ES8900226A1 - Procedimiento para preparar anticuerpos anti-idiotipicos - Google Patents

Procedimiento para preparar anticuerpos anti-idiotipicos

Info

Publication number
ES8900226A1
ES8900226A1 ES537459A ES537459A ES8900226A1 ES 8900226 A1 ES8900226 A1 ES 8900226A1 ES 537459 A ES537459 A ES 537459A ES 537459 A ES537459 A ES 537459A ES 8900226 A1 ES8900226 A1 ES 8900226A1
Authority
ES
Spain
Prior art keywords
tumours
immune response
idiotype antibodies
viruses induced
viruses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537459A
Other languages
English (en)
Other versions
ES537459A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wistar Institute of Anatomy and Biology
Original Assignee
Wistar Institute of Anatomy and Biology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27069155&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8900226(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/549,506 external-priority patent/US4731237A/en
Application filed by Wistar Institute of Anatomy and Biology filed Critical Wistar Institute of Anatomy and Biology
Publication of ES537459A0 publication Critical patent/ES537459A0/es
Publication of ES8900226A1 publication Critical patent/ES8900226A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4216—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-viral Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • C07K16/4266—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)

Abstract

COMPRENDEN LAS SIGUIENTES ETAPAS: A) ADMINISTRAR UN ANTICUERPO MONOCLONAL ANTI-TUMORAL O ANTI-VIRAL A UN ANIMAL, EN UN VEHICULO FISIOLOGICAMENTE ADECUADO, TAL COMO SALINA FISIOLOGICAMENTE ESTERIL; Y AISLAR Y PURIFICAR LOS ANTICUERPOS ANTIIDOTIPICOS A PARTIR DEL SUERO DEL ANIMAL; ASI COMO ELUIRLOS PARA PROPORCIONAR UNA SOLUCION SUSTANCIALMENTE LIBRE DE ANTICUERPOS ANTI-ISOTIPICOS; O B) EXPANDIR UN B-LINFOCITO QUE PRODUCE UN ANTICUERPO ANTIDIOTIPICO QUE IDENTIFICA UN EPITOPO, PARCTOPO DE UN ANTICUERPO ANTI-TUMORAL O ANTI-VIRAL. EL B-LINFOCITOS SE OBTENDRA POR INMUNIZACION, DE UN ANIMAL O DE UN PACIENTE, CON UN ANTI CUERPO ANTI-TUMORAL O ANTI-VIRAL MONOCLONAL, RECUPERANDOSE A PARTIR DEL BAZO DEL ANIMAL O POR POSTERIOR INDUCCION IN VITRO; POSTERIORMENTE LOS ANTI-CUERPOS ANTI-IDIOTIPICOS SERAN AISLADOS A PARTIR DE LA FRACCION SOBRENADANTE DEL CULTIVO CELULAR. EL OBJETO DE LA INVENCION ES PROPORCIONAR UN MEDIO INDUCTOR DE RESPUESTA INMUNOLOGICA A TUMORES, EN PARTICULAR SOLIDOS Y VIRUS.
ES537459A 1983-11-07 1984-11-07 Procedimiento para preparar anticuerpos anti-idiotipicos Expired ES8900226A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54950583A 1983-11-07 1983-11-07
US06/549,506 US4731237A (en) 1983-11-07 1983-11-07 Immune response to virus induced by anti-idiotype antibodies

Publications (2)

Publication Number Publication Date
ES537459A0 ES537459A0 (es) 1989-04-16
ES8900226A1 true ES8900226A1 (es) 1989-04-16

Family

ID=27069155

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537459A Expired ES8900226A1 (es) 1983-11-07 1984-11-07 Procedimiento para preparar anticuerpos anti-idiotipicos

Country Status (15)

