ES8607906A1 - Procedimiento para la obtencion de composiciones farmaceuti-cas conteniendo liposomas unilamilares - Google Patents

Procedimiento para la obtencion de composiciones farmaceuti-cas conteniendo liposomas unilamilares

Info

Publication number
ES8607906A1
ES8607906A1 ES540372A ES540372A ES8607906A1 ES 8607906 A1 ES8607906 A1 ES 8607906A1 ES 540372 A ES540372 A ES 540372A ES 540372 A ES540372 A ES 540372A ES 8607906 A1 ES8607906 A1 ES 8607906A1
Authority
ES
Spain
Prior art keywords
unilamellar liposomes
pharmaceutical compositions
compositions containing
preparing pharmaceutical
containing unilamellar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES540372A
Other languages
English (en)
Other versions
ES540372A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8607906A1 publication Critical patent/ES8607906A1/es
Publication of ES540372A0 publication Critical patent/ES540372A0/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

METODO DE PREPARACION DE COMPOSICIONES FARMACEUTICAS QUE CONTIENEN LIPOSIMAS UNILAMILARES, EN FORMA DE DISPERSIONES ACUOSAS, CONSTITUIDAS POR UN COMPUESTO AMFIPATICO CON AFECTO BIOLOGICO Y UN FOSFOLIPIDO O ANALOGO. CONSISTE EN MEZCLAR DE MODO HOMOGENEO UN COMPUESTO ANFIPATICO CON EFECTO BIOLOGICO Y UN FOSFOLIPIDO O ANALOGO, SEGUIDO DE LA DISPERSION DE ESTA MEZCLA EN FASE ACUOSA Y NEUTRALIZACION DE LA MISMA. LA MEZCLA HOMOGENEA SE PREPARA POR SECADO POR PULVERIZACION DE UNA DISOLUCION DE LOS COMPONENTES. LA DISPERSION SE LOGRA MEDIANTE AGITACION DE LA MEZCLA HOMOGENEA PREVIAMENTE PREPARADA. LA NEUTRALIZACION SE EFECTUA CON UNA DISOLUCION ACUOSA DILUIDA, FISIOLOGICAMENTE COMPATIBLE, DE UN ACIDO O UNA DISOLUCION TAMPON DE PH 7 A 8. ESTAS COMPOSICIONES TIENEN APLICACIONES FARMACOLOGICAS EN LAS QUE LOS LIPOSOMAS ACTUAN COMO PORTADORES DE ANTICUERPOS O ENZIMAS, HORMONAS VITAMINAS O GENES.
ES540372A 1984-02-15 1985-02-13 Procedimiento para la obtencion de composiciones farmaceuti-cas conteniendo liposomas unilamilares Expired ES8607906A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH73684 1984-02-15

Publications (2)

Publication Number Publication Date
ES8607906A1 true ES8607906A1 (es) 1986-06-01
ES540372A0 ES540372A0 (es) 1986-06-01

Family

ID=4194001

Family Applications (1)

Application Number Title Priority Date Filing Date
ES540372A Expired ES8607906A1 (es) 1984-02-15 1985-02-13 Procedimiento para la obtencion de composiciones farmaceuti-cas conteniendo liposomas unilamilares

Country Status (7)

Country Link
EP (1) EP0152379A3 (es)
JP (1) JPS60190710A (es)
AU (1) AU588798B2 (es)
CA (1) CA1246446A (es)
DK (1) DK68585A (es)
ES (1) ES8607906A1 (es)
ZA (1) ZA851111B (es)

