ES8704872A1 - Un procedimiento para preparar aril-hidroxamatos - Google Patents

Un procedimiento para preparar aril-hidroxamatos

Info

Publication number
ES8704872A1
ES8704872A1 ES551514A ES551514A ES8704872A1 ES 8704872 A1 ES8704872 A1 ES 8704872A1 ES 551514 A ES551514 A ES 551514A ES 551514 A ES551514 A ES 551514A ES 8704872 A1 ES8704872 A1 ES 8704872A1
Authority
ES
Spain
Prior art keywords
aryl
alkyl
alkenyl
alkoxy
arylhydroxamates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551514A
Other languages
English (en)
Other versions
ES551514A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of ES8704872A1 publication Critical patent/ES8704872A1/es
Publication of ES551514A0 publication Critical patent/ES551514A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/04—Monocyclic monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C07C65/26—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/28—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups having unsaturation outside the aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ARILHIDROXAMATOS, DE FORMULA (I), Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN HIDROXIDO DE METAL ALCALINO PARA FORMAR UN COMPUESTO DE FORMULA (I), EN LA QUE R1 ES -(CH2)NCOOH, DONDE N VALE 1 A 4, Y R2 Y R3 PUEDEN SER VARIOS TIPOS DE RADICALES. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE 50JC Y 110JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIALERGICOS Y PARA EL TRATAMIENTO DEL ASMA BRONQUIAL.
ES551514A 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos Expired ES8704872A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61125184A 1984-05-17 1984-05-17
US06/719,935 US4607053A (en) 1984-05-17 1985-04-04 Arylhydroxamates useful as antiallergy agents

Publications (2)

Publication Number Publication Date
ES8704872A1 true ES8704872A1 (es) 1987-04-16
ES551514A0 ES551514A0 (es) 1987-04-16

Family

ID=27086475

Family Applications (7)

Application Number Title Priority Date Filing Date
ES543192A Expired ES8609201A1 (es) 1984-05-17 1985-05-16 Un procedimiento para preparar aril-hidroxamatos
ES551515A Expired ES8800129A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos
ES551517A Expired ES8706604A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos
ES551518A Expired ES8706605A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos
ES551514A Expired ES8704872A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos
ES551516A Expired ES8802378A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos
ES551519A Expired ES8706606A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES543192A Expired ES8609201A1 (es) 1984-05-17 1985-05-16 Un procedimiento para preparar aril-hidroxamatos
ES551515A Expired ES8800129A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos
ES551517A Expired ES8706604A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos
ES551518A Expired ES8706605A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES551516A Expired ES8802378A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos
ES551519A Expired ES8706606A1 (es) 1984-05-17 1986-01-31 Un procedimiento para preparar aril-hidroxamatos

Country Status (13)

