ES8609354A1 - Un procedimiento para preparar un derivado de acido sialico - Google Patents

Un procedimiento para preparar un derivado de acido sialico

Info

Publication number
ES8609354A1
ES8609354A1 ES544630A ES544630A ES8609354A1 ES 8609354 A1 ES8609354 A1 ES 8609354A1 ES 544630 A ES544630 A ES 544630A ES 544630 A ES544630 A ES 544630A ES 8609354 A1 ES8609354 A1 ES 8609354A1
Authority
ES
Spain
Prior art keywords
derivatives
sialic acid
producing
same
galactose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES544630A
Other languages
English (en)
Other versions
ES544630A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KANTO ISHI PHARMA CO Ltd
RIKEN Institute of Physical and Chemical Research
Original Assignee
KANTO ISHI PHARMA CO Ltd
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59133882A external-priority patent/JPS6112697A/ja
Priority claimed from JP59133881A external-priority patent/JPS6112695A/ja
Application filed by KANTO ISHI PHARMA CO Ltd, RIKEN Institute of Physical and Chemical Research filed Critical KANTO ISHI PHARMA CO Ltd
Publication of ES544630A0 publication Critical patent/ES544630A0/es
Publication of ES8609354A1 publication Critical patent/ES8609354A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals
    • C07H7/027—Keto-aldonic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

SE PREPARAN DERIVADOS DE ACIDO SIALICO O GANGLIOSIDOS, DE FORMULA (I), HACIENDO REACCIONAR UN COMPUESTO DE LA FORMULA (II) CON UNA CERAMIDA DE FORMULA (III), EN PRESENCIA DE UN CATALIZADOR DE GLICOSIDACION (BF3-ETER/TAMICES MOLECULARES 4A) PARA DAR UN COMPUESTO DE LA FORMULA (IV), Y TRATANDO ESTE DE LA MANERA ACOSTUMBRADA PARA ELIMINAR ACETILO Y BENZOILO. LOS GANGLIOSIDOS INTERVIENEN EN LA RECEPCION, RECONOCIMIENTO Y RESPUESTA DE LA INFORMACION CELULAR, EN LA DIFERENCIACION Y PROPAGACION CELULAR, EN LA TRANSFORMACION DE CELULAS MALIGNAS, ETC.
ES544630A 1984-06-28 1985-06-27 Un procedimiento para preparar un derivado de acido sialico Expired ES8609354A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59133882A JPS6112697A (ja) 1984-06-28 1984-06-28 ガラクト−ス誘導体
JP59133881A JPS6112695A (ja) 1984-06-28 1984-06-28 シアル酸誘導体

Publications (2)

Publication Number Publication Date
ES544630A0 ES544630A0 (es) 1986-09-01
ES8609354A1 true ES8609354A1 (es) 1986-09-01

Family

ID=26468120

Family Applications (1)

Application Number Title Priority Date Filing Date
ES544630A Expired ES8609354A1 (es) 1984-06-28 1985-06-27 Un procedimiento para preparar un derivado de acido sialico

Country Status (7)

