ES8607266A1 - Un procedimiento para preparar nuevos derivados de milbemicinas. - Google Patents

Un procedimiento para preparar nuevos derivados de milbemicinas.

Info

Publication number
ES8607266A1
ES8607266A1 ES537650A ES537650A ES8607266A1 ES 8607266 A1 ES8607266 A1 ES 8607266A1 ES 537650 A ES537650 A ES 537650A ES 537650 A ES537650 A ES 537650A ES 8607266 A1 ES8607266 A1 ES 8607266A1
Authority
ES
Spain
Prior art keywords
milbemycin
preparation
compositions containing
carbonate derivatives
carbonate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537650A
Other languages
English (en)
Other versions
ES537650A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES537650A0 publication Critical patent/ES537650A0/es
Publication of ES8607266A1 publication Critical patent/ES8607266A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A01N47/06—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing —O—CO—O— groups; Thio analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS DE MILBEMICINAS. CONSISTE EN HACER REACCIONAR MILBEMICINA A3, A4 O D CON UN HALO COMPUESTO DE FORMULA C.CO.ORY DONDE RY REPRESENTA R2 O Y, Y, CUANDO RY REPRESENTA Y, HACER REACCIONAR EL PRODUCTO DEL MISMO CON UN COMPUESTO DE FORMULA R7-H, DONDE R7 REPRESENTA UN GRUPO DE FORMULA -Q-R4K O UN GRUPO DE FORMULA -O.CO.R5, PARA OBTENER NUEVOS DERIVADOS DE MILBEMICINAS DE FORMULA (I) DONDE R1 REPRESENTA UN GRUPO METILO, ETILO O ISOPROPILO; Y R2 REPRESENTA UN GRUPO FORMADO CON UN ALCOHOL DE AZUCAR, AZUCAR O ACIDO ALDONICO OPCIONALMENTE PROTEGIDO MEDIANTE LA SEPARACION DEL GRUPO HIDROXI V-ALCOHOLICO DEL MISMO, O UN GRUPO DE FORMULA -A-R3. LA REACCION SE EFECTUA EN PRESENCIA DE UN DISOLVENTE, A TEMPERATURA ENTRE 0 Y 100JC Y EN UN INTERVALO DE TIEMPO DE 30 MINUTOS A 5 HORAS.
ES537650A 1983-11-14 1984-11-14 Un procedimiento para preparar nuevos derivados de milbemicinas. Expired ES8607266A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58213588A JPS60126289A (ja) 1983-11-14 1983-11-14 ミルベマイシン類の５−カ−ボネ−ト誘導体

Publications (2)

Publication Number Publication Date
ES537650A0 ES537650A0 (es) 1986-05-16
ES8607266A1 true ES8607266A1 (es) 1986-05-16

Family

ID=16641684

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537650A Expired ES8607266A1 (es) 1983-11-14 1984-11-14 Un procedimiento para preparar nuevos derivados de milbemicinas.

Country Status (12)

