ES8704735A1 - Un procedimiento para la obtencion de un anticuerpo monoclo-nal - Google Patents

Un procedimiento para la obtencion de un anticuerpo monoclo-nal

Info

Publication number
ES8704735A1
ES8704735A1 ES548421A ES548421A ES8704735A1 ES 8704735 A1 ES8704735 A1 ES 8704735A1 ES 548421 A ES548421 A ES 548421A ES 548421 A ES548421 A ES 548421A ES 8704735 A1 ES8704735 A1 ES 8704735A1
Authority
ES
Spain
Prior art keywords
small cell
cell lung
residues
antigens
human non
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548421A
Other languages
English (en)
Other versions
ES548421A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncogen LP
Original Assignee
Oncogen LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen LP filed Critical Oncogen LP
Publication of ES8704735A1 publication Critical patent/ES8704735A1/es
Publication of ES548421A0 publication Critical patent/ES548421A0/es
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/863—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgM
    • Y10S530/864—Monoclonal
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/866—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody fragment, e.g. fab', fab, fv, fc, heavy chain or light chain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN ANTICUERPO MONOCLONAL. CONSISTE EN LAS OPERACIONES DE: A) FUSIONAR (I) UNA CELULA PRODUCTORA DE ANTICUERPOS, DERIVADA DEL BAZO DE UN ANIMAL INMUNIZADO CON EFUSIONES PLEURALES, CELULAS CULTIVADAS O TEJIDO PULMONAR DE UN PACIENTE CON CARCINOMA DE PULMON DE CELULAS NO PEQUEÑAS, CON (II) UNA MIELOMA, PARA OBTENER UN HIBRIDOMA; B) PROPAGAR EL HIBRIDOMA OBTENIDO EN LA OPERACION A); Y C) RECUPERAR LOS ANTICUERPOS MONOCLONALES PRODUCIDOS POR EL HIBRIDOMA; DONDE EL HIBRIDOMA SE PROPAGA IN VIVO INYECTANDO UN RATON BALB/C CEBADO CON PRISTANO Y HACIENDO CRECER UN TUMOS ASCITICO. TIENE APLICACIONES FARMACEUTICAS PARA EL TRATAMIENTO DE CELULAS CANCERIGENAS.
ES548421A 1984-11-02 1985-10-31 Un procedimiento para la obtencion de un anticuerpo monoclo-nal Expired ES8704735A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66752184A 1984-11-02 1984-11-02
US78517785A 1985-10-07 1985-10-07

Publications (2)

Publication Number Publication Date
ES8704735A1 true ES8704735A1 (es) 1987-04-16
ES548421A0 ES548421A0 (es) 1987-04-16

Family

ID=27099700

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548421A Expired ES8704735A1 (es) 1984-11-02 1985-10-31 Un procedimiento para la obtencion de un anticuerpo monoclo-nal

Country Status (21)

