ES8801682A1 - Un procedimiento para la preparacion de nuevos compuestos poliprenilicos - Google Patents

Un procedimiento para la preparacion de nuevos compuestos poliprenilicos

Info

Publication number
ES8801682A1
ES8801682A1 ES557242A ES557242A ES8801682A1 ES 8801682 A1 ES8801682 A1 ES 8801682A1 ES 557242 A ES557242 A ES 557242A ES 557242 A ES557242 A ES 557242A ES 8801682 A1 ES8801682 A1 ES 8801682A1
Authority
ES
Spain
Prior art keywords
preparing
processes
pharmaceutical composition
composition containing
polyprenyl compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557242A
Other languages
English (en)
Other versions
ES557242A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of ES8801682A1 publication Critical patent/ES8801682A1/es
Publication of ES557242A0 publication Critical patent/ES557242A0/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/04Monocyclic monocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/42Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Steroid Compounds (AREA)
  • Polyethers (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS POLIPRENILICOS, DE FORMULA (I), Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES. COMPRENDE LA REACCION DE OXIDACION DE UN COMPUESTO DE FORMULA (II), POR TRATAMIENTO CON UN AGENTE OXIDANTE, TAL COMO PERMANGANATO O HIDROXIDO DE CROMO, EN UN DISOLVENTE COMO AGUA O ACIDO ACETICO, A UNA TEMPERATURA COMPRENDIDA ENTRE LA AMBIENTE Y 100JC, PARA FORMAR UN COMPUESTO DE FORMULA (I), EN LA QUE A Y B E Y Y Z SON HIDROGENO O FORMAN ENLACES SENCILLOS ENTRE LOS ATOMOS DE CARBONO ADYACENTES Y N VALE 0-2. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIHIPERCOLESTEROLEMICOS Y ANTIARTERIOESCLEROTICOS.
ES557242A 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos Expired ES8801682A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60050544A JPH0629218B2 (ja) 1985-03-15 1985-03-15 ポリプレニル系化合物

Publications (2)

Publication Number Publication Date
ES8801682A1 true ES8801682A1 (es) 1988-02-16
ES557242A0 ES557242A0 (es) 1988-02-16

Family

ID=12861949

Family Applications (7)

Application Number Title Priority Date Filing Date
ES552948A Expired ES8800124A1 (es) 1985-03-15 1986-03-12 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos.
ES557242A Expired ES8801682A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos
ES557244A Expired ES8802063A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos
ES557245A Expired ES8802064A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos
ES557243A Expired ES8708240A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos
ES557247A Expired ES8708239A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos
ES557246A Expired ES8708241A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES552948A Expired ES8800124A1 (es) 1985-03-15 1986-03-12 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos.

Family Applications After (5)

Application Number Title Priority Date Filing Date
ES557244A Expired ES8802063A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos
ES557245A Expired ES8802064A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos
ES557243A Expired ES8708240A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos
ES557247A Expired ES8708239A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos
ES557246A Expired ES8708241A1 (es) 1985-03-15 1986-12-04 Un procedimiento para la preparacion de nuevos compuestos poliprenilicos

Country Status (18)

