ES8405359A1 - Procedimiento para preparar derivados farmaceuticamente aceptables de 2-dietilamino-metiletil-cis-1-hidroxi-(biciclohexil)-2-carboxilato. - Google Patents
Procedimiento para preparar derivados farmaceuticamente aceptables de 2-dietilamino-metiletil-cis-1-hidroxi-(biciclohexil)-2-carboxilato.Info
- Publication number
- ES8405359A1 ES8405359A1 ES521183A ES521183A ES8405359A1 ES 8405359 A1 ES8405359 A1 ES 8405359A1 ES 521183 A ES521183 A ES 521183A ES 521183 A ES521183 A ES 521183A ES 8405359 A1 ES8405359 A1 ES 8405359A1
- Authority
- ES
- Spain
- Prior art keywords
- bicyclohexyl
- diethylamino
- carboxylate
- hydroxy
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 2-diethylamino-1-methyl ethyl Chemical class 0.000 title abstract 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 239000012265 solid product Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/24—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/12—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT20538/82A IT1190755B (it) | 1982-04-01 | 1982-04-01 | Procedimento per la preparazione di derivati di 2-dietilamino-1-metiletil cis-1-idrossi-(bicicloesil)-2-carbossilato |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES521183A0 ES521183A0 (es) | 1984-06-01 |
| ES8405359A1 true ES8405359A1 (es) | 1984-06-01 |
Family
ID=11168449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES521183A Expired ES8405359A1 (es) | 1982-04-01 | 1983-03-30 | Procedimiento para preparar derivados farmaceuticamente aceptables de 2-dietilamino-metiletil-cis-1-hidroxi-(biciclohexil)-2-carboxilato. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5011974A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0091078B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPS591452A (cg-RX-API-DMAC7.html) |
| KR (1) | KR910002686B1 (cg-RX-API-DMAC7.html) |
| AR (1) | AR243863A1 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE23854T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU570201B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA1214470A (cg-RX-API-DMAC7.html) |
| DE (1) | DE3367909D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK164046C (cg-RX-API-DMAC7.html) |
| ES (1) | ES8405359A1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI77648C (cg-RX-API-DMAC7.html) |
| GR (1) | GR78791B (cg-RX-API-DMAC7.html) |
| IL (1) | IL68281A (cg-RX-API-DMAC7.html) |
| IN (1) | IN158129B (cg-RX-API-DMAC7.html) |
| IT (1) | IT1190755B (cg-RX-API-DMAC7.html) |
| NO (1) | NO161218C (cg-RX-API-DMAC7.html) |
| PH (1) | PH23299A (cg-RX-API-DMAC7.html) |
| PT (1) | PT76491B (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106631760B (zh) * | 2015-10-29 | 2019-05-28 | 上海医药工业研究院 | 顺-1-羟基-[1,1’-双(环己烷)]-2-羧酸的制备工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3156725A (en) * | 1962-04-18 | 1964-11-10 | Smith Kline French Lab | Substituted 2-phenoxy and phenylthio-cyclopropylamines |
| NL296693A (cg-RX-API-DMAC7.html) * | 1962-08-16 | |||
| AU423221B2 (en) * | 1967-07-29 | 1972-04-14 | LABORATORIO GUIDOTTI & C. Sp. A | 2 hydroxycyclohexanecarboxylic substituted acids, basic esters thereof and salts showing a choleretic and antispastic activity |