Country Link
EP (2) EP0291636A1 (es)
JP (1) JP2633807B2 (es)
KR (1) KR910001127B1 (es)
AT (1) ATE45285T1 (es)
AU (1) AU596070B2 (es)
DE (1) DE3479289D1 (es)
DK (2) DK162056C (es)
ES (1) ES8900226A1 (es)
FI (1) FI87734C (es)
HU (1) HU194497B (es)
IL (1) IL73428A (es)
MY (1) MY100952A (es)
NZ (1) NZ210106A (es)
PT (1) PT79455A (es)
WO (1) WO1985002121A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116230A (ja) * 1982-11-29 1984-07-05 ベイロ−・カレツジ・オヴ・メデイスン ウイルス性感染因子に対する免疫応答を生起する抗−イデイオタイプ抗体
AU583473B2 (en) * 1983-04-27 1989-05-04 President And Fellows Of Harvard College Method and products for detection of human t cell leukemia virus
CA1255586A (en) * 1984-07-24 1989-06-13 Hendrik M. Geysen Method of determining mimotopes
WO1986006487A1 (en) * 1985-04-22 1986-11-06 Commonwealth Serum Laboratories Commission Method for determining mimotopes
NZ215865A (en) * 1985-04-22 1988-10-28 Commw Serum Lab Commission Method of determining the active site of a receptor-binding analogue
SE8601645D0 (sv) * 1986-04-11 1986-04-11 Ulf R Nilsson Immunologiskt forfarande
EP0344211A4 (en) * 1987-02-20 1990-03-12 Imclone Systems Inc MONOCLONAL ANTIBODIES IN VACCINE COMPOSITIONS.
AU662539B2 (en) * 1987-03-16 1995-09-07 Roland Keith Mcgready Anti-paratopic antibody as an immunogen
CA1341277C (en) * 1987-03-16 2001-07-31 Roland Keith Mcgready Anti-paratopic antibody and a method of its manufacture
AU1436188A (en) * 1987-04-08 1988-10-13 Synbiotics Corp. Method for the early selection of anti-idiotype antibody internal images
AU635492B2 (en) * 1987-10-13 1993-03-25 Telik, Inc. Method to produce immunodiagnostic reagents
US5217869A (en) * 1987-10-13 1993-06-08 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5227159A (en) * 1989-01-31 1993-07-13 Miller Richard A Anti-idiotype antibodies reactive with shared idiotopes expressed by B cell lymphomas and autoantibodies
US5493009A (en) * 1989-11-14 1996-02-20 New York Medical College Antiidiotypic monoclonal antibodies MK2-23 anti-melanomal antibody 763.74
DE69030172T2 (de) * 1990-01-26 1997-06-19 Immunomedics Inc Impfstoffe gegen Krebs und Infektionskrankheiten
US5969109A (en) * 1990-02-28 1999-10-19 Bona; Constantin Chimeric antibodies comprising antigen binding sites and B and T cell epitopes
JPH07506484A (ja) * 1992-01-29 1995-07-20 サイ−クロン，インコーポレーテッド カルチノーマ関連抗原（ｓｋ１），ｓｋ１に対するモノクローナル抗体，これら抗体を産生する方法及びその使用
US6008327A (en) 1992-03-13 1999-12-28 Akzo Nobel, N.V. Peptides and nucleic acid sequences related to the Epstein Barr virus
DE69334191T2 (de) * 1992-03-13 2008-11-27 bioMérieux B.V. Epstein-Barr-Virus verwandte Peptide und Nukleinsäuresegmente
JPH07504802A (ja) * 1992-03-17 1995-06-01 ノバルティス　アクチェンゲゼルシャフト 遺伝子操作抗体
US5844094A (en) * 1992-09-25 1998-12-01 Commonwealth Scientific And Industrial Research Organization Target binding polypeptide
ATE235514T1 (de) 1994-12-28 2003-04-15 Univ Kentucky Monoklonaler anti-idiotypischer antikörper 3h1 aus maus
US6949244B1 (en) 1995-12-20 2005-09-27 The Board Of Trustees Of The University Of Kentucky Murine monoclonal anti-idiotype antibody 11D10 and methods of use thereof
ATE208403T1 (de) * 1995-05-26 2001-11-15 Merck Patent Gmbh Antiidiotypische antikörper die eine immunantwort gegen den rezeptor für epidermalen wachstumsfaktor induzieren
GB9908533D0 (en) 1999-04-14 1999-06-09 Novartis Ag Organic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4285955A (en) * 1978-10-31 1981-08-25 Bayer Aktiengesellschaft 1,4-Dihydropyridinecarboxylic acids
JPS59116230A (ja) * 1982-11-29 1984-07-05 ベイロ−・カレツジ・オヴ・メデイスン ウイルス性感染因子に対する免疫応答を生起する抗−イデイオタイプ抗体
US4692416A (en) * 1982-12-03 1987-09-08 Yeshiva University Monoclonal antibodies reactive with shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosus