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DE3623193A1 (de) * 1986-07-10 1988-01-14 Gruenenthal Gmbh Neue verbindungen, diese enthaltende arzneimittel und verfahren zu deren herstellung
EP0265388A1 (de) * 1986-10-24 1988-04-27 Ciba-Geigy Ag Pyrrol-Derivate, therapeutische Mittel, die sie enthalten und ihre Verwendung
CH673395A5 (es) * 1987-01-30 1990-03-15 Ciba Geigy Ag
AU614527B2 (en) * 1987-07-24 1991-09-05 Nexstar Pharmaceuticals, Inc. Opioid analgesic liposomal delivery-release system
JPH03501253A (ja) * 1987-09-22 1991-03-22 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア エイズ（ａｉｄｓ）治療を目的とするリポソームによるヌクレオシド類似物質
US5830498A (en) * 1987-10-16 1998-11-03 Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
JPH04505616A (ja) * 1989-05-15 1992-10-01 ザ　リポソーム　カンパニー，インコーポレイテッド プロトン勾配によるリポソームへの薬剤の蓄積
FR2648462B1 (fr) * 1989-06-15 1994-01-28 Oreal Procede pour ameliorer l'efficacite therapeutique de corticosteroides liposolubles et composition pour la mise en oeuvre de ce procede
IT1240354B (it) * 1990-03-30 1993-12-07 Poli Ind Chimica Spa Formulazioni liposomiali di farmaci antimicotici,antibatterici e/o antantiflogistici per applicazione locale e vaginale
AT393955B (de) * 1990-03-30 1992-01-10 Martin Dr Leixnering Einrichtung zur nachbehandlung frischer beugesehnenverletzungen
DE4018767A1 (de) * 1990-06-12 1991-12-19 Braun Melsungen Ag Wirkstofffreie liposomen zur behandlung von atherosklerose
DE4037554A1 (de) * 1990-11-26 1992-05-27 Roemmers Sa Arzneimittel zur topischen anwendung
US5444076A (en) * 1990-11-26 1995-08-22 Roemmers S.A.I.C.F. Pharmaceutical preparation for topical application
DE69107309T2 (de) * 1990-12-03 1995-06-08 Vestar Inc Verhütung der synovialischen adhäsion.
GB9126209D0 (en) * 1991-12-10 1992-02-12 Orion Yhtymae Oy Drug formulations for parenteral use
GB9212450D0 (en) * 1992-06-11 1992-07-22 Indena Spa New derivatives of non-steroidal anti-inflammatory,analgesic and/or antipyretic substances,their use and pharmaceutical formulations containing them
NZ260408A (en) 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
WO1994028876A1 (en) * 1993-06-07 1994-12-22 Advanced Therapies, Inc. Liposome powders
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
KR100414810B1 (ko) * 1995-03-17 2004-04-29 시바 스페셜티 케미칼스 홀딩 인크. 리포좀형성uv흡수제
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US5731339A (en) * 1995-04-28 1998-03-24 Zonagen, Inc. Methods and formulations for modulating the human sexual response
GB9605915D0 (en) * 1996-03-21 1996-05-22 Univ Bruxelles Liposome encapsulated amphiphilic drug compositions
DE59712179D1 (de) * 1996-09-17 2005-03-03 Ciba Sc Holding Ag Verwendung liposomogener UV-Absorber zum Schutz des Haars
PT1135193E (pt) * 1998-12-04 2003-01-31 Max Delbrueck Centrum Agentes para o tratamento de tumores a base de lipossomas e compreendendo tamoxifeno
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EP1031346B1 (en) 1999-01-27 2002-05-02 Idea Ag Noninvasive vaccination through the skin
SI1031347T1 (en) 1999-01-27 2002-10-31 Idea Ag Transnasal transport/immunisation with highly adaptable carriers
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
WO2001001962A1 (en) 1999-07-05 2001-01-11 Idea Ag. A method for the improvement of transport across adaptable semi-permeable barriers
EP1689364A4 (en) * 2003-11-20 2008-10-29 Ym Biosciences Inc STABLE LIPOSOMAL COMPOSITIONS COMPRISING LIPOPHILIC AMINE CONTAINING PHARMACEUTICAL AGENTS
AT500143A1 (de) * 2004-04-22 2005-11-15 Sanochemia Pharmazeutika Ag Cholinesterase-inhibitoren in liposomen sowie deren herstellung und verwendung
AU2013206215C9 (en) * 2006-07-09 2018-03-08 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aspirin
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
CN103922946A (zh) * 2006-07-09 2014-07-16 于崇曦 带有正电荷的水溶性阿司匹林前药
AU2016219617B2 (en) * 2006-07-09 2018-05-17 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aspirin
WO2008007171A1 (en) * 2006-07-09 2008-01-17 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aspirin
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
PL2170826T3 (pl) 2007-06-04 2022-09-05 Techfields Inc Proleki nsaia o bardzo wysokim współczynniku przenikania przez skórę i błony oraz ich nowe zastosowania lecznicze
CA3213470A1 (en) 2008-12-04 2010-06-10 Chongxi Yu High penetration compositions and their applications
CA3189252A1 (en) 2012-05-16 2013-11-21 Techfields Pharma Co., Ltd. High penetration prodrug compositions and pharmaceutical composition thereof for treatment of pulmonary conditions
JP6289438B2 (ja) * 2015-12-03 2018-03-07 テックフィールズ バイオケム カンパニー リミテッド アスピリンの正荷電水溶性プロドラッグ
JP6588485B2 (ja) * 2017-02-21 2019-10-09 テックフィールズ バイオケム カンパニー リミテッド アスピリンの正荷電水溶性プロドラッグ
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
JP2018058899A (ja) * 2018-01-04 2018-04-12 テックフィールズ バイオケム カンパニー リミテッド アスピリンの正荷電水溶性プロドラッグ
EP3955918A1 (en) 2019-04-17 2022-02-23 COMPASS Pathfinder Limited Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
KR20230012501A (ko) 2020-05-19 2023-01-26 사이빈 아이알엘 리미티드 중수소화된 트립타민 유도체 및 사용 방법

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JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
JPS5782310A (en) * 1980-11-11 1982-05-22 Tanabe Seiyaku Co Ltd Production of liposome preparation
IL64397A0 (en) * 1981-01-07 1982-02-28 Weder Hans G Process for the preparation of liposomal medicaments
DE3374837D1 (en) * 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
EP0102324A3 (de) * 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
JPS607932A (ja) * 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソーム懸濁液およびその製法
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JPS60208910A (ja) * 1984-03-31 1985-10-21 Green Cross Corp:The 水難溶性薬物・リン脂質複合体の製造方法

Also Published As

Publication number Publication date
DK68585D0 (da) 1985-02-14
AU3875385A (en) 1985-08-22
ES540372A0 (es) 1986-06-01
CA1246446A (en) 1988-12-13
DK68585A (da) 1985-08-16
ZA851111B (en) 1985-09-25
EP0152379A3 (de) 1986-10-29
JPS60190710A (ja) 1985-09-28
AU588798B2 (en) 1989-09-28
EP0152379A2 (de) 1985-08-21

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