ES8405072A1 - Un procedimiento para la preparacion de un vector de trans- ferencia dna - Google Patents
Un procedimiento para la preparacion de un vector de trans- ferencia dnaInfo
- Publication number
- ES8405072A1 ES8405072A1 ES504968A ES504968A ES8405072A1 ES 8405072 A1 ES8405072 A1 ES 8405072A1 ES 504968 A ES504968 A ES 504968A ES 504968 A ES504968 A ES 504968A ES 8405072 A1 ES8405072 A1 ES 8405072A1
- Authority
- ES
- Spain
- Prior art keywords
- growth
- growth hormone
- bovine
- bovine pre
- hormone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241000283690 Bos taurus Species 0.000 title abstract 2
- 108010057578 pregrowth hormone Proteins 0.000 title abstract 2
- 108010051696 Growth Hormone Proteins 0.000 title 1
- 102000018997 Growth Hormone Human genes 0.000 title 1
- 239000000122 growth hormone Substances 0.000 title 1
- 108010006025 bovine growth hormone Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fodder In General (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UN VECTOR DE TRANSFERENCIA DE DNA, QUE TIENE APLICACION EN EL MANTENIMIENTO Y LA REPLICACION DE UNA SECUENCIA DESOXINUCLEOTIDICA QUE CODIFICA PARA LA PREHORMONA BOVINA DEL CRECIMIENTO.CONSISTE EN LA REACCION DE UNA SECUENCIA DESOXINUCLEOTIDICA QUE CODIFICA PARA LA PREHORMONA BOVINA DEL CRECIMIENTO CON UNA MOLECULA DE DNA, PREPARADA POR CORTE DE UN VECTOR DE TRANSFERENCIA CON UNA ENZIMA DE RESTRICCION, TAL COMO HAE II. EL PRODUCTO CORTADO SE INCUBA CON UNA ENZIMA DE GRUPO FORMADO POR FRAGMENTO KLENOW DE LA DNA POLIMERASA I, DNA POLIMERASADE T4 O EXONUCLEASA 3-5.)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18134880A | 1980-08-26 | 1980-08-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8405072A1 true ES8405072A1 (es) | 1984-05-16 |
ES504968A0 ES504968A0 (es) | 1984-05-16 |
Family
ID=22663908
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES504968A Granted ES504968A0 (es) | 1980-08-26 | 1981-08-25 | Un procedimiento para la preparacion de un vector de trans- ferencia dna |
ES514526A Granted ES514526A0 (es) | 1980-08-26 | 1982-07-29 | Un procedimiento para la preparacion de una proteina de fusion. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES514526A Granted ES514526A0 (es) | 1980-08-26 | 1982-07-29 | Un procedimiento para la preparacion de una proteina de fusion. |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP0047600B1 (es) |
JP (2) | JP2534221B2 (es) |
KR (1) | KR830007822A (es) |
AT (1) | ATE72833T1 (es) |
AU (1) | AU544453B2 (es) |
CA (1) | CA1225948A (es) |
CZ (1) | CZ280596B6 (es) |
DD (4) | DD212403A5 (es) |
DE (1) | DE3177273D1 (es) |
DK (1) | DK372881A (es) |
ES (2) | ES504968A0 (es) |
FI (1) | FI812614L (es) |
GR (1) | GR74350B (es) |
HU (1) | HU195535B (es) |
IE (1) | IE52755B1 (es) |
IL (1) | IL63628A (es) |
NZ (1) | NZ198050A (es) |
PH (2) | PH21216A (es) |
PL (1) | PL232797A1 (es) |
PT (1) | PT73569B (es) |
RO (1) | RO105533B1 (es) |
SU (1) | SU1471949A3 (es) |
YU (1) | YU44962B (es) |
ZA (1) | ZA815696B (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4443539A (en) * | 1980-02-05 | 1984-04-17 | The Upjohn Company | Process for preparing bovine growth hormone |
JPS58996A (ja) * | 1981-06-01 | 1983-01-06 | ザ・ボ−ド・オブ・トラステイ−ズ・ミシガンステ−トユニバ−シテイ− | 細菌中での牛成長ホルモン遺伝子のクロ−ン化 |
NZ201918A (en) * | 1981-09-18 | 1987-04-30 | Genentech Inc | N-terminal methionyl analogues of bovine growth hormone |
