ES8802064A1 - Un procedimiento para la preparacion de nuevos compuestos poliprenilicos - Google Patents
Un procedimiento para la preparacion de nuevos compuestos poliprenilicosInfo
- Publication number
- ES8802064A1 ES8802064A1 ES557245A ES557245A ES8802064A1 ES 8802064 A1 ES8802064 A1 ES 8802064A1 ES 557245 A ES557245 A ES 557245A ES 557245 A ES557245 A ES 557245A ES 8802064 A1 ES8802064 A1 ES 8802064A1
- Authority
- ES
- Spain
- Prior art keywords
- preparing
- processes
- pharmaceutical composition
- composition containing
- polyprenyl compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/04—Monocyclic monocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/42—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Steroid Compounds (AREA)
- Polyethers (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS POLIPRENILICOS, DE FORMULA (I), Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES. COMPRENDE LA REACCION DE HIDROLISIS DE UN COMPUESTO DE FORMULA (II) POR TRATAMIENTO CON UNA BASE, TAL COMO HIDROXIDO SODICO O POTASICO, EN UN DISOLVENTE TAL COMO PROPILENGLICOL O ETILENGLICOL, A UNA TEMPERATURA COMPRENDIDA ENTRE 80JC Y 150JC, PARA FORMAR EL COMPUESTO DE FORMULA (I), EN LA QUE A Y B REPRESENTAN HIDROGENO O JUNTOS REPRESENTAN UN ENLACE, Y Y Z SON HIDROGENO O FORMAN UN ENLACE ENTRE AMBOS ATOMOS DE CARBONO, Y N VALE 0-2. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIHIPERCOLESTEROLEMICOS Y ANTIARTERIOESCLEROTICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60050544A JPH0629218B2 (ja) | 1985-03-15 | 1985-03-15 | ポリプレニル系化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8802064A1 true ES8802064A1 (es) | 1988-03-16 |
| ES557245A0 ES557245A0 (es) | 1988-03-16 |
Family
ID=12861949
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES552948A Expired ES8800124A1 (es) | 1985-03-15 | 1986-03-12 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos. |
| ES557244A Expired ES8802063A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
| ES557247A Expired ES8708239A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
| ES557242A Expired ES8801682A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
| ES557245A Expired ES8802064A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
| ES557243A Expired ES8708240A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
| ES557246A Expired ES8708241A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES552948A Expired ES8800124A1 (es) | 1985-03-15 | 1986-03-12 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos. |
| ES557244A Expired ES8802063A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
| ES557247A Expired ES8708239A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
| ES557242A Expired ES8801682A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES557243A Expired ES8708240A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
| ES557246A Expired ES8708241A1 (es) | 1985-03-15 | 1986-12-04 | Un procedimiento para la preparacion de nuevos compuestos poliprenilicos |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4788330A (es) |
| EP (1) | EP0194693B1 (es) |
| JP (1) | JPH0629218B2 (es) |
| KR (1) | KR920000877B1 (es) |
| AT (1) | ATE44950T1 (es) |
| AU (1) | AU596577B2 (es) |
| CA (1) | CA1264331A (es) |
| DE (1) | DE3664631D1 (es) |
| DK (1) | DK168432B1 (es) |
| ES (7) | ES8800124A1 (es) |
| FI (1) | FI91392C (es) |
| GR (1) | GR860568B (es) |
| HU (1) | HU197294B (es) |
| IE (1) | IE58413B1 (es) |
| NZ (1) | NZ215480A (es) |
| PH (1) | PH22339A (es) |
| PT (1) | PT82202B (es) |