Country Link
US (1) US4968786A (es)
EP (1) EP0166442A3 (es)
KR (1) KR920002826B1 (es)
AU (1) AU582758B2 (es)
CA (1) CA1262129A1 (es)
ES (1) ES8609354A1 (es)
HU (1) HU196818B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ222192A (en) * 1986-10-20 1991-03-26 Kanto Ishi Pharma Co Ltd Glycolipid containing n-glycolylneuraminic acid, and preparation thereof
US5034516A (en) * 1987-08-04 1991-07-23 University Of Ottawa Synthetic antigens of sialic acid and derivatives thereof
US5192661A (en) * 1987-08-04 1993-03-09 University Of Ottawa Multicomponent kit containing an antibody to a synthetic antigen of sialic acid
US5344870A (en) * 1987-12-02 1994-09-06 Alberta Research Council Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
US5272138A (en) * 1988-02-12 1993-12-21 The Biomembrane Institute Naturally occurring gangliosides containing de-N-acetyl-sialic acid and their applications as modifiers of cell physiology
JPH0276892A (ja) * 1988-06-16 1990-03-16 Toshio Goto ３−フェニルチオシアル酸誘導体、その製造方法、シアル酸含有オリゴ糖誘導体およびその製造方法
JP2782069B2 (ja) * 1988-08-12 1998-07-30 和光純薬工業株式会社 ガングリオシド類の新規な製造法
JP2745059B2 (ja) * 1989-03-08 1998-04-28 メクト株式会社 Ｎ―アセチルノイラミン酸ナトリウム・三水和物
JPH03242553A (ja) * 1990-02-19 1991-10-29 Mect Corp エピシアロ複合糖質を含む製剤
US5264567A (en) * 1990-10-22 1993-11-23 Mect Corporation GM3 analogous compound
JPH04159290A (ja) * 1990-10-22 1992-06-02 Mect Corp Ｇｍ↓３類縁化合物及びその合成法
US5646123A (en) * 1991-06-10 1997-07-08 Alberta Research Council Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen
CA2692419C (en) * 2007-07-03 2017-12-05 Children's Hospital & Research Center At Oakland Inhibitors of polysialic acid de-n-acetylase and methods for using the same
JP5523313B2 (ja) * 2007-07-03 2014-06-18 チルドレンズ ホスピタル アンド リサーチ センター アット オークランド ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用
AU2008272792B2 (en) * 2007-07-03 2014-03-06 Children's Hospital & Research Center At Oakland Oligosialic acid derivatives, methods of manufacture, and immunological uses

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54130512A (en) * 1978-03-30 1979-10-09 Rikagaku Kenkyusho Preparation of selectively-benzylated sugar derivatives
FI67386C (fi) * 1979-06-21 1985-03-11 Hoffmann La Roche Foerfarande foer framstaellning av nya terapeutiskt anvaendbara sockerderivat
DE2942365A1 (de) * 1979-10-19 1981-05-14 Bayer Ag, 5090 Leverkusen 2-hydroxyalkyl-3,4,5-trihydroxy-(pi)-peridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4495346A (en) * 1981-03-30 1985-01-22 Wisconsin Alumni Research Foundation Method of preparing a disaccharide
US4521592A (en) * 1981-10-23 1985-06-04 Svenska Sockerfabriks Ab Compounds for therapeutic or diagnostic use, a process and intermediates for their preparation
DE3374317D1 (en) * 1982-11-26 1987-12-10 Nippon Kayaku Kk Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
US4514561A (en) * 1983-04-15 1985-04-30 Research Corporation Process for preparing α-L N-acetyl daunosaminide
US4521240A (en) * 1983-04-29 1985-06-04 Chevron Research Company 5-C-Alkyl-3-O-arylmethyl or substituted arylmethyl-1,2-O-alkylidene-α-
US4609478A (en) * 1984-02-21 1986-09-02 Olin Corporation Sulfonated alkyl glucosides and use thereof in oil recovery
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
SE8501613D0 (sv) * 1985-04-01 1985-04-01 Bio Carb Ab Foreningar for terapeutisk eller diagnostisk anvendning jemte forfarande for terapeutisk behandling

Also Published As

Publication number Publication date
ES544630A0 (es) 1986-09-01
HU196818B (en) 1989-01-30
CA1262129A1 (en) 1989-10-03
CA1269366C (es) 1990-05-22
AU4421285A (en) 1986-01-02
EP0166442A2 (en) 1986-01-02
AU582758B2 (en) 1989-04-13
HUT38653A (en) 1986-06-30
US4968786A (en) 1990-11-06
EP0166442A3 (en) 1987-10-21
KR920002826B1 (ko) 1992-04-04
KR860000312A (ko) 1986-01-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303