Country Link
US (1) US4607053A (es)
EP (1) EP0161939B1 (es)
KR (1) KR910000855B1 (es)
AU (1) AU586973B2 (es)
DE (1) DE3587460T2 (es)
DK (1) DK217385A (es)
ES (7) ES8609201A1 (es)
FI (1) FI851970L (es)
GR (1) GR851203B (es)
HU (1) HU200594B (es)
IL (1) IL75223A (es)
NZ (1) NZ212099A (es)
PH (1) PH21267A (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE80611T1 (de) * 1985-03-16 1992-10-15 Wellcome Found Aryl-derivate.
IE59397B1 (en) * 1985-03-16 1994-02-23 Wellcome Found New aryl derivatives
GB8531839D0 (en) * 1985-12-30 1986-02-05 Wellcome Found Aryl derivatives
US5036157A (en) * 1986-03-11 1991-07-30 Burroughs Wellcome Co. Aryl derivatives
US4761403A (en) * 1986-04-09 1988-08-02 Abbott Laboratories Lipoxygenase inhibiting compounds
GB8609282D0 (en) * 1986-04-16 1986-05-21 Roussel Lab Ltd Chemical compounds
US4906667A (en) * 1986-07-30 1990-03-06 E. R. Squibb & Sons, Inc. Phenyl hydroxamic acids including a hetero-containing substituent
GB8619593D0 (en) * 1986-08-12 1986-09-24 Roussel Lab Ltd Chemical compounds
US4769461A (en) * 1986-09-16 1988-09-06 American Home Products Corporation Quinolinyl benzene hydroxamic acids as anti-inflammatory/antiallergic agents
US4681894A (en) * 1986-09-26 1987-07-21 Ortho Pharmaceutical Corporation Hydroxamic acids and esters
US4731382A (en) * 1986-12-29 1988-03-15 Bristol-Myers Company Lipoxygenase inhibitory phenylalkanohydroxamic acids
US4873259A (en) * 1987-06-10 1989-10-10 Abbott Laboratories Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds
US4822809A (en) * 1987-11-13 1989-04-18 Abbott Laboratories Benzazole lipoxygenase inhibiting compounds
GB2212153B (en) * 1987-11-16 1992-01-15 Squibb & Sons Inc Phenyl hydroxamic acids
WO1990012008A1 (en) * 1989-03-30 1990-10-18 Abbott Laboratories Urea based lipoxygenase inhibiting compounds
US5028629A (en) * 1990-03-28 1991-07-02 Eli Lilly And Company 5-Lipoxygenase inhibitors
EP0912549A4 (en) * 1996-06-20 2002-01-02 Univ Texas CONNECTIONS AND METHOD FOR PROVIDING ACTIVE PREPARATIONS AND THE USE THEREOF
US7842727B2 (en) * 2001-03-27 2010-11-30 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US6495719B2 (en) 2001-03-27 2002-12-17 Circagen Pharmaceutical Histone deacetylase inhibitors
US8026280B2 (en) 2001-03-27 2011-09-27 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7312247B2 (en) 2001-03-27 2007-12-25 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
DE10262084B4 (de) 2002-05-17 2009-12-24 Dr. Franz Köhler Chemie GmbH Protektive Lösung zur Verhinderung von Ischämieschäden
EP1511477A4 (en) * 2002-05-22 2008-04-09 Errant Gene Therapeutics Llc HISTONE DEACETYLASE INHIBITORS BASED ON ALPHA-KETO-EPOXYDE COMPOUNDS
AU2003291097A1 (en) * 2002-11-20 2004-06-15 Errant Gene Therapeutics, Llc Treatment of lung cells with histone deacetylase inhibitors
CN100554236C (zh) * 2004-04-01 2009-10-28 住友化学株式会社 制备羧酸化合物的方法
US20060160902A1 (en) * 2004-11-08 2006-07-20 Wiech Norbert L Histone deacetylase inhibitors
CN108697091B (zh) 2016-01-25 2021-07-23 美国陶氏益农公司 具有杀虫效用的分子，以及与其相关的中间体、组合物和方法
TWI780112B (zh) * 2017-03-31 2022-10-11 美商科迪華農業科技有限責任公司 具有殺蟲效用之分子，及其相關之中間物、組成物暨方法
CN114524753B (zh) * 2022-02-24 2024-03-26 安徽大学 一种多取代异羟肟酸衍生物的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2279973A (en) * 1940-05-08 1942-04-14 Du Pont Stabilization of organic substances
US2279560A (en) * 1940-05-08 1942-04-14 Du Pont Viscous hydrocarbon oil
CH220744A (de) * 1941-05-09 1942-04-30 Chem Ind Basel Verfahren zur Herstellung eines neuen Acetylderivats der technischen Stearinhydroxamsäure.
US3560519A (en) * 1969-03-28 1971-02-02 Sinclair Research Inc Aromatic mono(nitrile carbonates)
US3900514A (en) * 1971-06-03 1975-08-19 Kerr Mc Gee Chem Corp N-cycloalkyl hydroxamic acids
US3978208A (en) * 1974-01-07 1976-08-31 Eisai Co., Ltd. Deodorizing compositions
US4208205A (en) * 1977-10-03 1980-06-17 E. I. Du Pont De Nemours And Company Herbicidal benzamides
EP0103895A3 (en) * 1982-09-22 1985-07-03 Meiji Seika Kabushiki Kaisha Novel hydroxylamine derivatives, production and use thereof
NL8400852A (nl) * 1983-03-31 1984-10-16 Sandoz Ag Nieuwe anilinen en hun gebruik.
US4528392A (en) * 1984-04-18 1985-07-09 American Home Products Corporation Aromatic compounds as antiallergic agents
US4792560A (en) * 1985-04-03 1988-12-20 Rorer Pharmaceutical Corporation Quinoline hydroxamates and their use as modulators of arachidonic acid metabolic pathways