Country Link
EP (2) EP0207090B1 (es)
JP (3) JPH0675514B2 (es)
KR (1) KR910000903B1 (es)
AT (1) ATE117089T1 (es)
AU (1) AU599578B2 (es)
DE (1) DE3587976T2 (es)
DK (1) DK170619B1 (es)
ES (1) ES8704735A1 (es)
FI (1) FI85814C (es)
GB (1) GB2182949B (es)
GR (1) GR852622B (es)
HU (1) HU208546B (es)
IE (1) IE58590B1 (es)
IL (1) IL76877A (es)
NO (1) NO862690D0 (es)
NZ (1) NZ214055A (es)
OA (1) OA08354A (es)
PH (1) PH24961A (es)
PT (1) PT81418B (es)
WO (1) WO1986002735A1 (es)
YU (1) YU46386B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708930A (en) * 1984-11-09 1987-11-24 Coulter Corporation Monoclonal antibody to a human carcinoma tumor associated antigen
US4906562A (en) * 1984-12-21 1990-03-06 Oncogen Monocolonal antibodies and antigen for human non-small cell lung carcinomas
JPS61258173A (ja) * 1985-05-10 1986-11-15 Akira Taniuchi モノクロ−ナル抗体およびその製法ならびに用途
AU601680B2 (en) * 1985-05-28 1990-09-20 Joseph P. Brown Monoclonal antibodies for human non-small cell lung carcinomas
US5185432A (en) * 1986-02-26 1993-02-09 Oncogen Monoclonal antibodies and antigen for human non-small cell lung carcinoma and other certain human carcinomas
JPS6319561A (ja) * 1986-07-11 1988-01-27 Kyowa Hakko Kogyo Co Ltd 抗ヒト肺癌単クロ−ン性抗体
US6004761A (en) * 1986-11-19 1999-12-21 Sanofi Method for detecting cancer using monoclonal antibodies to new mucin epitopes
NZ222509A (en) * 1986-11-19 1993-03-26 Oncogen Hybridoma cell line producing antibodies binding to tumour-associated mucin antigen
CA1340221C (en) * 1988-01-29 1998-12-15 Thomas Frank Bumol Vectors, compounds and method for expression of a human adenocarcinoma antigen
AU632469B2 (en) * 1988-04-04 1993-01-07 Johns Hopkins University, The A method for early detection of lung cancer
US5171665A (en) * 1989-04-17 1992-12-15 Oncogen Monoclonal antibody to novel antigen associated with human tumors
IT1254309B (it) * 1992-02-17 1995-09-14 Uni Degli Studi G D Annunzio C Sequenze genetiche per l'antigene 90k associato a tumori.
IT1264490B (it) * 1992-02-17 1996-09-24 Uni Degli Studi G D Annunzio C Antigene 90k associato a tumori.
JPH0727604U (ja) * 1993-06-18 1995-05-23 修司 坂本 磁気治療具
EP0695760A1 (en) * 1994-08-05 1996-02-07 F. Hoffmann-La Roche Ag Novel tumor marker for lung cancer
DE202012001863U1 (de) 2012-02-22 2012-03-19 Haldex Brake Products Ab Scheibenbremse und Sensoreinrichtung hierfür

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies
US4906562A (en) * 1984-12-21 1990-03-06 Oncogen Monocolonal antibodies and antigen for human non-small cell lung carcinomas
JPS61258173A (ja) * 1985-05-10 1986-11-15 Akira Taniuchi モノクロ−ナル抗体およびその製法ならびに用途
AU601680B2 (en) * 1985-05-28 1990-09-20 Joseph P. Brown Monoclonal antibodies for human non-small cell lung carcinomas

Also Published As

Publication number Publication date
PT81418A (en) 1985-11-01
FI85814C (fi) 1992-06-10
HU208546B (en) 1993-11-29
JP2567564B2 (ja) 1996-12-25
DK170619B1 (da) 1995-11-13
GB2182949B (en) 1989-05-24
IE852681L (en) 1986-05-02
FI862821A0 (fi) 1986-07-02
GR852622B (es) 1986-03-04
JPH0675514B2 (ja) 1994-09-28
EP0566066A1 (en) 1993-10-20
JPS62501955A (ja) 1987-08-06
GB2182949A (en) 1987-05-28
DE3587976T2 (de) 1995-05-18
IL76877A (en) 1991-11-21
OA08354A (en) 1988-02-29
ATE117089T1 (de) 1995-01-15
GB8616219D0 (en) 1986-08-13
PT81418B (pt) 1987-11-11
NO862690D0 (no) 1986-07-02
JPH0733400B2 (ja) 1995-04-12
WO1986002735A1 (en) 1986-05-09
IE58590B1 (en) 1993-10-20
NZ214055A (en) 1991-06-25
YU172185A (en) 1989-08-31
DK314586A (da) 1986-09-01
KR910000903B1 (ko) 1991-02-12
DE3587976D1 (de) 1995-02-23
ES548421A0 (es) 1987-04-16
YU46386B (sh) 1993-10-20
DK314586D0 (da) 1986-07-02
IL76877A0 (en) 1986-02-28
FI85814B (fi) 1992-02-28
JPH06340699A (ja) 1994-12-13
EP0207090B1 (en) 1995-01-11
AU599578B2 (en) 1990-07-26
PH24961A (en) 1990-12-26
HUT43188A (en) 1987-09-28
JPH06296497A (ja) 1994-10-25
FI862821A (fi) 1986-07-02
KR880700268A (ko) 1988-02-22
EP0207090A4 (en) 1988-04-26
AU5069185A (en) 1986-05-15
EP0207090A1 (en) 1987-01-07

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20011110