |
WO2009135178A2 (en) | 2008-05-02 | 2009-11-05 | Flower Robert W | Methods for production and use of substance-loaded erythrocytes (s-les) for observation and treatment of microvascular hemodynamics |
US10492671B2 (en) | 2009-05-08 | 2019-12-03 | Novadaq Technologies ULC | Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest |
CA2914778A1 (en) | 2012-06-21 | 2013-12-27 | Novadaq Technologies Inc. | Quantification and analysis of angiography and perfusion |
CN105209601A (zh) | 2012-10-16 | 2015-12-30 | 基因桥有限责任公司 | 电感受态细胞及其制备 |
WO2015191599A2 (en) | 2014-06-09 | 2015-12-17 | Terumo Bct, Inc. | Lyophilization |
CA2963987A1 (en) | 2014-09-29 | 2016-04-07 | Novadaq Technologies Inc. | Imaging a target fluorophore in a biological material in the presence of autofluorescence |
KR101955134B1 (ko) | 2014-10-09 | 2019-03-06 | 노바다크 테크놀러지즈 유엘씨 | 형광-조정 광전용적맥파 측정기를 사용한 조직 내의 절대적인 혈류의 정량화 |
US11140305B2 (en) | 2017-02-10 | 2021-10-05 | Stryker European Operations Limited | Open-field handheld fluorescence imaging systems and methods |
CN111295094A (zh) | 2017-10-09 | 2020-06-16 | 泰尔茂比司特生物技术有限公司 | 冻干容器及使用冻干容器的方法 |
JP2022525398A (ja) | 2019-03-14 | 2022-05-13 | テルモ ビーシーティー バイオテクノロジーズ,エルエルシー | 凍結乾燥容器用充填治具、システム及び使用方法 |
Family Cites Families (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2786014A (en) * | 1952-09-10 | 1957-03-19 | James L Tullis | Platelet preservation |
US2875588A (en) * | 1953-06-11 | 1959-03-03 | Ohio Commw Eng Co | Preservation of red blood cells |
US3079919A (en) * | 1958-11-10 | 1963-03-05 | Baxter Laboratories Inc | Parenteral solution equipment and method |
US3228838A (en) * | 1959-04-23 | 1966-01-11 | Union Carbide Corp | Preservation of biological substances |
US3080725A (en) * | 1960-08-11 | 1963-03-12 | Union Carbide Corp | Method and apparatus for controlled rate cooling and warming of biological substances |
US3158283A (en) * | 1961-04-24 | 1964-11-24 | Union Carbide Corp | Corrugated contained for the low temperature preservation of biological substances |
US3303662A (en) * | 1963-03-01 | 1967-02-14 | Union Carbide Corp | Process for cell preservation |
BE643051A (de) * | 1963-05-31 | 1964-05-15 | ||
US3347745A (en) * | 1963-12-06 | 1967-10-17 | Union Carbide Corp | Process for freezing erythrocytes |
US3344617A (en) * | 1965-02-25 | 1967-10-03 | Union Carbide Corp | Apparatus for the preservation of biological substances |
GB1144216A (en) * | 1965-07-12 | 1969-03-05 | Deering Milliken Res Corp | Apparatus for placing empty bobbins on pegs |
NL126572C (de) * | 1966-03-24 | |||
GB1244344A (en) * | 1967-11-13 | 1971-08-25 | Abbott Lab | Hemagglutination testing procedure employing stabilized and potentiated erythrocytes and a method for their preparation |
DE2025718C3 (de) * | 1967-11-13 | 1979-06-13 | Abbott Laboratories, Chicago, Ill. (V.St.A.) | Verfahren zum Stabilisieren von lyophillsierten Erythrozyten |
US3758382A (en) * | 1968-07-26 | 1973-09-11 | Us Navy | Ve agent process of freezing blood using a hydroxyalkyl starch as cryoprotecti |
US3554256A (en) * | 1968-11-08 | 1971-01-12 | Dave Champman Goldsmith & Yama | Flexible intravenous container |