Also Published As

Publication number Publication date
GR851203B (es) 1985-11-25
EP0161939B1 (en) 1993-07-21
ES8609201A1 (es) 1986-09-01
HUT37742A (en) 1986-02-28
NZ212099A (en) 1989-08-29
IL75223A (en) 1988-05-31
AU4254685A (en) 1985-11-21
DK217385A (da) 1985-11-18
DK217385D0 (da) 1985-05-15
ES551519A0 (es) 1987-07-01
ES8800129A1 (es) 1987-10-16
ES543192A0 (es) 1986-09-01
HU200594B (en) 1990-07-28
ES8802378A1 (es) 1988-05-16
EP0161939A2 (en) 1985-11-21
PH21267A (en) 1987-09-28
AU586973B2 (en) 1989-08-03
IL75223A0 (en) 1985-09-29
ES551515A0 (es) 1987-10-16
ES551516A0 (es) 1988-05-16
KR910000855B1 (ko) 1991-02-11
DE3587460D1 (en) 1993-08-26
ES8706604A1 (es) 1987-07-01
ES551514A0 (es) 1987-04-16
ES8706605A1 (es) 1987-07-01
FI851970A0 (fi) 1985-05-17
EP0161939A3 (en) 1986-10-08
ES551517A0 (es) 1987-07-01
FI851970L (fi) 1985-11-18
KR850008660A (ko) 1985-12-21
DE3587460T2 (de) 1994-02-17
ES551518A0 (es) 1987-07-01
ES8706606A1 (es) 1987-07-01
US4607053A (en) 1986-08-19

Similar Documents

Publication Publication Date Title
ES8800129A1 (es) Un procedimiento para preparar aril-hidroxamatos
IE860873L (en) Hydroxamates
HK1020672A1 (en) Pharmaceutical compositions containing sulphamate derivatives as steroid sulphatase inhibitors
AU564842B2 (en) Pyranyl (or cyclohexyl) methane sulfamates and their use as anticonvulsants
GB8411731D0 (en) Oral compositions
HK1020728A1 (en) Improved process for the synthesis of protected esters of (s)-3,4-dihydroxybutyric acid
UA37191C2 (uk) Водна структурована композиція поверхнево-активної речовини
TW260673B (es)
ES8405364A1 (es) Metodo de preparar amidoaminoacidos n-substituidos.
ES8702143A1 (es) Un procedimiento para preparar derivados de piperazina con actividad psicotropica
ATE72448T1 (de) 2-alkynyladenosine als aktive bestandteile enthaltende antihypertensive mittel.
ATE28874T1 (de) 3,6-disubstituierte triazolo(3,4a>phthalazinderivate.
AU670121B2 (en) Antiretroviral acyl compounds
ES8206457A1 (es) Un procedimiento para la preparacion de compuestos n-acil-n- (cicloalquil) aminoacidos.
CA1264753C (en) 2-PYRIDYLCARBOXAMIDES
ES8702379A1 (es) Un procedimiento para la produccion de 1h-tetrazol-5-carboxamidas-n-sustituidas.
GR851683B (es)
ES8601182A1 (es) Procedimiento para la obtencion de tiolan-2,4-dion-3-carboxamidas
ES8705379A1 (es) Procedimiento para la obtencion de derivados de benzaldoxim-carbamato
ES8604846A1 (es) Procedimiento de preparar eteres 4-alquilfenil-2-alcoxieti- licos
ES8403434A1 (es) Procedimiento para preparar un derivado fluorado de alquileno diamina.
MY108187A (en) Stabilized pharmaceutical compositions comprising an hmg-coa reductase inhibitor compound
UA10967C2 (uk) 4,5-диметил-2-2-h-пропілтіо-2-w-h-перфторбутил-3h, 6h-тіаіh та спосіб його одержаhhя

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201