ES8601478A1 - Procedimiento de inmunoanalisis para determinar digoxina en una muestra de analisis. - Google Patents

Procedimiento de inmunoanalisis para determinar digoxina en una muestra de analisis.

Info

Publication number
ES8601478A1
ES8601478A1 ES525861A ES525861A ES8601478A1 ES 8601478 A1 ES8601478 A1 ES 8601478A1 ES 525861 A ES525861 A ES 525861A ES 525861 A ES525861 A ES 525861A ES 8601478 A1 ES8601478 A1 ES 8601478A1
Authority
ES
Spain
Prior art keywords
formula
digoxigenin
carrier
bond
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES525861A
Other languages
English (en)
Other versions
ES525861A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of ES8601478A1 publication Critical patent/ES8601478A1/es
Publication of ES525861A0 publication Critical patent/ES525861A0/es
Granted legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9453Cardioregulators, e.g. antihypotensives, antiarrhythmics
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds
    • Y10S436/817Steroids or hormones
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)

Abstract

PROCEDIMIENTO DE INMUNOANALISIS PARA DETERMINAR DIGOXINA EN UNA MUESTRA DE ANALISIS. COMPRENDE: PONER EN CONTACTO LA MUESTRA DE ANALISIS CON UNA FORMA MARCADA DE DIGOXINA O DIGOXIGENINA Y UN ANTICUERPO DIRIGIDO CONTRA UN CONJUGADO DE INMUNOGENO DE DIGOXIGENINA DE FORMULA (I) EN DONDE CANIER ES UN MATERIAL SOPORTE INMUNOGENICO R ES UN ENLACE O GRUPO DE ENLACE UNO DE 1 Y M ES UNO Y EL OTRO ES CERO N ES UN ENTERO DE 2 A 10 Y P ES UN PROMEDIO DE 1 A 50; Y DETERMINAR LA CANTIDAD RELATIVA DE LA FORMA MARCASDA DE DIGOXINA O DIOXIGENINA QUE SE LIGA CON EL ANTICUERPO COMO UNA FUNCION DE LA CONCENTRACION DE DIGOXINA EN LA MUESTRA DEL ANALISIS.
ES525861A 1982-09-23 1983-09-22 Procedimiento de inmunoanalisis para determinar digoxina en una muestra de analisis. Granted ES525861A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/422,217 US4469797A (en) 1982-09-23 1982-09-23 Digoxigenin immunogens, antibodies, labeled conjugates, and related derivatives

Publications (2)

Publication Number Publication Date
ES8601478A1 true ES8601478A1 (es) 1985-11-01
ES525861A0 ES525861A0 (es) 1985-11-01

Family

ID=23673888

Family Applications (1)

Application Number Title Priority Date Filing Date
ES525861A Granted ES525861A0 (es) 1982-09-23 1983-09-22 Procedimiento de inmunoanalisis para determinar digoxina en una muestra de analisis.

Country Status (8)

Country Link
US (1) US4469797A (es)
EP (1) EP0104527B1 (es)
JP (1) JPS5983056A (es)
AU (1) AU541321B2 (es)
CA (1) CA1213579A (es)
DE (1) DE3369887D1 (es)
ES (1) ES525861A0 (es)
IL (1) IL69126A0 (es)

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US4595656A (en) * 1984-01-06 1986-06-17 Becton Dickinson & Company Coupling agents and products produced therefrom
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US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
FR2601141A1 (fr) * 1986-07-02 1988-01-08 Centre Nat Rech Scient Produit de couplage a base d'haptene, utile notamment comme substance immunogene, anticorps correspondants et applications
US5034317A (en) * 1987-01-30 1991-07-23 Polaroid Corporation Enzyme controlled release system and organic conjugate reactant
US6326136B1 (en) * 1988-04-01 2001-12-04 Digene Corporation Macromolecular conjugate made using unsaturated aldehydes
DE3836656A1 (de) * 1988-10-27 1990-05-03 Boehringer Mannheim Gmbh Neue digoxigenin-derivate und ihre verwendung
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US7067110B1 (en) 1999-07-21 2006-06-27 Emd Lexigen Research Center Corp. Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
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FR2310766A1 (fr) * 1975-05-16 1976-12-10 Nativelle Sa Ets Derives de cardenolides, procede de preparation et application a titre de medicament
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CA1119163A (en) * 1977-09-01 1982-03-02 Ravi K. Varma Digoxigenin derivatives

Also Published As

Publication number Publication date
EP0104527B1 (en) 1987-02-25
JPS5983056A (ja) 1984-05-14
EP0104527A1 (en) 1984-04-04
AU1641683A (en) 1984-03-29
US4469797A (en) 1984-09-04
CA1213579A (en) 1986-11-04
DE3369887D1 (en) 1987-04-02
JPH0231346B2 (es) 1990-07-12
ES525861A0 (es) 1985-11-01
IL69126A0 (en) 1983-10-31
AU541321B2 (en) 1985-01-03

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