| AT288348B (de) * | 1967-09-20 | 1971-02-25 | Guidotti & C Spa Labor | Verfahren zur Herstellung von neuen basischen Estern der 2-Phenyl- oder 2-Cyclohexyl-2-hydroxycyclohexancarbonsäure sowie von deren Säureadditions- und quaternären Salzen |
| US3700675A (en) * | 1970-09-11 | 1972-10-24 | Luigi Turbanti | Ester of 2-hydroxy-cyclohexane-2-substituted carboxylic acids |
| IT1100581B (it) * | 1978-11-24 | 1985-09-28 | Lab Guidotti & C Spa | Procedimento per la fabbricazione di esteri easici di acidi idrossicicicloesancarbossilici sostituti |
-
1982
- 1982-04-01 IT IT20538/82A patent/IT1190755B/it active
-
1983
- 1983-03-29 DK DK143083A patent/DK164046C/da not_active IP Right Cessation
- 1983-03-29 EP EP83103129A patent/EP0091078B1/en not_active Expired
- 1983-03-29 PH PH28721A patent/PH23299A/en unknown
- 1983-03-29 NO NO831180A patent/NO161218C/no unknown
- 1983-03-29 AT AT83103129T patent/ATE23854T1/de not_active IP Right Cessation
- 1983-03-29 DE DE8383103129T patent/DE3367909D1/de not_active Expired
- 1983-03-30 ES ES521183A patent/ES8405359A1/es not_active Expired
- 1983-03-30 CA CA000424888A patent/CA1214470A/en not_active Expired
- 1983-03-30 AR AR83292613A patent/AR243863A1/es active
- 1983-03-31 PT PT76491A patent/PT76491B/pt not_active IP Right Cessation
- 1983-03-31 GR GR70954A patent/GR78791B/el unknown
- 1983-03-31 FI FI831118A patent/FI77648C/fi not_active IP Right Cessation
- 1983-03-31 AU AU13121/83A patent/AU570201B2/en not_active Ceased
- 1983-03-31 IN IN388/CAL/83A patent/IN158129B/en unknown
- 1983-03-31 KR KR1019830001320A patent/KR910002686B1/ko not_active Expired
- 1983-04-01 JP JP58058566A patent/JPS591452A/ja active Granted
- 1983-04-01 IL IL68281A patent/IL68281A/xx not_active IP Right Cessation
-
1989
- 1989-03-01 US US07/318,520 patent/US5011974A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO161218B (no) | 1989-04-10 |
| IN158129B (cg-RX-API-DMAC7.html) | 1986-09-13 |
| EP0091078A1 (en) | 1983-10-12 |
| PT76491A (en) | 1983-04-01 |
| DK164046C (da) | 1992-10-12 |
| GR78791B (cg-RX-API-DMAC7.html) | 1984-10-02 |
| IT1190755B (it) | 1988-02-24 |
| AR243863A1 (es) | 1993-09-30 |
| DK143083A (da) | 1983-10-02 |
| CA1214470A (en) | 1986-11-25 |
| AU1312183A (en) | 1983-10-06 |
| IL68281A (en) | 1987-09-16 |
| DE3367909D1 (en) | 1987-01-15 |
| US5011974A (en) | 1991-04-30 |
| JPH0480899B2 (cg-RX-API-DMAC7.html) | 1992-12-21 |
| AU570201B2 (en) | 1988-03-10 |
| ATE23854T1 (de) | 1986-12-15 |
| EP0091078B1 (en) | 1986-11-26 |
| PH23299A (en) | 1989-06-30 |
| JPS591452A (ja) | 1984-01-06 |
| IT8220538A0 (it) | 1982-04-01 |
| DK143083D0 (da) | 1983-03-29 |
| IL68281A0 (en) | 1983-07-31 |
| FI831118A0 (fi) | 1983-03-31 |
| FI77648C (fi) | 1989-04-10 |
| NO161218C (no) | 1989-07-19 |
| DK164046B (da) | 1992-05-04 |
| PT76491B (en) | 1985-12-10 |
| ES521183A0 (es) | 1984-06-01 |
| FI77648B (fi) | 1988-12-30 |
| FI831118L (fi) | 1983-10-02 |
| KR910002686B1 (ko) | 1991-05-03 |
| NO831180L (no) | 1983-10-03 |
| KR840004061A (ko) | 1984-10-06 |
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