ES8703447A1 - Procedimiento para la preparacion de una (2-3-trans)-lactona - Google Patents

Procedimiento para la preparacion de una (2-3-trans)-lactona

Info

Publication number
ES8703447A1
ES8703447A1 ES550952A ES550952A ES8703447A1 ES 8703447 A1 ES8703447 A1 ES 8703447A1 ES 550952 A ES550952 A ES 550952A ES 550952 A ES550952 A ES 550952A ES 8703447 A1 ES8703447 A1 ES 8703447A1
Authority
ES
Spain
Prior art keywords
formula
making
erythro
polymethylene
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550952A
Other languages
English (en)
Other versions
ES550952A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of ES550952A0 publication Critical patent/ES550952A0/es
Publication of ES8703447A1 publication Critical patent/ES8703447A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Pyrane Compounds (AREA)
  • Television Signal Processing For Recording (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 2,3-TRANS LACTONAS, DE FORMULA (I), EN FORMA RACEMICA U OPTICAMENTE ACTIVA. CONSISTE EN LA REDUCCION SELECTIVA DE UN ACIDO TRANS-FENILPARACONICO, DE FORMULA (II) O UN DERIVADO ADECUADO DEL MISMO, PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LA QUE EL ANILLO BENCENICO B PUEDE TENER UNO O DOS SUSTITUYENTES. LA REDUCCION SE LLEVA A CABO CON UN DIBORANO O UN BOROHIDRURO DE METAL ALCALINO, EN PRESENCIA DE UN ACIDO DE LEWIS TAL COMO CLORURO DE ESTAÑO (IV). ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTAGONISTAS DE LAS ACCIONES DEL TROMBOXANO A2.
ES550952A 1983-11-11 1986-01-16 Procedimiento para la preparacion de una (2-3-trans)-lactona Expired ES8703447A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838330120A GB8330120D0 (en) 1983-11-11 1983-11-11 Chemical process

Publications (2)

Publication Number Publication Date
ES550952A0 ES550952A0 (es) 1987-02-16
ES8703447A1 true ES8703447A1 (es) 1987-02-16

Family

ID=10551607

Family Applications (2)

Application Number Title Priority Date Filing Date
ES537543A Expired ES8607897A1 (es) 1983-11-11 1984-11-08 Procedimiento para la preparacion de un eritro-diol
ES550952A Expired ES8703447A1 (es) 1983-11-11 1986-01-16 Procedimiento para la preparacion de una (2-3-trans)-lactona

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES537543A Expired ES8607897A1 (es) 1983-11-11 1984-11-08 Procedimiento para la preparacion de un eritro-diol

Country Status (24)