Also Published As

Publication number Publication date
DK310285A (da) 1985-07-05
FI852683L (fi) 1985-07-05
WO1985002121A1 (en) 1985-05-23
HUT38841A (en) 1986-07-28
EP0291636A1 (en) 1988-11-23
AU596070B2 (en) 1990-04-26
EP0141783B2 (en) 1993-06-16
ATE45285T1 (de) 1989-08-15
MY100952A (en) 1991-06-15
PT79455A (en) 1984-12-01
AU3614384A (en) 1985-06-03
DK162056B (da) 1991-09-09
DK162056C (da) 1992-02-17
HU194497B (en) 1988-02-29
JP2633807B2 (ja) 1997-07-23
IL73428A (en) 1991-04-15
FI852683A0 (fi) 1985-07-05
EP0141783A3 (en) 1985-07-03
DK7891A (da) 1991-01-16
EP0141783B1 (en) 1989-08-09
EP0141783A2 (en) 1985-05-15
DK162605B (da) 1991-11-18
IL73428A0 (en) 1985-02-28
JPH07194390A (ja) 1995-08-01
DK310285D0 (da) 1985-07-05
KR850700111A (ko) 1985-10-25
FI87734B (fi) 1992-11-13
KR910001127B1 (ko) 1991-02-25
DE3479289D1 (en) 1989-09-14
FI87734C (fi) 1993-02-25
NZ210106A (en) 1990-05-28
DK7891D0 (da) 1991-01-16
ES537459A0 (es) 1989-04-16

Similar Documents

Publication Publication Date Title
MY100952A (en) Immune response to tumours and viruses induced by anti- idiotype antibodies
EP0597829A4 (en) NEW MONOCLONAL ANTIBODY DRESSES AGAINST A NEW ANTIGEN ASSOCIATED WITH HUMAN TUMORS.
IL76142A0 (en) Monoclonal antibody specific to human carcinoma tumorassociated antigen,hybrid cell lines producing the same and methods for the use thereof
IT1052631B (it) Perfezionamento nelle sedie
IL40895A0 (en) Pyrazolo(1,5a)pyrimidines and their preparation
NZ213293A (en) Monoclonal antibodies used to detect glycosphingo lipids associated with cancer cells
PH23799A (en) Immune response to virus induced by anti-idiotype antibodies
DE3586216D1 (de) Brusttumorassoziiertes antigen und monoklonale antikoerper dazu.
ZA816555B (en) Novel benzoxazolinones,substituted in the 6-position by an amino-alcohol chain or amino-ketone chain,their preparation and their use in pharmaceutical preparations
GB2153364B (en) Lymphokine, monoclonal antibody specific to the lymphokine, and their production and uses
ES509859A0 (es) Perfeccionamientos en aparatos para preparar bebidas gaseosas.
EP0131627A4 (en) SPECIFIC ANTIGENS OF THE CEA FAMILY (CARCINO-EMBRYONIC ANTIGEN), SPECIFIC ANTIBODIES OF THESE ANTIGENS AND THEIR METHODS OF USE.
NL182319B (nl) Bekledingspreparaat.
ZA722876B (en) 2,5-bis-substituted pyrimidines and their preparation
DK480985A (da) Antigen peptidforbindelse
IL69998A0 (en) Disopyramide immunogens,antibodies prepared therefrom,labeled conjugates,and the use of such antibodies and labeled conjugates in immunoassays
IT8423124A0 (it) Dispositivo per produrre rettificature oblique.
KR890010069U (ko) 고주파 가열에 의하여 접착 가능한 지퍼(Zipper)
DK564883D0 (da) Antistoffer med dobbelt specificitet,og fremstilling og anvendelser deraf
BR8201189A (pt) Aparelho para fazer bebida gasosa
IT8284936A0 (it) Sedia trasformabile in scala.
DE3688364D1 (de) Steroidische glycolipide als immunstimulatoren.
CA860860A (en) Forehearths, feeders, and the like, and methods and means of heating them
IT7820976V0 (it) Dispositivo per rettificare le sedi di chiusura di rubinetti e simili.
IT8083388A0 (it) I mobili cuciti.

Legal Events

Date Code Title Description
FD2A Announcement of lapse in spain

Effective date: 20170627