Country Link
US (1) US4760054A (es)
EP (1) EP0142969B1 (es)
JP (1) JPS60126289A (es)
KR (1) KR910006443B1 (es)
AU (1) AU573766B2 (es)
CA (1) CA1235693A (es)
DE (1) DE3478438D1 (es)
DK (1) DK164912C (es)
ES (1) ES8607266A1 (es)
IL (1) IL73508A (es)
NZ (1) NZ210210A (es)
ZA (1) ZA848826B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
EP0165900A3 (de) * 1984-06-08 1986-05-28 Ciba-Geigy Ag Neue Lactone, Verfahren zu ihrer Herstellung und ihre Verwendung in der Schädlingsbekämpfung
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
US4778809A (en) * 1985-08-23 1988-10-18 Ciba-Geigy Corporation 5-esters of milbemycins for controlling parasitic pests
JPH0678342B2 (ja) * 1986-01-07 1994-10-05 三共株式会社 新規マクロライド化合物
EP0237482A1 (de) * 1986-03-06 1987-09-16 Ciba-Geigy Ag C(29)-Carbonyloxi-milbemycin-Derivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen
NZ219467A (en) * 1986-03-07 1990-03-27 Ciba Geigy Ag 5-acyloxy 13b-alkyl milbemycins and parasiticidal compositions
PH24180A (en) * 1986-03-12 1990-03-22 Glaxo Group Ltd Macrolide compounds,pharmaceutical composition containing said compound and method of use thereof
IE62125B1 (en) * 1986-03-12 1994-12-14 American Cyanamid Co Macrolide compounds
EP0245209A1 (de) * 1986-05-07 1987-11-11 Ciba-Geigy Ag Milbemycin-Derivate, ihre Herstellung und ihre Verwendung zur Bekämpfung von Schädlingen
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
JP2549558B2 (ja) * 1989-04-13 1996-10-30 和夫 藤田 電動ステージ装置
JP2952265B2 (ja) * 1993-11-29 1999-09-20 井筒屋化学産業株式会社 松類の枯損防止用組成物及び防止方法
DE19646720C2 (de) * 1996-11-12 1999-02-18 Ina Matallana Kielmann Verfahren zum Vergleich von Peak-Darstellungen, insbesondere von Westernblot- oder Dot Blot-Streifen
DE102010064245A1 (de) 2010-12-28 2012-06-28 Bayer Animal Health Gmbh Makrocylischen Lactone und deren Verwendung und deren Kombinationen mit anderen Wirkstoffen
WO2012028556A1 (en) 2010-08-31 2012-03-08 Bayer Animal Health Gmbh Macrocyclic lactones and their use and their combinations with other active substances

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
NZ186851A (en) * 1977-04-11 1984-12-14 Merck & Co Inc Glycosyloxy derivatives of milbemycin and parasiticidal compositions
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
US4289760A (en) * 1980-05-02 1981-09-15 Merck & Co., Inc. 23-Keto derivatives of C-076 compounds
JPS57139081A (en) * 1981-02-23 1982-08-27 Sankyo Co Ltd 5-alkylcarbamoyloxy and 5-alkanesulfonyloxy derivative of antibiotic substance b-41 and preparation thereof
NZ201681A (en) * 1981-09-03 1985-11-08 Merck & Co Inc Avermectin derivatives and parasiticidal compositions
US4408059A (en) * 1981-12-04 1983-10-04 University Patents, Inc. Spiroketals useful as intermediates in the synthesis of milbemycin and avermectin macrolides
JPS5916894A (ja) * 1982-07-21 1984-01-28 Sankyo Co Ltd ミルベマイシンｄの５−アシルオキシ誘導体
JPS5920284A (ja) * 1982-07-23 1984-02-01 Sankyo Co Ltd ミルベマイシンｄの５−エ−テル誘導体及びその塩
JPS5920285A (ja) * 1982-07-23 1984-02-01 Sankyo Co Ltd ミルベマイシンｄの５−二塩基酸エステル誘導体及びその塩
US4582852A (en) * 1983-11-02 1986-04-15 Ciba-Geigy Corporation 14- and 15-hydroxy milbemycin derivatives for controlling plant and animal parasites
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
JPS60152490A (ja) * 1984-01-20 1985-08-10 Sankyo Co Ltd ミルベマイシンａ↓３，ａ↓４の５−二塩基酸エステル誘導体及びその塩
JPS60184085A (ja) * 1984-03-02 1985-09-19 Sankyo Co Ltd ミルベマイシン類の５−アミノ酸エステル誘導体
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use

Also Published As

Publication number Publication date
JPS60126289A (ja) 1985-07-05
DK164912B (da) 1992-09-07
KR850003539A (ko) 1985-06-20
DE3478438D1 (en) 1989-07-06
DK541584D0 (da) 1984-11-14
EP0142969A1 (en) 1985-05-29
AU3540984A (en) 1985-05-23
DK164912C (da) 1993-01-25
DK541584A (da) 1985-05-15
AU573766B2 (en) 1988-06-23
CA1235693A (en) 1988-04-26
ZA848826B (en) 1985-07-31
IL73508A (en) 1989-01-31
ES537650A0 (es) 1986-05-16
IL73508A0 (en) 1985-02-28
NZ210210A (en) 1987-04-30
US4760054A (en) 1988-07-26
EP0142969B1 (en) 1989-05-31
KR910006443B1 (ko) 1991-08-24

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