Country Link
US (2) US4723037A (es)
EP (3) EP0304138B1 (es)
JP (1) JPS60123444A (es)
KR (1) KR920010180B1 (es)
AT (3) ATE67195T1 (es)
AU (1) AU587962B2 (es)
CA (1) CA1283926C (es)
CS (1) CS251777B2 (es)
DD (1) DD231351A5 (es)
DE (3) DE3485065D1 (es)
DK (1) DK535584A (es)
ES (2) ES8607897A1 (es)
FI (1) FI88029C (es)
GB (1) GB8330120D0 (es)
GR (1) GR80833B (es)
HU (2) HU196595B (es)
IE (1) IE57771B1 (es)
IL (1) IL73373A (es)
NO (1) NO158671C (es)
NZ (1) NZ210160A (es)
PL (1) PL144623B1 (es)
PT (1) PT79477B (es)
SU (1) SU1480760A3 (es)
ZA (1) ZA848472B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8511891D0 (en) * 1985-05-10 1985-06-19 Ici Plc Alkenoic acids
GB8511890D0 (en) * 1985-05-10 1985-06-19 Ici Plc Benzene derivatives
DK212786A (da) * 1985-05-10 1986-11-11 Ici Plc 1,3-dioxanethere
GB8511894D0 (en) 1985-05-10 1985-06-19 Ici Plc Phenol derivatives
ES8802508A1 (es) * 1985-05-10 1988-07-16 Ici Plc Procedimiento para preparar derivados alquenicos.
GB8611174D0 (en) * 1986-05-08 1986-06-18 Ici Plc Amide derivatives
GB8626297D0 (en) * 1986-11-04 1986-12-03 Ici Plc Pharmaceutical compositions
GB8626296D0 (en) * 1986-11-04 1986-12-03 Ici Plc Therapeutic agents
GB8709794D0 (en) * 1987-04-24 1987-05-28 Ici Plc Heterocyclic acids
US5248780A (en) * 1988-02-16 1993-09-28 Imperial Chemical Industries, Plc Pyridyl substituted alkenoic acid derivatives
GB8901201D0 (en) * 1988-02-16 1989-03-15 Ici Plc Pyridine derivatives
GB8814340D0 (en) * 1988-06-16 1988-07-20 Ici Plc Process
GB9021571D0 (en) * 1990-10-04 1990-11-21 Ici Plc Heterocyclic acids
WO2002085833A1 (fr) * 2001-04-18 2002-10-31 Kuraray Co., Ltd. Procede de preparation d'acide 2-benzyl-succinique a activite optique et de monamides de l'acide 2-benzyl-succinique a activite optique
WO2007138485A2 (en) * 2006-01-18 2007-12-06 Evolva Sa Ppar modulators
MX2009007670A (es) * 2007-01-18 2011-11-18 Evolva Sa 1,3-dioxanos sustituidos utiles como moduladores de paar.
EP2124551A4 (en) * 2007-01-18 2010-07-28 Evolva Sa SUBSTITUTED 1, 3-DIOXANES AND THEIR USE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids

Also Published As

Publication number Publication date
GB8330120D0 (en) 1983-12-21
NZ210160A (en) 1988-08-30
GR80833B (en) 1985-01-03
KR920010180B1 (ko) 1992-11-19
EP0142323A3 (en) 1986-02-26
AU587962B2 (en) 1989-09-07
IE57771B1 (en) 1993-04-07
ES550952A0 (es) 1987-02-16
HUT36821A (en) 1985-10-28
NO158671B (no) 1988-07-11
DK535584D0 (da) 1984-11-09
HU196162B (en) 1988-10-28
EP0142323B1 (en) 1990-03-07
IE842718L (en) 1985-05-11
ES537543A0 (es) 1986-06-01
FI844394L (fi) 1985-05-12
HU196595B (en) 1988-12-28
KR850003533A (ko) 1985-06-20
US4900846A (en) 1990-02-13
PL144623B1 (en) 1988-06-30
US4723037A (en) 1988-02-02
DK535584A (da) 1985-05-12
PT79477B (en) 1987-01-13
CA1283926C (en) 1991-05-07
EP0304138B1 (en) 1992-03-04
CS850584A2 (en) 1986-12-18
ATE67195T1 (de) 1991-09-15
IL73373A0 (en) 1985-01-31
ZA848472B (en) 1985-08-28
DE3485065D1 (de) 1991-10-17
FI844394A0 (fi) 1984-11-08
DE3481513D1 (de) 1990-04-12
PL250365A1 (en) 1985-12-17
EP0304139B1 (en) 1991-09-11
EP0304138A1 (en) 1989-02-22
NO158671C (no) 1988-10-19
DD231351A5 (de) 1985-12-24
DE3485550D1 (de) 1992-04-09
AU3526684A (en) 1985-05-16
JPS60123444A (ja) 1985-07-02
PT79477A (en) 1984-12-01
CS251777B2 (en) 1987-08-13
EP0142323A2 (en) 1985-05-22
EP0304139A1 (en) 1989-02-22
FI88029B (fi) 1992-12-15
FI88029C (fi) 1993-03-25
IL73373A (en) 1989-09-10
ES8607897A1 (es) 1986-06-01
ATE50772T1 (de) 1990-03-15
NO844481L (no) 1985-05-13
ATE73134T1 (de) 1992-03-15
SU1480760A3 (ru) 1989-05-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401