ZA876033B - Process for the preparation of a low-prothrombin preparation of vitamin k-dependent coagulation factors,and an agent obtainable therewith - Google Patents

Process for the preparation of a low-prothrombin preparation of vitamin k-dependent coagulation factors,and an agent obtainable therewith

Info

Publication number
ZA876033B
ZA876033B ZA876033A ZA876033A ZA876033B ZA 876033 B ZA876033 B ZA 876033B ZA 876033 A ZA876033 A ZA 876033A ZA 876033 A ZA876033 A ZA 876033A ZA 876033 B ZA876033 B ZA 876033B
Authority
ZA
South Africa
Prior art keywords
preparation
vitamin
low
coagulation factors
prothrombin
Prior art date
Application number
ZA876033A
Inventor
Hartmut Loebermann
Loebermann Hartmut
Rainer Peter
Peter Rainer
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of ZA876033B publication Critical patent/ZA876033B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/647Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
ZA876033A 1986-08-16 1987-08-14 Process for the preparation of a low-prothrombin preparation of vitamin k-dependent coagulation factors,and an agent obtainable therewith ZA876033B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863627762 DE3627762A1 (en) 1986-08-16 1986-08-16 METHOD FOR PRODUCING A LOW PROTHROMBINE PREPARATION VITAMIN K-DEPENDENT COagulation FACTORS, AND A SUBSTANCE AVAILABLE AFTER THIS

Publications (1)

Publication Number Publication Date
ZA876033B true ZA876033B (en) 1988-04-27

Family

ID=6307487

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA876033A ZA876033B (en) 1986-08-16 1987-08-14 Process for the preparation of a low-prothrombin preparation of vitamin k-dependent coagulation factors,and an agent obtainable therewith

Country Status (9)

Country Link
EP (1) EP0256522A3 (en)
JP (1) JPS6351336A (en)
AU (1) AU7687587A (en)
DE (1) DE3627762A1 (en)
DK (1) DK425587A (en)
FI (1) FI873514A (en)
IL (1) IL83541A0 (en)
PT (1) PT85540B (en)
ZA (1) ZA876033B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4081432A (en) * 1977-07-25 1978-03-28 Monsanto Company Method of separating a Factor IX preparation from plasma using ethylene-maleic anhydride polymers
SU973129A1 (en) * 1981-03-27 1982-11-15 Московский Ордена Ленина,Ордена Октябрьской Революции И Ордена Трудового Красного Знамени Государственный Университет Им.М.В.Ломоносова Method of producing prothrobin i
US4447416A (en) * 1982-04-28 1984-05-08 American National Red Cross Plasma protein concentrates of reduced thrombogenicity and their use in clinical replacement therapy

Also Published As

Publication number Publication date
EP0256522A2 (en) 1988-02-24
FI873514A (en) 1988-02-17
DK425587D0 (en) 1987-08-14
PT85540A (en) 1987-09-01
DE3627762A1 (en) 1988-02-18
PT85540B (en) 1989-12-29
JPS6351336A (en) 1988-03-04
AU7687587A (en) 1988-02-18
IL83541A0 (en) 1988-01-31
EP0256522A3 (en) 1989-02-01
FI873514A0 (en) 1987-08-13
DK425587A (en) 1988-02-17

Similar Documents

Publication Publication Date Title
IL73159A0 (en) Carboxyalkenamidocephalosporines,process for the preparation thereof and methods for the use thereof
HUT45523A (en) Herbicides comprising pyridine-sulfonamide derivatives and process for producing the active ingredients
EP0187620A3 (en) Pyrrolo-pyrroles, process for their preparation and use
PH22975A (en) Substituted hydrazones, process for the preparation and their use
EP0260121A3 (en) Inosose derivatives, production and use thereof
ZA862959B (en) Process for the preparation of imidates,and new aryl-substituted imidates
EP0255601A3 (en) Dialkylnaleinimides, process for their preparation and their use as herbicide
EP0252357A3 (en) Process for the preparation of (4-hydroxyphenyl)-4-hydroxy-benzoate, and its use
EP0264744A3 (en) Process for the preparation of 4,4'-diaminodiphenylmethane and its derivatives.
EP0259817A3 (en) Hypofluorites and bis-hypofluorites, and process for preparing same
GB2200112B (en) Process for the selective para-bromination of phenol and its derivatives
EP0256480A3 (en) Process for the catalic trans-halogenation of a polyiodo-benzene and, in particular, of a di-iodo-benzene
HUT44906A (en) Herbicides comprising imino-oxazolidine derivatives and process for producing the active ingredients
ZA876033B (en) Process for the preparation of a low-prothrombin preparation of vitamin k-dependent coagulation factors,and an agent obtainable therewith
EP0243607A3 (en) Process for manufacturing bicarbamates, and new bicarbamates
ZA886915B (en) 4-azasaccharines,4-aza-dihydro-or-tetrahydro-saccharines and processes for the preparation thereof
DE3561058D1 (en) Hydroxy-thia-alcanes, process for their preparation and their uses
ZA876808B (en) Arylethanolamines,processes for the preparation thereof,and the use thereof for promoting production
ZA867886B (en) A copolymer,a process for its preparation and its use as enzyme supports
EP0267537A3 (en) Process for the preparation of vinylglyoxal derivatives, vinylglyoxal derivatives and their use
ZA856527B (en) Process for the preparation of aromatic-1,4-oxazepinones and thiones
IL84987A0 (en) Nitrohaloalkoxybenzenes,a process for their preparation,and their use
PL266142A1 (en) Weedicidal specific and the method of manufacturing of new derivatives of 2-phenylaceto-cyclohexanotrion-1,3,5
PL276723A1 (en) Method for preparation of the new, n-phenylcarbamyle derivatives of difurylethane and difurylvinylchloride
EP0371362A3 (en) Process for the preparation of 1-nitro, 2-carboxy-anthraquinone