Country Link
US (2) US4788330A (es)
EP (1) EP0194693B1 (es)
JP (1) JPH0629218B2 (es)
KR (1) KR920000877B1 (es)
AT (1) ATE44950T1 (es)
AU (1) AU596577B2 (es)
CA (1) CA1264331A (es)
DE (1) DE3664631D1 (es)
DK (1) DK168432B1 (es)
ES (7) ES8800124A1 (es)
FI (1) FI91392C (es)
GR (1) GR860568B (es)
HU (1) HU197294B (es)
IE (1) IE58413B1 (es)
NZ (1) NZ215480A (es)
PH (1) PH22339A (es)
PT (1) PT82202B (es)
ZA (1) ZA861645B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4714078A (en) * 1984-12-03 1987-12-22 Paluch Bernard R Insert for heated humidifier used in respiratory therapy
US4823787A (en) * 1987-07-09 1989-04-25 Carmeli Adahan Portable ventilator apparatus
US4883821A (en) * 1988-04-13 1989-11-28 Eisai Co., Ltd. Agent for treating hyperuricemia
WO2001080854A1 (fr) * 2000-04-24 2001-11-01 Nikken Chemicals Co., Ltd. Activateurs destines au recepteur active par le proliferateur de peroxisomes
CN100428932C (zh) * 2002-05-17 2008-10-29 日研化学株式会社 TGF-α表达抑制剂
US7314643B2 (en) * 2002-08-20 2008-01-01 Nikken Chemicals Co., Ltd. Soft capsule preparation
JP4886506B2 (ja) * 2004-02-25 2012-02-29 国立大学法人 東京大学 転写因子klf5の活性化抑制作用を有する医薬
FR2882359A1 (fr) * 2005-02-24 2006-08-25 Negma Lerads Soc Par Actions S Derives activateurs de ppar, procede de preparation et application en therapeutique
WO2024187697A1 (zh) * 2023-03-14 2024-09-19 苏州海益生物医药科技有限公司 一种1,4-聚异戊二烯分散体系和药物活性成分及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046305A (en) * 1959-09-24 1962-07-24 Pure Oil Co Process for the production of paralkyl-phenol and para-alkyl-benzoic acid
US3385887A (en) * 1961-02-02 1968-05-28 Boots Pure Drug Co Ltd 4-isobutylphenylacetic acid
US3764621A (en) 1967-04-20 1973-10-09 Du Pont Certain substituted methylbenzoic acids and substituted methycyclohexane carboxylic acids
FR2268791A1 (en) * 1974-04-25 1975-11-21 Nobel Hoechst Chimie Para-alkyl benzoic acid alkanolamine condensate - useful as water-soluble or dispersable corrosion inhibitors for ferrous metals
JPS58225039A (ja) * 1982-06-22 1983-12-27 Eisai Co Ltd ポリプレニル系化合物
JPS59101448A (ja) * 1982-11-30 1984-06-12 Eisai Co Ltd ポリプレニルカルボン酸アミドおよびその製造方法ならびにそれを含有する医薬

Also Published As

Publication number Publication date
DK168432B1 (da) 1994-03-28
ES8802063A1 (es) 1988-03-16
PH22339A (en) 1988-08-12
ES8802064A1 (es) 1988-03-16
ES8708240A1 (es) 1987-10-01
ES8708241A1 (es) 1987-10-01
US4883916A (en) 1989-11-28
US4788330A (en) 1988-11-29
ES557247A0 (es) 1987-10-01
PT82202B (pt) 1988-02-17
EP0194693B1 (en) 1989-07-26
FI91392C (fi) 1994-06-27
AU5448786A (en) 1986-09-18
FI860816A0 (fi) 1986-02-25
DK116386D0 (da) 1986-03-13
PT82202A (en) 1986-04-01
EP0194693A1 (en) 1986-09-17
ES557242A0 (es) 1988-02-16
GR860568B (en) 1986-07-10
ES8800124A1 (es) 1987-11-01
ES557244A0 (es) 1988-03-16
HU197294B (en) 1989-03-28
ATE44950T1 (de) 1989-08-15
ES8708239A1 (es) 1987-10-01
DK116386A (da) 1986-09-16
ZA861645B (en) 1986-10-29
ES557245A0 (es) 1988-03-16
JPS61210050A (ja) 1986-09-18
KR920000877B1 (ko) 1992-01-30
IE860568L (en) 1986-09-15
FI860816A (fi) 1986-09-16
ES557243A0 (es) 1987-10-01
CA1264331A (en) 1990-01-09
ES557246A0 (es) 1987-10-01
KR860007191A (ko) 1986-10-08
DE3664631D1 (en) 1989-08-31
AU596577B2 (en) 1990-05-10
JPH0629218B2 (ja) 1994-04-20
ES552948A0 (es) 1987-11-01
IE58413B1 (en) 1993-09-22
FI91392B (fi) 1994-03-15
NZ215480A (en) 1989-07-27
HUT40066A (en) 1986-11-28

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