ES8604966A1 - Un procedimiento para preparar nuevos derivados de 1,3-dihi-dro-6-aminometil-7-hidroxi-furo-(3,4-c)-piridina - Google Patents

Un procedimiento para preparar nuevos derivados de 1,3-dihi-dro-6-aminometil-7-hidroxi-furo-(3,4-c)-piridina

Info

Publication number
ES8604966A1
ES8604966A1 ES546702A ES546702A ES8604966A1 ES 8604966 A1 ES8604966 A1 ES 8604966A1 ES 546702 A ES546702 A ES 546702A ES 546702 A ES546702 A ES 546702A ES 8604966 A1 ES8604966 A1 ES 8604966A1
Authority
ES
Spain
Prior art keywords
furo
aminomethyl
alkoxy
alkyl
pyridine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546702A
Other languages
English (en)
Other versions
ES546702A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of ES546702A0 publication Critical patent/ES546702A0/es
Publication of ES8604966A1 publication Critical patent/ES8604966A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS DE 1,3-DIHIDRO-6-AMINOMETIL-7-HIDROXI-FURO-(3,4-C)-PIRIDINA. COMPRENDE: A) TRATAR SUCESIVAMENTE A LOS DERIVADOS DE 6-METIL-7-HIDROXI-FURO-(3,4-C)-PIRIDINA DE FORMULA (III) CON ACIDO UN -CLORO-PEROXIBENZOICO, CON (CF3CO)2O Y CON MNO2, PARA PRODUCIR A LOS DERIVADOS DE 6-FENIL-7-HIDROXI-FURO-(3,4-C)-PIRIDINA DE FORMULA (II); B) HACER REACCIONAR A (II) CON HIDROXILAMINA Y CON NAOH, EN AGUA; Y C) HIDROGENAR AL PRODUCTO DE A) CON HIDROGENO EN PRESENCIA DE UN CATALIZADOR DE PD/C, EN ACIDO ACETICO, PARA OBTENER DERIVADOS DE 1,3-DIHIDRO-6-AMINOMETIL-7-HIDROXI-FURO-(3,4-C)-PIRIDINA DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: A1 Y A2, H, UN GRUPO INSATURADO O SATURADO DE CADENA LINEAL DE C 1 A 5, FENILO Y OTROS. SE UTILIZAN COMO ANTIALERGICOS Y ANTIHISTAMINICOS.
ES546702A 1984-09-05 1985-09-04 Un procedimiento para preparar nuevos derivados de 1,3-dihi-dro-6-aminometil-7-hidroxi-furo-(3,4-c)-piridina Expired ES8604966A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848422379A GB8422379D0 (en) 1984-09-05 1984-09-05 Derivatives

Publications (2)

Publication Number Publication Date
ES546702A0 ES546702A0 (es) 1986-03-01
ES8604966A1 true ES8604966A1 (es) 1986-03-01

Family

ID=10566274

Family Applications (1)

Application Number Title Priority Date Filing Date
ES546702A Expired ES8604966A1 (es) 1984-09-05 1985-09-04 Un procedimiento para preparar nuevos derivados de 1,3-dihi-dro-6-aminometil-7-hidroxi-furo-(3,4-c)-piridina

Country Status (23)

Country Link
JP (1) JPS6168490A (es)
AT (1) AT394557B (es)
BE (1) BE903121A (es)
CA (1) CA1300150C (es)
CH (1) CH665642A5 (es)
DE (1) DE3531747A1 (es)
DK (1) DK159318C (es)
ES (1) ES8604966A1 (es)
FI (1) FI82053C (es)
FR (2) FR2569562B1 (es)
GB (2) GB8422379D0 (es)
HK (1) HK10489A (es)
IE (1) IE58583B1 (es)
IT (1) IT1188188B (es)
LU (1) LU86053A1 (es)
MA (1) MA20517A1 (es)
MY (1) MY103211A (es)
NL (1) NL8502412A (es)
NO (1) NO160143C (es)
OA (1) OA08157A (es)
PT (1) PT81087B (es)
SE (1) SE461394B (es)
ZA (1) ZA856089B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8414559D0 (en) * 1984-06-07 1984-07-11 Scras Pyridine derivatives
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8907480D0 (en) * 1989-04-03 1989-05-17 Scaras Societe De Conseils De Separation of insomers of furo(3,4-c)pyridine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786269B (en) * 1977-11-25 1979-10-31 Scras New pyridine derivative,its preparation and use
IN156817B (es) * 1981-02-10 1985-11-09 Scras
ZA842029B (en) * 1983-04-05 1984-10-31 Scras Furo-(3,4-c)-pyridine derivatives preparation thereof and therapeutic compositions containing the same
GB8330517D0 (en) * 1983-11-16 1983-12-21 Scras 6-vinyl-furo-(3,4-c)pyridine derivatives

Also Published As

Publication number Publication date
FI82053B (fi) 1990-09-28
ES546702A0 (es) 1986-03-01
PT81087B (pt) 1987-10-20
NO853475L (no) 1986-03-06
FI853288A0 (fi) 1985-08-28
AT394557B (de) 1992-05-11
GB2164037A (en) 1986-03-12
DE3531747C2 (es) 1990-09-06
DK159318C (da) 1991-03-11
IT8522067A0 (it) 1985-09-05
LU86053A1 (fr) 1986-02-18
FR2569699A1 (fr) 1986-03-07
JPH0314830B2 (es) 1991-02-27
GB8520007D0 (en) 1985-09-18
GB2164037B (en) 1988-02-17
OA08157A (fr) 1987-03-31
CA1300150C (en) 1992-05-05
SE461394B (sv) 1990-02-12
DK402885A (da) 1986-03-06
GB8422379D0 (en) 1984-10-10
ZA856089B (en) 1986-03-26
BE903121A (fr) 1986-02-26
FR2569562B1 (fr) 1989-02-10
SE8504119D0 (sv) 1985-09-04
PT81087A (en) 1985-10-01
NO160143B (no) 1988-12-05
CH665642A5 (fr) 1988-05-31
JPS6168490A (ja) 1986-04-08
DK159318B (da) 1990-10-01
IT1188188B (it) 1988-01-07
NL8502412A (nl) 1986-04-01
DE3531747A1 (de) 1986-03-13
IE58583B1 (en) 1993-10-06
MY103211A (en) 1993-05-29
FI82053C (fi) 1991-01-10
SE8504119L (sv) 1986-03-06
FR2569562A1 (fr) 1986-03-07
IE852182L (en) 1986-03-05
MA20517A1 (fr) 1986-04-01
HK10489A (en) 1989-02-10
NO160143C (no) 1989-03-15
DK402885D0 (da) 1985-09-04
FI853288L (fi) 1986-03-06
ATA260285A (de) 1991-10-15

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