US5254463A (en) * | 1981-09-18 | 1993-10-19 | Genentech, Inc. | Method for expression of bovine growth hormone |
ATE83799T1 (de) * | 1981-09-18 | 1993-01-15 | Genentech Inc | Verfahren und produkte zur leichten mikrobiologischen expression von dns-sequenzen. |
DE3380262D1 (en) * | 1982-05-25 | 1989-08-31 | Lilly Co Eli | Cloning vectors for expression of exogenous protein |
EP0103395A3 (en) * | 1982-08-17 | 1985-05-22 | Biogen N.V. | Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield |
JPS59501852A (ja) * | 1982-09-16 | 1984-11-08 | アムジエン | 鳥類の成長ホルモン |
CA1341012C (en) | 1982-09-27 | 2000-06-06 | Biogen, Inc. | Dna sequences, recombinant dna molecules and processes for producing swine growth hormone-like polypeptides |
AU2092983A (en) * | 1982-11-08 | 1984-05-17 | Genentech Inc. | Porcine growth hormone produced by recombinant dna technology |
ZA837173B (en) * | 1982-11-08 | 1984-05-30 | Univ Case Western Reserve | Genomic bovine growth hormone |
EP0111814A3 (en) * | 1982-12-16 | 1985-08-14 | Mgi Pharma, Inc. | The cloning and expression of nucleotide sequences encoding bovine growth hormone |
DE3247922A1 (de) * | 1982-12-24 | 1984-06-28 | Boehringer Ingelheim International GmbH, 6507 Ingelheim | Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten |
JPS6011557A (ja) * | 1983-04-19 | 1985-01-21 | ジエネツクス・コ−ポレイシヨン | クロ−ンヒツジ成長ホルモン遺伝子 |
US4755465A (en) * | 1983-04-25 | 1988-07-05 | Genentech, Inc. | Secretion of correctly processed human growth hormone in E. coli and Pseudomonas |
US4859600A (en) * | 1983-04-25 | 1989-08-22 | Genentech, Inc. | Recombinant procaryotic cell containing correctly processed human growth hormone |
US5198361A (en) * | 1983-07-15 | 1993-03-30 | Bio-Technology General Corp. | Plasmids for production of met-asp-gln bovine growth hormone, hosts containing the plasmids, products manufactured thereby and related methods |
BG49718A3 (en) * | 1983-07-15 | 1992-01-15 | Bio Technology General Corp | Method for preparing of polypeptid with superoxiddismutasne activitty |
US4521409A (en) * | 1983-10-03 | 1985-06-04 | Cornell Research Foundation, Inc. | Use of growth hormone to enhance ruminant mammary development |
EP0147178B1 (en) * | 1983-12-23 | 1991-08-14 | Pfizer Inc. | Expression plasmids for improved production of heterologous protein in bacteria |
US4935370A (en) * | 1983-12-23 | 1990-06-19 | Pfizer Inc. | Expression plasmids for improved production of heterologous protein in bacteria |
US5489529A (en) * | 1984-07-19 | 1996-02-06 | De Boer; Herman A. | DNA for expression of bovine growth hormone |
US5037806A (en) | 1985-02-22 | 1991-08-06 | Monsanto Company | Biologically active method using somatotropins |
US4861868A (en) * | 1985-02-22 | 1989-08-29 | Monsanto Company | Production of proteins in procaryotes |
DE3685424D1 (de) | 1985-06-26 | 1992-06-25 | Upjohn Co | Solubilisation und oxidation von somatotropin aus transformierten mikroorganismen. |
US4786501A (en) * | 1985-07-15 | 1988-11-22 | International Minerals & Chemical Corp. | Cylindrical implants for the controlled release of growth hormones |
US5631227A (en) * | 1985-09-18 | 1997-05-20 | The Upjohn Company | Somatotropin analogs |
EP0236452B1 (en) * | 1985-09-18 | 1990-10-31 | The Upjohn Company | Enhanced bioactivity of mammalian somatotropin through selective deamidation |
