ES8305829A1 - Un procedimiento para la produccion de una proteina de fusion. - Google Patents

Un procedimiento para la produccion de una proteina de fusion.

Info

Publication number
ES8305829A1
ES8305829A1 ES514528A ES514528A ES8305829A1 ES 8305829 A1 ES8305829 A1 ES 8305829A1 ES 514528 A ES514528 A ES 514528A ES 514528 A ES514528 A ES 514528A ES 8305829 A1 ES8305829 A1 ES 8305829A1
Authority
ES
Spain
Prior art keywords
somatostatin
precursors
preprosomatostatin
prosomatostatin
sequence coding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514528A
Other languages
English (en)
Other versions
ES514528A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of ES8305829A1 publication Critical patent/ES8305829A1/es
Publication of ES514528A0 publication Critical patent/ES514528A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UN VECTOR DE TRANSFERENCIA DE DNA QUE CONTIENE UNA SECUENCIA NUCLEOTIDICA QUE CODIFICA PARA UNA SOMATOSTATINA O PARA UN PRECURSOR DE SOMATOSTATINA. SE TRANSFORMA UN MICROORGANISMO MEDIANTE UN VECTOR DE TRANSFERENCIA DE DNA, PARA USO EN EL MANTENIMIENTO Y LA REPLICACION DE UNA SECUENCIA DESOXINUCLEOTIDICA QUE CODIFICA PARA UNA SUMATOSTATINA O PARA UN PRECURSOR DE SOMATOSTATINA SELECCIONADO ENTRE EL GRUPO FORMADO POR PREPRO-SOMATOSTATINA-1, PROSOMATOSTATINA-1, PREPROSOMATOSTATINA-2, PROSOMATOSTATINA-2 Y SOMATOSTATINA-2. SE INCUBA EL MICROORGANISMO TRANSFORMADO Y SE AISLA LA PROTEINA DESEADA.
ES514528A 1980-08-25 1982-07-29 Un procedimiento para la produccion de una proteina de fusion. Granted ES514528A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18104680A 1980-08-25 1980-08-25

Publications (2)

Publication Number Publication Date
ES8305829A1 true ES8305829A1 (es) 1983-04-16
ES514528A0 ES514528A0 (es) 1983-04-16

Family

ID=22662682

Family Applications (2)

Application Number Title Priority Date Filing Date
ES504929A Expired ES8302095A1 (es) 1980-08-25 1981-08-24 Un procedimiento para la preparacion de un sector de transferencia de acido dexoxirribonucleico (= dna).
ES514528A Granted ES514528A0 (es) 1980-08-25 1982-07-29 Un procedimiento para la produccion de una proteina de fusion.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES504929A Expired ES8302095A1 (es) 1980-08-25 1981-08-24 Un procedimiento para la preparacion de un sector de transferencia de acido dexoxirribonucleico (= dna).

Country Status (19)

Country Link
EP (1) EP0046669B1 (es)
JP (1) JPS57126455A (es)
KR (1) KR830006424A (es)
AT (1) ATE9993T1 (es)
AU (1) AU549647B2 (es)
DD (1) DD202451A5 (es)
DE (1) DE3166845D1 (es)
DK (1) DK372781A (es)
ES (2) ES8302095A1 (es)
FI (1) FI812593L (es)
GR (1) GR74628B (es)
IE (1) IE52122B1 (es)
IL (1) IL63629A (es)
NZ (1) NZ198063A (es)
PH (1) PH20862A (es)
PL (1) PL232798A1 (es)
PT (1) PT73568B (es)
YU (1) YU206181A (es)
ZA (1) ZA815671B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2521657B2 (ja) * 1983-07-15 1996-08-07 インペリアル・ケミカル・インダストリーズ・ピーエルシー 組換ｄｎａ分子及びこれを含有する形質転換宿主細胞
DE3326520A1 (de) * 1983-07-22 1985-01-31 Hubert Prof. Dr. 2000 Hamburg Köster Verfahren zur definierten verknuepfung doppelhelikaler dna-fragmente mittels einer linker-dna sowie als linker-dna geeignete oligonucletide
WO1985000831A1 (en) * 1983-08-10 1985-02-28 Amgen Microbial expression of insulin-like growth factor
IT1198443B (it) * 1984-03-30 1988-12-21 Serono Ist Farm Espressione genetica di polipeptidi ibridi contenenti la sequenza della somatostatina
DE3545237A1 (de) * 1985-12-20 1987-06-25 Juergen Dr Med Schrezenmeir Vorrichtung fuer die aufnahme und zum einbringen von geweben in den menschlichen koerper sowie hierfuer verwendbares instrument
US6818739B2 (en) * 1999-12-03 2004-11-16 Ndsu Research Foundation Somatostatins
DE602006004028D1 (de) 2005-01-06 2009-01-15 Halton Oy Automatisches Verschiebungsbelüftungssystem mit Erhitzungsmodus
EP1989140A1 (en) * 2006-02-27 2008-11-12 A. CELLI NONWOVENS S.p.A. Winding rod for winding reels of weblike material, and machine that uses said rod

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU257278A (en) * 1977-11-08 1984-02-29 Genentech Inc Process for obtaining a recombinat clone carrier
NO783724L (no) * 1977-11-08 1979-05-09 Genentech Inc Syntetisk dna samt fremgangsmaate til dets fremstilling
AT373280B (de) * 1977-11-08 1984-01-10 Genentech Inc Verfahren zur erzeugung eines spezifischen polypeptids aus einem mikrobiellen rekombinations -clonbildungstraeger

Also Published As

Publication number Publication date
IE52122B1 (en) 1987-06-24
IE811823L (en) 1982-02-26
DK372781A (da) 1982-02-26
IL63629A0 (en) 1981-11-30
PL232798A1 (en) 1983-07-18
AU7447881A (en) 1982-03-04
KR830006424A (ko) 1983-09-24
EP0046669B1 (en) 1984-10-24
PH20862A (en) 1987-05-19
ES504929A0 (es) 1983-01-01
ZA815671B (en) 1982-08-25
PT73568A (en) 1981-09-01
PT73568B (en) 1982-11-09
EP0046669A1 (en) 1982-03-03
ES514528A0 (es) 1983-04-16
AU549647B2 (en) 1986-02-06
ATE9993T1 (de) 1984-11-15
FI812593L (fi) 1982-02-26
DE3166845D1 (en) 1984-11-29
IL63629A (en) 1985-06-30
DD202451A5 (de) 1983-09-14
ES8302095A1 (es) 1983-01-01
GR74628B (es) 1984-06-29
YU206181A (en) 1984-04-30
NZ198063A (en) 1984-12-14
JPS57126455A (en) 1982-08-06

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