US3677022A (en) * | 1969-07-24 | 1972-07-18 | Redeco | Method for extending the useful storage period of biological substances such as blood |
CA928215A (en) * | 1969-08-08 | 1973-06-12 | M. Brake Jon | Process for the cryogenic preservation of blood and erythrocytes and products produced thereby |
US3915794A (en) * | 1973-02-09 | 1975-10-28 | Rit Rech Ind Therapeut | Stabilizing compositions for cell-free viruses and cell-free virus preparations containing them |
DE2310964A1 (de) * | 1973-03-02 | 1974-09-05 | Schering Ag | Antigen- bzw. antigen-proteinkonjugatbeschichtete erythrocytenpraeparation |
DE2532183C3 (de) * | 1975-07-18 | 1982-03-04 | Behringwerke Ag, 3550 Marburg | Polyionische isotonische Salzlösung zur Konservierung von Erythrozyten oder zur Perfusion und zur Konservierung von zur Transplantion bestimmter Organen |
CA1055932A (en) * | 1975-10-22 | 1979-06-05 | Hematech Inc. | Blood substitute based on hemoglobin |
US4018911A (en) * | 1975-11-10 | 1977-04-19 | The United States Of America As Represented By The Secretary Of The Navy | Method for large volume freezing and thawing of packed erythrocytes |
DE2551208C3 (de) * | 1975-11-14 | 1981-05-27 | Behringwerke Ag, 3550 Marburg | Verfahren zur Herstellung einer stabilen Erythrozyten-Präparation |
US4059967A (en) * | 1976-02-19 | 1977-11-29 | The Community Blood Council Of Greater New York, Inc. | Process for freezing blood platelets |
US4132594A (en) * | 1976-06-28 | 1979-01-02 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Gas diffusion liquid storage bag and method of use for storing blood |
US4131200A (en) * | 1976-07-06 | 1978-12-26 | Union Carbide Corporation | Thermoplastic blood bag |
US4112070A (en) * | 1977-06-08 | 1978-09-05 | Research Corporation | Blood preservation system |
US4320111A (en) * | 1977-06-14 | 1982-03-16 | American Home Products Corporation | Immunologic compositions methods of preparation and use |
DE2820603A1 (de) * | 1978-05-11 | 1979-11-15 | Gersonde Klaus Prof Dr | Modifizierte intakte erythrozyten und sie enthaltendes blut bzw. blutkonserven |
US4278198A (en) * | 1977-11-17 | 1981-07-14 | Baxter Travenol Laboratories, Inc. | Flexible collapsible container with a stiffening member |
US4243687A (en) * | 1979-01-10 | 1981-01-06 | Leo Kline | Freeze-dried natural sour dough starter |
AU536000B2 (en) * | 1979-03-02 | 1984-04-12 | Unilever Ltd. | Composite ice confections and their preparation |
DE2929278A1 (de) * | 1979-07-19 | 1981-01-29 | Forschungsgesellschaft Fuer Bi | Verfahren zum eingefrieren von zellsuspensionen |
US4267269A (en) * | 1980-02-05 | 1981-05-12 | Baxter Travenol Laboratories, Inc. | Red cell storage solution |
JPS577419A (en) * | 1980-06-17 | 1982-01-14 | Toshiba Kagaku Kogyo Kk | Erythrocyte storing solution |
SU932438A1 (ru) * | 1980-07-31 | 1982-05-30 | Московский Ордена Трудового Красного Знамени Физико-Технический Институт | Перестраиваемый отрезающий оптический фильтр |
US4521975A (en) * | 1981-05-04 | 1985-06-11 | Marquest Medical Products, Inc. | Lyophilizing and forming biologicals having a predetermined unit dosage |