ES2019874B3 (es) * | 1986-10-08 | 1991-07-16 | Upjohn Co | Bioactividad mejorada de somatotropina de mamiferos mediante desamidacion selectiva. |
US5215896A (en) * | 1987-03-20 | 1993-06-01 | Creative Biomolecules, Inc. | Leader sequences for the production of recombinant proteins |
US5013653A (en) | 1987-03-20 | 1991-05-07 | Creative Biomolecules, Inc. | Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage |
US5268284A (en) * | 1988-03-11 | 1993-12-07 | The Upjohn Company | Ribosome binding site |
JP2787729B2 (ja) * | 1990-08-02 | 1998-08-20 | 株式会社ニッポンジーン | 組換え型ミンク成長ホルモン遺伝子、組換え型ミンクプレ成長ホルモン遺伝子、ミンク成長ホルモン又はミンクプレ成長ホルモン形質転換プラスミド、及び、ミンク成長ホルモン又はミンクプレ成長ホルモン形質転換大腸菌 |
KR100847386B1 (ko) | 2000-12-26 | 2008-07-18 | 몬산토 테크놀로지 엘엘씨 | 소마토트로핀의 발현을 위한 재조합 dna 벡터 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU257278A (en) * | 1977-11-08 | 1984-02-29 | Genentech Inc | Process for obtaining a recombinat clone carrier |
IE48385B1 (en) * | 1978-08-11 | 1984-12-26 | Univ California | Synthesis of a eucaryotic protein by a microorganism |
ZA802992B (en) * | 1979-06-01 | 1981-10-28 | Univ California | Human pre-growth hormone |
IL59690A (en) * | 1980-03-24 | 1983-11-30 | Yeda Res & Dev | Production of bovine growth hormone by microorganisms and modified microorganisms adapted to produce it |
-
1981
- 1981-08-10 IE IE1822/81A patent/IE52755B1/en unknown
- 1981-08-12 CA CA000383687A patent/CA1225948A/en not_active Expired
- 1981-08-14 NZ NZ198050A patent/NZ198050A/en unknown
- 1981-08-14 GR GR65802A patent/GR74350B/el unknown
- 1981-08-18 ZA ZA815696A patent/ZA815696B/xx unknown
- 1981-08-20 IL IL63628A patent/IL63628A/xx not_active IP Right Cessation
- 1981-08-21 DE DE8181303824T patent/DE3177273D1/de not_active Expired - Lifetime
- 1981-08-21 EP EP81303824A patent/EP0047600B1/en not_active Expired - Lifetime
- 1981-08-21 AT AT81303824T patent/ATE72833T1/de not_active IP Right Cessation
- 1981-08-24 DK DK372881A patent/DK372881A/da unknown
- 1981-08-24 PH PH26092A patent/PH21216A/en unknown
- 1981-08-25 FI FI812614A patent/FI812614L/fi not_active Application Discontinuation
- 1981-08-25 JP JP56133231A patent/JP2534221B2/ja not_active Expired - Lifetime
- 1981-08-25 PT PT73569A patent/PT73569B/pt not_active IP Right Cessation
- 1981-08-25 AU AU74496/81A patent/AU544453B2/en not_active Expired
- 1981-08-25 RO RO105165A patent/RO105533B1/ro unknown
- 1981-08-25 HU HU812462A patent/HU195535B/hu not_active IP Right Cessation
- 1981-08-25 ES ES504968A patent/ES504968A0/es active Granted
- 1981-08-25 YU YU2062/81A patent/YU44962B/xx unknown
- 1981-08-25 PL PL23279781A patent/PL232797A1/xx unknown
- 1981-08-26 DD DD81252964A patent/DD212403A5/de unknown
- 1981-08-26 DD DD81252962A patent/DD211581A5/de unknown
- 1981-08-26 DD DD81252965A patent/DD212267A5/de unknown
- 1981-08-26 KR KR1019810003125A patent/KR830007822A/ko unknown
- 1981-08-26 DD DD81232811A patent/DD204711A5/de unknown
- 1981-08-26 CZ CS816360A patent/CZ280596B6/cs not_active IP Right Cessation
- 1981-10-23 SU SU813345603A patent/SU1471949A3/ru active
-
1982
- 1982-07-29 ES ES514526A patent/ES514526A0/es active Granted
-
1984
- 1984-03-15 PH PH30403A patent/PH22847A/en unknown
-
1996
- 1996-02-29 JP JP8043645A patent/JP2763024B2/ja not_active Expired - Lifetime
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