| ZA (1) | ZA861645B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4714078A (en) * | 1984-12-03 | 1987-12-22 | Paluch Bernard R | Insert for heated humidifier used in respiratory therapy |
| US4823787A (en) * | 1987-07-09 | 1989-04-25 | Carmeli Adahan | Portable ventilator apparatus |
| US4883821A (en) * | 1988-04-13 | 1989-11-28 | Eisai Co., Ltd. | Agent for treating hyperuricemia |
| US20050250671A1 (en) * | 2000-04-24 | 2005-11-10 | Yoshihiro Shidoji | Activators of peroxisome proliferator-activated receptor |
| ES2470369T3 (es) * | 2002-05-17 | 2014-06-23 | Kowa Company, Ltd. | Inhibidores de la expresión de TGF-a |
| ES2448830T3 (es) * | 2002-08-20 | 2014-03-17 | Kowa Company, Ltd. | Preparación de cápsula blanda |
| US20080021105A1 (en) * | 2004-02-25 | 2008-01-24 | The University Of Tokyo | Medicine Capable of Inhibiting Activation of Transcription Factor Klf5 |
| FR2882359A1 (fr) * | 2005-02-24 | 2006-08-25 | Negma Lerads Soc Par Actions S | Derives activateurs de ppar, procede de preparation et application en therapeutique |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3046305A (en) * | 1959-09-24 | 1962-07-24 | Pure Oil Co | Process for the production of paralkyl-phenol and para-alkyl-benzoic acid |
| US3385887A (en) * | 1961-02-02 | 1968-05-28 | Boots Pure Drug Co Ltd | 4-isobutylphenylacetic acid |
| US3764621A (en) | 1967-04-20 | 1973-10-09 | Du Pont | Certain substituted methylbenzoic acids and substituted methycyclohexane carboxylic acids |
| FR2268791A1 (en) * | 1974-04-25 | 1975-11-21 | Nobel Hoechst Chimie | Para-alkyl benzoic acid alkanolamine condensate - useful as water-soluble or dispersable corrosion inhibitors for ferrous metals |
| JPS58225039A (ja) * | 1982-06-22 | 1983-12-27 | Eisai Co Ltd | ポリプレニル系化合物 |
| JPS59101448A (ja) * | 1982-11-30 | 1984-06-12 | Eisai Co Ltd | ポリプレニルカルボン酸アミドおよびその製造方法ならびにそれを含有する医薬 |
-
1985
- 1985-03-15 JP JP60050544A patent/JPH0629218B2/ja not_active Expired - Lifetime
-
1986
- 1986-02-25 FI FI860816A patent/FI91392C/fi not_active IP Right Cessation
- 1986-02-28 GR GR860568A patent/GR860568B/el unknown
- 1986-03-04 IE IE56886A patent/IE58413B1/en not_active IP Right Cessation
- 1986-03-05 ZA ZA861645A patent/ZA861645B/xx unknown
- 1986-03-05 PH PH33484A patent/PH22339A/en unknown
- 1986-03-07 KR KR1019860001627A patent/KR920000877B1/ko not_active IP Right Cessation
- 1986-03-07 US US03/837,472 patent/US4788330A/en not_active Expired - Fee Related
- 1986-03-11 AU AU54487/86A patent/AU596577B2/en not_active Ceased
- 1986-03-12 ES ES552948A patent/ES8800124A1/es not_active Expired
- 1986-03-13 DK DK116386A patent/DK168432B1/da not_active IP Right Cessation
- 1986-03-14 AT AT86103426T patent/ATE44950T1/de not_active IP Right Cessation
- 1986-03-14 NZ NZ215480A patent/NZ215480A/xx unknown
- 1986-03-14 HU HU861074A patent/HU197294B/hu not_active IP Right Cessation
- 1986-03-14 EP EP86103426A patent/EP0194693B1/en not_active Expired
- 1986-03-14 CA CA000504216A patent/CA1264331A/en not_active Expired - Fee Related
- 1986-03-14 DE DE8686103426T patent/DE3664631D1/de not_active Expired
- 1986-03-14 PT PT82202A patent/PT82202B/pt not_active IP Right Cessation
- 1986-12-04 ES ES557244A patent/ES8802063A1/es not_active Expired
- 1986-12-04 ES ES557247A patent/ES8708239A1/es not_active Expired
- 1986-12-04 ES ES557242A patent/ES8801682A1/es not_active Expired
- 1986-12-04 ES ES557245A patent/ES8802064A1/es not_active Expired
- 1986-12-04 ES ES557243A patent/ES8708240A1/es not_active Expired
- 1986-12-04 ES ES557246A patent/ES8708241A1/es not_active Expired
-
1988
- 1988-04-01 US US07/176,637 patent/US4883916A/en not_active Expired - Fee Related
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