JPS589688A (ja) * | 1981-07-06 | 1983-01-20 | Toyobo Co Ltd | 安定な酵素組成物 |
JPS58131566A (ja) * | 1982-04-28 | 1983-08-05 | Green Cross Corp:The | 赤血球凍結乾燥物 |
DE3225408A1 (de) * | 1982-07-07 | 1984-01-12 | Biotest-Serum-Institut Gmbh, 6000 Frankfurt | Waessrige loesung zum suspendieren und lagern von zellen, insbesondere erythrozyten |
FR2542617B2 (fr) * | 1982-07-09 | 1986-06-06 | Rgl Transfusion Sanguine Centr | Solution protectrice pour la conservation de cellules fonctionnelles |
US4639513A (en) * | 1984-02-02 | 1987-01-27 | Cuno Inc. | Intravenously injectable immunoglobulin G (IGG) and method for producing same |
US4865871A (en) * | 1983-08-23 | 1989-09-12 | Board Of Regents The University Of Texas System | Method for cryopreparing biological tissue |
US4585735A (en) * | 1984-07-19 | 1986-04-29 | American National Red Cross | Prolonged storage of red blood cells |
US5084377A (en) * | 1984-09-19 | 1992-01-28 | Larry Rowan | Cryogenic suspension method |
JPS61155332A (ja) * | 1984-12-28 | 1986-07-15 | Chemo Sero Therapeut Res Inst | 血液凝固第8因子の処理方法 |
FR2581289A1 (fr) * | 1985-05-06 | 1986-11-07 | Rgl Transfusion Sanguine Centr | Solution synthetique pour la conservation prolongee de concentres erythrocytaires |
JPH0827283B2 (ja) * | 1986-03-10 | 1996-03-21 | 財団法人化学及血清療法研究所 | 免疫凝集反応用組成物 |
US4806343A (en) * | 1986-03-13 | 1989-02-21 | University Of Southwestern Louisiana | Cryogenic protectant for proteins |
US4731330A (en) * | 1986-07-01 | 1988-03-15 | Biotrack, Inc. | Whole blood control sample |
JPS63106562A (ja) * | 1986-10-23 | 1988-05-11 | Green Cross Corp:The | 逆受身赤血球凝集反応用試薬 |
US4764463A (en) * | 1986-10-30 | 1988-08-16 | The University Of Tennessee Research Corporation | Platelet cyropreservation |
US4963362A (en) * | 1987-08-07 | 1990-10-16 | Regents Of The University Of Minnesota | Freeze-dried liposome mixture containing cyclosporin |
US4980277A (en) * | 1987-10-16 | 1990-12-25 | Cultor Ltd. | Cryoprotectant solution and method |
US5192553A (en) * | 1987-11-12 | 1993-03-09 | Biocyte Corporation | Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use |
US5153004A (en) * | 1989-06-02 | 1992-10-06 | Cryopharm Corporation | Freezing and thawing of erythrocytes |
IL90188A0 (en) * | 1988-05-18 | 1989-12-15 | Cryopharm Corp | Process and medium for the lyophilization of erythrocytes |
US5213814A (en) * | 1989-04-10 | 1993-05-25 | Cryopharm Corporation | Lyophilized and reconstituted blood platelet compositions |
US5043261A (en) * | 1989-04-10 | 1991-08-27 | Cryopharm Corporation | Lyophilized and reconstituted red blood cell and hemosome compositions |
US5178884A (en) * | 1988-05-18 | 1993-01-12 | Cryopharm Corporation | Lyophilized and reconstituted red blood cell compositions |
US5045446A (en) * | 1988-08-26 | 1991-09-03 | Cryopharm Corporation | Lyophilization of cells |
US5171661A (en) * | 1988-05-18 | 1992-12-15 | Cryopharm Corporation | Medium for lyophilization of erythrocytes |
US4900780A (en) * | 1988-05-25 | 1990-02-13 | Masonic Medical Research Laboratory | Acellular resuscitative fluid |
DE3817906A1 (de) * | 1988-05-26 | 1989-11-30 | Boehringer Mannheim Gmbh | Verfahren und behaeltnis zum gefriertrocknen unter sterilen bedingungen |
EP0356258A3 (de) * | 1988-08-26 | 1990-06-06 | Cryopharm Corporation | Gefriertrocknungsmethode für rote Blutkörperchen und Mittel dafür |
US4874690A (en) * | 1988-08-26 | 1989-10-17 | Cryopharm Corporation | Lyophilization of red blood cells |
US5059518A (en) * | 1988-10-20 | 1991-10-22 | Coulter Corporation | Stabilized lyophilized mammalian cells and method of making same |
US5030560A (en) * | 1988-11-04 | 1991-07-09 | Immucor, Inc. | Method for drying mammalian cells for use in solid phase immunoassays and articles incorporating same |
GB8903593D0 (en) * | 1989-02-16 | 1989-04-05 | Pafra Ltd | Storage of materials |
US5118792A (en) * | 1989-05-10 | 1992-06-02 | Dna Plant Technology Corporation | Ice crystal growth suppression polypeptides and method of making |
GB8920007D0 (en) * | 1989-09-05 | 1989-10-18 | Devilbiss Co | Spraygun |
US4973327A (en) * | 1989-11-01 | 1990-11-27 | Cryopharm | Blood bag for lyophilization |
WO1991016060A1 (en) * | 1990-04-16 | 1991-10-31 | Cryopharm Corporation | Method of inactivation of viral and bacterial blood contaminants |
CA2062941A1 (en) * | 1990-05-25 | 1991-11-26 | Raymond P. Goodrich, Jr. | Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatable amphipathic polymers |
US5145770A (en) * | 1990-06-04 | 1992-09-08 | Biosurface Technology, Inc. | Cryopreservation of cultured epithelial sheets |
WO1992014360A1 (en) * | 1991-02-15 | 1992-09-03 | Cryopharm Corporation | Method of lyophilization and reconstitution of mixtures of nucleated non-mammalian cells and blood matter |
LU88802A1 (fr) * | 1996-08-12 | 1997-02-13 | Az Int Sa | Essoreuse pour des bandes a franges ou serpilleres comprenant un panneau presseur a mouvement de translation parallele depourvue de fond pour permettre aux bandes a franges ou serpillieres de la traverser pour pouvoir etre plongee dans le liquide contenu dans un seau sous-adjacent |
-
1989
- 1989-05-04 IL IL90188A patent/IL90188A0/xx unknown
- 1989-05-12 DE DE8989304846T patent/DE68906458T2/de not_active Expired - Fee Related
- 1989-05-12 AT AT89304846T patent/ATE89167T1/de not_active IP Right Cessation
- 1989-05-12 EP EP89304846A patent/EP0342879B1/de not_active Expired - Lifetime
- 1989-05-12 ES ES89304846T patent/ES2055048T3/es not_active Expired - Lifetime
- 1989-05-18 ZA ZA893732A patent/ZA893732B/xx unknown
- 1989-05-18 JP JP1125460A patent/JPH0235078A/ja active Pending
-
1991
- 1991-12-30 US US07/815,893 patent/US5340592A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0342879A3 (en) | 1990-04-25 |
ATE89167T1 (de) | 1993-05-15 |
JPH0235078A (ja) | 1990-02-05 |
ES2055048T3 (es) | 1994-08-16 |
EP0342879A2 (de) | 1989-11-23 |
ZA893732B (en) | 1990-02-28 |
IL90188A0 (en) | 1989-12-15 |
US5340592A (en) | 1994-08-23 |
EP0342879B1 (de) | 1993-05-12 |
DE68906458T2 (de) | 1993-09-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: COBE LABORATORIES, INC., LAKEWOOD, COL., US |
|
8328 | Change in the person/name/address of the agent |
Free format text: WUESTHOFF & WUESTHOFF PATENT- UND RECHTSANWAELTE, 81541 MUENCHEN |
|
8339 | Ceased/non-payment of the annual fee |